thalidomide-1411 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the thalidomide-1411 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACACA acetyl-CoA carboxylase alpha
ACOT11 acyl-CoA thioesterase 11
ACTC1 actin, alpha, cardiac muscle 1
AEN apoptosis enhancing nuclease
AGPAT2 1-acylglycerol-3-phosphate O-acyltransferase 2
APOC1 apolipoprotein C-I
ARMC7 armadillo repeat containing 7
ASTE1 asteroid homolog 1 (Drosophila)
BAZ2A bromodomain adjacent to zinc finger domain, 2A
BICC1 BicC family RNA binding protein 1
C2ORF27A chromosome 2 open reading frame 27A
C4BPA complement component 4 binding protein, alpha
C9ORF16 chromosome 9 open reading frame 16
CAMKV CaM kinase-like vesicle-associated
CCSER2 coiled-coil serine-rich protein 2
CDC42 cell division cycle 42
CLCN6 chloride channel, voltage-sensitive 6
CLTA clathrin, light chain A
CNNM2 cyclin and CBS domain divalent metal cation transport mediator 2
COMT catechol-O-methyltransferase
CR1 complement component (3b/4b) receptor 1 (Knops blood group)
DDX11 DEAD/H (Asp-Glu-Ala-Asp/His) box helicase 11
DGCR8 DGCR8 microprocessor complex subunit
DIO2 deiodinase, iodothyronine, type II
DRP2 dystrophin related protein 2
DUS2 dihydrouridine synthase 2
DXO decapping exoribonuclease
EGR4 early growth response 4
ELMO2 engulfment and cell motility 2
EPOR erythropoietin receptor
ERAP1 endoplasmic reticulum aminopeptidase 1
ERAP2 endoplasmic reticulum aminopeptidase 2
FAM63A family with sequence similarity 63, member A
FBXO31 F-box protein 31
FBXO41 F-box protein 41
FBXO42 F-box protein 42
FCGRT Fc fragment of IgG, receptor, transporter, alpha
FN1 fibronectin 1
GOLGA8A golgin A8 family, member A
GTF3C2 general transcription factor IIIC, polypeptide 2, beta 110kDa
HIF1AN hypoxia inducible factor 1, alpha subunit inhibitor
HMOX2 heme oxygenase 2
HOOK2 hook microtubule-tethering protein 2
IDH3G isocitrate dehydrogenase 3 (NAD+) gamma
IFI35 interferon-induced protein 35
IL1RAPL2 interleukin 1 receptor accessory protein-like 2
ING4 inhibitor of growth family, member 4
IRF2BP1 interferon regulatory factor 2 binding protein 1
JRKL JRK-like
LILRA2 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 2
LRRFIP2 leucine rich repeat (in FLII) interacting protein 2
MAGOH2P mago-nashi homolog 2, pseudogene
MAN1B1 mannosidase, alpha, class 1B, member 1
MINK1 misshapen-like kinase 1
MYL10 myosin, light chain 10, regulatory
MYO1C myosin IC
NCAPH2 non-SMC condensin II complex, subunit H2
NEDD9 neural precursor cell expressed, developmentally down-regulated 9
NOL12 nucleolar protein 12
NPEPPS aminopeptidase puromycin sensitive
NUDT2 nudix (nucleoside diphosphate linked moiety X)-type motif 2
PCSK6 proprotein convertase subtilisin/kexin type 6
PLCB1 phospholipase C, beta 1 (phosphoinositide-specific)
PPP1R16B protein phosphatase 1, regulatory subunit 16B
PPP1R7 protein phosphatase 1, regulatory subunit 7
PRDM11 PR domain containing 11
PRKCA protein kinase C, alpha
PSD4 pleckstrin and Sec7 domain containing 4
RNF141 ring finger protein 141
RSL1D1 ribosomal L1 domain containing 1
RUNDC3A RUN domain containing 3A
SCML1 sex comb on midleg-like 1 (Drosophila)
SGSM2 small G protein signaling modulator 2
SGSM3 small G protein signaling modulator 3
SH3BP5 SH3-domain binding protein 5 (BTK-associated)
SIPA1 signal-induced proliferation-associated 1
SKAP1 src kinase associated phosphoprotein 1
SLC12A4 solute carrier family 12 (potassium/chloride transporter), member 4
SLC22A18AS solute carrier family 22 (organic cation transporter), member 18 antisense
SLC5A5 solute carrier family 5 (sodium/iodide cotransporter), member 5
SMARCD1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1
SPN sialophorin
SSTR4 somatostatin receptor 4
STAC SH3 and cysteine rich domain
TFE3 transcription factor binding to IGHM enhancer 3
TLN2 talin 2
TMEM161A transmembrane protein 161A
TRIM14 tripartite motif containing 14
TTC23 tetratricopeptide repeat domain 23
UBOX5 U-box domain containing 5
USF2 upstream transcription factor 2, c-fos interacting
VIPR2 vasoactive intestinal peptide receptor 2
WDR44 WD repeat domain 44
WNT10B wingless-type MMTV integration site family, member 10B
ZNF224 zinc finger protein 224
ZNF280D zinc finger protein 280D
ZNF337 zinc finger protein 337
ZNF692 zinc finger protein 692

decreased expression

Symbol Name
