tetrahydrofolate biosynthetic process Gene Set

Dataset GO Biological Process Annotations 2025
Category structural or functional annotations
Type biological process
Description The chemical reactions and pathways resulting in the formation of tetrahydrofolate, 5,6,7,8-tetrahydrofolic acid, a folate derivative bearing additional hydrogens on the pterin group. (Gene Ontology, GO_0046654)
External Link http://amigo.geneontology.org/amigo/term/GO:0046654
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Genes

4 genes participating in the tetrahydrofolate biosynthetic process biological process from the curated GO Biological Process Annotations 2025 dataset.

Symbol Name
DHFR dihydrofolate reductase
DHFR2 dihydrofolate reductase 2
MTHFD1 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1, methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase
MTHFD1L methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like