| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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197 genes differentially expressed following the tetroquinone-4159 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| A2M | alpha-2-macroglobulin |
| ABCB6 | ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group) |
| ABI2 | abl-interactor 2 |
| ACAA2 | acetyl-CoA acyltransferase 2 |
| AHSG | alpha-2-HS-glycoprotein |
| AIM2 | absent in melanoma 2 |
| AKR1C4 | aldo-keto reductase family 1, member C4 |
| ANKRD7 | ankyrin repeat domain 7 |
| APOL6 | apolipoprotein L, 6 |
| ARHGEF10 | Rho guanine nucleotide exchange factor (GEF) 10 |
| ARMCX4 | armadillo repeat containing, X-linked 4 |
| ARSD | arylsulfatase D |
| ATN1 | atrophin 1 |
| C14ORF1 | chromosome 14 open reading frame 1 |
| C2ORF68 | chromosome 2 open reading frame 68 |
| C5ORF42 | chromosome 5 open reading frame 42 |
| CDC14B | cell division cycle 14B |
| CFAP69 | cilia and flagella associated protein 69 |
| CHAT | choline O-acetyltransferase |
| CHRNB2 | cholinergic receptor, nicotinic, beta 2 (neuronal) |
| COL15A1 | collagen, type XV, alpha 1 |
| COL3A1 | collagen, type III, alpha 1 |
| CST8 | cystatin 8 (cystatin-related epididymal specific) |
| CXCL8 | chemokine (C-X-C motif) ligand 8 |
| CYP4F8 | cytochrome P450, family 4, subfamily F, polypeptide 8 |
| DGAT1 | diacylglycerol O-acyltransferase 1 |
| DGCR5 | DiGeorge syndrome critical region gene 5 (non-protein coding) |
| DNAI2 | dynein, axonemal, intermediate chain 2 |
| DNAJC28 | DnaJ (Hsp40) homolog, subfamily C, member 28 |
| DTX2 | deltex 2, E3 ubiquitin ligase |
| ELL2 | elongation factor, RNA polymerase II, 2 |
| ERG | v-ets avian erythroblastosis virus E26 oncogene homolog |
| FBXO40 | F-box protein 40 |
| FYN | FYN proto-oncogene, Src family tyrosine kinase |
| GBP1 | guanylate binding protein 1, interferon-inducible |
| GPC3 | glypican 3 |
| GRM8 | glutamate receptor, metabotropic 8 |
| GUCY1A2 | guanylate cyclase 1, soluble, alpha 2 |
| HR | hair growth associated |
| HRH2 | histamine receptor H2 |
| HSPA6 | heat shock 70kDa protein 6 (HSP70B') |
| IBSP | integrin-binding sialoprotein |
| ICA1 | islet cell autoantigen 1, 69kDa |
| IFNA14 | interferon, alpha 14 |
| IL36R | interleukin 36 receptor |
| IRF4 | interferon regulatory factor 4 |
| KALRN | kalirin, RhoGEF kinase |
| KCNC1 | potassium channel, voltage gated Shaw related subfamily C, member 1 |
| KCNJ5 | potassium channel, inwardly rectifying subfamily J, member 5 |
| KLHL25 | kelch-like family member 25 |
| LAMB4 | laminin, beta 4 |
| LRCH4 | leucine-rich repeats and calponin homology (CH) domain containing 4 |
| LRRTM2 | leucine rich repeat transmembrane neuronal 2 |
| LYL1 | lymphoblastic leukemia associated hematopoiesis regulator 1 |
| MAP4K2 | mitogen-activated protein kinase kinase kinase kinase 2 |
| MAPRE3 | microtubule-associated protein, RP/EB family, member 3 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 |
| MID1 | midline 1 |
| MTHFR | methylenetetrahydrofolate reductase (NAD(P)H) |
| NDUFA2 | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 2, 8kDa |
| NPR1 | natriuretic peptide receptor 1 |
| PAX8 | paired box 8 |
| PCNXL2 | pecanex-like 2 (Drosophila) |
| PILRA | paired immunoglobin-like type 2 receptor alpha |
| PKD2L2 | polycystic kidney disease 2-like 2 |
