| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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197 genes differentially expressed following the tetrandrine-6082 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ACSL4 | acyl-CoA synthetase long-chain family member 4 |
| ACTN2 | actinin, alpha 2 |
| ADAMTS5 | ADAM metallopeptidase with thrombospondin type 1 motif, 5 |
| AFF2 | AF4/FMR2 family, member 2 |
| ARHGDIG | Rho GDP dissociation inhibitor (GDI) gamma |
| AVPR1B | arginine vasopressin receptor 1B |
| BEGAIN | brain-enriched guanylate kinase-associated |
| BHLHE40 | basic helix-loop-helix family, member e40 |
| BMP1 | bone morphogenetic protein 1 |
| C3 | complement component 3 |
| CADM4 | cell adhesion molecule 4 |
| CAMSAP1 | calmodulin regulated spectrin-associated protein 1 |
| CCNG2 | cyclin G2 |
| CD1A | CD1a molecule |
| CD200 | CD200 molecule |
| CDK6 | cyclin-dependent kinase 6 |
| CDY1 | chromodomain protein, Y-linked, 1 |
| CLCN6 | chloride channel, voltage-sensitive 6 |
| COL10A1 | collagen, type X, alpha 1 |
| CPED1 | cadherin-like and PC-esterase domain containing 1 |
| CPQ | carboxypeptidase Q |
| CYP2A7 | cytochrome P450, family 2, subfamily A, polypeptide 7 |
| DDIT4 | DNA-damage-inducible transcript 4 |
| DES | desmin |
| DGKQ | diacylglycerol kinase, theta 110kDa |
| DMBT1 | deleted in malignant brain tumors 1 |
| DVL3 | dishevelled segment polarity protein 3 |
| EGF | epidermal growth factor |
| ELAVL2 | ELAV like neuron-specific RNA binding protein 2 |
| FAM117A | family with sequence similarity 117, member A |
| FAM212B | family with sequence similarity 212, member B |
| FBN1 | fibrillin 1 |
| FGF22 | fibroblast growth factor 22 |
| FOXO4 | forkhead box O4 |
| GBP2 | guanylate binding protein 2, interferon-inducible |
| GLT8D2 | glycosyltransferase 8 domain containing 2 |
| GM2A | GM2 ganglioside activator |
| GPR135 | G protein-coupled receptor 135 |
| GRK5 | G protein-coupled receptor kinase 5 |
| GRM2 | glutamate receptor, metabotropic 2 |
| GSAP | gamma-secretase activating protein |
| HDAC6 | histone deacetylase 6 |
| HLA-DPA1 | major histocompatibility complex, class II, DP alpha 1 |
| HMGCR | 3-hydroxy-3-methylglutaryl-CoA reductase |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) |
| HOXA10 | homeobox A10 |
| HOXA7 | homeobox A7 |
| HPGD | hydroxyprostaglandin dehydrogenase 15-(NAD) |
| IDI1 | isopentenyl-diphosphate delta isomerase 1 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 |
| IL21R | interleukin 21 receptor |
| INSIG1 | insulin induced gene 1 |
| ISG20 | interferon stimulated exonuclease gene 20kDa |
| KDR | kinase insert domain receptor |
| KIF21B | kinesin family member 21B |
| KLHL24 | kelch-like family member 24 |
| LAMP1 | lysosomal-associated membrane protein 1 |
| LPIN1 | lipin 1 |
| MAFF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F |
| MED25 | mediator complex subunit 25 |
| MRPL41 | mitochondrial ribosomal protein L41 |
| MSMO1 | methylsterol monooxygenase 1 |
| MST1 | macrophage stimulating 1 |
| MT1F | metallothionein 1F |
| MVD | mevalonate (diphospho) decarboxylase |
| NPPA | natriuretic peptide A |
