| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
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197 genes differentially expressed following the thalidomide-2095 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| AAGAB | alpha- and gamma-adaptin binding protein |
| ADTRP | androgen-dependent TFPI-regulating protein |
| ALAD | aminolevulinate dehydratase |
| ANKMY1 | ankyrin repeat and MYND domain containing 1 |
| APOBEC3G | apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3G |
| ARHGAP35 | Rho GTPase activating protein 35 |
| ATG10 | autophagy related 10 |
| ATP11A | ATPase, class VI, type 11A |
| AURKA | aurora kinase A |
| BAIAP3 | BAI1-associated protein 3 |
| C10ORF10 | chromosome 10 open reading frame 10 |
| C16ORF59 | chromosome 16 open reading frame 59 |
| C8A | complement component 8, alpha polypeptide |
| CALD1 | caldesmon 1 |
| CASP1 | caspase 1, apoptosis-related cysteine peptidase |
| CCDC71 | coiled-coil domain containing 71 |
| CCKAR | cholecystokinin A receptor |
| CHST8 | carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 8 |
| COLGALT2 | collagen beta(1-O)galactosyltransferase 2 |
| CSN2 | casein beta |
| CTIF | CBP80/20-dependent translation initiation factor |
| DCAF15 | DDB1 and CUL4 associated factor 15 |
| DCN | decorin |
| DDX6 | DEAD (Asp-Glu-Ala-Asp) box helicase 6 |
| DHRS9 | dehydrogenase/reductase (SDR family) member 9 |
| DNAJC28 | DnaJ (Hsp40) homolog, subfamily C, member 28 |
| DPF3 | D4, zinc and double PHD fingers, family 3 |
| EFNB1 | ephrin-B1 |
| EMP1 | epithelial membrane protein 1 |
| EVI5 | ecotropic viral integration site 5 |
| EWSR1 | EWS RNA-binding protein 1 |
| EXOSC1 | exosome component 1 |
| FKBP8 | FK506 binding protein 8, 38kDa |
| FLJ21369 | uncharacterized protein FLJ21369 |
| FN1 | fibronectin 1 |
| FZR1 | fizzy/cell division cycle 20 related 1 (Drosophila) |
| GLI2 | GLI family zinc finger 2 |
| GSK3A | glycogen synthase kinase 3 alpha |
| GSTA3 | glutathione S-transferase alpha 3 |
| HLA-DPA1 | major histocompatibility complex, class II, DP alpha 1 |
| IGHG1 | immunoglobulin heavy constant gamma 1 (G1m marker) |
| IL36RN | interleukin 36 receptor antagonist |
| IL6ST | interleukin 6 signal transducer |
| IRF2BP1 | interferon regulatory factor 2 binding protein 1 |
| KIR2DL3 | killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 3 |
| KLK10 | kallikrein-related peptidase 10 |
| LINC00260 | long intergenic non-protein coding RNA 260 |
| LMF1 | lipase maturation factor 1 |
| LPAR4 | lysophosphatidic acid receptor 4 |
| MAPK8IP1 | mitogen-activated protein kinase 8 interacting protein 1 |
| MATN1 | matrilin 1, cartilage matrix protein |
| MIIP | migration and invasion inhibitory protein |
| MNMIP1 | manchette microtubule inner protein 1 |
| MST1 | macrophage stimulating 1 |
| MTUS1 | microtubule associated tumor suppressor 1 |
| MUC3B | mucin 3B, cell surface associated |
| MYL4 | myosin, light chain 4, alkali; atrial, embryonic |
| NOL4 | nucleolar protein 4 |
| NUMA1 | nuclear mitotic apparatus protein 1 |
| OAZ3 | ornithine decarboxylase antizyme 3 |
| OPCML | opioid binding protein/cell adhesion molecule-like |
| PAX8 | paired box 8 |
| PDE4DIP | phosphodiesterase 4D interacting protein |
| PDGFA | platelet-derived growth factor alpha polypeptide |