AAAS achalasia, adrenocortical insufficiency, alacrimia
ACTR8 ARP8 actin-related protein 8 homolog (yeast)
ACVR2B activin A receptor, type IIB
AP5S1 adaptor-related protein complex 5, sigma 1 subunit
ARGLU1 arginine and glutamate rich 1
ARMC6 armadillo repeat containing 6
AXIN1 axin 1
B3GNT2 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2
C1ORF35 chromosome 1 open reading frame 35
CAMTA2 calmodulin binding transcription activator 2
CASZ1 castor zinc finger 1
CCNT1 cyclin T1
CD151 CD151 molecule (Raph blood group)
CEND1 cell cycle exit and neuronal differentiation 1
CENPT centromere protein T
CER1 cerberus 1, DAN family BMP antagonist
CFAP74 cilia and flagella associated protein 74
CHRNB2 cholinergic receptor, nicotinic, beta 2 (neuronal)
CLN6 ceroid-lipofuscinosis, neuronal 6, late infantile, variant
COG7 component of oligomeric golgi complex 7
CRIPT cysteine-rich PDZ-binding protein
DBF4 DBF4 zinc finger
DCUN1D2 DCN1, defective in cullin neddylation 1, domain containing 2
DDX31 DEAD (Asp-Glu-Ala-Asp) box polypeptide 31
DRD5 dopamine receptor D5
DYRK4 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 4
EDAR ectodysplasin A receptor
EIF2S3 eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa
EMC6 ER membrane protein complex subunit 6
ENAH enabled homolog (Drosophila)
EVL Enah/Vasp-like
FCHO1 FCH domain only 1
GJD2 gap junction protein, delta 2, 36kDa
GRM4 glutamate receptor, metabotropic 4
GRM6 glutamate receptor, metabotropic 6
HIST1H1C histone cluster 1, H1c
IMPACT impact RWD domain protein
IMPAD1 inositol monophosphatase domain containing 1
ITPKC inositol-trisphosphate 3-kinase C
KCNMB1 potassium channel subfamily M regulatory beta subunit 1
KDELC1 KDEL (Lys-Asp-Glu-Leu) containing 1
KIF23 kinesin family member 23
KIFAP3 kinesin-associated protein 3
KRI1 KRI1 homolog (S. cerevisiae)
MANBA mannosidase, beta A, lysosomal
MAP1S microtubule-associated protein 1S
MAPK10 mitogen-activated protein kinase 10
MBTD1 mbt domain containing 1
MMS19 MMS19 nucleotide excision repair homolog (S. cerevisiae)
MRM1 mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae)
NFE2 nuclear factor, erythroid 2
NRGN neurogranin (protein kinase C substrate, RC3)
OCEL1 occludin/ELL domain containing 1
P3H1 prolyl 3-hydroxylase 1
PGLYRP4 peptidoglycan recognition protein 4
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
PKN1 protein kinase N1
POMT1 protein-O-mannosyltransferase 1
PPP1R14D protein phosphatase 1, regulatory (inhibitor) subunit 14D
PPP6R3 protein phosphatase 6, regulatory subunit 3
PRR14L proline rich 14-like
PSTPIP1 proline-serine-threonine phosphatase interacting protein 1
RFPL3 ret finger protein-like 3
SCN10A sodium channel, voltage gated, type X alpha subunit
SEC22A SEC22 vesicle trafficking protein homolog A (S. cerevisiae)
SELP selectin P (granule membrane protein 140kDa, antigen CD62)
SETD6 SET domain containing 6
SETMAR SET domain and mariner transposase fusion gene
SIRT6 sirtuin 6
SLC10A1 solute carrier family 10 (sodium/bile acid cotransporter), member 1
SLC27A5 solute carrier family 27 (fatty acid transporter), member 5
SLPI secretory leukocyte peptidase inhibitor
SNIP1 Smad nuclear interacting protein 1
SNTA1 syntrophin, alpha 1
SPIN1 spindlin 1
SSBP3 single stranded DNA binding protein 3
STARD8 StAR-related lipid transfer (START) domain containing 8
TAF12 TAF12 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 20kDa
TAF1A TATA box binding protein (TBP)-associated factor, RNA polymerase I, A, 48kDa
TBL3 transducin (beta)-like 3
TEFM transcription elongation factor, mitochondrial
TET3 tet methylcytosine dioxygenase 3
TGFBRAP1 transforming growth factor, beta receptor associated protein 1
TGIF1 TGFB-induced factor homeobox 1
TIAM2 T-cell lymphoma invasion and metastasis 2
TLN1 talin 1
TMEM184C transmembrane protein 184C
TMEM38B transmembrane protein 38B
TMEM62 transmembrane protein 62
TOPORS topoisomerase I binding, arginine/serine-rich, E3 ubiquitin protein ligase
TTPAL tocopherol (alpha) transfer protein-like
UBE2NL ubiquitin-conjugating enzyme E2N-like (gene/pseudogene)
UGGT1 UDP-glucose glycoprotein glucosyltransferase 1
XPO4 exportin 4
YARS2 tyrosyl-tRNA synthetase 2, mitochondrial
ZDHHC13 zinc finger, DHHC-type containing 13
ZNF273 zinc finger protein 273
ZNF408 zinc finger protein 408
ZNF839 zinc finger protein 839
ZNHIT2 zinc finger, HIT-type containing 2