| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
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195 genes differentially expressed following the theophylline-3326 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ADRBK1 | adrenergic, beta, receptor kinase 1 |
| AGAP2 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 2 |
| AKT2 | v-akt murine thymoma viral oncogene homolog 2 |
| ALDH1L1 | aldehyde dehydrogenase 1 family, member L1 |
| APOLD1 | apolipoprotein L domain containing 1 |
| ARHGAP26 | Rho GTPase activating protein 26 |
| ARID1A | AT rich interactive domain 1A (SWI-like) |
| BCORL1 | BCL6 corepressor-like 1 |
| CACNB1 | calcium channel, voltage-dependent, beta 1 subunit |
| CALB1 | calbindin 1, 28kDa |
| CCL27 | chemokine (C-C motif) ligand 27 |
| CCL7 | chemokine (C-C motif) ligand 7 |
| CD6 | CD6 molecule |
| CDRT1 | CMT1A duplicated region transcript 1 |
| CEP295 | centrosomal protein 295kDa |
| CRH | corticotropin releasing hormone |
| CYP3A5 | cytochrome P450, family 3, subfamily A, polypeptide 5 |
| DHRS7 | dehydrogenase/reductase (SDR family) member 7 |
| DNAJA4 | DnaJ (Hsp40) homolog, subfamily A, member 4 |
| DRD2 | dopamine receptor D2 |
| ELL | elongation factor RNA polymerase II |
| ELL2 | elongation factor, RNA polymerase II, 2 |
| F5 | coagulation factor V (proaccelerin, labile factor) |
| FBXO21 | F-box protein 21 |
| FBXO40 | F-box protein 40 |
| FBXO41 | F-box protein 41 |
| FCGR2C | Fc fragment of IgG, low affinity IIc, receptor for (CD32) (gene/pseudogene) |
| GABBR2 | gamma-aminobutyric acid (GABA) B receptor, 2 |
| GAD1 | glutamate decarboxylase 1 (brain, 67kDa) |
| GNAO1 | guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O |
| GNAT2 | guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 2 |
| HAND1 | heart and neural crest derivatives expressed 1 |
| HFE | hemochromatosis |
| HIST1H2BE | histone cluster 1, H2be |
| HOXA6 | homeobox A6 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase |
| IGHG1 | immunoglobulin heavy constant gamma 1 (G1m marker) |
| IL17RC | interleukin 17 receptor C |
| IL1R2 | interleukin 1 receptor, type II |
| IL2RG | interleukin 2 receptor, gamma |
| INO80D | INO80 complex subunit D |
| ITGA9 | integrin, alpha 9 |
| JAG1 | jagged 1 |
| KCNJ8 | potassium channel, inwardly rectifying subfamily J, member 8 |
| KITLG | KIT ligand |
| KLHDC8A | kelch domain containing 8A |
| LGALS9 | lectin, galactoside-binding, soluble, 9 |
| LRCH4 | leucine-rich repeats and calponin homology (CH) domain containing 4 |
| MAPK8IP1 | mitogen-activated protein kinase 8 interacting protein 1 |
| MYL4 | myosin, light chain 4, alkali; atrial, embryonic |
| NDN | necdin, melanoma antigen (MAGE) family member |
| NEUROD4 | neuronal differentiation 4 |
| OR7A10 | olfactory receptor, family 7, subfamily A, member 10 |
| PARD6B | par-6 family cell polarity regulator beta |
| PARG | poly (ADP-ribose) glycohydrolase |
| PCDH1 | protocadherin 1 |
| PDE4B | phosphodiesterase 4B, cAMP-specific |
| PDLIM4 | PDZ and LIM domain 4 |
| PHF20L1 | PHD finger protein 20-like 1 |
| PIN1P1 | peptidylprolyl cis/trans isomerase, NIMA-interacting 1 pseudogene 1 |
| PODNL1 | podocan-like 1 |
| POMT2 | protein-O-mannosyltransferase 2 |
| PPP2R1B | protein phosphatase 2, regulatory subunit A, beta |
| PRB3 | proline-rich protein BstNI subfamily 3 |
| PRKCI | protein kinase C, iota |
| PRLR | prolactin receptor |
| PVR | poliovirus receptor |
| PVRL3 | poliovirus receptor-related 3 |
| RGS10 | regulator of G-protein signaling 10 |
