thapsigargin-7053 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

196 genes differentially expressed following the thapsigargin-7053 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AMOTL2 angiomotin like 2
ANG angiogenin, ribonuclease, RNase A family, 5
AREG amphiregulin
ARFGAP3 ADP-ribosylation factor GTPase activating protein 3
ARHGEF2 Rho/Rac guanine nucleotide exchange factor (GEF) 2
ARTN artemin
ATF3 activating transcription factor 3
BET1 Bet1 golgi vesicular membrane trafficking protein
BHLHE40 basic helix-loop-helix family, member e40
C17ORF59 chromosome 17 open reading frame 59
CAMTA2 calmodulin binding transcription activator 2
CBX4 chromobox homolog 4
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group)
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CLGN calmegin
CRELD1 cysteine-rich with EGF-like domains 1
DDIT3 DNA-damage-inducible transcript 3
DDIT4 DNA-damage-inducible transcript 4
DNAJB9 DnaJ (Hsp40) homolog, subfamily B, member 9
DNAJC12 DnaJ (Hsp40) homolog, subfamily C, member 12
EAF2 ELL associated factor 2
EDEM1 ER degradation enhancer, mannosidase alpha-like 1
EPOR erythropoietin receptor
ERO1LB ERO1-like beta (S. cerevisiae)
ERP44 endoplasmic reticulum protein 44
ETV5 ets variant 5
FAM129A family with sequence similarity 129, member A
FICD FIC domain containing
FKBP14 FK506 binding protein 14, 22 kDa
FLJ42627 uncharacterized LOC645644
FUT1 fucosyltransferase 1 (galactoside 2-alpha-L-fucosyltransferase, H blood group)
FUT3 fucosyltransferase 3 (galactoside 3(4)-L-fucosyltransferase, Lewis blood group)
FYN FYN proto-oncogene, Src family tyrosine kinase
GADD45A growth arrest and DNA-damage-inducible, alpha
GLRX glutaredoxin (thioltransferase)
GTPBP2 GTP binding protein 2
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
HIST1H2BO histone cluster 1, H2bo
HSPA13 heat shock protein 70kDa family, member 13
HYOU1 hypoxia up-regulated 1
INHBE inhibin, beta E
ISG20 interferon stimulated exonuclease gene 20kDa
KIAA0513 KIAA0513
KIZ kizuna centrosomal protein
LAMP3 lysosomal-associated membrane protein 3
LARP6 La ribonucleoprotein domain family, member 6
LPIN1 lipin 1
LZTFL1 leucine zipper transcription factor-like 1
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MANF mesencephalic astrocyte-derived neurotrophic factor
MAP1B microtubule-associated protein 1B
MAP1LC3B microtubule-associated protein 1 light chain 3 beta
MBNL2 muscleblind-like splicing regulator 2
MGAT2 mannosyl (alpha-1,6-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase
MIR22HG MIR22 host gene
MT1HL1 metallothionein 1H-like 1
MTUS2 microtubule associated tumor suppressor candidate 2
N4BP2L2 NEDD4 binding protein 2-like 2
NFIL3 nuclear factor, interleukin 3 regulated
NUPR1 nuclear protein, transcriptional regulator, 1
PCK2 phosphoenolpyruvate carboxykinase 2 (mitochondrial)
PDIA4 protein disulfide isomerase family A, member 4
PLA2G3 phospholipase A2, group III
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1
POPDC3 popeye domain containing 3
PPP1R15A protein phosphatase 1, regulatory subunit 15A
RCAN1 regulator of calcineurin 1
RHOQ ras homolog family member Q
RNASE4 ribonuclease, RNase A family, 4
RPGR retinitis pigmentosa GTPase regulator
RRBP1 ribosome binding protein 1
SDF2L1 stromal cell-derived factor 2-like 1
SEC23B Sec23 homolog B (S. cerevisiae)
SEC24D SEC24 family member D
SEL1L sel-1 suppressor of lin-12-like (C. elegans)
SH3BGR SH3 domain binding glutamate-rich protein
SH3TC1 SH3 domain and tetratricopeptide repeats 1
SLC1A4 solute carrier family 1 (glutamate/neutral amino acid transporter), member 4
SLC2A10 solute carrier family 2 (facilitated glucose transporter), member 10
SLC31A1 solute carrier family 31 (copper transporter), member 1
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SOX9 SRY (sex determining region Y)-box 9
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5
TES testin LIM domain protein
THBD thrombomodulin
TMEM39A transmembrane protein 39A
TRIB1 tribbles pseudokinase 1
TRIM2 tripartite motif containing 2
TSPYL2 TSPY-like 2
TULP3 tubby like protein 3
TXNIP thioredoxin interacting protein
ULBP2 UL16 binding protein 2
VAMP2 vesicle-associated membrane protein 2 (synaptobrevin 2)
VEGFA vascular endothelial growth factor A
VLDLR very low density lipoprotein receptor
WARS tryptophanyl-tRNA synthetase
WIPI1 WD repeat domain, phosphoinositide interacting 1
ZNF165 zinc finger protein 165

