tetrahydrofolate interconversion Gene Set

Dataset	GO Biological Process Annotations 2025
Category	structural or functional annotations
Type	biological process
Description	The chemical reactions and pathways by which one-carbon (C1) units are transferred between tetrahydrofolate molecules, to synthesise other tetrahydrofolate molecules. (Gene Ontology, GO_0035999)
External Link	http://amigo.geneontology.org/amigo/term/GO:0035999
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Genes

7 genes participating in the tetrahydrofolate interconversion biological process from the curated GO Biological Process Annotations 2025 dataset.

Symbol	Name
MTHFD1	methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1, methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase
MTHFD2	methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase
MTHFD2L	methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2-like
MTHFR	methylenetetrahydrofolate reductase (NAD(P)H)
SHMT1	serine hydroxymethyltransferase 1 (soluble)
ST20-MTHFS	ST20-MTHFS readthrough
TYMS	thymidylate synthetase