| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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193 genes differentially expressed following the tetrahydroalstonine-2748 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| APBA2 | amyloid beta (A4) precursor protein-binding, family A, member 2 |
| ARTN | artemin |
| ATP6V0A2 | ATPase, H+ transporting, lysosomal V0 subunit a2 |
| BUB1 | BUB1 mitotic checkpoint serine/threonine kinase |
| C10ORF12 | chromosome 10 open reading frame 12 |
| C1ORF56 | chromosome 1 open reading frame 56 |
| CACNA1D | calcium channel, voltage-dependent, L type, alpha 1D subunit |
| CASP2 | caspase 2, apoptosis-related cysteine peptidase |
| CCDC71 | coiled-coil domain containing 71 |
| CD34 | CD34 molecule |
| CDC42EP1 | CDC42 effector protein (Rho GTPase binding) 1 |
| CDH6 | cadherin 6, type 2, K-cadherin (fetal kidney) |
| COL1A1 | collagen, type I, alpha 1 |
| COL5A1 | collagen, type V, alpha 1 |
| CTNS | cystinosin, lysosomal cystine transporter |
| CYP1A1 | cytochrome P450, family 1, subfamily A, polypeptide 1 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 |
| DDIT4 | DNA-damage-inducible transcript 4 |
| DLX2 | distal-less homeobox 2 |
| DNM1 | dynamin 1 |
| DOK2 | docking protein 2, 56kDa |
| EDNRB | endothelin receptor type B |
| ETAA1 | Ewing tumor-associated antigen 1 |
| ETV7 | ets variant 7 |
| FAM49B | family with sequence similarity 49, member B |
| GIT1 | G protein-coupled receptor kinase interacting ArfGAP 1 |
| GLS | glutaminase |
| GMPR | guanosine monophosphate reductase |
| GRPR | gastrin-releasing peptide receptor |
| GSN | gelsolin |
| HCRP1 | hepatocellular carcinoma-related HCRP1 |
| HDAC5 | histone deacetylase 5 |
| HECW1 | HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1 |
| HLA-DQB1 | major histocompatibility complex, class II, DQ beta 1 |
| HOMER3 | homer scaffolding protein 3 |
| IFI6 | interferon, alpha-inducible protein 6 |
| IGHM | immunoglobulin heavy constant mu |
| IL1B | interleukin 1, beta |
| INHBE | inhibin, beta E |
| ITGA2B | integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41) |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 |
| JADE2 | jade family PHD finger 2 |
| KCTD17 | potassium channel tetramerization domain containing 17 |
| KIAA1107 | KIAA1107 |
| LMCD1 | LIM and cysteine-rich domains 1 |
| LRRC14 | leucine rich repeat containing 14 |
| MAP4 | microtubule-associated protein 4 |
| MEGF6 | multiple EGF-like-domains 6 |
| MLANA | melan-A |
| MMP11 | matrix metallopeptidase 11 |
| MYL10 | myosin, light chain 10, regulatory |
| MYL4 | myosin, light chain 4, alkali; atrial, embryonic |
| NLRX1 | NLR family member X1 |
| OR7E156P | olfactory receptor, family 7, subfamily E, member 156 pseudogene |
| OTUD4 | OTU deubiquitinase 4 |
| PALM | paralemmin |
| PGBD5 | piggyBac transposable element derived 5 |
| PLEKHF1 | pleckstrin homology domain containing, family F (with FYVE domain) member 1 |
| PPFIA3 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 3 |
| PPP1R9A | protein phosphatase 1, regulatory subunit 9A |
| PVT1 | Pvt1 oncogene (non-protein coding) |
| RECK | reversion-inducing-cysteine-rich protein with kazal motifs |
| RHBG | Rh family, B glycoprotein (gene/pseudogene) |
| RND1 | Rho family GTPase 1 |
