| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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197 genes differentially expressed following the tetrandrine-5821 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ACBD4 | acyl-CoA binding domain containing 4 |
| ACOT11 | acyl-CoA thioesterase 11 |
| ALDH4A1 | aldehyde dehydrogenase 4 family, member A1 |
| AMFR | autocrine motility factor receptor, E3 ubiquitin protein ligase |
| ARNTL | aryl hydrocarbon receptor nuclear translocator-like |
| B3GNT3 | UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3 |
| C1R | complement component 1, r subcomponent |
| C8ORF60 | chromosome 8 open reading frame 60 |
| CCNG2 | cyclin G2 |
| CD79B | CD79b molecule, immunoglobulin-associated beta |
| CDC42 | cell division cycle 42 |
| CRYBB2P1 | crystallin, beta B2 pseudogene 1 |
| CTH | cystathionine gamma-lyase |
| DNAJB9 | DnaJ (Hsp40) homolog, subfamily B, member 9 |
| EFHC2 | EF-hand domain (C-terminal) containing 2 |
| ETAA1 | Ewing tumor-associated antigen 1 |
| FAM13A | family with sequence similarity 13, member A |
| FBN1 | fibrillin 1 |
| FBXO38 | F-box protein 38 |
| FDFT1 | farnesyl-diphosphate farnesyltransferase 1 |
| FGFBP1 | fibroblast growth factor binding protein 1 |
| FLJ11292 | |
| GABARAPL1 | GABA(A) receptor-associated protein like 1 |
| GGA2 | golgi-associated, gamma adaptin ear containing, ARF binding protein 2 |
| GLG1 | golgi glycoprotein 1 |
| GM2A | GM2 ganglioside activator |
| GPR176 | G protein-coupled receptor 176 |
| GREB1L | growth regulation by estrogen in breast cancer-like |
| GTPBP4 | GTP binding protein 4 |
| HIRA | histone cell cycle regulator |
| HMGCR | 3-hydroxy-3-methylglutaryl-CoA reductase |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) |
| HMOX1 | heme oxygenase 1 |
| IDI1 | isopentenyl-diphosphate delta isomerase 1 |
| IFI6 | interferon, alpha-inducible protein 6 |
| IFT122 | intraflagellar transport 122 |
| IL1RN | interleukin 1 receptor antagonist |
| INSIG1 | insulin induced gene 1 |
| IQSEC2 | IQ motif and Sec7 domain 2 |
| ISG20 | interferon stimulated exonuclease gene 20kDa |
| LDLR | low density lipoprotein receptor |
| LGR5 | leucine-rich repeat containing G protein-coupled receptor 5 |
| LIPG | lipase, endothelial |
| LMAN1 | lectin, mannose-binding, 1 |
| MLLT4 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4 |
| MON1B | MON1 secretory trafficking family member B |
| MRPS11 | mitochondrial ribosomal protein S11 |
| MSMO1 | methylsterol monooxygenase 1 |
| MST1 | macrophage stimulating 1 |
| MT1M | metallothionein 1M |
| MTAP | methylthioadenosine phosphorylase |
| MTM1 | myotubularin 1 |
| NAT6 | N-acetyltransferase 6 (GCN5-related) |
| NDRG1 | N-myc downstream regulated 1 |
| NEBL | nebulette |
| NGLY1 | N-glycanase 1 |
| NPC1 | Niemann-Pick disease, type C1 |
| NRN1 | neuritin 1 |
| OAS2 | 2'-5'-oligoadenylate synthetase 2, 69/71kDa |
| OVGP1 | oviductal glycoprotein 1, 120kDa |
| PASK | PAS domain containing serine/threonine kinase |
| PBOV1 | prostate and breast cancer overexpressed 1 |
| PHACTR2 | phosphatase and actin regulator 2 |
| PIGZ | phosphatidylinositol glycan anchor biosynthesis, class Z |