| NRG1 | neuregulin 1 |
| NUPR1 | nuclear protein, transcriptional regulator, 1 |
| P2RX1 | purinergic receptor P2X, ligand gated ion channel, 1 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 |
| PLA2G2A | phospholipase A2, group IIA (platelets, synovial fluid) |
| PLA2G3 | phospholipase A2, group III |
| PMS2P3 | postmeiotic segregation increased 2 pseudogene 3 |
| SERHL2 | serine hydrolase-like 2 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 |
| SLC11A1 | solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1 |
| SLC16A5 | solute carrier family 16 (monocarboxylate transporter), member 5 |
| SLC1A4 | solute carrier family 1 (glutamate/neutral amino acid transporter), member 4 |
| SLCO4C1 | solute carrier organic anion transporter family, member 4C1 |
| SQLE | squalene epoxidase |
| STAC | SH3 and cysteine rich domain |
| SYN3 | synapsin III |
| TAGLN3 | transgelin 3 |
| TAZ | tafazzin |
| TBX1 | T-box 1 |
| TLDC1 | TBC/LysM-associated domain containing 1 |
| TLR2 | toll-like receptor 2 |
| TNFSF9 | tumor necrosis factor (ligand) superfamily, member 9 |
| TOR4A | torsin family 4, member A |
| TP63 | tumor protein p63 |
| TRD | T cell receptor delta locus |
| TTC38 | tetratricopeptide repeat domain 38 |
| TUBA4B | tubulin, alpha 4b |
| USP22 | ubiquitin specific peptidase 22 |
| XIAP | X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase |
| XYLB | xylulokinase homolog (H. influenzae) |
| ZBED4 | zinc finger, BED-type containing 4 |
| ZNF442 | zinc finger protein 442 |
| ZRSR1 | zinc finger (CCCH type), RNA-binding motif and serine/arginine rich 1 |
| Symbol | Name |
|---|---|
| ACTG2 | actin, gamma 2, smooth muscle, enteric |
| ALKBH4 | alkB, alkylation repair homolog 4 (E. coli) |
| ALOX12P2 | arachidonate 12-lipoxygenase pseudogene 2 |
| ANP32A-IT1 | ANP32A intronic transcript 1 |
| AP1S1 | adaptor-related protein complex 1, sigma 1 subunit |
| AP3M2 | adaptor-related protein complex 3, mu 2 subunit |
| APBB3 | amyloid beta (A4) precursor protein-binding, family B, member 3 |
| ARHGEF1 | Rho guanine nucleotide exchange factor (GEF) 1 |
| ARMC4 | armadillo repeat containing 4 |
| ASB7 | ankyrin repeat and SOCS box containing 7 |
| ASPHD1 | aspartate beta-hydroxylase domain containing 1 |
| ATP8B2 | ATPase, aminophospholipid transporter, class I, type 8B, member 2 |
| BAHD1 | bromo adjacent homology domain containing 1 |
| BCL9 | B-cell CLL/lymphoma 9 |
| BFSP1 | beaded filament structural protein 1, filensin |
| C2ORF54 | chromosome 2 open reading frame 54 |
| C5AR2 | complement component 5a receptor 2 |
| C9ORF40 | chromosome 9 open reading frame 40 |
| CAPN15 | calpain 15 |
| CBL | Cbl proto-oncogene, E3 ubiquitin protein ligase |
| CD82 | CD82 molecule |
| CEP85 | centrosomal protein 85kDa |
| CHKB | choline kinase beta |
| CNNM4 | cyclin and CBS domain divalent metal cation transport mediator 4 |
| CRIP1 | cysteine-rich protein 1 (intestinal) |
| CSF1R | colony stimulating factor 1 receptor |
| CYP1A1 | cytochrome P450, family 1, subfamily A, polypeptide 1 |
| DCP1A | decapping mRNA 1A |
| DYSF | dysferlin |
| ECHDC3 | enoyl CoA hydratase domain containing 3 |
