tetrahydroalstonine-5728 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the tetrahydroalstonine-5728 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCG1 ATP-binding cassette, sub-family G (WHITE), member 1
ACAN aggrecan
ADGRG1 adhesion G protein-coupled receptor G1
ADIPOQ adiponectin, C1Q and collagen domain containing
AFF4 AF4/FMR2 family, member 4
AHNAK AHNAK nucleoprotein
AKT3 v-akt murine thymoma viral oncogene homolog 3
ALOX5AP arachidonate 5-lipoxygenase-activating protein
ANGPTL4 angiopoietin-like 4
ARL2BP ADP-ribosylation factor-like 2 binding protein
ARTN artemin
ATAD5 ATPase family, AAA domain containing 5
ATP8A2 ATPase, aminophospholipid transporter, class I, type 8A, member 2
ATP9B ATPase, class II, type 9B
BAIAP3 BAI1-associated protein 3
BCL2 B-cell CLL/lymphoma 2
BRF1 BRF1, RNA polymerase III transcription initiation factor 90 kDa subunit
C1QTNF9B-AS1 C1QTNF9B antisense RNA 1
CD34 CD34 molecule
CD68 CD68 molecule
CDC25C cell division cycle 25C
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2)
CENPJ centromere protein J
CLCN7 chloride channel, voltage-sensitive 7
CNN1 calponin 1, basic, smooth muscle
CNPY4 canopy FGF signaling regulator 4
CORO1A coronin, actin binding protein, 1A
CPT1A carnitine palmitoyltransferase 1A (liver)
CPZ carboxypeptidase Z
CRMP1 collapsin response mediator protein 1
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
CYP2A6 cytochrome P450, family 2, subfamily A, polypeptide 6
DLC1 DLC1 Rho GTPase activating protein
DMBT1 deleted in malignant brain tumors 1
DPY19L1P1 DPY19L1 pseudogene 1
EED embryonic ectoderm development
FAM50B family with sequence similarity 50, member B
FGF18 fibroblast growth factor 18
FGFR1 fibroblast growth factor receptor 1
GABBR1 gamma-aminobutyric acid (GABA) B receptor, 1
GABRA2 gamma-aminobutyric acid (GABA) A receptor, alpha 2
GGA1 golgi-associated, gamma adaptin ear containing, ARF binding protein 1
GNPTAB N-acetylglucosamine-1-phosphate transferase, alpha and beta subunits
GPR25 G protein-coupled receptor 25
GRIK5 glutamate receptor, ionotropic, kainate 5
GRIN1 glutamate receptor, ionotropic, N-methyl D-aspartate 1
GSK3A glycogen synthase kinase 3 alpha
HEMK1 HemK methyltransferase family member 1
HOXA11 homeobox A11
HTR1F 5-hydroxytryptamine (serotonin) receptor 1F, G protein-coupled
IDI2-AS1 IDI2 antisense RNA 1
IMPG2 interphotoreceptor matrix proteoglycan 2
KIAA0930 KIAA0930
KRT34 keratin 34, type I
LIME1 Lck interacting transmembrane adaptor 1
MAGIX MAGI family member, X-linked
MLLT3 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3
MTMR8 myotubularin related protein 8
NDUFA5 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 5
NF1 neurofibromin 1
NFIB nuclear factor I/B
NPIPB3 nuclear pore complex interacting protein family, member B3
NR6A1 nuclear receptor subfamily 6, group A, member 1
OSGIN2 oxidative stress induced growth inhibitor family member 2
PAFAH2 platelet-activating factor acetylhydrolase 2, 40kDa
PASK PAS domain containing serine/threonine kinase
PCK1 phosphoenolpyruvate carboxykinase 1 (soluble)
PF4 platelet factor 4
PIGQ phosphatidylinositol glycan anchor biosynthesis, class Q
POU5F1B POU class 5 homeobox 1B
PPP5C protein phosphatase 5, catalytic subunit
PRDX2 peroxiredoxin 2
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta
PRKCE protein kinase C, epsilon
PTGDS prostaglandin D2 synthase 21kDa (brain)
PYY peptide YY
RERE arginine-glutamic acid dipeptide (RE) repeats
RETN resistin
RGS5 regulator of G-protein signaling 5
RNF39 ring finger protein 39
RPRM reprimo, TP53 dependent G2 arrest mediator candidate
SARM1 sterile alpha and TIR motif containing 1
SMAD7 SMAD family member 7
SMC1A structural maintenance of chromosomes 1A
SNX13 sorting nexin 13
ST3GAL4 ST3 beta-galactoside alpha-2,3-sialyltransferase 4
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5
TAB1 TGF-beta activated kinase 1/MAP3K7 binding protein 1
TBC1D8 TBC1 domain family, member 8 (with GRAM domain)
TJP3 tight junction protein 3
TLN2 talin 2
TMOD3 tropomodulin 3 (ubiquitous)
TNFAIP6 tumor necrosis factor, alpha-induced protein 6
TRPC4 transient receptor potential cation channel, subfamily C, member 4
UPK3B uroplakin 3B
ZFP36L1 ZFP36 ring finger protein-like 1