| POLL | polymerase (DNA directed), lambda |
| PSMB2 | proteasome (prosome, macropain) subunit, beta type, 2 |
| RABGAP1 | RAB GTPase activating protein 1 |
| RALGPS2 | Ral GEF with PH domain and SH3 binding motif 2 |
| RBMS2 | RNA binding motif, single stranded interacting protein 2 |
| RBPMS | RNA binding protein with multiple splicing |
| RNF125 | ring finger protein 125, E3 ubiquitin protein ligase |
| RUNX1 | runt-related transcription factor 1 |
| S100A7 | S100 calcium binding protein A7 |
| S100A8 | S100 calcium binding protein A8 |
| SAMD9 | sterile alpha motif domain containing 9 |
| SATB2 | SATB homeobox 2 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A |
| SERHL2 | serine hydrolase-like 2 |
| SLC22A7 | solute carrier family 22 (organic anion transporter), member 7 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 |
| SLC9A3R2 | solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 2 |
| SPATA6 | spermatogenesis associated 6 |
| SPN | sialophorin |
| SSX1 | synovial sarcoma, X breakpoint 1 |
| STS | steroid sulfatase (microsomal), isozyme S |
| SYNE1 | spectrin repeat containing, nuclear envelope 1 |
| SYT2 | synaptotagmin II |
| TM4SF1 | transmembrane 4 L six family member 1 |
| TMEM63A | transmembrane protein 63A |
| TONSL | tonsoku-like, DNA repair protein |
| TP53I11 | tumor protein p53 inducible protein 11 |
| VAV2 | vav 2 guanine nucleotide exchange factor |
| ZER1 | zyg-11 related, cell cycle regulator |
| ZMIZ2 | zinc finger, MIZ-type containing 2 |
| ZNF155 | zinc finger protein 155 |
| ZNF451 | zinc finger protein 451 |
| ZXDB | zinc finger, X-linked, duplicated B |
| Symbol | Name |
|---|---|
| ABCA7 | ATP-binding cassette, sub-family A (ABC1), member 7 |
| ACAD10 | acyl-CoA dehydrogenase family, member 10 |
| ADTRP | androgen-dependent TFPI-regulating protein |
| AGMAT | agmatine ureohydrolase (agmatinase) |
| ALOX12P2 | arachidonate 12-lipoxygenase pseudogene 2 |
| ANKH | ANKH inorganic pyrophosphate transport regulator |
| ANKRD36 | ankyrin repeat domain 36 |
| ANXA2P3 | annexin A2 pseudogene 3 |
| AP1S1 | adaptor-related protein complex 1, sigma 1 subunit |
| APH1A | APH1A gamma secretase subunit |
| ARHGAP4 | Rho GTPase activating protein 4 |
| ARHGEF17 | Rho guanine nucleotide exchange factor (GEF) 17 |
| ARID3B | AT rich interactive domain 3B (BRIGHT-like) |
| ATG16L1 | autophagy related 16-like 1 (S. cerevisiae) |
| ATP6V1B1 | ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B1 |
| B3GALT4 | UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 4 |
| BHLHE41 | basic helix-loop-helix family, member e41 |
| CACNA2D2 | calcium channel, voltage-dependent, alpha 2/delta subunit 2 |
| CALML5 | calmodulin-like 5 |
| CAMK1 | calcium/calmodulin-dependent protein kinase I |
| CBL | Cbl proto-oncogene, E3 ubiquitin protein ligase |
| CCNO | cyclin O |
| CCNT1 | cyclin T1 |
| CLGN | calmegin |
| CLUHP3 | clustered mitochondria (cluA/CLU1) homolog pseudogene 3 |
| CRY2 | cryptochrome circadian clock 2 |
| DDX54 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 54 |
| EPPK1 | epiplakin 1 |
| EPX | eosinophil peroxidase |
| FAM120C | family with sequence similarity 120C |
| FAM169A | family with sequence similarity 169, member A |
| FAM46C | family with sequence similarity 46, member C |
| FAM76A | family with sequence similarity 76, member A |