| PIP5K1A | phosphatidylinositol-4-phosphate 5-kinase, type I, alpha |
| PLEK | pleckstrin |
| PVT1 | Pvt1 oncogene (non-protein coding) |
| RAD23B | RAD23 homolog B (S. cerevisiae) |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) |
| SLC17A5 | solute carrier family 17 (acidic sugar transporter), member 5 |
| SLC22A14 | solute carrier family 22, member 14 |
| SLC22A18 | solute carrier family 22, member 18 |
| SLC43A3 | solute carrier family 43, member 3 |
| SMAD5 | SMAD family member 5 |
| SMC1A | structural maintenance of chromosomes 1A |
| SQLE | squalene epoxidase |
| SSH3 | slingshot protein phosphatase 3 |
| ST3GAL5 | ST3 beta-galactoside alpha-2,3-sialyltransferase 5 |
| STC1 | stanniocalcin 1 |
| STK3 | serine/threonine kinase 3 |
| SUGCT | succinyl-CoA:glutarate-CoA transferase |
| SUSD5 | sushi domain containing 5 |
| SYT1 | synaptotagmin I |
| TAGLN3 | transgelin 3 |
| TBC1D9B | TBC1 domain family, member 9B (with GRAM domain) |
| TBL2 | transducin (beta)-like 2 |
| TENM1 | teneurin transmembrane protein 1 |
| TLDC1 | TBC/LysM-associated domain containing 1 |
| TMEM183A | transmembrane protein 183A |
| TMEM19 | transmembrane protein 19 |
| TNC | tenascin C |
| TRD | T cell receptor delta locus |
| TSFM | Ts translation elongation factor, mitochondrial |
| TSKU | tsukushi, small leucine rich proteoglycan |
| TSPAN1 | tetraspanin 1 |
| UTRN | utrophin |
| VAMP2 | vesicle-associated membrane protein 2 (synaptobrevin 2) |
| WSB1 | WD repeat and SOCS box containing 1 |
| ZNF407 | zinc finger protein 407 |
| Symbol | Name |
|---|---|
| ADGRG2 | adhesion G protein-coupled receptor G2 |
| AKR1B1 | aldo-keto reductase family 1, member B1 (aldose reductase) |
| ALPK1 | alpha-kinase 1 |
| ASS1 | argininosuccinate synthase 1 |
| ATP13A2 | ATPase type 13A2 |
| BATF3 | basic leucine zipper transcription factor, ATF-like 3 |
| BCCIP | BRCA2 and CDKN1A interacting protein |
| C16ORF59 | chromosome 16 open reading frame 59 |
| CBY1 | chibby homolog 1 (Drosophila) |
| CCNE1 | cyclin E1 |
| CDADC1 | cytidine and dCMP deaminase domain containing 1 |
| CDC37L1 | cell division cycle 37-like 1 |
| CDKL3 | cyclin-dependent kinase-like 3 |
| CEP131 | centrosomal protein 131kDa |
| COBL | cordon-bleu WH2 repeat protein |
| CPEB1 | cytoplasmic polyadenylation element binding protein 1 |
| CRIP2 | cysteine-rich protein 2 |
| CRYL1 | crystallin, lambda 1 |
| CYP17A1 | cytochrome P450, family 17, subfamily A, polypeptide 1 |
| CYP2J2 | cytochrome P450, family 2, subfamily J, polypeptide 2 |
| DHX57 | DEAH (Asp-Glu-Ala-Asp/His) box polypeptide 57 |
| DNAJB2 | DnaJ (Hsp40) homolog, subfamily B, member 2 |
| ELOVL4 | ELOVL fatty acid elongase 4 |
| ENTPD5 | ectonucleoside triphosphate diphosphohydrolase 5 |
| ERCC2 | excision repair cross-complementation group 2 |
| ERN2 | endoplasmic reticulum to nucleus signaling 2 |
| FDXR | ferredoxin reductase |
| FOXK2 | forkhead box K2 |
| FURIN | furin (paired basic amino acid cleaving enzyme) |
| GLCE | glucuronic acid epimerase |
| GLDC | glycine dehydrogenase (decarboxylating) |
| GNAZ | guanine nucleotide binding protein (G protein), alpha z polypeptide |