ZNF37BP zinc finger protein 37B, pseudogene
ZNF749 zinc finger protein 749
ZSCAN18 zinc finger and SCAN domain containing 18
ZSCAN32 zinc finger and SCAN domain containing 32

decreased expression

Symbol Name
AGPAT4 1-acylglycerol-3-phosphate O-acyltransferase 4
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial)
ALPK1 alpha-kinase 1
AMT aminomethyltransferase
APOLD1 apolipoprotein L domain containing 1
ASPSCR1 alveolar soft part sarcoma chromosome region, candidate 1
BTC betacellulin
C16ORF45 chromosome 16 open reading frame 45
C8ORF60 chromosome 8 open reading frame 60
CA11 carbonic anhydrase XI
CABYR calcium binding tyrosine-(Y)-phosphorylation regulated
CAPN5 calpain 5
CARD8 caspase recruitment domain family, member 8
CDKN2D cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)
CLDN11 claudin 11
CLUHP3 clustered mitochondria (cluA/CLU1) homolog pseudogene 3
CPEB1 cytoplasmic polyadenylation element binding protein 1
CRY2 cryptochrome circadian clock 2
CRYBA2 crystallin, beta A2
CYP17A1 cytochrome P450, family 17, subfamily A, polypeptide 1
CYP26B1 cytochrome P450, family 26, subfamily B, polypeptide 1
CYP2B7P cytochrome P450, family 2, subfamily B, polypeptide 7, pseudogene
CYP2R1 cytochrome P450, family 2, subfamily R, polypeptide 1
CYP39A1 cytochrome P450, family 39, subfamily A, polypeptide 1
DDN dendrin
DPF3 D4, zinc and double PHD fingers, family 3
EAF2 ELL associated factor 2
ECM1 extracellular matrix protein 1
EFNA3 ephrin-A3
EHMT1 euchromatic histone-lysine N-methyltransferase 1
ERN2 endoplasmic reticulum to nucleus signaling 2
FGL1 fibrinogen-like 1
GAL3ST4 galactose-3-O-sulfotransferase 4
GLTSCR1 glioma tumor suppressor candidate region gene 1
GPR3 G protein-coupled receptor 3
GTF2H2B general transcription factor IIH, polypeptide 2B (pseudogene)
GTPBP6 GTP binding protein 6 (putative)
HIST3H2A histone cluster 3, H2a
HOXA4 homeobox A4
HOXA7 homeobox A7
HOXC8 homeobox C8
IFI6 interferon, alpha-inducible protein 6
IFNA14 interferon, alpha 14
IFT54 intraflagellar transport 54
IL17RB interleukin 17 receptor B
KCTD13 potassium channel tetramerization domain containing 13
KCTD17 potassium channel tetramerization domain containing 17
KIAA0232 KIAA0232
KRT31 keratin 31, type I
KRT75 keratin 75, type II
LOC257152 uncharacterized LOC257152
LRRC6 leucine rich repeat containing 6
MAP6D1 MAP6 domain containing 1
MRAS muscle RAS oncogene homolog
MTRF1 mitochondrial translational release factor 1
MYO1D myosin ID
NAG18 NAG18 mRNA
NDE1 nudE neurodevelopment protein 1
NDP Norrie disease (pseudoglioma)
NFKBIL1 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1
ODF2 outer dense fiber of sperm tails 2
PALMD palmdelphin
PCSK7 proprotein convertase subtilisin/kexin type 7
PITPNM1 phosphatidylinositol transfer protein, membrane-associated 1
PLCG2 phospholipase C, gamma 2 (phosphatidylinositol-specific)
PLEKHF1 pleckstrin homology domain containing, family F (with FYVE domain) member 1
PPP1R3C protein phosphatase 1, regulatory subunit 3C
PRAMEF11 PRAME family member 11
RAB3IL1 RAB3A interacting protein (rabin3)-like 1
RANBP17 RAN binding protein 17
RARRES3 retinoic acid receptor responder (tazarotene induced) 3
RBM42 RNA binding motif protein 42
RGP1 RGP1 retrograde golgi transport homolog (S. cerevisiae)
RNF122 ring finger protein 122
RNF2 ring finger protein 2
RUNX1-IT1 RUNX1 intronic transcript 1
SCUBE3 signal peptide, CUB domain, EGF-like 3
SERTAD3 SERTA domain containing 3
SGTA small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha
SH3BGR SH3 domain binding glutamate-rich protein
SIRT6 sirtuin 6
STEAP4 STEAP family member 4
SULT1A2 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 2
SULT4A1 sulfotransferase family 4A, member 1
SUZ12P1 suppressor of zeste 12 homolog pseudogene 1
TIMM50 translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae)
TNS2 tensin 2
TRIM45 tripartite motif containing 45
TRMT2A tRNA methyltransferase 2 homolog A (S. cerevisiae)
TRPM4 transient receptor potential cation channel, subfamily M, member 4
ZFHX2 zinc finger homeobox 2
ZFHX3 zinc finger homeobox 3
ZNF137P zinc finger protein 137, pseudogene
ZNF230 zinc finger protein 230
ZNF276 zinc finger protein 276
ZNF331 zinc finger protein 331
ZNF671 zinc finger protein 671
ZNF768 zinc finger protein 768