tetroquinone-3338 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the tetroquinone-3338 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCB6 ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group)
ACAP1 ArfGAP with coiled-coil, ankyrin repeat and PH domains 1
AFF2 AF4/FMR2 family, member 2
AHSP alpha hemoglobin stabilizing protein
AIRE autoimmune regulator
ALDH1L1 aldehyde dehydrogenase 1 family, member L1
ALDOB aldolase B, fructose-bisphosphate
APOC1 apolipoprotein C-I
AQP1 aquaporin 1 (Colton blood group)
ARPIN actin-related protein 2/3 complex inhibitor
ATP10B ATPase, class V, type 10B
ATP2A2 ATPase, Ca++ transporting, cardiac muscle, slow twitch 2
BTF3P11 basic transcription factor 3 pseudogene 11
C1ORF21 chromosome 1 open reading frame 21
C1QB complement component 1, q subcomponent, B chain
CASP10 caspase 10, apoptosis-related cysteine peptidase
CCDC181 coiled-coil domain containing 181
CCDC87 coiled-coil domain containing 87
CCL27 chemokine (C-C motif) ligand 27
CDA cytidine deaminase
CEACAM3 carcinoembryonic antigen-related cell adhesion molecule 3
CEP112 centrosomal protein 112kDa
CFHR2 complement factor H-related 2
CFHR4 complement factor H-related 4
CLCA1 chloride channel accessory 1
CNPY4 canopy FGF signaling regulator 4
CNR2 cannabinoid receptor 2 (macrophage)
COL14A1 collagen, type XIV, alpha 1
COLEC11 collectin sub-family member 11
CRKL v-crk avian sarcoma virus CT10 oncogene homolog-like
CTNS cystinosin, lysosomal cystine transporter
CXORF21 chromosome X open reading frame 21
CYTH4 cytohesin 4
DOK4 docking protein 4
DTNB dystrobrevin, beta
DTX3 deltex 3, E3 ubiquitin ligase
E2F5 E2F transcription factor 5, p130-binding
F5 coagulation factor V (proaccelerin, labile factor)
FGF5 fibroblast growth factor 5
FSHB follicle stimulating hormone, beta polypeptide
FST follistatin
FZR1 fizzy/cell division cycle 20 related 1 (Drosophila)
GGA3 golgi-associated, gamma adaptin ear containing, ARF binding protein 3
GPR3 G protein-coupled receptor 3
HAP1 huntingtin-associated protein 1
HPX hemopexin
HRH4 histamine receptor H4
IGKV4-1 immunoglobulin kappa variable 4-1
IL12RB1 interleukin 12 receptor, beta 1
IL1RAP interleukin 1 receptor accessory protein
IL5RA interleukin 5 receptor, alpha
ITGB4 integrin, beta 4
ITGB6 integrin, beta 6
KCNAB3 potassium channel, voltage gated subfamily A regulatory beta subunit 3
KERA keratocan
KHDRBS3 KH domain containing, RNA binding, signal transduction associated 3
KIAA1324 KIAA1324
KIF1C kinesin family member 1C
KLK2 kallikrein-related peptidase 2
KREMEN2 kringle containing transmembrane protein 2
LATS1 large tumor suppressor kinase 1
LRP12 low density lipoprotein receptor-related protein 12
LRRC48 leucine rich repeat containing 48
MUC5AC mucin 5AC, oligomeric mucus/gel-forming
NCF4 neutrophil cytosolic factor 4, 40kDa
NCR2 natural cytotoxicity triggering receptor 2
NEU3 sialidase 3 (membrane sialidase)
NR2F1 nuclear receptor subfamily 2, group F, member 1
OMG oligodendrocyte myelin glycoprotein
PCDHGA1 protocadherin gamma subfamily A, 1
PCSK6 proprotein convertase subtilisin/kexin type 6
PDE4DIP phosphodiesterase 4D interacting protein
PLEKHS1 pleckstrin homology domain containing, family S member 1
PON1 paraoxonase 1
PRKACG protein kinase, cAMP-dependent, catalytic, gamma
PVR poliovirus receptor
RBM12B RNA binding motif protein 12B
SAG S-antigen; retina and pineal gland (arrestin)
SDC2 syndecan 2
SLC17A4 solute carrier family 17, member 4
SLC1A4 solute carrier family 1 (glutamate/neutral amino acid transporter), member 4
SLC1A7 solute carrier family 1 (glutamate transporter), member 7
SLC7A2 solute carrier family 7 (cationic amino acid transporter, y+ system), member 2
SNTG1 syntrophin, gamma 1
SPOCK2 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2
SPON1 spondin 1, extracellular matrix protein
SPRR1B small proline-rich protein 1B
SSX1 synovial sarcoma, X breakpoint 1
STEAP4 STEAP family member 4
TAPBPL TAP binding protein-like
TAS2R10 taste receptor, type 2, member 10
TBX10 T-box 10
TJAP1 tight junction associated protein 1 (peripheral)
TRMT1 tRNA methyltransferase 1 homolog (S. cerevisiae)
TTR transthyretin
TUBA8 tubulin, alpha 8
VAMP1 vesicle-associated membrane protein 1 (synaptobrevin 1)
WDR78 WD repeat domain 78