| PGLYRP1 | peptidoglycan recognition protein 1 |
| PKP3 | plakophilin 3 |
| PRR14L | proline rich 14-like |
| PRR5 | proline rich 5 (renal) |
| PTCRA | pre T-cell antigen receptor alpha |
| RAB28 | RAB28, member RAS oncogene family |
| REST | RE1-silencing transcription factor |
| RETN | resistin |
| RGS10 | regulator of G-protein signaling 10 |
| RGS12 | regulator of G-protein signaling 12 |
| RNF122 | ring finger protein 122 |
| RSPH14 | radial spoke head 14 homolog (Chlamydomonas) |
| S100A5 | S100 calcium binding protein A5 |
| SERPINB3 | serpin peptidase inhibitor, clade B (ovalbumin), member 3 |
| SLC13A1 | solute carrier family 13 (sodium/sulfate symporter), member 1 |
| SLC39A2 | solute carrier family 39 (zinc transporter), member 2 |
| SLC48A1 | solute carrier family 48 (heme transporter), member 1 |
| SLITRK5 | SLIT and NTRK-like family, member 5 |
| SMR3A | submaxillary gland androgen regulated protein 3A |
| SOGA1 | suppressor of glucose, autophagy associated 1 |
| STX2 | syntaxin 2 |
| SYT2 | synaptotagmin II |
| TBC1D1 | TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member 1 |
| TBC1D30 | TBC1 domain family, member 30 |
| TELO2 | telomere maintenance 2 |
| TK2 | thymidine kinase 2, mitochondrial |
| TNFSF15 | tumor necrosis factor (ligand) superfamily, member 15 |
| TPM1 | tropomyosin 1 (alpha) |
| TRIM29 | tripartite motif containing 29 |
| UCHL1 | ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) |
| USP48 | ubiquitin specific peptidase 48 |
| VAV3 | vav 3 guanine nucleotide exchange factor |
| ZNF385D | zinc finger protein 385D |
| ZNHIT2 | zinc finger, HIT-type containing 2 |
| Symbol | Name |
|---|---|
| ACTR8 | ARP8 actin-related protein 8 homolog (yeast) |
| ADAM15 | ADAM metallopeptidase domain 15 |
| ADCY6 | adenylate cyclase 6 |
| ADPRM | ADP-ribose/CDP-alcohol diphosphatase, manganese-dependent |
| ANKEF1 | ankyrin repeat and EF-hand domain containing 1 |
| ANOS1 | anosmin 1 |
| ANXA2P3 | annexin A2 pseudogene 3 |
| AP1AR | adaptor-related protein complex 1 associated regulatory protein |
| ARL14 | ADP-ribosylation factor-like 14 |
| ARRB2 | arrestin, beta 2 |
| ASB8 | ankyrin repeat and SOCS box containing 8 |
| ATP11B | ATPase, class VI, type 11B |
| AXIN1 | axin 1 |
| BDNF | brain-derived neurotrophic factor |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 |
| C1ORF112 | chromosome 1 open reading frame 112 |
| C7ORF43 | chromosome 7 open reading frame 43 |
| CARD8 | caspase recruitment domain family, member 8 |
| CASD1 | CAS1 domain containing 1 |
| CBX7 | chromobox homolog 7 |
| CCDC6 | coiled-coil domain containing 6 |
| CCNT1 | cyclin T1 |
| CDKN2D | cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4) |
| CHST11 | carbohydrate (chondroitin 4) sulfotransferase 11 |
| CNNM3 | cyclin and CBS domain divalent metal cation transport mediator 3 |
| COL4A3BP | collagen, type IV, alpha 3 (Goodpasture antigen) binding protein |
| CXORF56 | chromosome X open reading frame 56 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 |
| DIXDC1 | DIX domain containing 1 |
| DMTF1 | cyclin D binding myb-like transcription factor 1 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 |
| EDC3 | enhancer of mRNA decapping 3 |
| EEF2KMT | eukaryotic elongation factor 2 lysine methyltransferase |
| EIF2S3 | eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa |
