A pre-organized unit composed either of adhesion molecules (mainly integrins and members of the Ig superfamily), signaling receptors and/or enzyme-enriched plasma membrane domains that compartmentalizes cellular processes. Tetraspanin-enriched microdomains might be specially suited for the regulation of avidity of adhesion receptors and the compartmentalization of enzymatic activities. (Gene Ontology, GO_0097197)
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7 proteins localized to the tetraspanin-enriched microdomain cellular component from the COMPARTMENTS Curated Protein Localization Evidence Scores dataset.