| GRWD1 | glutamate-rich WD repeat containing 1 |
| HIST1H2AG | histone cluster 1, H2ag |
| HIST1H2BI | histone cluster 1, H2bi |
| HIST2H2BE | histone cluster 2, H2be |
| HYAL3 | hyaluronoglucosaminidase 3 |
| IL15RA | interleukin 15 receptor, alpha |
| IMPACT | impact RWD domain protein |
| ITGB2 | integrin, beta 2 (complement component 3 receptor 3 and 4 subunit) |
| ITPKB | inositol-trisphosphate 3-kinase B |
| JMJD4 | jumonji domain containing 4 |
| KCNN4 | potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4 |
| KDELC1 | KDEL (Lys-Asp-Glu-Leu) containing 1 |
| KDM5C | lysine (K)-specific demethylase 5C |
| KIAA1549L | KIAA1549-like |
| KLK5 | kallikrein-related peptidase 5 |
| LHPP | phospholysine phosphohistidine inorganic pyrophosphate phosphatase |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 |
| MED9 | mediator complex subunit 9 |
| MYL5 | myosin, light chain 5, regulatory |
| NARFL | nuclear prelamin A recognition factor-like |
| NDE1 | nudE neurodevelopment protein 1 |
| NHEJ1 | nonhomologous end-joining factor 1 |
| NR1H3 | nuclear receptor subfamily 1, group H, member 3 |
| NSD1 | nuclear receptor binding SET domain protein 1 |
| NT5E | 5'-nucleotidase, ecto (CD73) |
| OR7E156P | olfactory receptor, family 7, subfamily E, member 156 pseudogene |
| OR7E47P | olfactory receptor, family 7, subfamily E, member 47 pseudogene |
| PAQR6 | progestin and adipoQ receptor family member VI |
| PDE8B | phosphodiesterase 8B |
| PLCB3 | phospholipase C, beta 3 (phosphatidylinositol-specific) |
| PLCD1 | phospholipase C, delta 1 |
| PLK2 | polo-like kinase 2 |
| PMPCA | peptidase (mitochondrial processing) alpha |
| PRKAA2 | protein kinase, AMP-activated, alpha 2 catalytic subunit |
| PRR15L | proline rich 15-like |
| PTDSS2 | phosphatidylserine synthase 2 |
| PTGFR | prostaglandin F receptor (FP) |
| RAB8B | RAB8B, member RAS oncogene family |
| SCAMP5 | secretory carrier membrane protein 5 |
| SCN1B | sodium channel, voltage gated, type I beta subunit |
| SEC61A2 | Sec61 alpha 2 subunit (S. cerevisiae) |
| SECISBP2 | SECIS binding protein 2 |
| SERPINB2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 |
| SETBP1 | SET binding protein 1 |
| SH2B2 | SH2B adaptor protein 2 |
| SH3TC2 | SH3 domain and tetratricopeptide repeats 2 |
| SLC12A8 | solute carrier family 12, member 8 |
| SLC27A5 | solute carrier family 27 (fatty acid transporter), member 5 |
| SOX12 | SRY (sex determining region Y)-box 12 |
| STEAP4 | STEAP family member 4 |
| STK25 | serine/threonine kinase 25 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa |
| TMEM212 | transmembrane protein 212 |
| TMEM62 | transmembrane protein 62 |
| TMOD3 | tropomodulin 3 (ubiquitous) |
| TNK1 | tyrosine kinase, non-receptor, 1 |
| TRABD | TraB domain containing |
| TTBK2 | tau tubulin kinase 2 |
| UNKL | unkempt family zinc finger-like |
| USP27X | ubiquitin specific peptidase 27, X-linked |
| VPS4A | vacuolar protein sorting 4 homolog A (S. cerevisiae) |
| WDR41 | WD repeat domain 41 |
| ZDHHC14 | zinc finger, DHHC-type containing 14 |
| ZNF696 | zinc finger protein 696 |
| ZNF747 | zinc finger protein 747 |
| ZNHIT2 | zinc finger, HIT-type containing 2 |
