| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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193 genes differentially expressed following the theobromine-3334 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ACADS | acyl-CoA dehydrogenase, C-2 to C-3 short chain |
| ADRA1B | adrenoceptor alpha 1B |
| AKT2 | v-akt murine thymoma viral oncogene homolog 2 |
| APOBEC3C | apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3C |
| ARPIN | actin-related protein 2/3 complex inhibitor |
| ARR3 | arrestin 3, retinal (X-arrestin) |
| ASAP3 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 3 |
| BCL2L11 | BCL2-like 11 (apoptosis facilitator) |
| C1QTNF1 | C1q and tumor necrosis factor related protein 1 |
| CAMSAP1 | calmodulin regulated spectrin-associated protein 1 |
| CASP4 | caspase 4, apoptosis-related cysteine peptidase |
| CD1A | CD1a molecule |
| CD200 | CD200 molecule |
| CHRNA3 | cholinergic receptor, nicotinic, alpha 3 (neuronal) |
| CHST3 | carbohydrate (chondroitin 6) sulfotransferase 3 |
| CLSTN3 | calsyntenin 3 |
| COL1A1 | collagen, type I, alpha 1 |
| CORT | cortistatin |
| CSF1R | colony stimulating factor 1 receptor |
| CTIF | CBP80/20-dependent translation initiation factor |
| DEAF1 | DEAF1 transcription factor |
| DSC2 | desmocollin 2 |
| EGF | epidermal growth factor |
| EGR3 | early growth response 3 |
| EHMT1 | euchromatic histone-lysine N-methyltransferase 1 |
| FABP3 | fatty acid binding protein 3, muscle and heart |
| FAM155A | family with sequence similarity 155, member A |
| FCMR | Fc fragment of IgM receptor |
| FGF4 | fibroblast growth factor 4 |
| FOXG1 | forkhead box G1 |
| G3BP1 | GTPase activating protein (SH3 domain) binding protein 1 |
| GBP1 | guanylate binding protein 1, interferon-inducible |
| GNL3L | guanine nucleotide binding protein-like 3 (nucleolar)-like |
| GRM1 | glutamate receptor, metabotropic 1 |
| H6PD | hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase) |
| HBEGF | heparin-binding EGF-like growth factor |
| HECW1 | HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1 |
| HEG1 | heart development protein with EGF-like domains 1 |
| HRASLS2 | HRAS-like suppressor 2 |
| ICA1 | islet cell autoantigen 1, 69kDa |
| IGFBP5 | insulin-like growth factor binding protein 5 |
| IQGAP2 | IQ motif containing GTPase activating protein 2 |
| ITGB3 | integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 |
| KCNS1 | potassium voltage-gated channel, modifier subfamily S, member 1 |
| KDM8 | lysine (K)-specific demethylase 8 |
| KHDRBS1 | KH domain containing, RNA binding, signal transduction associated 1 |
| KIAA0125 | KIAA0125 |
| LRP12 | low density lipoprotein receptor-related protein 12 |
| MARK2 | MAP/microtubule affinity-regulating kinase 2 |
| MCAM | melanoma cell adhesion molecule |
| MEF2D | myocyte enhancer factor 2D |
| MMP17 | matrix metallopeptidase 17 (membrane-inserted) |
| MUC3B | mucin 3B, cell surface associated |
| MYBL1 | v-myb avian myeloblastosis viral oncogene homolog-like 1 |
| NAT6 | N-acetyltransferase 6 (GCN5-related) |
| NKX2-5 | NK2 homeobox 5 |
| NME5 | NME/NM23 family member 5 |
