tfap2a Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
Description transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)|The protein encoded by this gene is a transcription factor that binds the consensus sequence 5'-GCCNNNGGC-3'. The encoded protein functions as either a homodimer or as a heterodimer with similar family members. This protein activates the transcription of some genes while inhibiting the transcription of others. Defects in this gene are a cause of branchiooculofacial syndrome (BOFS). Three transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Dec 2009] (NCBI Entrez Gene Database, 7020)
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Genes

10 genes co-occuring with the biological term tfap2a in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
CGB chorionic gonadotropin, beta polypeptide
ETS1 v-ets avian erythroblastosis virus E26 oncogene homolog 1
IRF4 interferon regulatory factor 4
IRF6 interferon regulatory factor 6
NR2F2 nuclear receptor subfamily 2, group F, member 2
SMAD2 SMAD family member 2
SMAD3 SMAD family member 3
TFAP2A transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
TFAP2E transcription factor AP-2 epsilon (activating enhancer binding protein 2 epsilon)
TGFB1 transforming growth factor, beta 1