| EHMT1 | euchromatic histone-lysine N-methyltransferase 1 |
| EPHB3 | EPH receptor B3 |
| FAN1 | FANCD2/FANCI-associated nuclease 1 |
| FBXO22 | F-box protein 22 |
| FCHSD2 | FCH and double SH3 domains 2 |
| FGFR4 | fibroblast growth factor receptor 4 |
| GLS2 | glutaminase 2 (liver, mitochondrial) |
| GMPR | guanosine monophosphate reductase |
| GPR27 | G protein-coupled receptor 27 |
| GUSBP3 | glucuronidase, beta pseudogene 3 |
| HIRA | histone cell cycle regulator |
| HIST1H2AL | histone cluster 1, H2al |
| IDI2-AS1 | IDI2 antisense RNA 1 |
| IFNAR1 | interferon (alpha, beta and omega) receptor 1 |
| IPO8 | importin 8 |
| IQSEC2 | IQ motif and Sec7 domain 2 |
| KAT2A | K(lysine) acetyltransferase 2A |
| KDM8 | lysine (K)-specific demethylase 8 |
| KIAA0556 | KIAA0556 |
| KLC2 | kinesin light chain 2 |
| KPNA5 | karyopherin alpha 5 (importin alpha 6) |
| KRT13 | keratin 13, type I |
| LYRM9 | LYR motif containing 9 |
| MAST3 | microtubule associated serine/threonine kinase 3 |
| MCOLN3 | mucolipin 3 |
| MVP | major vault protein |
| NABP2 | nucleic acid binding protein 2 |
| NEUROD4 | neuronal differentiation 4 |
| NOD1 | nucleotide-binding oligomerization domain containing 1 |
| NRSN2 | neurensin 2 |
| OAS3 | 2'-5'-oligoadenylate synthetase 3, 100kDa |
| ONECUT2 | one cut homeobox 2 |
| PCSK7 | proprotein convertase subtilisin/kexin type 7 |
| PGBD5 | piggyBac transposable element derived 5 |
| PIGN | phosphatidylinositol glycan anchor biosynthesis, class N |
| PIGQ | phosphatidylinositol glycan anchor biosynthesis, class Q |
| PLCB3 | phospholipase C, beta 3 (phosphatidylinositol-specific) |
| PLEKHM2 | pleckstrin homology domain containing, family M (with RUN domain) member 2 |
| PLEKHO2 | pleckstrin homology domain containing, family O member 2 |
| PRPH | peripherin |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 |
| RAB40C | RAB40C, member RAS oncogene family |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 |
| RFXAP | regulatory factor X-associated protein |
| SDC3 | syndecan 3 |
| SIX1 | SIX homeobox 1 |
| SLC12A8 | solute carrier family 12, member 8 |
| SLC22A14 | solute carrier family 22, member 14 |
| SLC25A23 | solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23 |
| SLC44A1 | solute carrier family 44 (choline transporter), member 1 |
| SMAD7 | SMAD family member 7 |
| SMARCD3 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3 |
| SP140L | SP140 nuclear body protein-like |
| SUN2 | Sad1 and UNC84 domain containing 2 |
| TAB1 | TGF-beta activated kinase 1/MAP3K7 binding protein 1 |
| TGFB1I1 | transforming growth factor beta 1 induced transcript 1 |
| TIMM50 | translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae) |
| TMEM180 | transmembrane protein 180 |
| TRIM21 | tripartite motif containing 21 |
| WDR76 | WD repeat domain 76 |
| WLS | wntless Wnt ligand secretion mediator |
| ZBED1 | zinc finger, BED-type containing 1 |
| ZBTB39 | zinc finger and BTB domain containing 39 |
| ZC3H3 | zinc finger CCCH-type containing 3 |
| ZCCHC24 | zinc finger, CCHC domain containing 24 |
| ZNF286A | zinc finger protein 286A |
| ZNF428 | zinc finger protein 428 |
| ZNF804A | zinc finger protein 804A |