decreased expression

Symbol Name
ACKR3 atypical chemokine receptor 3
ACYP1 acylphosphatase 1, erythrocyte (common) type
ADAM15 ADAM metallopeptidase domain 15
ADCY6 adenylate cyclase 6
ADGRA3 adhesion G protein-coupled receptor A3
ADGRE5 adhesion G protein-coupled receptor E5
AKR1C3 aldo-keto reductase family 1, member C3
ARHGEF3 Rho guanine nucleotide exchange factor (GEF) 3
B3GNT1
B3GNT2 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2
BDH2 3-hydroxybutyrate dehydrogenase, type 2
BMP4 bone morphogenetic protein 4
BRINP3 bone morphogenetic protein/retinoic acid inducible neural-specific 3
C1ORF115 chromosome 1 open reading frame 115
C1ORF159 chromosome 1 open reading frame 159
C9ORF114 chromosome 9 open reading frame 114
CA2 carbonic anhydrase II
CCNE2 cyclin E2
CGA glycoprotein hormones, alpha polypeptide
CHST10 carbohydrate sulfotransferase 10
CLDN11 claudin 11
DAPP1 dual adaptor of phosphotyrosine and 3-phosphoinositides
DNAJA1 DnaJ (Hsp40) homolog, subfamily A, member 1
DNMT3B DNA (cytosine-5-)-methyltransferase 3 beta
DUSP2 dual specificity phosphatase 2
E2F8 E2F transcription factor 8
EIF5A2 eukaryotic translation initiation factor 5A2
EPPK1 epiplakin 1
ERCC6L excision repair cross-complementation group 6-like
FAM111A family with sequence similarity 111, member A
FASTKD1 FAST kinase domains 1
FASTKD5 FAST kinase domains 5
FHOD1 formin homology 2 domain containing 1
FKBP5 FK506 binding protein 5
FLT4 fms-related tyrosine kinase 4
FMO4 flavin containing monooxygenase 4
FRS2 fibroblast growth factor receptor substrate 2
GATA4 GATA binding protein 4
GATA6 GATA binding protein 6
GDAP1 ganglioside induced differentiation associated protein 1
GPR19 G protein-coupled receptor 19
GRB7 growth factor receptor-bound protein 7
GTF2I general transcription factor IIi
HMGB3P1 high mobility group box 3 pseudogene 1
HSPA1A heat shock 70kDa protein 1A
HSPA2 heat shock 70kDa protein 2
HTRA1 HtrA serine peptidase 1
IGSF3 immunoglobulin superfamily, member 3
IL17RA interleukin 17 receptor A
IPO8 importin 8
IRX5 iroquois homeobox 5
KCNS1 potassium voltage-gated channel, modifier subfamily S, member 1
KCNS3 potassium voltage-gated channel, modifier subfamily S, member 3
LOC730101 uncharacterized LOC730101
LOXL1 lysyl oxidase-like 1
MANEA mannosidase, endo-alpha
MAPKAP1 mitogen-activated protein kinase associated protein 1
MAST3 microtubule associated serine/threonine kinase 3
MEGF9 multiple EGF-like-domains 9
MUM1 melanoma associated antigen (mutated) 1
NPY1R neuropeptide Y receptor Y1
OPN3 opsin 3
OSGEPL1 O-sialoglycoprotein endopeptidase-like 1
OSMR oncostatin M receptor
PCDHB13 protocadherin beta 13
PCNA proliferating cell nuclear antigen
PCYOX1 prenylcysteine oxidase 1
PLA2G15 phospholipase A2, group XV
PLCXD1 phosphatidylinositol-specific phospholipase C, X domain containing 1
PLEC plectin
POLE2 polymerase (DNA directed), epsilon 2, accessory subunit
PPP1R3C protein phosphatase 1, regulatory subunit 3C
PRKCD protein kinase C, delta
PRRG4 proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane)
PTPN3 protein tyrosine phosphatase, non-receptor type 3
RAB29 RAB29, member RAS oncogene family
RAB30 RAB30, member RAS oncogene family
RGS19 regulator of G-protein signaling 19
RHOB ras homolog family member B
RHPN1-AS1 RHPN1 antisense RNA 1 (head to head)
RIC8B RIC8 guanine nucleotide exchange factor B
RLN2 relaxin 2
RNF126P1 ring finger protein 126 pseudogene 1
RNF38 ring finger protein 38
SALL2 spalt-like transcription factor 2
SEC14L2 SEC14-like 2 (S. cerevisiae)
SLC36A1 solute carrier family 36 (proton/amino acid symporter), member 1
SLC6A14 solute carrier family 6 (amino acid transporter), member 14
SPATA2L spermatogenesis associated 2-like
SPRYD7 SPRY domain containing 7
SUV39H2 suppressor of variegation 3-9 homolog 2 (Drosophila)
TCP10 t-complex 10
TK1 thymidine kinase 1, soluble
TMEM164 transmembrane protein 164
VWA1 von Willebrand factor A domain containing 1
ZBED1 zinc finger, BED-type containing 1
ZFP30 ZFP30 zinc finger protein
ZNF813 zinc finger protein 813