| FAM102A | family with sequence similarity 102, member A |
| FIP1L1 | factor interacting with PAPOLA and CPSF1 |
| GDAP2 | ganglioside induced differentiation associated protein 2 |
| GID4 | GID complex subunit 4 |
| GLT8D2 | glycosyltransferase 8 domain containing 2 |
| GNA13 | guanine nucleotide binding protein (G protein), alpha 13 |
| GPR176 | G protein-coupled receptor 176 |
| GUSBP3 | glucuronidase, beta pseudogene 3 |
| HAUS6 | HAUS augmin-like complex, subunit 6 |
| HIRA | histone cell cycle regulator |
| HIST1H2AG | histone cluster 1, H2ag |
| HMGB3P1 | high mobility group box 3 pseudogene 1 |
| HMOX1 | heme oxygenase 1 |
| HS1BP3 | HCLS1 binding protein 3 |
| KCNMB3 | potassium channel subfamily M regulatory beta subunit 3 |
| KIAA0556 | KIAA0556 |
| KIFAP3 | kinesin-associated protein 3 |
| KPTN | kaptin (actin binding protein) |
| LMAN1 | lectin, mannose-binding, 1 |
| LMNB1 | lamin B1 |
| LONRF3 | LON peptidase N-terminal domain and ring finger 3 |
| LRP5 | low density lipoprotein receptor-related protein 5 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 |
| MBTPS2 | membrane-bound transcription factor peptidase, site 2 |
| NBEAL2 | neurobeachin-like 2 |
| NID2 | nidogen 2 (osteonidogen) |
| NINL | ninein-like |
| NPR3 | natriuretic peptide receptor 3 |
| P2RX4 | purinergic receptor P2X, ligand gated ion channel, 4 |
| PDSS2 | prenyl (decaprenyl) diphosphate synthase, subunit 2 |
| PLA2G4A | phospholipase A2, group IVA (cytosolic, calcium-dependent) |
| PLCB3 | phospholipase C, beta 3 (phosphatidylinositol-specific) |
| PLSCR4 | phospholipid scramblase 4 |
| PMPCA | peptidase (mitochondrial processing) alpha |
| PPBP | pro-platelet basic protein (chemokine (C-X-C motif) ligand 7) |
| PPIP5K1 | diphosphoinositol pentakisphosphate kinase 1 |
| PPP2R2D | protein phosphatase 2, regulatory subunit B, delta |
| PUS7L | pseudouridylate synthase 7 homolog (S. cerevisiae)-like |
| RAD54L2 | RAD54-like 2 (S. cerevisiae) |
| RIC8B | RIC8 guanine nucleotide exchange factor B |
| SAMD9 | sterile alpha motif domain containing 9 |
| SCYL2 | SCY1-like 2 (S. cerevisiae) |
| SHROOM2 | shroom family member 2 |
| SLC20A2 | solute carrier family 20 (phosphate transporter), member 2 |
| SLC25A23 | solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23 |
| SLC26A6 | solute carrier family 26 (anion exchanger), member 6 |
| SLC41A3 | solute carrier family 41, member 3 |
| SPRY1 | sprouty homolog 1, antagonist of FGF signaling (Drosophila) |
| TCTN1 | tectonic family member 1 |
| TESK2 | testis-specific kinase 2 |
| TIMM10B | translocase of inner mitochondrial membrane 10 homolog B (yeast) |
| TMEM183A | transmembrane protein 183A |
| TMEM242 | transmembrane protein 242 |
| TMSB15A | thymosin beta 15a |
| TNKS2 | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2 |
| TUBGCP5 | tubulin, gamma complex associated protein 5 |
| UGGT2 | UDP-glucose glycoprotein glucosyltransferase 2 |
| USP5 | ubiquitin specific peptidase 5 (isopeptidase T) |
| VWA1 | von Willebrand factor A domain containing 1 |
| ZC3H3 | zinc finger CCCH-type containing 3 |
| ZMAT5 | zinc finger, matrin-type 5 |
| ZNF195 | zinc finger protein 195 |
| ZNF215 | zinc finger protein 215 |
| ZNF273 | zinc finger protein 273 |
| ZNF665 | zinc finger protein 665 |