| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
| Downloads & Tools |
196 genes differentially expressed following the theobromine-2995 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ACTG2 | actin, gamma 2, smooth muscle, enteric |
| ANG | angiogenin, ribonuclease, RNase A family, 5 |
| AP4S1 | adaptor-related protein complex 4, sigma 1 subunit |
| APLP2 | amyloid beta (A4) precursor-like protein 2 |
| ARHGAP35 | Rho GTPase activating protein 35 |
| ARL2BP | ADP-ribosylation factor-like 2 binding protein |
| ATP2B3 | ATPase, Ca++ transporting, plasma membrane 3 |
| ATXN2L | ataxin 2-like |
| BAGE | B melanoma antigen |
| BCAS1 | breast carcinoma amplified sequence 1 |
| BCAS3 | breast carcinoma amplified sequence 3 |
| C21ORF2 | chromosome 21 open reading frame 2 |
| C9ORF9 | chromosome 9 open reading frame 9 |
| CALD1 | caldesmon 1 |
| CCSER2 | coiled-coil serine-rich protein 2 |
| CD1E | CD1e molecule |
| CD300C | CD300c molecule |
| CDC42EP4 | CDC42 effector protein (Rho GTPase binding) 4 |
| CEMP1 | cementum protein 1 |
| CHMP6 | charged multivesicular body protein 6 |
| COX6A2 | cytochrome c oxidase subunit VIa polypeptide 2 |
| DCN | decorin |
| DLC1 | DLC1 Rho GTPase activating protein |
| DSTYK | dual serine/threonine and tyrosine protein kinase |
| DTX2P1-UPK3BP1-PMS2P11 | DTX2P1-UPK3BP1-PMS2P11 readthrough transcribed pseudogene |
| DZIP3 | DAZ interacting zinc finger protein 3 |
| EFNB3 | ephrin-B3 |
| EHMT1 | euchromatic histone-lysine N-methyltransferase 1 |
| EIF1 | eukaryotic translation initiation factor 1 |
| EMILIN2 | elastin microfibril interfacer 2 |
| ESR2 | estrogen receptor 2 (ER beta) |
| F7 | coagulation factor VII (serum prothrombin conversion accelerator) |
| FDPS | farnesyl diphosphate synthase |
| GABARAPL1 | GABA(A) receptor-associated protein like 1 |
| GLYR1 | glyoxylate reductase 1 homolog (Arabidopsis) |
| GP5 | glycoprotein V (platelet) |
| GPRASP1 | G protein-coupled receptor associated sorting protein 1 |
| GSG1 | germ cell associated 1 |
| GSPT1 | G1 to S phase transition 1 |
| HAPLN1 | hyaluronan and proteoglycan link protein 1 |
| HDAC6 | histone deacetylase 6 |
| HIST1H2BC | histone cluster 1, H2bc |
| HTR6 | 5-hydroxytryptamine (serotonin) receptor 6, G protein-coupled |
| IGHG1 | immunoglobulin heavy constant gamma 1 (G1m marker) |
| IL1R2 | interleukin 1 receptor, type II |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 |
| JAM2 | junctional adhesion molecule 2 |
| KDSR | 3-ketodihydrosphingosine reductase |
| KHK | ketohexokinase (fructokinase) |
| KLC2 | kinesin light chain 2 |
| KMO | kynurenine 3-monooxygenase (kynurenine 3-hydroxylase) |
| KRTAP2-4 | keratin associated protein 2-4 |
| LAMA2 | laminin, alpha 2 |
| LEF1 | lymphoid enhancer-binding factor 1 |
| LEP | leptin |
| LIMS2 | LIM and senescent cell antigen-like domains 2 |
| LLPH | LLP homolog, long-term synaptic facilitation (Aplysia) |
| MAP2K7 | mitogen-activated protein kinase kinase 7 |
| MED14 | mediator complex subunit 14 |
| MMP3 | matrix metallopeptidase 3 |
| MRPS12 | mitochondrial ribosomal protein S12 |
| MTHFR | methylenetetrahydrofolate reductase (NAD(P)H) |
| MYH8 | myosin, heavy chain 8, skeletal muscle, perinatal |