| RPS6KA2 | ribosomal protein S6 kinase, 90kDa, polypeptide 2 |
| SAG | S-antigen; retina and pineal gland (arrestin) |
| SH3BP2 | SH3-domain binding protein 2 |
| SIT1 | signaling threshold regulating transmembrane adaptor 1 |
| SLC1A4 | solute carrier family 1 (glutamate/neutral amino acid transporter), member 4 |
| SLC24A3 | solute carrier family 24 (sodium/potassium/calcium exchanger), member 3 |
| SLC25A44 | solute carrier family 25, member 44 |
| SLPI | secretory leukocyte peptidase inhibitor |
| SNW1 | SNW domain containing 1 |
| SNX13 | sorting nexin 13 |
| SPOCK3 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3 |
| STC1 | stanniocalcin 1 |
| STON1 | stonin 1 |
| TEX15 | testis expressed 15 |
| TNFRSF11A | tumor necrosis factor receptor superfamily, member 11a, NFKB activator |
| UBE3A | ubiquitin protein ligase E3A |
| USB1 | U6 snRNA biogenesis 1 |
| VAMP1 | vesicle-associated membrane protein 1 (synaptobrevin 1) |
| VAMP2 | vesicle-associated membrane protein 2 (synaptobrevin 2) |
| VDR | vitamin D (1,25- dihydroxyvitamin D3) receptor |
| VIPR2 | vasoactive intestinal peptide receptor 2 |
| WNT16 | wingless-type MMTV integration site family, member 16 |
| YIPF2 | Yip1 domain family, member 2 |
| ZCCHC14 | zinc finger, CCHC domain containing 14 |
| ZCCHC24 | zinc finger, CCHC domain containing 24 |
| ZDHHC14 | zinc finger, DHHC-type containing 14 |
| ZER1 | zyg-11 related, cell cycle regulator |
| ZNF134 | zinc finger protein 134 |
| ZNF37BP | zinc finger protein 37B, pseudogene |
| ZNF446 | zinc finger protein 446 |
| ZNF639 | zinc finger protein 639 |
| ZNF747 | zinc finger protein 747 |
| Symbol | Name |
|---|---|
| ACTL8 | actin-like 8 |
| ADM | adrenomedullin |
| AEN | apoptosis enhancing nuclease |
| AHDC1 | AT hook, DNA binding motif, containing 1 |
| ALPK1 | alpha-kinase 1 |
| ARRB1 | arrestin, beta 1 |
| C11ORF30 | chromosome 11 open reading frame 30 |
| C4ORF29 | chromosome 4 open reading frame 29 |
| C7ORF43 | chromosome 7 open reading frame 43 |
| CCNO | cyclin O |
| CHKB | choline kinase beta |
| CHPF | chondroitin polymerizing factor |
| CLSPN | claspin |
| CNR2 | cannabinoid receptor 2 (macrophage) |
| COQ6 | coenzyme Q6 monooxygenase |
| CRY2 | cryptochrome circadian clock 2 |
| CYP20A1 | cytochrome P450, family 20, subfamily A, polypeptide 1 |
| DFFB | DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase) |
| DNAL4 | dynein, axonemal, light chain 4 |
| EEF2KMT | eukaryotic elongation factor 2 lysine methyltransferase |
| ENTPD7 | ectonucleoside triphosphate diphosphohydrolase 7 |
| EPB41L5 | erythrocyte membrane protein band 4.1 like 5 |
| EPHA2 | EPH receptor A2 |
| EPHX2 | epoxide hydrolase 2, cytoplasmic |
| ERCC4 | excision repair cross-complementation group 4 |
| ERN2 | endoplasmic reticulum to nucleus signaling 2 |
| ERO1L | ERO1-like (S. cerevisiae) |
| FAM212B | family with sequence similarity 212, member B |
| FBRS | fibrosin |
| FGGY | FGGY carbohydrate kinase domain containing |
| FKBP5 | FK506 binding protein 5 |
| GABRB2 | gamma-aminobutyric acid (GABA) A receptor, beta 2 |
| GINS4 | GINS complex subunit 4 (Sld5 homolog) |
| GLS2 | glutaminase 2 (liver, mitochondrial) |
| GNE | glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase |
