tetrahydrobiopterin biosynthetic process Gene Set

Dataset	GO Biological Process Annotations 2015
Category	structural or functional annotations
Type	biological process
Description	The chemical reactions and pathways resulting in the formation of tetrahydrobiopterin, the reduced form of biopterin (2-amino-4-hydroxy-6-(1,2-dihydroxypropyl)-pteridine). It functions as a hydroxylation coenzyme, e.g. in the conversion of phenylalanine to tyrosine. (Gene Ontology, GO_0006729)
External Link	http://amigo.geneontology.org/amigo/term/GO:0006729
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Genes

6 genes participating in the tetrahydrobiopterin biosynthetic process biological process from the curated GO Biological Process Annotations 2015 dataset.

Symbol	Name
GCH1	GTP cyclohydrolase 1
PCBD1	pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha
PCBD2	pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha (TCF1) 2
PTS	6-pyruvoyltetrahydropterin synthase
QDPR	quinoid dihydropteridine reductase
SPR	sepiapterin reductase (7,8-dihydrobiopterin:NADP+ oxidoreductase)