| MYOZ3 | myozenin 3 |
| NFKBIL1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1 |
| NMT2 | N-myristoyltransferase 2 |
| NRG2 | neuregulin 2 |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 |
| PBX2 | pre-B-cell leukemia homeobox 2 |
| PIGR | polymeric immunoglobulin receptor |
| PKP1 | plakophilin 1 |
| PLCL2 | phospholipase C-like 2 |
| PNPLA4 | patatin-like phospholipase domain containing 4 |
| PPIL2 | peptidylprolyl isomerase (cyclophilin)-like 2 |
| PTPN13 | protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase) |
| PVR | poliovirus receptor |
| PXDC1 | PX domain containing 1 |
| RASAL2 | RAS protein activator like 2 |
| RBPMS | RNA binding protein with multiple splicing |
| RPL3L | ribosomal protein L3-like |
| SHMT1 | serine hydroxymethyltransferase 1 (soluble) |
| SLC23A2 | solute carrier family 23 (ascorbic acid transporter), member 2 |
| SMAD5 | SMAD family member 5 |
| SOCS2 | suppressor of cytokine signaling 2 |
| SPHK2 | sphingosine kinase 2 |
| SSBP2 | single-stranded DNA binding protein 2 |
| ST3GAL4 | ST3 beta-galactoside alpha-2,3-sialyltransferase 4 |
| STK3 | serine/threonine kinase 3 |
| TBX5 | T-box 5 |
| TMEM242 | transmembrane protein 242 |
| TRPS1 | trichorhinophalangeal syndrome I |
| TSPAN2 | tetraspanin 2 |
| TUBA4B | tubulin, alpha 4b |
| WDR59 | WD repeat domain 59 |
| WISP3 | WNT1 inducible signaling pathway protein 3 |
| XRCC6 | X-ray repair complementing defective repair in Chinese hamster cells 6 |
| YOD1 | YOD1 deubiquitinase |
| ZNF76 | zinc finger protein 76 |
| Symbol | Name |
|---|---|
| ABI3BP | ABI family, member 3 (NESH) binding protein |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase |
| ALDOAP2 | aldolase A, fructose-bisphosphate pseudogene 2 |
| ANO2 | anoctamin 2, calcium activated chloride channel |
| ANXA2P3 | annexin A2 pseudogene 3 |
| APBB1IP | amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein |
| AVPI1 | arginine vasopressin-induced 1 |
| BHMT2 | betaine--homocysteine S-methyltransferase 2 |
| BTF3P11 | basic transcription factor 3 pseudogene 11 |
| C7ORF69 | chromosome 7 open reading frame 69 |
| CCDC85C | coiled-coil domain containing 85C |
| CD79B | CD79b molecule, immunoglobulin-associated beta |
| CD9 | CD9 molecule |
| CDK20 | cyclin-dependent kinase 20 |
| CELP | carboxyl ester lipase pseudogene |
| CHRNA10 | cholinergic receptor, nicotinic, alpha 10 (neuronal) |
| CLDN3 | claudin 3 |
| CLGN | calmegin |
| COPG2IT1 | COPG2 imprinted transcript 1 (non-protein coding) |
| CYSLTR1 | cysteinyl leukotriene receptor 1 |
| DAGLA | diacylglycerol lipase, alpha |
| EEF2KMT | eukaryotic elongation factor 2 lysine methyltransferase |
| ENTPD5 | ectonucleoside triphosphate diphosphohydrolase 5 |
| FAM106A | family with sequence similarity 106, member A |
| FGF23 | fibroblast growth factor 23 |
| FKBPL | FK506 binding protein like |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B |
| FRS3 | fibroblast growth factor receptor substrate 3 |
| GABRA4 | gamma-aminobutyric acid (GABA) A receptor, alpha 4 |
| GABRP | gamma-aminobutyric acid (GABA) A receptor, pi |
| GABRR2 | gamma-aminobutyric acid (GABA) A receptor, rho 2 |
| GLRA1 | glycine receptor, alpha 1 |
