| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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194 genes differentially expressed following the theophylline-2986 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ACOXL | acyl-CoA oxidase-like |
| AMFR | autocrine motility factor receptor, E3 ubiquitin protein ligase |
| ARL2BP | ADP-ribosylation factor-like 2 binding protein |
| ARMC4 | armadillo repeat containing 4 |
| ATG10 | autophagy related 10 |
| BRF1 | BRF1, RNA polymerase III transcription initiation factor 90 kDa subunit |
| BTD | biotinidase |
| C9ORF9 | chromosome 9 open reading frame 9 |
| CACTIN | cactin, spliceosome C complex subunit |
| CCL19 | chemokine (C-C motif) ligand 19 |
| CD22 | CD22 molecule |
| CDHR5 | cadherin-related family member 5 |
| CEACAM7 | carcinoembryonic antigen-related cell adhesion molecule 7 |
| CHMP6 | charged multivesicular body protein 6 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 |
| DAPK2 | death-associated protein kinase 2 |
| DCHS2 | dachsous cadherin-related 2 |
| DDAH2 | dimethylarginine dimethylaminohydrolase 2 |
| DNASE1L3 | deoxyribonuclease I-like 3 |
| DOC2A | double C2-like domains, alpha |
| DOCK6 | dedicator of cytokinesis 6 |
| EGLN3 | egl-9 family hypoxia-inducible factor 3 |
| EGR4 | early growth response 4 |
| EHD2 | EH-domain containing 2 |
| ENOX2 | ecto-NOX disulfide-thiol exchanger 2 |
| ESR2 | estrogen receptor 2 (ER beta) |
| EXO5 | exonuclease 5 |
| EXOG | endo/exonuclease (5'-3'), endonuclease G-like |
| FARP1 | FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived) |
| FDPS | farnesyl diphosphate synthase |
| FHL1 | four and a half LIM domains 1 |
| FLRT3 | fibronectin leucine rich transmembrane protein 3 |
| FOXO1 | forkhead box O1 |
| FXYD3 | FXYD domain containing ion transport regulator 3 |
| GNG7 | guanine nucleotide binding protein (G protein), gamma 7 |
| GRM8 | glutamate receptor, metabotropic 8 |
| GTF2A1 | general transcription factor IIA, 1, 19/37kDa |
| HAB1 | B1 for mucin |
| HRH3 | histamine receptor H3 |
| HUS1 | HUS1 checkpoint homolog (S. pombe) |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 |
| IL4 | interleukin 4 |
| IL6R | interleukin 6 receptor |
| INF2 | inverted formin, FH2 and WH2 domain containing |
| KANSL1L | KAT8 regulatory NSL complex subunit 1-like |
| KRT23 | keratin 23, type I |
| KRT83 | keratin 83, type II |
| KYNU | kynureninase |
| LOC257152 | uncharacterized LOC257152 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 |
| MAML3 | mastermind-like 3 (Drosophila) |
| MAST2 | microtubule associated serine/threonine kinase 2 |
| MYLK | myosin light chain kinase |
| NRP1 | neuropilin 1 |
| OBSCN | obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF |
| PCDH11Y | protocadherin 11 Y-linked |
| PDE11A | phosphodiesterase 11A |
| PIGO | phosphatidylinositol glycan anchor biosynthesis, class O |
| PMS2P3 | postmeiotic segregation increased 2 pseudogene 3 |
| PRAMEF11 | PRAME family member 11 |
| PTTG2 | pituitary tumor-transforming 2 |
| RAB11B | RAB11B, member RAS oncogene family |
| RALGAPA1 | Ral GTPase activating protein, alpha subunit 1 (catalytic) |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 |
| RBBP9 | retinoblastoma binding protein 9 |
| RGS12 | regulator of G-protein signaling 12 |
| RHEB | Ras homolog enriched in brain |
| RHO | rhodopsin |
| RPL10L | ribosomal protein L10-like |
| SMC1A | structural maintenance of chromosomes 1A |
| SPDEF | SAM pointed domain containing ETS transcription factor |
| SSPN | sarcospan |
| ST3GAL4 | ST3 beta-galactoside alpha-2,3-sialyltransferase 4 |
| ST8SIA4 | ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4 |
| STRN | striatin, calmodulin binding protein |
| STRN3 | striatin, calmodulin binding protein 3 |
| STS | steroid sulfatase (microsomal), isozyme S |
| SYNM | synemin, intermediate filament protein |
| TAPT1 | transmembrane anterior posterior transformation 1 |
| TEAD3 | TEA domain family member 3 |
| TIMELESS | timeless circadian clock |
| TMPRSS2 | transmembrane protease, serine 2 |
| TNFRSF9 | tumor necrosis factor receptor superfamily, member 9 |
| TRPS1 | trichorhinophalangeal syndrome I |
| TTC4 | tetratricopeptide repeat domain 4 |
| UTP18 | UTP18 small subunit (SSU) processome component homolog (yeast) |
| VAMP2 | vesicle-associated membrane protein 2 (synaptobrevin 2) |
| VAMP5 | vesicle-associated membrane protein 5 |
| VAX2 | ventral anterior homeobox 2 |
| VCX2 | variable charge, X-linked 2 |
| WIPI2 | WD repeat domain, phosphoinositide interacting 2 |
| WISP3 | WNT1 inducible signaling pathway protein 3 |
| ZBTB17 | zinc finger and BTB domain containing 17 |
| ZBTB20 | zinc finger and BTB domain containing 20 |
| ZNF235 | zinc finger protein 235 |
| Symbol | Name |