| OR2F1 | olfactory receptor, family 2, subfamily F, member 1 (gene/pseudogene) |
| OTOR | otoraplin |
| PADI3 | peptidyl arginine deiminase, type III |
| PCDH17 | protocadherin 17 |
| PCDHGA8 | protocadherin gamma subfamily A, 8 |
| PER1 | period circadian clock 1 |
| PHC3 | polyhomeotic homolog 3 (Drosophila) |
| PLSCR4 | phospholipid scramblase 4 |
| PODNL1 | podocan-like 1 |
| PRKCI | protein kinase C, iota |
| PSG5 | pregnancy specific beta-1-glycoprotein 5 |
| RAB40C | RAB40C, member RAS oncogene family |
| RFPL1S | RFPL1 antisense RNA 1 |
| RGS2 | regulator of G-protein signaling 2 |
| RIMS3 | regulating synaptic membrane exocytosis 3 |
| RND1 | Rho family GTPase 1 |
| RNF125 | ring finger protein 125, E3 ubiquitin protein ligase |
| SAYSD1 | SAYSVFN motif domain containing 1 |
| SCARA3 | scavenger receptor class A, member 3 |
| SGCB | sarcoglycan, beta (43kDa dystrophin-associated glycoprotein) |
| SH2D3A | SH2 domain containing 3A |
| SIPA1 | signal-induced proliferation-associated 1 |
| SLC1A2 | solute carrier family 1 (glial high affinity glutamate transporter), member 2 |
| SLC24A3 | solute carrier family 24 (sodium/potassium/calcium exchanger), member 3 |
| SOCS7 | suppressor of cytokine signaling 7 |
| SOX3 | SRY (sex determining region Y)-box 3 |
| SPPL2B | signal peptide peptidase like 2B |
| TAOK2 | TAO kinase 2 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) |
| TCF3 | transcription factor 3 |
| TCF7L1 | transcription factor 7-like 1 (T-cell specific, HMG-box) |
| TGM2 | transglutaminase 2 |
| TMEM63A | transmembrane protein 63A |
| TMPRSS3 | transmembrane protease, serine 3 |
| TRIM36 | tripartite motif containing 36 |
| TRO | trophinin |
| UHRF1BP1L | UHRF1 binding protein 1-like |
| USP46 | ubiquitin specific peptidase 46 |
| VIM | vimentin |
| ZNF350 | zinc finger protein 350 |
| ZNF589 | zinc finger protein 589 |
| Symbol | Name |
|---|---|
| ACTL8 | actin-like 8 |
| AFF4 | AF4/FMR2 family, member 4 |
| ALG12 | ALG12, alpha-1,6-mannosyltransferase |
| ANP32A-IT1 | ANP32A intronic transcript 1 |
| AP1G2 | adaptor-related protein complex 1, gamma 2 subunit |
| ARMCX2 | armadillo repeat containing, X-linked 2 |
| B3GNT2 | UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2 |
| BAHCC1 | BAH domain and coiled-coil containing 1 |
| C7ORF43 | chromosome 7 open reading frame 43 |
| CACNA2D2 | calcium channel, voltage-dependent, alpha 2/delta subunit 2 |
| CBL | Cbl proto-oncogene, E3 ubiquitin protein ligase |
| CBX8 | chromobox homolog 8 |
| CCBL1 | cysteine conjugate-beta lyase, cytoplasmic |
| CCNO | cyclin O |
| CD83 | CD83 molecule |
| CDK18 | cyclin-dependent kinase 18 |
| CENPO | centromere protein O |
| CSTA | cystatin A (stefin A) |
| CYP17A1 | cytochrome P450, family 17, subfamily A, polypeptide 1 |
| CYP26A1 | cytochrome P450, family 26, subfamily A, polypeptide 1 |
| CYP4B1 | cytochrome P450, family 4, subfamily B, polypeptide 1 |
| CYP4F12 | cytochrome P450, family 4, subfamily F, polypeptide 12 |
| DAPP1 | dual adaptor of phosphotyrosine and 3-phosphoinositides |
| DGKD | diacylglycerol kinase, delta 130kDa |
| DYSF | dysferlin |
