| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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200 genes differentially expressed following the tetrandrine-7178 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ACSL1 | acyl-CoA synthetase long-chain family member 1 |
| ANKRD2 | ankyrin repeat domain 2 (stretch responsive muscle) |
| APC | adenomatous polyposis coli |
| APOBEC3B | apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3B |
| APOC1 | apolipoprotein C-I |
| ARMCX1 | armadillo repeat containing, X-linked 1 |
| ARTN | artemin |
| ATF3 | activating transcription factor 3 |
| BHLHE40 | basic helix-loop-helix family, member e40 |
| CBLB | Cbl proto-oncogene B, E3 ubiquitin protein ligase |
| CCNG2 | cyclin G2 |
| CCPG1 | cell cycle progression 1 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) |
| CDKL3 | cyclin-dependent kinase-like 3 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 |
| COQ7 | coenzyme Q7 homolog, ubiquinone (yeast) |
| CSE1L | CSE1 chromosome segregation 1-like (yeast) |
| CYP51A1 | cytochrome P450, family 51, subfamily A, polypeptide 1 |
| DDIT4 | DNA-damage-inducible transcript 4 |
| DDX58 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 58 |
| DNAJB4 | DnaJ (Hsp40) homolog, subfamily B, member 4 |
| DUSP10 | dual specificity phosphatase 10 |
| DUSP4 | dual specificity phosphatase 4 |
| EGR3 | early growth response 3 |
| EIF1AY | eukaryotic translation initiation factor 1A, Y-linked |
| FAAH | fatty acid amide hydrolase |
| FAM120C | family with sequence similarity 120C |
| FCMR | Fc fragment of IgM receptor |
| GBP1 | guanylate binding protein 1, interferon-inducible |
| GNE | glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase |
| HDAC5 | histone deacetylase 5 |
| HDGFRP3 | hepatoma-derived growth factor, related protein 3 |
| HFE | hemochromatosis |
| HMGCR | 3-hydroxy-3-methylglutaryl-CoA reductase |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) |
| HMOX1 | heme oxygenase 1 |
| HSD17B7 | hydroxysteroid (17-beta) dehydrogenase 7 |
| ICAM1 | intercellular adhesion molecule 1 |
| IDI1 | isopentenyl-diphosphate delta isomerase 1 |
| IFI6 | interferon, alpha-inducible protein 6 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 |
| INSIG1 | insulin induced gene 1 |
| ISG20 | interferon stimulated exonuclease gene 20kDa |
| JUND | jun D proto-oncogene |
| KATNB1 | katanin p80 (WD repeat containing) subunit B 1 |
| KLHL24 | kelch-like family member 24 |
| LDLR | low density lipoprotein receptor |
| LGALS8 | lectin, galactoside-binding, soluble, 8 |
| LOC100287590 | uncharacterized LOC100287590 |
| LPIN1 | lipin 1 |
| LTBP2 | latent transforming growth factor beta binding protein 2 |
| LZTFL1 | leucine zipper transcription factor-like 1 |
| MAFF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F |
| MAGI1 | membrane associated guanylate kinase, WW and PDZ domain containing 1 |
| ME1 | malic enzyme 1, NADP(+)-dependent, cytosolic |
| MET | MET proto-oncogene, receptor tyrosine kinase |
| MSMO1 | methylsterol monooxygenase 1 |
| MT1E | metallothionein 1E |
| MT1F | metallothionein 1F |
| MT1H | metallothionein 1H |
| MT1HL1 | metallothionein 1H-like 1 |
| MT1X | metallothionein 1X |
| MVD | mevalonate (diphospho) decarboxylase |
| NDE1 | nudE neurodevelopment protein 1 |
| NEAT1 | nuclear paraspeckle assembly transcript 1 (non-protein coding) |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) |
