tetraethylenepentamine-574 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

196 genes differentially expressed following the tetraethylenepentamine-574 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACAA2 acetyl-CoA acyltransferase 2
AMOT angiomotin
AP3S2 adaptor-related protein complex 3, sigma 2 subunit
APOC1 apolipoprotein C-I
ATP1B2 ATPase, Na+/K+ transporting, beta 2 polypeptide
ATP8B2 ATPase, aminophospholipid transporter, class I, type 8B, member 2
AVIL advillin
BAIAP3 BAI1-associated protein 3
BCL6 B-cell CLL/lymphoma 6
BMP10 bone morphogenetic protein 10
BNIP1 BCL2/adenovirus E1B 19kDa interacting protein 1
C1ORF54 chromosome 1 open reading frame 54
CACNB1 calcium channel, voltage-dependent, beta 1 subunit
CALCRL calcitonin receptor-like
CAMK1D calcium/calmodulin-dependent protein kinase ID
CASP10 caspase 10, apoptosis-related cysteine peptidase
CFAP46 cilia and flagella associated protein 46
CFAP70 cilia and flagella associated protein 70
CFTR cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)
CIDEB cell death-inducing DFFA-like effector b
CLEC10A C-type lectin domain family 10, member A
CLIP2 CAP-GLY domain containing linker protein 2
CNTD2 cyclin N-terminal domain containing 2
COL4A3 collagen, type IV, alpha 3 (Goodpasture antigen)
DAZL deleted in azoospermia-like
DENND3 DENN/MADD domain containing 3
EDNRA endothelin receptor type A
EIF4E2 eukaryotic translation initiation factor 4E family member 2
ELAC2 elaC ribonuclease Z 2
EPS8L3 EPS8-like 3
FGFBP1 fibroblast growth factor binding protein 1
GDF5 growth differentiation factor 5
GNAO1 guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O
HMOX2 heme oxygenase 2
HNF4A hepatocyte nuclear factor 4, alpha
HOXB7 homeobox B7
HOXD1 homeobox D1
HRH1 histamine receptor H1
IFIT3 interferon-induced protein with tetratricopeptide repeats 3
IGF1 insulin-like growth factor 1 (somatomedin C)
IGKV1D-13 immunoglobulin kappa variable 1D-13
IKZF1 IKAROS family zinc finger 1 (Ikaros)
IL18RAP interleukin 18 receptor accessory protein
IL6R interleukin 6 receptor
IRF8 interferon regulatory factor 8
KANK1 KN motif and ankyrin repeat domains 1
KIAA0391 KIAA0391
KIAA1045 KIAA1045
KIR2DL4 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 4
KLHL18 kelch-like family member 18
LENEP lens epithelial protein
LINC00574 long intergenic non-protein coding RNA 574
LRRN3 leucine rich repeat neuronal 3
LTBP4 latent transforming growth factor beta binding protein 4
LUZP1 leucine zipper protein 1
LZTR1 leucine-zipper-like transcription regulator 1
MAP4K1 mitogen-activated protein kinase kinase kinase kinase 1
MAPK3 mitogen-activated protein kinase 3
MARK1 MAP/microtubule affinity-regulating kinase 1
MID1 midline 1
MTERF4 mitochondrial transcription termination factor 4
NCKIPSD NCK interacting protein with SH3 domain
NPR2 natriuretic peptide receptor 2
OAS2 2'-5'-oligoadenylate synthetase 2, 69/71kDa
OR10H1 olfactory receptor, family 10, subfamily H, member 1
P2RX1 purinergic receptor P2X, ligand gated ion channel, 1
PDCD1 programmed cell death 1
PDE1C phosphodiesterase 1C, calmodulin-dependent 70kDa
PRKACG protein kinase, cAMP-dependent, catalytic, gamma
PRPF18 pre-mRNA processing factor 18
PRSS53 protease, serine, 53
PTK2B protein tyrosine kinase 2 beta
RAC2 ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)
RARG retinoic acid receptor, gamma
RNASE1 ribonuclease, RNase A family, 1 (pancreatic)
SCGB1A1 secretoglobin, family 1A, member 1 (uteroglobin)
SH3BP2 SH3-domain binding protein 2
SLC17A7 solute carrier family 17 (vesicular glutamate transporter), member 7
SLC25A4 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 4
SNTG1 syntrophin, gamma 1
SP100 SP100 nuclear antigen
SPN sialophorin
SPRY2 sprouty homolog 2 (Drosophila)
SRSF1 serine/arginine-rich splicing factor 1
SSTR4 somatostatin receptor 4
SULT1B1 sulfotransferase family, cytosolic, 1B, member 1
TCF7 transcription factor 7 (T-cell specific, HMG-box)
TCHH trichohyalin
TCP10 t-complex 10
TLN2 talin 2
TNFRSF21 tumor necrosis factor receptor superfamily, member 21
TNXB tenascin XB
TP63 tumor protein p63
TTN titin
TTR transthyretin
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor
WDR19 WD repeat domain 19
ZSCAN26 zinc finger and SCAN domain containing 26

