| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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194 genes differentially expressed following the theobromine-6613 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ACTG2 | actin, gamma 2, smooth muscle, enteric |
| ADAMTS13 | ADAM metallopeptidase with thrombospondin type 1 motif, 13 |
| ADRA2C | adrenoceptor alpha 2C |
| AHSP | alpha hemoglobin stabilizing protein |
| AIM1L | absent in melanoma 1-like |
| ANGPTL2 | angiopoietin-like 2 |
| ANP32A-IT1 | ANP32A intronic transcript 1 |
| ARHGAP33 | Rho GTPase activating protein 33 |
| ARHGAP44 | Rho GTPase activating protein 44 |
| ARHGEF11 | Rho guanine nucleotide exchange factor (GEF) 11 |
| ASB1 | ankyrin repeat and SOCS box containing 1 |
| ATP10A | ATPase, class V, type 10A |
| BAZ1B | bromodomain adjacent to zinc finger domain, 1B |
| BMP2 | bone morphogenetic protein 2 |
| C8A | complement component 8, alpha polypeptide |
| CACNB1 | calcium channel, voltage-dependent, beta 1 subunit |
| CALHM2 | calcium homeostasis modulator 2 |
| CCDC132 | coiled-coil domain containing 132 |
| CDK6 | cyclin-dependent kinase 6 |
| CHRDL1 | chordin-like 1 |
| CHRNB2 | cholinergic receptor, nicotinic, beta 2 (neuronal) |
| COL17A1 | collagen, type XVII, alpha 1 |
| CST4 | cystatin S |
| CTNNA3 | catenin (cadherin-associated protein), alpha 3 |
| DOCK5 | dedicator of cytokinesis 5 |
| DPY19L1P1 | DPY19L1 pseudogene 1 |
| DVL2 | dishevelled segment polarity protein 2 |
| EMC3 | ER membrane protein complex subunit 3 |
| EML2 | echinoderm microtubule associated protein like 2 |
| ESR1 | estrogen receptor 1 |
| ESRRG | estrogen-related receptor gamma |
| FAM46C | family with sequence similarity 46, member C |
| FAM50B | family with sequence similarity 50, member B |
| FGFR2 | fibroblast growth factor receptor 2 |
| FLI1 | Fli-1 proto-oncogene, ETS transcription factor |
| FOXO4 | forkhead box O4 |
| GALNT14 | polypeptide N-acetylgalactosaminyltransferase 14 |
| HFE | hemochromatosis |
| HIRA | histone cell cycle regulator |
| HMOX1 | heme oxygenase 1 |
| HNRNPA3P1 | heterogeneous nuclear ribonucleoprotein A3 pseudogene 1 |
| ICAM1 | intercellular adhesion molecule 1 |
| IL24 | interleukin 24 |
| KANSL1L | KAT8 regulatory NSL complex subunit 1-like |
| KCNAB1 | potassium channel, voltage gated subfamily A regulatory beta subunit 1 |
| KIAA0040 | KIAA0040 |
| KIFC3 | kinesin family member C3 |
| KLHL25 | kelch-like family member 25 |
| LLGL1 | lethal giant larvae homolog 1 (Drosophila) |
| METTL7A | methyltransferase like 7A |
| MMP7 | matrix metallopeptidase 7 |
| MOCS3 | molybdenum cofactor synthesis 3 |
| NOVA2 | neuro-oncological ventral antigen 2 |
| NPY6R | neuropeptide Y receptor Y6 (pseudogene) |
| NR2E3 | nuclear receptor subfamily 2, group E, member 3 |
| NRTN | neurturin |
| OSBPL10 | oxysterol binding protein-like 10 |
| OSGIN1 | oxidative stress induced growth inhibitor 1 |
| PAPOLG | poly(A) polymerase gamma |
| PCDH9 | protocadherin 9 |
| PENK | proenkephalin |
| PIP5K1A | phosphatidylinositol-4-phosphate 5-kinase, type I, alpha |
| PITX1 | paired-like homeodomain 1 |
| POU2F2 | POU class 2 homeobox 2 |