|---|---|
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase |
| ACADSB | acyl-CoA dehydrogenase, short/branched chain |
| ACTR8 | ARP8 actin-related protein 8 homolog (yeast) |
| ADGRD2 | adhesion G protein-coupled receptor D2 |
| AP1G2 | adaptor-related protein complex 1, gamma 2 subunit |
| ARL15 | ADP-ribosylation factor-like 15 |
| C5AR1 | complement component 5a receptor 1 |
| CCDC85C | coiled-coil domain containing 85C |
| CCL4 | chemokine (C-C motif) ligand 4 |
| CDKL1 | cyclin-dependent kinase-like 1 (CDC2-related kinase) |
| CDKL3 | cyclin-dependent kinase-like 3 |
| CEP72 | centrosomal protein 72kDa |
| CFAP45 | cilia and flagella associated protein 45 |
| CHST4 | carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 4 |
| COQ6 | coenzyme Q6 monooxygenase |
| CRELD1 | cysteine-rich with EGF-like domains 1 |
| CTSV | cathepsin V |
| CYP4F8 | cytochrome P450, family 4, subfamily F, polypeptide 8 |
| DDX54 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 54 |
| EBF2 | early B-cell factor 2 |
| ETV4 | ets variant 4 |
| FAM63A | family with sequence similarity 63, member A |
| FBXL7 | F-box and leucine-rich repeat protein 7 |
| FGF23 | fibroblast growth factor 23 |
| FURIN | furin (paired basic amino acid cleaving enzyme) |
| GABRA2 | gamma-aminobutyric acid (GABA) A receptor, alpha 2 |
| GABRP | gamma-aminobutyric acid (GABA) A receptor, pi |
| GABRR2 | gamma-aminobutyric acid (GABA) A receptor, rho 2 |
| GBP2 | guanylate binding protein 2, interferon-inducible |
| GJA1 | gap junction protein, alpha 1, 43kDa |
| GNG4 | guanine nucleotide binding protein (G protein), gamma 4 |
| GNRH1 | gonadotropin-releasing hormone 1 (luteinizing-releasing hormone) |
| HIST1H1D | histone cluster 1, H1d |
| HOXC10 | homeobox C10 |
| HSPB6 | heat shock protein, alpha-crystallin-related, B6 |
| IBSP | integrin-binding sialoprotein |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 |
| IFNAR1 | interferon (alpha, beta and omega) receptor 1 |
| IFT22 | intraflagellar transport 22 |
| IL12B | interleukin 12B |
| IL2 | interleukin 2 |
| KDM8 | lysine (K)-specific demethylase 8 |
| KIF17 | kinesin family member 17 |
| LEFTY2 | left-right determination factor 2 |
| LENEP | lens epithelial protein |
| LINC00260 | long intergenic non-protein coding RNA 260 |
| LRRC20 | leucine rich repeat containing 20 |
| LTA | lymphotoxin alpha |
| MAGOH2P | mago-nashi homolog 2, pseudogene |
| MAP1S | microtubule-associated protein 1S |
| MBNL3 | muscleblind-like splicing regulator 3 |
| MINOS1P1 | mitochondrial inner membrane organizing system 1 pseudogene 1 |
| MYH4 | myosin, heavy chain 4, skeletal muscle |
| NINJ2 | ninjurin 2 |
| NMUR1 | neuromedin U receptor 1 |
| NT5DC3 | 5'-nucleotidase domain containing 3 |
| P2RX5 | purinergic receptor P2X, ligand gated ion channel, 5 |
| PCBP4 | poly(rC) binding protein 4 |
| PDE6C | phosphodiesterase 6C, cGMP-specific, cone, alpha prime |
| PDE7B | phosphodiesterase 7B |
| PDGFRL | platelet-derived growth factor receptor-like |
| PFN2 | profilin 2 |
| PGP | phosphoglycolate phosphatase |
| PLA2G1B | phospholipase A2, group IB (pancreas) |
| PLA2G3 | phospholipase A2, group III |
| PLA2G7 | phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma) |
| PLEKHS1 | pleckstrin homology domain containing, family S member 1 |
| PRDM12 | PR domain containing 12 |
| PYGB | phosphorylase, glycogen; brain |
| RAB3A | RAB3A, member RAS oncogene family |
| RAC3 | ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3) |
| S1PR4 | sphingosine-1-phosphate receptor 4 |
| SCN5A | sodium channel, voltage gated, type V alpha subunit |
| SCRT1 | scratch family zinc finger 1 |
| SFRP5 | secreted frizzled-related protein 5 |
| SIT1 | signaling threshold regulating transmembrane adaptor 1 |
| SLC10A3 | solute carrier family 10, member 3 |
| SLC16A2 | solute carrier family 16, member 2 (thyroid hormone transporter) |
| SNAI1 | snail family zinc finger 1 |
| SPATA2L | spermatogenesis associated 2-like |
| STAG3L4 | stromal antigen 3-like 4 (pseudogene) |
| STATH | statherin |
| STX1A | syntaxin 1A (brain) |
| SV2A | synaptic vesicle glycoprotein 2A |
| SYNDIG1 | synapse differentiation inducing 1 |
| TCTA | T-cell leukemia translocation altered |
| TMEM180 | transmembrane protein 180 |
| TMEM209 | transmembrane protein 209 |
| TNNT1 | troponin T type 1 (skeletal, slow) |
| TRPV1 | transient receptor potential cation channel, subfamily V, member 1 |
| TUFT1 | tuftelin 1 |
| VNN2 | vanin 2 |
| VPREB1 | pre-B lymphocyte 1 |
| VPS33A | vacuolar protein sorting 33 homolog A (S. cerevisiae) |
| YPEL1 | yippee-like 1 (Drosophila) |
| ZNF215 | zinc finger protein 215 |
| ZNF354A | zinc finger protein 354A |
| ZNF415 | zinc finger protein 415 |
| ZNF675 | zinc finger protein 675 |
