tetramisole-2489 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

199 genes differentially expressed following the tetramisole-2489 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
A2M alpha-2-macroglobulin
ADGRB1 adhesion G protein-coupled receptor B1
ALDH1A3 aldehyde dehydrogenase 1 family, member A3
ATP9A ATPase, class II, type 9A
BCL2 B-cell CLL/lymphoma 2
C2ORF54 chromosome 2 open reading frame 54
C6ORF10 chromosome 6 open reading frame 10
CASP10 caspase 10, apoptosis-related cysteine peptidase
CCND2 cyclin D2
CDRT1 CMT1A duplicated region transcript 1
CFLAR CASP8 and FADD-like apoptosis regulator
CIB2 calcium and integrin binding family member 2
CLEC4M C-type lectin domain family 4, member M
CNTNAP1 contactin associated protein 1
COL10A1 collagen, type X, alpha 1
COL6A1 collagen, type VI, alpha 1
CYLC1 cylicin, basic protein of sperm head cytoskeleton 1
DEFA4 defensin, alpha 4, corticostatin
DHX34 DEAH (Asp-Glu-Ala-His) box polypeptide 34
DUSP4 dual specificity phosphatase 4
EFR3B EFR3 homolog B (S. cerevisiae)
EML2 echinoderm microtubule associated protein like 2
ENPEP glutamyl aminopeptidase (aminopeptidase A)
ESRP2 epithelial splicing regulatory protein 2
FCAR Fc fragment of IgA receptor
FGF5 fibroblast growth factor 5
GAB1 GRB2-associated binding protein 1
GLI3 GLI family zinc finger 3
GOLGA2P5 golgin A2 pseudogene 5
GP5 glycoprotein V (platelet)
GPRIN2 G protein regulated inducer of neurite outgrowth 2
GRHL2 grainyhead-like 2 (Drosophila)
GZMK granzyme K (granzyme 3; tryptase II)
H2AFX H2A histone family, member X
HDAC11 histone deacetylase 11
HECW1 HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1
HFE hemochromatosis
HIST1H2AM histone cluster 1, H2am
HIST1H4D histone cluster 1, H4d
HMG20B high mobility group 20B
IFNA17 interferon, alpha 17
IL5RA interleukin 5 receptor, alpha
ING2 inhibitor of growth family, member 2
IRF2BP1 interferon regulatory factor 2 binding protein 1
IRF4 interferon regulatory factor 4
ITGA10 integrin, alpha 10
ITIH2 inter-alpha-trypsin inhibitor heavy chain 2
KCNJ5 potassium channel, inwardly rectifying subfamily J, member 5
KIF1C kinesin family member 1C
KIF3A kinesin family member 3A
KLF3 Kruppel-like factor 3 (basic)
KLK13 kallikrein-related peptidase 13
LMO1 LIM domain only 1 (rhombotin 1)
LRAT lecithin retinol acyltransferase (phosphatidylcholine--retinol O-acyltransferase)
LRRC15 leucine rich repeat containing 15
LRRC31 leucine rich repeat containing 31
LTBP1 latent transforming growth factor beta binding protein 1
LTBP2 latent transforming growth factor beta binding protein 2
MAP4 microtubule-associated protein 4
MPP2 membrane protein, palmitoylated 2 (MAGUK p55 subfamily member 2)
MXD4 MAX dimerization protein 4
MYO1E myosin IE
MYOZ3 myozenin 3
NEUROD4 neuronal differentiation 4
NFKB2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
NRP2 neuropilin 2
NUP188 nucleoporin 188kDa
NXPH4 neurexophilin 4
OMG oligodendrocyte myelin glycoprotein
PAX5 paired box 5
PDPR pyruvate dehydrogenase phosphatase regulatory subunit
PLCG1 phospholipase C, gamma 1
PRPH peripherin
RAB6B RAB6B, member RAS oncogene family
RARRES3 retinoic acid receptor responder (tazarotene induced) 3
RASGRP2 RAS guanyl releasing protein 2 (calcium and DAG-regulated)
RUFY3 RUN and FYVE domain containing 3
SDHB succinate dehydrogenase complex, subunit B, iron sulfur (Ip)
SEC61A2 Sec61 alpha 2 subunit (S. cerevisiae)
SEMA6B sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6B
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SLC22A5 solute carrier family 22 (organic cation/carnitine transporter), member 5
SLC35E2 solute carrier family 35, member E2
SLC6A13 solute carrier family 6 (neurotransmitter transporter), member 13
SLC6A2 solute carrier family 6 (neurotransmitter transporter), member 2
SMAD3 SMAD family member 3
SNAPC5 small nuclear RNA activating complex, polypeptide 5, 19kDa
SP4 Sp4 transcription factor
SPON1 spondin 1, extracellular matrix protein
SPTBN1 spectrin, beta, non-erythrocytic 1
SRC SRC proto-oncogene, non-receptor tyrosine kinase
TBCD tubulin folding cofactor D
TCAF1 TRPM8 channel-associated factor 1
TMEM140 transmembrane protein 140
TSPAN9 tetraspanin 9
TTLL7 tubulin tyrosine ligase-like family member 7
USP18 ubiquitin specific peptidase 18
VPS45 vacuolar protein sorting 45 homolog (S. cerevisiae)
VSNL1 visinin-like 1