| FGD1 | FYVE, RhoGEF and PH domain containing 1 |
| FGF13 | fibroblast growth factor 13 |
| FGGY | FGGY carbohydrate kinase domain containing |
| FLJ22184 | |
| FRMD1 | FERM domain containing 1 |
| GBP2 | guanylate binding protein 2, interferon-inducible |
| GFI1 | growth factor independent 1 transcription repressor |
| GK3P | glycerol kinase 3 pseudogene |
| GLTSCR1 | glioma tumor suppressor candidate region gene 1 |
| GNG3 | guanine nucleotide binding protein (G protein), gamma 3 |
| HOXC8 | homeobox C8 |
| IFI6 | interferon, alpha-inducible protein 6 |
| ITIH2 | inter-alpha-trypsin inhibitor heavy chain 2 |
| KHDRBS3 | KH domain containing, RNA binding, signal transduction associated 3 |
| KIAA1024 | KIAA1024 |
| LOC729164 | hCG1732469 |
| LOC730101 | uncharacterized LOC730101 |
| LRRC37A2 | leucine rich repeat containing 37, member A2 |
| LY6G6C | lymphocyte antigen 6 complex, locus G6C |
| MAPK10 | mitogen-activated protein kinase 10 |
| MEFV | Mediterranean fever |
| METTL16 | methyltransferase like 16 |
| MRPS18C | mitochondrial ribosomal protein S18C |
| MTMR12 | myotubularin related protein 12 |
| NAT6 | N-acetyltransferase 6 (GCN5-related) |
| NDOR1 | NADPH dependent diflavin oxidoreductase 1 |
| NIPAL2 | NIPA-like domain containing 2 |
| NIPSNAP3B | nipsnap homolog 3B (C. elegans) |
| OR2B6 | olfactory receptor, family 2, subfamily B, member 6 |
| PADI1 | peptidyl arginine deiminase, type I |
| PARD6A | par-6 family cell polarity regulator alpha |
| PARG | poly (ADP-ribose) glycohydrolase |
| PHF14 | PHD finger protein 14 |
| PLEKHO2 | pleckstrin homology domain containing, family O member 2 |
| PPP2R3B | protein phosphatase 2, regulatory subunit B'', beta |
| PRAMEF11 | PRAME family member 11 |
| PSG4 | pregnancy specific beta-1-glycoprotein 4 |
| RHBG | Rh family, B glycoprotein (gene/pseudogene) |
| RNF122 | ring finger protein 122 |
| RNF2 | ring finger protein 2 |
| SCN1B | sodium channel, voltage gated, type I beta subunit |
| SH2D4A | SH2 domain containing 4A |
| SKI | SKI proto-oncogene |
| SLC22A18AS | solute carrier family 22 (organic cation transporter), member 18 antisense |
| SLC34A2 | solute carrier family 34 (type II sodium/phosphate cotransporter), member 2 |
| SLC44A1 | solute carrier family 44 (choline transporter), member 1 |
| SLC5A5 | solute carrier family 5 (sodium/iodide cotransporter), member 5 |
| SLIT2 | slit homolog 2 (Drosophila) |
| SLMO1 | slowmo homolog 1 (Drosophila) |
| SLPI | secretory leukocyte peptidase inhibitor |
| SMAD5 | SMAD family member 5 |
| SNCAIP | synuclein, alpha interacting protein |
| SYNC | syncoilin, intermediate filament protein |
| TAS2R10 | taste receptor, type 2, member 10 |
| TCN1 | transcobalamin I (vitamin B12 binding protein, R binder family) |
| TET3 | tet methylcytosine dioxygenase 3 |
| TRABD | TraB domain containing |
| TRAF2 | TNF receptor-associated factor 2 |
| TRIM36 | tripartite motif containing 36 |
| TRPM2 | transient receptor potential cation channel, subfamily M, member 2 |
| WDR33 | WD repeat domain 33 |
| WDR4 | WD repeat domain 4 |
| XRCC1 | X-ray repair complementing defective repair in Chinese hamster cells 1 |
| ZBTB44 | zinc finger and BTB domain containing 44 |
| ZDHHC14 | zinc finger, DHHC-type containing 14 |
| ZSWIM1 | zinc finger, SWIM-type containing 1 |
