thalidomide-2095 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the thalidomide-2095 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AAGAB alpha- and gamma-adaptin binding protein
ADTRP androgen-dependent TFPI-regulating protein
ALAD aminolevulinate dehydratase
ANKMY1 ankyrin repeat and MYND domain containing 1
APOBEC3G apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3G
ARHGAP35 Rho GTPase activating protein 35
ATG10 autophagy related 10
ATP11A ATPase, class VI, type 11A
AURKA aurora kinase A
BAIAP3 BAI1-associated protein 3
C10ORF10 chromosome 10 open reading frame 10
C16ORF59 chromosome 16 open reading frame 59
C8A complement component 8, alpha polypeptide
CALD1 caldesmon 1
CASP1 caspase 1, apoptosis-related cysteine peptidase
CCDC71 coiled-coil domain containing 71
CCKAR cholecystokinin A receptor
CHST8 carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 8
COLGALT2 collagen beta(1-O)galactosyltransferase 2
CSN2 casein beta
CTIF CBP80/20-dependent translation initiation factor
DCAF15 DDB1 and CUL4 associated factor 15
DCN decorin
DDX6 DEAD (Asp-Glu-Ala-Asp) box helicase 6
DHRS9 dehydrogenase/reductase (SDR family) member 9
DNAJC28 DnaJ (Hsp40) homolog, subfamily C, member 28
DPF3 D4, zinc and double PHD fingers, family 3
EFNB1 ephrin-B1
EMP1 epithelial membrane protein 1
EVI5 ecotropic viral integration site 5
EWSR1 EWS RNA-binding protein 1
EXOSC1 exosome component 1
FKBP8 FK506 binding protein 8, 38kDa
FLJ21369 uncharacterized protein FLJ21369
FN1 fibronectin 1
FZR1 fizzy/cell division cycle 20 related 1 (Drosophila)
GLI2 GLI family zinc finger 2
GSK3A glycogen synthase kinase 3 alpha
GSTA3 glutathione S-transferase alpha 3
HLA-DPA1 major histocompatibility complex, class II, DP alpha 1
IGHG1 immunoglobulin heavy constant gamma 1 (G1m marker)
IL36RN interleukin 36 receptor antagonist
IL6ST interleukin 6 signal transducer
IRF2BP1 interferon regulatory factor 2 binding protein 1
KIR2DL3 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 3
KLK10 kallikrein-related peptidase 10
LINC00260 long intergenic non-protein coding RNA 260
LMF1 lipase maturation factor 1
LPAR4 lysophosphatidic acid receptor 4
MAPK8IP1 mitogen-activated protein kinase 8 interacting protein 1
MATN1 matrilin 1, cartilage matrix protein
MIIP migration and invasion inhibitory protein
MNMIP1 manchette microtubule inner protein 1
MST1 macrophage stimulating 1
MTUS1 microtubule associated tumor suppressor 1
MUC3B mucin 3B, cell surface associated
MYL4 myosin, light chain 4, alkali; atrial, embryonic
NOL4 nucleolar protein 4
NUMA1 nuclear mitotic apparatus protein 1
OAZ3 ornithine decarboxylase antizyme 3
OPCML opioid binding protein/cell adhesion molecule-like
PAX8 paired box 8
PDE4DIP phosphodiesterase 4D interacting protein
PDGFA platelet-derived growth factor alpha polypeptide
PGLYRP1 peptidoglycan recognition protein 1
PKP3 plakophilin 3
PRR14L proline rich 14-like
PRR5 proline rich 5 (renal)
PTCRA pre T-cell antigen receptor alpha
RAB28 RAB28, member RAS oncogene family
REST RE1-silencing transcription factor
RETN resistin
RGS10 regulator of G-protein signaling 10
RGS12 regulator of G-protein signaling 12
RNF122 ring finger protein 122
RSPH14 radial spoke head 14 homolog (Chlamydomonas)
S100A5 S100 calcium binding protein A5
SERPINB3 serpin peptidase inhibitor, clade B (ovalbumin), member 3
SLC13A1 solute carrier family 13 (sodium/sulfate symporter), member 1
SLC39A2 solute carrier family 39 (zinc transporter), member 2
SLC48A1 solute carrier family 48 (heme transporter), member 1
SLITRK5 SLIT and NTRK-like family, member 5
SMR3A submaxillary gland androgen regulated protein 3A
SOGA1 suppressor of glucose, autophagy associated 1
STX2 syntaxin 2
SYT2 synaptotagmin II
TBC1D1 TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member 1
TBC1D30 TBC1 domain family, member 30
TELO2 telomere maintenance 2
TK2 thymidine kinase 2, mitochondrial
TNFSF15 tumor necrosis factor (ligand) superfamily, member 15
TPM1 tropomyosin 1 (alpha)
TRIM29 tripartite motif containing 29
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
USP48 ubiquitin specific peptidase 48
VAV3 vav 3 guanine nucleotide exchange factor
ZNF385D zinc finger protein 385D
ZNHIT2 zinc finger, HIT-type containing 2

decreased expression

Symbol Name
ACTR8 ARP8 actin-related protein 8 homolog (yeast)