| NUPR1 | nuclear protein, transcriptional regulator, 1 |
| PDCD4 | programmed cell death 4 (neoplastic transformation inhibitor) |
| PRLR | prolactin receptor |
| PTBP3 | polypyrimidine tract binding protein 3 |
| RB1CC1 | RB1-inducible coiled-coil 1 |
| RCAN1 | regulator of calcineurin 1 |
| RHOQ | ras homolog family member Q |
| RNF19A | ring finger protein 19A, RBR E3 ubiquitin protein ligase |
| RNFT1 | ring finger protein, transmembrane 1 |
| RP2 | retinitis pigmentosa 2 (X-linked recessive) |
| RPS6KA5 | ribosomal protein S6 kinase, 90kDa, polypeptide 5 |
| RUSC2 | RUN and SH3 domain containing 2 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) |
| SFXN3 | sideroflexin 3 |
| SIK2 | salt-inducible kinase 2 |
| SLC17A5 | solute carrier family 17 (acidic sugar transporter), member 5 |
| SLC2A6 | solute carrier family 2 (facilitated glucose transporter), member 6 |
| SLCO4C1 | solute carrier organic anion transporter family, member 4C1 |
| SMEK1 | SMEK homolog 1, suppressor of mek1 (Dictyostelium) |
| SOS2 | son of sevenless homolog 2 (Drosophila) |
| SP100 | SP100 nuclear antigen |
| SQLE | squalene epoxidase |
| STX5 | syntaxin 5 |
| TAF1 | TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa |
| TFDP2 | transcription factor Dp-2 (E2F dimerization partner 2) |
| TIMM17A | translocase of inner mitochondrial membrane 17 homolog A (yeast) |
| TJP3 | tight junction protein 3 |
| TLE4 | transducin-like enhancer of split 4 |
| TLR2 | toll-like receptor 2 |
| TMEM97 | transmembrane protein 97 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 |
| TNFRSF9 | tumor necrosis factor receptor superfamily, member 9 |
| ZNF500 | zinc finger protein 500 |
| ZNF609 | zinc finger protein 609 |
| Symbol | Name |
|---|---|
| AGPAT3 | 1-acylglycerol-3-phosphate O-acyltransferase 3 |
| ALPK1 | alpha-kinase 1 |
| ANKZF1 | ankyrin repeat and zinc finger domain containing 1 |
| ARHGAP11A | Rho GTPase activating protein 11A |
| ARHGDIG | Rho GDP dissociation inhibitor (GDI) gamma |
| ARID3A | AT rich interactive domain 3A (BRIGHT-like) |
| ATAD5 | ATPase family, AAA domain containing 5 |
| ATP8B2 | ATPase, aminophospholipid transporter, class I, type 8B, member 2 |
| C11ORF95 | chromosome 11 open reading frame 95 |
| C19ORF40 | chromosome 19 open reading frame 40 |
| C1ORF115 | chromosome 1 open reading frame 115 |
| CCS | copper chaperone for superoxide dismutase |
| CHST8 | carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 8 |
| CIC | capicua transcriptional repressor |
| CLUH | clustered mitochondria (cluA/CLU1) homolog |
| CNPPD1 | cyclin Pas1/PHO80 domain containing 1 |
| CTNNBIP1 | catenin, beta interacting protein 1 |
| DCUN1D2 | DCN1, defective in cullin neddylation 1, domain containing 2 |
| DDX54 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 54 |
| DEAF1 | DEAF1 transcription factor |
| DHX30 | DEAH (Asp-Glu-Ala-His) box helicase 30 |
| EDC4 | enhancer of mRNA decapping 4 |
| EPB41L5 | erythrocyte membrane protein band 4.1 like 5 |
| ETAA1 | Ewing tumor-associated antigen 1 |
| EVPL | envoplakin |
| FAM53B | family with sequence similarity 53, member B |
| FBXW7 | F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase |
| FHOD1 | formin homology 2 domain containing 1 |
| FPGS | folylpolyglutamate synthase |
| FUZ | fuzzy planar cell polarity protein |
| FXN | frataxin |