| PRDM1 | PR domain containing 1, with ZNF domain |
| PSD4 | pleckstrin and Sec7 domain containing 4 |
| PTPN21 | protein tyrosine phosphatase, non-receptor type 21 |
| PTPRB | protein tyrosine phosphatase, receptor type, B |
| RAB31 | RAB31, member RAS oncogene family |
| RAD23B | RAD23 homolog B (S. cerevisiae) |
| RASAL2 | RAS protein activator like 2 |
| REEP2 | receptor accessory protein 2 |
| RGS4 | regulator of G-protein signaling 4 |
| RHBDD3 | rhomboid domain containing 3 |
| RNF122 | ring finger protein 122 |
| RPL35A | ribosomal protein L35a |
| SAMD4A | sterile alpha motif domain containing 4A |
| SIRT4 | sirtuin 4 |
| SLC11A1 | solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1 |
| SLC17A7 | solute carrier family 17 (vesicular glutamate transporter), member 7 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 |
| SLC9A7 | solute carrier family 9, subfamily A (NHE7, cation proton antiporter 7), member 7 |
| SMG7 | SMG7 nonsense mediated mRNA decay factor |
| SOGA1 | suppressor of glucose, autophagy associated 1 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like |
| SPSB3 | splA/ryanodine receptor domain and SOCS box containing 3 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 |
| STAB1 | stabilin 1 |
| STK24 | serine/threonine kinase 24 |
| STS | steroid sulfatase (microsomal), isozyme S |
| TADA3 | transcriptional adaptor 3 |
| THOC5 | THO complex 5 |
| TNIK | TRAF2 and NCK interacting kinase |
| TNKS2 | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2 |
| TSPAN7 | tetraspanin 7 |
| VN1R1 | vomeronasal 1 receptor 1 |
| ZC3H7B | zinc finger CCCH-type containing 7B |
| ZER1 | zyg-11 related, cell cycle regulator |
| ZNF24 | zinc finger protein 24 |
| Symbol | Name |
|---|---|
| ABCB8 | ATP-binding cassette, sub-family B (MDR/TAP), member 8 |
| ACADS | acyl-CoA dehydrogenase, C-2 to C-3 short chain |
| ADTRP | androgen-dependent TFPI-regulating protein |
| ARHGEF16 | Rho guanine nucleotide exchange factor (GEF) 16 |
| ARID3B | AT rich interactive domain 3B (BRIGHT-like) |
| ARMCX2 | armadillo repeat containing, X-linked 2 |
| C1ORF105 | chromosome 1 open reading frame 105 |
| C9ORF9 | chromosome 9 open reading frame 9 |
| CBX4 | chromobox homolog 4 |
| CCDC85C | coiled-coil domain containing 85C |
| CCT6B | chaperonin containing TCP1, subunit 6B (zeta 2) |
| CENPO | centromere protein O |
| CIDEC | cell death-inducing DFFA-like effector c |
| CLEC16A | C-type lectin domain family 16, member A |
| CNN2 | calponin 2 |
| CSF1R | colony stimulating factor 1 receptor |
| CTSD | cathepsin D |
| CYP2J2 | cytochrome P450, family 2, subfamily J, polypeptide 2 |
| CYP2R1 | cytochrome P450, family 2, subfamily R, polypeptide 1 |
| DBNDD1 | dysbindin (dystrobrevin binding protein 1) domain containing 1 |
| DBR1 | debranching RNA lariats 1 |
| DLK2 | delta-like 2 homolog (Drosophila) |
| DNAH17 | dynein, axonemal, heavy chain 17 |
| ERCC4 | excision repair cross-complementation group 4 |
| ERMAP | erythroblast membrane-associated protein (Scianna blood group) |
| ERN2 | endoplasmic reticulum to nucleus signaling 2 |
| FAM120C | family with sequence similarity 120C |
