transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)|The protein encoded by this gene is a transcription factor that binds the consensus sequence 5'-GCCNNNGGC-3'. The encoded protein functions as either a homodimer or as a heterodimer with similar family members. This protein activates the transcription of some genes while inhibiting the transcription of others. Defects in this gene are a cause of branchiooculofacial syndrome (BOFS). Three transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Dec 2009] (NCBI Entrez Gene Database, 7020)
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10 genes co-occuring with the biological term tfap2a in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.