| EFNA1 | ephrin-A1 |
| ENTPD7 | ectonucleoside triphosphate diphosphohydrolase 7 |
| FGL1 | fibrinogen-like 1 |
| FILIP1L | filamin A interacting protein 1-like |
| FKBP5 | FK506 binding protein 5 |
| FMO4 | flavin containing monooxygenase 4 |
| GAMT | guanidinoacetate N-methyltransferase |
| GDAP1 | ganglioside induced differentiation associated protein 1 |
| GLB1L | galactosidase, beta 1-like |
| GNB1L | guanine nucleotide binding protein (G protein), beta polypeptide 1-like |
| GNG13 | guanine nucleotide binding protein (G protein), gamma 13 |
| GNG3 | guanine nucleotide binding protein (G protein), gamma 3 |
| GRAMD4 | GRAM domain containing 4 |
| GSTM2 | glutathione S-transferase mu 2 (muscle) |
| H1F0 | H1 histone family, member 0 |
| HCAR3 | hydroxycarboxylic acid receptor 3 |
| HDAC7 | histone deacetylase 7 |
| HIST1H2AJ | histone cluster 1, H2aj |
| HIST1H4F | histone cluster 1, H4f |
| HPN | hepsin |
| HYI | hydroxypyruvate isomerase (putative) |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein |
| IL22 | interleukin 22 |
| INO80D | INO80 complex subunit D |
| KANSL1L | KAT8 regulatory NSL complex subunit 1-like |
| KCNK12 | potassium channel, two pore domain subfamily K, member 12 |
| KIAA0319L | KIAA0319-like |
| LRP2 | low density lipoprotein receptor-related protein 2 |
| LY6D | lymphocyte antigen 6 complex, locus D |
| MAGEA6 | melanoma antigen family A6 |
| MB | myoglobin |
| MRM1 | mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae) |
| MXD3 | MAX dimerization protein 3 |
| MYO1E | myosin IE |
| MYO1F | myosin IF |
| MYOZ3 | myozenin 3 |
| NPM3 | nucleophosmin/nucleoplasmin 3 |
| OPA3 | optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia) |
| PCDHB8 | protocadherin beta 8 |
| PITPNM1 | phosphatidylinositol transfer protein, membrane-associated 1 |
| PLA2G4C | phospholipase A2, group IVC (cytosolic, calcium-independent) |
| PRR14L | proline rich 14-like |
| PVRL2 | poliovirus receptor-related 2 (herpesvirus entry mediator B) |
| RETSAT | retinol saturase (all-trans-retinol 13,14-reductase) |
| RPAIN | RPA interacting protein |
| RPL13P5 | ribosomal protein L13 pseudogene 5 |
| RRAGB | Ras-related GTP binding B |
| RUNDC3B | RUN domain containing 3B |
| S100A9 | S100 calcium binding protein A9 |
| SCAI | suppressor of cancer cell invasion |
| SH3TC1 | SH3 domain and tetratricopeptide repeats 1 |
| SKIL | SKI-like proto-oncogene |
| SPTBN2 | spectrin, beta, non-erythrocytic 2 |
| SREK1IP1 | SREK1-interacting protein 1 |
| STON1 | stonin 1 |
| TH | tyrosine hydroxylase |
| THRB | thyroid hormone receptor, beta |
| TMEM53 | transmembrane protein 53 |
| TNFRSF11A | tumor necrosis factor receptor superfamily, member 11a, NFKB activator |
| TRAIP | TRAF interacting protein |
| TRIM5 | tripartite motif containing 5 |
| TSGA10 | testis specific, 10 |
| UPP1 | uridine phosphorylase 1 |
| USB1 | U6 snRNA biogenesis 1 |
| USP19 | ubiquitin specific peptidase 19 |
| ZBTB44 | zinc finger and BTB domain containing 44 |
| ZBTB6 | zinc finger and BTB domain containing 6 |
| ZNF358 | zinc finger protein 358 |
| ZSCAN26 | zinc finger and SCAN domain containing 26 |