| FAM222B | family with sequence similarity 222, member B |
| FBXO40 | F-box protein 40 |
| FSTL3 | follistatin-like 3 (secreted glycoprotein) |
| GABRR2 | gamma-aminobutyric acid (GABA) A receptor, rho 2 |
| GALK1 | galactokinase 1 |
| GAMT | guanidinoacetate N-methyltransferase |
| GRAMD1C | GRAM domain containing 1C |
| GTPBP2 | GTP binding protein 2 |
| HDAC11 | histone deacetylase 11 |
| HDAC7 | histone deacetylase 7 |
| HINFP | histone H4 transcription factor |
| HIST1H1D | histone cluster 1, H1d |
| HIST1H2BN | histone cluster 1, H2bn |
| HOXA4 | homeobox A4 |
| HSD17B14 | hydroxysteroid (17-beta) dehydrogenase 14 |
| IL12B | interleukin 12B |
| IQCC | IQ motif containing C |
| IQSEC2 | IQ motif and Sec7 domain 2 |
| ITGB2 | integrin, beta 2 (complement component 3 receptor 3 and 4 subunit) |
| ITPKC | inositol-trisphosphate 3-kinase C |
| KIAA0319L | KIAA0319-like |
| KIAA1456 | KIAA1456 |
| KIAA1462 | KIAA1462 |
| KLHL26 | kelch-like family member 26 |
| LAX1 | lymphocyte transmembrane adaptor 1 |
| LSR | lipolysis stimulated lipoprotein receptor |
| MBL1P | mannose-binding lectin (protein A) 1, pseudogene |
| MCC | mutated in colorectal cancers |
| ME3 | malic enzyme 3, NADP(+)-dependent, mitochondrial |
| MFGE8 | milk fat globule-EGF factor 8 protein |
| MYO1F | myosin IF |
| NABP1 | nucleic acid binding protein 1 |
| NPFFR1 | neuropeptide FF receptor 1 |
| NUP62CL | nucleoporin 62kDa C-terminal like |
| PDE6B | phosphodiesterase 6B, cGMP-specific, rod, beta |
| PICK1 | protein interacting with PRKCA 1 |
| PLCG2 | phospholipase C, gamma 2 (phosphatidylinositol-specific) |
| PLEKHB1 | pleckstrin homology domain containing, family B (evectins) member 1 |
| PLEKHO1 | pleckstrin homology domain containing, family O member 1 |
| PPP2R3B | protein phosphatase 2, regulatory subunit B'', beta |
| PTPRE | protein tyrosine phosphatase, receptor type, E |
| RNF31 | ring finger protein 31 |
| RPGRIP1L | RPGRIP1-like |
| S100A3 | S100 calcium binding protein A3 |
| SAYSD1 | SAYSVFN motif domain containing 1 |
| SLC14A1 | solute carrier family 14 (urea transporter), member 1 (Kidd blood group) |
| SLC29A2 | solute carrier family 29 (equilibrative nucleoside transporter), member 2 |
| SLC39A7 | solute carrier family 39 (zinc transporter), member 7 |
| SPRYD7 | SPRY domain containing 7 |
| ST6GALNAC2 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 |
| STAG3L4 | stromal antigen 3-like 4 (pseudogene) |
| TBC1D17 | TBC1 domain family, member 17 |
| TINAGL1 | tubulointerstitial nephritis antigen-like 1 |
| TMEM212 | transmembrane protein 212 |
| TOLLIP | toll interacting protein |
| TPCN1 | two pore segment channel 1 |
| TRPC5 | transient receptor potential cation channel, subfamily C, member 5 |
| TTN | titin |
| TUBB2B | tubulin, beta 2B class IIb |
| TXLNG | taxilin gamma |
| USB1 | U6 snRNA biogenesis 1 |
| USP18 | ubiquitin specific peptidase 18 |
| WDR62 | WD repeat domain 62 |
| ZBTB22 | zinc finger and BTB domain containing 22 |
| ZNF137P | zinc finger protein 137, pseudogene |
| ZNF37BP | zinc finger protein 37B, pseudogene |
| ZNF711 | zinc finger protein 711 |
| ZNF747 | zinc finger protein 747 |