WNT5A wingless-type MMTV integration site family, member 5A

decreased expression

Symbol Name
ABHD3 abhydrolase domain containing 3
ABT1 activator of basal transcription 1
ACADSB acyl-CoA dehydrogenase, short/branched chain
ADCY7 adenylate cyclase 7
AP1AR adaptor-related protein complex 1 associated regulatory protein
APBB3 amyloid beta (A4) precursor protein-binding, family B, member 3
ARHGEF26 Rho guanine nucleotide exchange factor (GEF) 26
BAGE B melanoma antigen
BCL11B B-cell CLL/lymphoma 11B (zinc finger protein)
BCL7A B-cell CLL/lymphoma 7A
C10ORF88 chromosome 10 open reading frame 88
C5ORF28 chromosome 5 open reading frame 28
CACNA1H calcium channel, voltage-dependent, T type, alpha 1H subunit
CCDC25 coiled-coil domain containing 25
CENPO centromere protein O
CGA glycoprotein hormones, alpha polypeptide
CHKB choline kinase beta
CLCN5 chloride channel, voltage-sensitive 5
CLEC16A C-type lectin domain family 16, member A
CXORF56 chromosome X open reading frame 56
CYP2R1 cytochrome P450, family 2, subfamily R, polypeptide 1
DFFB DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase)
DIXDC1 DIX domain containing 1
DNM1 dynamin 1
EEF2KMT eukaryotic elongation factor 2 lysine methyltransferase
EGFL7 EGF-like-domain, multiple 7
EHHADH enoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase
FAN1 FANCD2/FANCI-associated nuclease 1
FGD1 FYVE, RhoGEF and PH domain containing 1
FGD6 FYVE, RhoGEF and PH domain containing 6
FILIP1L filamin A interacting protein 1-like
FOXD1 forkhead box D1
GALK1 galactokinase 1
GLCE glucuronic acid epimerase
GMEB1 glucocorticoid modulatory element binding protein 1
GMIP GEM interacting protein
GPALPP1 GPALPP motifs containing 1
GTF3C3 general transcription factor IIIC, polypeptide 3, 102kDa
GUSBP3 glucuronidase, beta pseudogene 3
HOXC10 homeobox C10
HYI hydroxypyruvate isomerase (putative)
IGFLR1 IGF-like family receptor 1
IMPACT impact RWD domain protein
IRAK4 interleukin-1 receptor-associated kinase 4
JRKL JRK-like
KAT2A K(lysine) acetyltransferase 2A
LRP5L low density lipoprotein receptor-related protein 5-like
MANEA mannosidase, endo-alpha
MBTPS2 membrane-bound transcription factor peptidase, site 2
MNX1 motor neuron and pancreas homeobox 1
MUL1 mitochondrial E3 ubiquitin protein ligase 1
MUM1 melanoma associated antigen (mutated) 1
NDRG4 NDRG family member 4
NUBPL nucleotide binding protein-like
NUS1P3 nuclear undecaprenyl pyrophosphate synthase 1 homolog (S. cerevisiae) pseudogene 3
OTUB2 OTU deubiquitinase, ubiquitin aldehyde binding 2
PC pyruvate carboxylase
PCDHB8 protocadherin beta 8
PGP phosphoglycolate phosphatase
PLEKHM2 pleckstrin homology domain containing, family M (with RUN domain) member 2
POLE polymerase (DNA directed), epsilon, catalytic subunit
PRPF38B pre-mRNA processing factor 38B
PRRG2 proline rich Gla (G-carboxyglutamic acid) 2
RIN2 Ras and Rab interactor 2
RNASEL ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent)
RNF38 ring finger protein 38
RP2 retinitis pigmentosa 2 (X-linked recessive)
RPL23AP32 ribosomal protein L23a pseudogene 32
SCAI suppressor of cancer cell invasion
SERPINA5 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5
SGTA small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha
SKI SKI proto-oncogene
SLC26A2 solute carrier family 26 (anion exchanger), member 2
SLC8B1 solute carrier family 8 (sodium/lithium/calcium exchanger), member B1
SMEK2 SMEK homolog 2, suppressor of mek1 (Dictyostelium)
SND1-IT1 SND1 intronic transcript 1
SNIP1 Smad nuclear interacting protein 1
SOX12 SRY (sex determining region Y)-box 12
SPATA2L spermatogenesis associated 2-like
SPIDR scaffolding protein involved in DNA repair
SPRYD7 SPRY domain containing 7
SSFA2 sperm specific antigen 2
STARD13 StAR-related lipid transfer (START) domain containing 13
TANC2 tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2
THBS3 thrombospondin 3
TMEM183A transmembrane protein 183A
TRIM5 tripartite motif containing 5
TSPAN15 tetraspanin 15
UBXN8 UBX domain protein 8
VARS valyl-tRNA synthetase
XPNPEP3 X-prolyl aminopeptidase 3, mitochondrial
ZNF227 zinc finger protein 227
ZNF254 zinc finger protein 254
ZNF34 zinc finger protein 34
ZNF446 zinc finger protein 446
ZNF747 zinc finger protein 747
ZNF862 zinc finger protein 862
ZNHIT2 zinc finger, HIT-type containing 2