decreased expression

Symbol Name
ABCA7 ATP-binding cassette, sub-family A (ABC1), member 7
ABHD17B abhydrolase domain containing 17B
ABHD4 abhydrolase domain containing 4
ACOX2 acyl-CoA oxidase 2, branched chain
ACP6 acid phosphatase 6, lysophosphatidic
ACTR3B ARP3 actin-related protein 3 homolog B (yeast)
AMDHD2 amidohydrolase domain containing 2
APOBEC2 apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 2
ART1 ADP-ribosyltransferase 1
ASAP1 ArfGAP with SH3 domain, ankyrin repeat and PH domain 1
ASTE1 asteroid homolog 1 (Drosophila)
ATG2B autophagy related 2B
BPI bactericidal/permeability-increasing protein
C16ORF59 chromosome 16 open reading frame 59
C1QTNF3 C1q and tumor necrosis factor related protein 3
CA11 carbonic anhydrase XI
CAPN1 calpain 1, (mu/I) large subunit
CCL4 chemokine (C-C motif) ligand 4
CD48 CD48 molecule
CD70 CD70 molecule
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CLIP2 CAP-GLY domain containing linker protein 2
CNTLN centlein, centrosomal protein
CNTN1 contactin 1
DEF8 differentially expressed in FDCP 8 homolog (mouse)
DNM3 dynamin 3
DOK5 docking protein 5
DTX4 deltex 4, E3 ubiquitin ligase
DUSP2 dual specificity phosphatase 2
ELP5 elongator acetyltransferase complex subunit 5
ENTPD7 ectonucleoside triphosphate diphosphohydrolase 7
ERCC8 excision repair cross-complementation group 8
ERO1LB ERO1-like beta (S. cerevisiae)
EXD3 exonuclease 3'-5' domain containing 3
FBP1 fructose-1,6-bisphosphatase 1
FBXO31 F-box protein 31
FMOD fibromodulin
GLTSCR1 glioma tumor suppressor candidate region gene 1
GNB1L guanine nucleotide binding protein (G protein), beta polypeptide 1-like
GPR19 G protein-coupled receptor 19
GRIP2 glutamate receptor interacting protein 2
GSTCD glutathione S-transferase, C-terminal domain containing
HYAL2 hyaluronoglucosaminidase 2
IGF2BP2 insulin-like growth factor 2 mRNA binding protein 2
IL11RA interleukin 11 receptor, alpha
INCENP inner centromere protein antigens 135/155kDa
KCNMB3 potassium channel subfamily M regulatory beta subunit 3
LATS1 large tumor suppressor kinase 1
LHFP lipoma HMGIC fusion partner
LSM14B LSM14B, SCD6 homolog B (S. cerevisiae)
LTC4S leukotriene C4 synthase
LY6G6C lymphocyte antigen 6 complex, locus G6C
MC1R melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor)
MINOS1P1 mitochondrial inner membrane organizing system 1 pseudogene 1
MIR22HG MIR22 host gene
MKL2 MKL/myocardin-like 2
MTRF1 mitochondrial translational release factor 1
MUL1 mitochondrial E3 ubiquitin protein ligase 1
NAGPA N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase
NDE1 nudE neurodevelopment protein 1
NLRX1 NLR family member X1
NSUN3 NOP2/Sun domain family, member 3
PENK proenkephalin
PGP phosphoglycolate phosphatase
PHC1 polyhomeotic homolog 1 (Drosophila)
PIPOX pipecolic acid oxidase
PITPNM1 phosphatidylinositol transfer protein, membrane-associated 1
PLA2G12A phospholipase A2, group XIIA
PLCD1 phospholipase C, delta 1
PMFBP1 polyamine modulated factor 1 binding protein 1
PRSS53 protease, serine, 53
RAB33A RAB33A, member RAS oncogene family
RAPGEFL1 Rap guanine nucleotide exchange factor (GEF)-like 1
RECQL4 RecQ protein-like 4
RHBDF2 rhomboid 5 homolog 2 (Drosophila)
RNF122 ring finger protein 122
RNF19A ring finger protein 19A, RBR E3 ubiquitin protein ligase
RWDD2A RWD domain containing 2A
SENP7 SUMO1/sentrin specific peptidase 7
SGCG sarcoglycan, gamma (35kDa dystrophin-associated glycoprotein)
SHARPIN SHANK-associated RH domain interactor
SLC25A23 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23
SLITRK5 SLIT and NTRK-like family, member 5
SMPD2 sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase)
ST8SIA4 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4
SUOX sulfite oxidase
SYNC syncoilin, intermediate filament protein
TLR8 toll-like receptor 8
TMEM110 transmembrane protein 110
TNFRSF10D tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain
TNFRSF12A tumor necrosis factor receptor superfamily, member 12A
TNFSF13 tumor necrosis factor (ligand) superfamily, member 13
TRABD TraB domain containing
TRAIP TRAF interacting protein
TRANK1 tetratricopeptide repeat and ankyrin repeat containing 1
TRIM25 tripartite motif containing 25
URGCP upregulator of cell proliferation
XAB2 XPA binding protein 2
ZNF250 zinc finger protein 250
ZSCAN5A zinc finger and SCAN domain containing 5A