ADAM15 ADAM metallopeptidase domain 15
ADCY6 adenylate cyclase 6
ADPRM ADP-ribose/CDP-alcohol diphosphatase, manganese-dependent
ANKEF1 ankyrin repeat and EF-hand domain containing 1
ANOS1 anosmin 1
ANXA2P3 annexin A2 pseudogene 3
AP1AR adaptor-related protein complex 1 associated regulatory protein
ARL14 ADP-ribosylation factor-like 14
ARRB2 arrestin, beta 2
ASB8 ankyrin repeat and SOCS box containing 8
ATP11B ATPase, class VI, type 11B
AXIN1 axin 1
BDNF brain-derived neurotrophic factor
BRIP1 BRCA1 interacting protein C-terminal helicase 1
C1ORF112 chromosome 1 open reading frame 112
C7ORF43 chromosome 7 open reading frame 43
CARD8 caspase recruitment domain family, member 8
CASD1 CAS1 domain containing 1
CBX7 chromobox homolog 7
CCDC6 coiled-coil domain containing 6
CCNT1 cyclin T1
CDKN2D cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)
CHST11 carbohydrate (chondroitin 4) sulfotransferase 11
CNNM3 cyclin and CBS domain divalent metal cation transport mediator 3
COL4A3BP collagen, type IV, alpha 3 (Goodpasture antigen) binding protein
CXORF56 chromosome X open reading frame 56
DCBLD2 discoidin, CUB and LCCL domain containing 2
DIXDC1 DIX domain containing 1
DMTF1 cyclin D binding myb-like transcription factor 1
DNAJC3 DnaJ (Hsp40) homolog, subfamily C, member 3
EDC3 enhancer of mRNA decapping 3
EEF2KMT eukaryotic elongation factor 2 lysine methyltransferase
EIF2S3 eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa
FAM102A family with sequence similarity 102, member A
FIP1L1 factor interacting with PAPOLA and CPSF1
GDAP2 ganglioside induced differentiation associated protein 2
GID4 GID complex subunit 4
GLT8D2 glycosyltransferase 8 domain containing 2
GNA13 guanine nucleotide binding protein (G protein), alpha 13
GPR176 G protein-coupled receptor 176
GUSBP3 glucuronidase, beta pseudogene 3
HAUS6 HAUS augmin-like complex, subunit 6
HIRA histone cell cycle regulator
HIST1H2AG histone cluster 1, H2ag
HMGB3P1 high mobility group box 3 pseudogene 1
HMOX1 heme oxygenase 1
HS1BP3 HCLS1 binding protein 3
KCNMB3 potassium channel subfamily M regulatory beta subunit 3
KIAA0556 KIAA0556
KIFAP3 kinesin-associated protein 3
KPTN kaptin (actin binding protein)
LMAN1 lectin, mannose-binding, 1
LMNB1 lamin B1
LONRF3 LON peptidase N-terminal domain and ring finger 3
LRP5 low density lipoprotein receptor-related protein 5
MAP3K2 mitogen-activated protein kinase kinase kinase 2
MBTPS2 membrane-bound transcription factor peptidase, site 2
NBEAL2 neurobeachin-like 2
NID2 nidogen 2 (osteonidogen)
NINL ninein-like
NPR3 natriuretic peptide receptor 3
P2RX4 purinergic receptor P2X, ligand gated ion channel, 4
PDSS2 prenyl (decaprenyl) diphosphate synthase, subunit 2
PLA2G4A phospholipase A2, group IVA (cytosolic, calcium-dependent)
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific)
PLSCR4 phospholipid scramblase 4
PMPCA peptidase (mitochondrial processing) alpha
PPBP pro-platelet basic protein (chemokine (C-X-C motif) ligand 7)
PPIP5K1 diphosphoinositol pentakisphosphate kinase 1
PPP2R2D protein phosphatase 2, regulatory subunit B, delta
PUS7L pseudouridylate synthase 7 homolog (S. cerevisiae)-like
RAD54L2 RAD54-like 2 (S. cerevisiae)
RIC8B RIC8 guanine nucleotide exchange factor B
SAMD9 sterile alpha motif domain containing 9
SCYL2 SCY1-like 2 (S. cerevisiae)
SHROOM2 shroom family member 2
SLC20A2 solute carrier family 20 (phosphate transporter), member 2
SLC25A23 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23
SLC26A6 solute carrier family 26 (anion exchanger), member 6
SLC41A3 solute carrier family 41, member 3
SPRY1 sprouty homolog 1, antagonist of FGF signaling (Drosophila)
TCTN1 tectonic family member 1
TESK2 testis-specific kinase 2
TIMM10B translocase of inner mitochondrial membrane 10 homolog B (yeast)
TMEM183A transmembrane protein 183A
TMEM242 transmembrane protein 242
TMSB15A thymosin beta 15a
TNKS2 tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2
TUBGCP5 tubulin, gamma complex associated protein 5
UGGT2 UDP-glucose glycoprotein glucosyltransferase 2
USP5 ubiquitin specific peptidase 5 (isopeptidase T)
VWA1 von Willebrand factor A domain containing 1
ZC3H3 zinc finger CCCH-type containing 3
ZMAT5 zinc finger, matrin-type 5
ZNF195 zinc finger protein 195
ZNF215 zinc finger protein 215
ZNF273 zinc finger protein 273
ZNF665 zinc finger protein 665