| GNG7 | guanine nucleotide binding protein (G protein), gamma 7 |
| GTF2H3 | general transcription factor IIH, polypeptide 3, 34kDa |
| HAUS2 | HAUS augmin-like complex, subunit 2 |
| HIRA | histone cell cycle regulator |
| HIST1H1D | histone cluster 1, H1d |
| HMOX1 | heme oxygenase 1 |
| HPS6 | Hermansky-Pudlak syndrome 6 |
| IFNAR1 | interferon (alpha, beta and omega) receptor 1 |
| IL22 | interleukin 22 |
| IQCG | IQ motif containing G |
| ITGA5 | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) |
| ITPKB | inositol-trisphosphate 3-kinase B |
| KCNF1 | potassium channel, voltage gated modifier subfamily F, member 1 |
| KIAA0894 | KIAA0894 protein |
| LSM14B | LSM14B, SCD6 homolog B (S. cerevisiae) |
| LYPD1 | LY6/PLAUR domain containing 1 |
| LYRM9 | LYR motif containing 9 |
| MAGI1 | membrane associated guanylate kinase, WW and PDZ domain containing 1 |
| MAMLD1 | mastermind-like domain containing 1 |
| MT1H | metallothionein 1H |
| NCALD | neurocalcin delta |
| NEAT1 | nuclear paraspeckle assembly transcript 1 (non-protein coding) |
| NIPAL2 | NIPA-like domain containing 2 |
| NPFFR1 | neuropeptide FF receptor 1 |
| NRGN | neurogranin (protein kinase C substrate, RC3) |
| ONECUT2 | one cut homeobox 2 |
| PACS1 | phosphofurin acidic cluster sorting protein 1 |
| PARP16 | poly (ADP-ribose) polymerase family, member 16 |
| PCDHA6 | protocadherin alpha 6 |
| PLCB3 | phospholipase C, beta 3 (phosphatidylinositol-specific) |
| PLEKHA6 | pleckstrin homology domain containing, family A member 6 |
| PLEKHB1 | pleckstrin homology domain containing, family B (evectins) member 1 |
| PLEKHO2 | pleckstrin homology domain containing, family O member 2 |
| POLR3D | polymerase (RNA) III (DNA directed) polypeptide D, 44kDa |
| RALGPS2 | Ral GEF with PH domain and SH3 binding motif 2 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 |
| ROM1 | retinal outer segment membrane protein 1 |
| RPUSD2 | RNA pseudouridylate synthase domain containing 2 |
| SCAI | suppressor of cancer cell invasion |
| SGTA | small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha |
| SLC35C1 | solute carrier family 35 (GDP-fucose transporter), member C1 |
| SMAD7 | SMAD family member 7 |
| SPRYD7 | SPRY domain containing 7 |
| ST6GALNAC2 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 |
| SUZ12P1 | suppressor of zeste 12 homolog pseudogene 1 |
| TAF5L | TAF5-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa |
| TCTA | T-cell leukemia translocation altered |
| TMEM121 | transmembrane protein 121 |
| TNFSF13 | tumor necrosis factor (ligand) superfamily, member 13 |
| TNKS2 | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2 |
| TRAF2 | TNF receptor-associated factor 2 |
| TRIM25 | tripartite motif containing 25 |
| TRPV1 | transient receptor potential cation channel, subfamily V, member 1 |
| UBQLN4 | ubiquilin 4 |
| UNC119 | unc-119 homolog (C. elegans) |
| VASH2 | vasohibin 2 |
| VCPIP1 | valosin containing protein (p97)/p47 complex interacting protein 1 |
| VEZT | vezatin, adherens junctions transmembrane protein |
| XRCC2 | X-ray repair complementing defective repair in Chinese hamster cells 2 |
| ZKSCAN3 | zinc finger with KRAB and SCAN domains 3 |
| ZNF652 | zinc finger protein 652 |
| ZNF862 | zinc finger protein 862 |