| GPC3 | glypican 3 |
| HHLA3 | HERV-H LTR-associating 3 |
| HIST1H2AJ | histone cluster 1, H2aj |
| HIST1H3G | histone cluster 1, H3g |
| HNRNPA3P1 | heterogeneous nuclear ribonucleoprotein A3 pseudogene 1 |
| HOXA2 | homeobox A2 |
| HOXA6 | homeobox A6 |
| HOXB9 | homeobox B9 |
| HOXC10 | homeobox C10 |
| HOXC8 | homeobox C8 |
| IBSP | integrin-binding sialoprotein |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 |
| IFT140 | intraflagellar transport 140 |
| IGH | immunoglobulin heavy locus |
| IRF7 | interferon regulatory factor 7 |
| ITGAX | integrin, alpha X (complement component 3 receptor 4 subunit) |
| KRT12 | keratin 12, type I |
| KRT20 | keratin 20, type I |
| KRT81 | keratin 81, type II |
| LIME1 | Lck interacting transmembrane adaptor 1 |
| LRP5 | low density lipoprotein receptor-related protein 5 |
| LTC4S | leukotriene C4 synthase |
| MBL1P | mannose-binding lectin (protein A) 1, pseudogene |
| MBTPS2 | membrane-bound transcription factor peptidase, site 2 |
| MED15 | mediator complex subunit 15 |
| NACA2 | nascent polypeptide-associated complex alpha subunit 2 |
| NAG18 | NAG18 mRNA |
| NAT6 | N-acetyltransferase 6 (GCN5-related) |
| NCS1 | neuronal calcium sensor 1 |
| NLGN1 | neuroligin 1 |
| NMUR1 | neuromedin U receptor 1 |
| NT5DC3 | 5'-nucleotidase domain containing 3 |
| OSBP2 | oxysterol binding protein 2 |
| PADI2 | peptidyl arginine deiminase, type II |
| PAK1 | p21 protein (Cdc42/Rac)-activated kinase 1 |
| PBOV1 | prostate and breast cancer overexpressed 1 |
| PCK1 | phosphoenolpyruvate carboxykinase 1 (soluble) |
| PLAT | plasminogen activator, tissue |
| PMFBP1 | polyamine modulated factor 1 binding protein 1 |
| POTEKP | POTE ankyrin domain family, member K, pseudogene |
| PPP1R2P9 | protein phosphatase 1, regulatory (inhibitor) subunit 2 pseudogene 9 |
| PRO2964 | uncharacterized protein PRO2964 |
| PSTPIP1 | proline-serine-threonine phosphatase interacting protein 1 |
| RAPGEFL1 | Rap guanine nucleotide exchange factor (GEF)-like 1 |
| RBM12B-AS1 | RBM12B antisense RNA 1 |
| RPL13P5 | ribosomal protein L13 pseudogene 5 |
| SCRT1 | scratch family zinc finger 1 |
| SCUBE3 | signal peptide, CUB domain, EGF-like 3 |
| SERINC5 | serine incorporator 5 |
| SFRP5 | secreted frizzled-related protein 5 |
| SH3GLB2 | SH3-domain GRB2-like endophilin B2 |
| SKA1 | spindle and kinetochore associated complex subunit 1 |
| SLC16A2 | solute carrier family 16, member 2 (thyroid hormone transporter) |
| SLC16A6 | solute carrier family 16, member 6 |
| SLC3A1 | solute carrier family 3 (amino acid transporter heavy chain), member 1 |
| SLC8B1 | solute carrier family 8 (sodium/lithium/calcium exchanger), member B1 |
| SMAD7 | SMAD family member 7 |
| SRD5A2 | steroid-5-alpha-reductase, alpha polypeptide 2 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 2) |
| SYTL2 | synaptotagmin-like 2 |
| TAS2R10 | taste receptor, type 2, member 10 |
| TINF2 | TERF1 (TRF1)-interacting nuclear factor 2 |
| TMEM140 | transmembrane protein 140 |
| TOM1 | target of myb1 (chicken) |
| TRPC5 | transient receptor potential cation channel, subfamily C, member 5 |
| ZNF282 | zinc finger protein 282 |
| ZNF385D | zinc finger protein 385D |