| GABRA2 | gamma-aminobutyric acid (GABA) A receptor, alpha 2 |
| GAN | gigaxonin |
| GATAD2A | GATA zinc finger domain containing 2A |
| GPATCH3 | G patch domain containing 3 |
| GSTM2 | glutathione S-transferase mu 2 (muscle) |
| HIRA | histone cell cycle regulator |
| KAT2A | K(lysine) acetyltransferase 2A |
| KBTBD4 | kelch repeat and BTB (POZ) domain containing 4 |
| KCNN4 | potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4 |
| KCTD20 | potassium channel tetramerization domain containing 20 |
| KIAA0232 | KIAA0232 |
| KIAA0556 | KIAA0556 |
| KLHL26 | kelch-like family member 26 |
| LGALS3BP | lectin, galactoside-binding, soluble, 3 binding protein |
| LRP5 | low density lipoprotein receptor-related protein 5 |
| MAP1S | microtubule-associated protein 1S |
| MAPK12 | mitogen-activated protein kinase 12 |
| MISP | mitotic spindle positioning |
| MOSPD3 | motile sperm domain containing 3 |
| MRPL12 | mitochondrial ribosomal protein L12 |
| MTERF1 | mitochondrial transcription termination factor 1 |
| MUL1 | mitochondrial E3 ubiquitin protein ligase 1 |
| NBEAL2 | neurobeachin-like 2 |
| NCAM2 | neural cell adhesion molecule 2 |
| NOTCH1 | notch 1 |
| OGFRL1 | opioid growth factor receptor-like 1 |
| P3H1 | prolyl 3-hydroxylase 1 |
| PCDHB3 | protocadherin beta 3 |
| PECR | peroxisomal trans-2-enoyl-CoA reductase |
| PEX26 | peroxisomal biogenesis factor 26 |
| PHACTR4 | phosphatase and actin regulator 4 |
| PIN1 | peptidylprolyl cis/trans isomerase, NIMA-interacting 1 |
| PPP1R3C | protein phosphatase 1, regulatory subunit 3C |
| PRKX | protein kinase, X-linked |
| RAB3IL1 | RAB3A interacting protein (rabin3)-like 1 |
| RECQL4 | RecQ protein-like 4 |
| RFNG | RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase |
| RNF123 | ring finger protein 123 |
| RNF25 | ring finger protein 25 |
| SARS2 | seryl-tRNA synthetase 2, mitochondrial |
| SCD5 | stearoyl-CoA desaturase 5 |
| SCHIP1 | schwannomin interacting protein 1 |
| SCN1B | sodium channel, voltage gated, type I beta subunit |
| SH2D4A | SH2 domain containing 4A |
| SLC25A22 | solute carrier family 25 (mitochondrial carrier: glutamate), member 22 |
| SLC2A8 | solute carrier family 2 (facilitated glucose transporter), member 8 |
| SNAPC4 | small nuclear RNA activating complex, polypeptide 4, 190kDa |
| SOX3 | SRY (sex determining region Y)-box 3 |
| TESK1 | testis-specific kinase 1 |
| TET3 | tet methylcytosine dioxygenase 3 |
| TGFBRAP1 | transforming growth factor, beta receptor associated protein 1 |
| THAP4 | THAP domain containing 4 |
| THOP1 | thimet oligopeptidase 1 |
| THRAP3 | thyroid hormone receptor associated protein 3 |
| TMEM104 | transmembrane protein 104 |
| TNK1 | tyrosine kinase, non-receptor, 1 |
| TRAF2 | TNF receptor-associated factor 2 |
| TRMT2A | tRNA methyltransferase 2 homolog A (S. cerevisiae) |
| UNC13B | unc-13 homolog B (C. elegans) |
| USP36 | ubiquitin specific peptidase 36 |
| VAV1 | vav 1 guanine nucleotide exchange factor |
| VGF | VGF nerve growth factor inducible |
| XAB2 | XPA binding protein 2 |
| XKR8 | XK, Kell blood group complex subunit-related family, member 8 |
| XRCC3 | X-ray repair complementing defective repair in Chinese hamster cells 3 |
| YEATS2 | YEATS domain containing 2 |
| ZBTB25 | zinc finger and BTB domain containing 25 |
| ZDHHC18 | zinc finger, DHHC-type containing 18 |
| ZNF35 | zinc finger protein 35 |
