tetrahydrofolate metabolic process Gene Set

Dataset GO Biological Process Annotations
Category structural or functional annotations
Type biological process
Description The chemical reactions and pathways involving tetrahydrofolate, 5,6,7,8-tetrahydrofolic acid, a folate derivative bearing additional hydrogens on the pterin group. (Gene Ontology, GO_0046653)
External Link http://amigo.geneontology.org/amigo/term/GO:0046653
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Genes

17 genes participating in the tetrahydrofolate metabolic process biological process from the curated GO Biological Process Annotations dataset.

Symbol Name
ALDH1L1 aldehyde dehydrogenase 1 family, member L1
ALDH1L2 aldehyde dehydrogenase 1 family, member L2
ATIC 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase
DHFR dihydrofolate reductase
DHFRL1 dihydrofolate reductase-like 1
FTCD formimidoyltransferase cyclodeaminase
GART phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase
GCH1 GTP cyclohydrolase 1
MTHFD1 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1, methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase
MTHFD1L methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like
MTHFD2 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase
MTHFD2L methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2-like
MTHFR methylenetetrahydrofolate reductase (NAD(P)H)
PIPOX pipecolic acid oxidase
SHMT1 serine hydroxymethyltransferase 1 (soluble)
SHMT2 serine hydroxymethyltransferase 2 (mitochondrial)
TYMS thymidylate synthetase
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