decreased expression

Symbol Name
ALOX5AP arachidonate 5-lipoxygenase-activating protein
ANKFY1 ankyrin repeat and FYVE domain containing 1
ANKZF1 ankyrin repeat and zinc finger domain containing 1
ARHGEF10L Rho guanine nucleotide exchange factor (GEF) 10-like
ARRB2 arrestin, beta 2
ASAP1 ArfGAP with SH3 domain, ankyrin repeat and PH domain 1
ASAP1-IT1 ASAP1 intronic transcript 1
B3GAT3 beta-1,3-glucuronyltransferase 3
C14ORF79 chromosome 14 open reading frame 79
CCDC85C coiled-coil domain containing 85C
CCS copper chaperone for superoxide dismutase
CD101 CD101 molecule
CD8A CD8a molecule
CDK5RAP2 CDK5 regulatory subunit associated protein 2
CEP192 centrosomal protein 192kDa
CFD complement factor D (adipsin)
CHAF1B chromatin assembly factor 1, subunit B (p60)
CHRM4 cholinergic receptor, muscarinic 4
CLDN15 claudin 15
COBL cordon-bleu WH2 repeat protein
COL4A5 collagen, type IV, alpha 5
COPS7B COP9 signalosome subunit 7B
CST8 cystatin 8 (cystatin-related epididymal specific)
DCP1A decapping mRNA 1A
DGKD diacylglycerol kinase, delta 130kDa
DHDDS dehydrodolichyl diphosphate synthase
DHRS7B dehydrogenase/reductase (SDR family) member 7B
DHX38 DEAH (Asp-Glu-Ala-His) box polypeptide 38
DIXDC1 DIX domain containing 1
DLK2 delta-like 2 homolog (Drosophila)
DNAJB14 DnaJ (Hsp40) homolog, subfamily B, member 14
DOC2B double C2-like domains, beta
ECE2 endothelin converting enzyme 2
EPHA4 EPH receptor A4
EPN1 epsin 1
ERCC4 excision repair cross-complementation group 4
FANCF Fanconi anemia, complementation group F
FBXO31 F-box protein 31
FOXC1 forkhead box C1
FSD1 fibronectin type III and SPRY domain containing 1
GAB2 GRB2-associated binding protein 2
GNAI2 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2
GNL1 guanine nucleotide binding protein-like 1
GPATCH1 G patch domain containing 1
GUSBP3 glucuronidase, beta pseudogene 3
HIST1H3G histone cluster 1, H3g
IKZF5 IKAROS family zinc finger 5 (Pegasus)
IL15RA interleukin 15 receptor, alpha
IL19 interleukin 19
JOSD1 Josephin domain containing 1
KLHL28 kelch-like family member 28
KLHL3 kelch-like family member 3
LINC00652 long intergenic non-protein coding RNA 652
MAGOHB mago-nashi homolog B (Drosophila)
MED9 mediator complex subunit 9
METTL2B methyltransferase like 2B
MT1HL1 metallothionein 1H-like 1
MT1X metallothionein 1X
MVD mevalonate (diphospho) decarboxylase
NLRX1 NLR family member X1
NRGN neurogranin (protein kinase C substrate, RC3)
NRSN2 neurensin 2
OAS3 2'-5'-oligoadenylate synthetase 3, 100kDa
OR7A17 olfactory receptor, family 7, subfamily A, member 17
PDZK1IP1 PDZK1 interacting protein 1
PER3 period circadian clock 3
PHF21A PHD finger protein 21A
PIGR polymeric immunoglobulin receptor
PIN1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1
PLD2 phospholipase D2
POLA2 polymerase (DNA directed), alpha 2, accessory subunit
POMT2 protein-O-mannosyltransferase 2
PTTG3P pituitary tumor-transforming 3, pseudogene
QTRT1 queuine tRNA-ribosyltransferase 1
QTRTD1 queuine tRNA-ribosyltransferase domain containing 1
RGL1 ral guanine nucleotide dissociation stimulator-like 1
RIN1 Ras and Rab interactor 1
RNF39 ring finger protein 39
SIL1 SIL1 nucleotide exchange factor
SLC2A6 solute carrier family 2 (facilitated glucose transporter), member 6
SNORA21 small nucleolar RNA, H/ACA box 21
SNX6 sorting nexin 6
STAC SH3 and cysteine rich domain
SUSD4 sushi domain containing 4
SUZ12P1 suppressor of zeste 12 homolog pseudogene 1
TCEA2 transcription elongation factor A (SII), 2
TCP11 t-complex 11, testis-specific
THEG theg spermatid protein
THOC1 THO complex 1
TRAF2 TNF receptor-associated factor 2
TSPYL2 TSPY-like 2
UBIAD1 UbiA prenyltransferase domain containing 1
UNC93B1 unc-93 homolog B1 (C. elegans)
XRCC1 X-ray repair complementing defective repair in Chinese hamster cells 1
ZFR2 zinc finger RNA binding protein 2
ZFYVE16 zinc finger, FYVE domain containing 16
ZNF286A zinc finger protein 286A
ZNF574 zinc finger protein 574