tgfbr1 Gene Set

Dataset	GeneRIF Biological Term Annotations
Category	structural or functional annotations
Type	biological term
Description	transforming growth factor, beta receptor 1\|The protein encoded by this gene forms a heteromeric complex with type II TGF-beta receptors when bound to TGF-beta, transducing the TGF-beta signal from the cell surface to the cytoplasm. The encoded protein is a serine/threonine protein kinase. Mutations in this gene have been associated with Loeys-Dietz aortic aneurysm syndrome (LDAS). Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2008] (NCBI Entrez Gene Database, 7046)
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Genes

13 genes co-occuring with the biological term tgfbr1 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol	Name
ACE	angiotensin I converting enzyme
ACTA2	actin, alpha 2, smooth muscle, aorta
AKT2	v-akt murine thymoma viral oncogene homolog 2
CCNA1	cyclin A1
CD109	CD109 molecule
FBN1	fibrillin 1
GATA3	GATA binding protein 3
MAP3K4	mitogen-activated protein kinase kinase kinase 4
MIR140	microRNA 140
PTEN	phosphatase and tensin homolog
TGFB1	transforming growth factor, beta 1
TGFBR1	transforming growth factor, beta receptor 1
TGFBR2	transforming growth factor, beta receptor II (70/80kDa)