| RMND5A | required for meiotic nuclear division 5 homolog A (S. cerevisiae) |
| RPL10 | ribosomal protein L10 |
| RUFY3 | RUN and FYVE domain containing 3 |
| RUNDC3A | RUN domain containing 3A |
| SEMA6D | sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D |
| SIGLEC7 | sialic acid binding Ig-like lectin 7 |
| SLC15A1 | solute carrier family 15 (oligopeptide transporter), member 1 |
| SLC39A9 | solute carrier family 39, member 9 |
| SPAG8 | sperm associated antigen 8 |
| SUGP1 | SURP and G patch domain containing 1 |
| SVEP1 | sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1 |
| SYT2 | synaptotagmin II |
| TAOK2 | TAO kinase 2 |
| TBL2 | transducin (beta)-like 2 |
| TEX40 | testis expressed 40 |
| TMPRSS15 | transmembrane protease, serine 15 |
| TSPAN2 | tetraspanin 2 |
| TYRO3 | TYRO3 protein tyrosine kinase |
| UBA7 | ubiquitin-like modifier activating enzyme 7 |
| UPK3A | uroplakin 3A |
| USH1C | Usher syndrome 1C (autosomal recessive, severe) |
| VDR | vitamin D (1,25- dihydroxyvitamin D3) receptor |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) |
| XIAP | X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase |
| ZBTB33 | zinc finger and BTB domain containing 33 |
| ZNF639 | zinc finger protein 639 |
| ZNF76 | zinc finger protein 76 |
| ZSCAN12 | zinc finger and SCAN domain containing 12 |
| ZZEF1 | zinc finger, ZZ-type with EF-hand domain 1 |
| Symbol | Name |
|---|---|
| AFF4 | AF4/FMR2 family, member 4 |
| AKIP1 | A kinase (PRKA) interacting protein 1 |
| ALPK1 | alpha-kinase 1 |
| ANP32A-IT1 | ANP32A intronic transcript 1 |
| APLP1 | amyloid beta (A4) precursor-like protein 1 |
| ARL15 | ADP-ribosylation factor-like 15 |
| ASIC3 | acid sensing (proton gated) ion channel 3 |
| B3GNT3 | UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3 |
| B3GNT4 | UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 4 |
| BAHD1 | bromo adjacent homology domain containing 1 |
| BRD9 | bromodomain containing 9 |
| BTBD2 | BTB (POZ) domain containing 2 |
| C1ORF105 | chromosome 1 open reading frame 105 |
| CA4 | carbonic anhydrase IV |
| CACNA1H | calcium channel, voltage-dependent, T type, alpha 1H subunit |
| CASP3 | caspase 3, apoptosis-related cysteine peptidase |
| CBX8 | chromobox homolog 8 |
| CCP110 | centriolar coiled coil protein 110kDa |
| CORO7 | coronin 7 |
| CYP4F12 | cytochrome P450, family 4, subfamily F, polypeptide 12 |
| DAPP1 | dual adaptor of phosphotyrosine and 3-phosphoinositides |
| DCAF4 | DDB1 and CUL4 associated factor 4 |
| DSCAM | Down syndrome cell adhesion molecule |
| ERMAP | erythroblast membrane-associated protein (Scianna blood group) |
| FBXO22 | F-box protein 22 |
| FER | fer (fps/fes related) tyrosine kinase |
| GEMIN8 | gem (nuclear organelle) associated protein 8 |
| GFI1 | growth factor independent 1 transcription repressor |
| GLB1L | galactosidase, beta 1-like |
| GNG4 | guanine nucleotide binding protein (G protein), gamma 4 |
| GPRC5C | G protein-coupled receptor, class C, group 5, member C |
| GRAMD1C | GRAM domain containing 1C |
| GUSBP3 | glucuronidase, beta pseudogene 3 |
| HDAC7 | histone deacetylase 7 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 |
| HSD17B14 | hydroxysteroid (17-beta) dehydrogenase 14 |
| HYI | hydroxypyruvate isomerase (putative) |
| IL22 | interleukin 22 |
| IQSEC2 | IQ motif and Sec7 domain 2 |
| IRF1 | interferon regulatory factor 1 |
| IRF9 | interferon regulatory factor 9 |
| JMJD4 | jumonji domain containing 4 |
| KANSL1L | KAT8 regulatory NSL complex subunit 1-like |
| KAT2A | K(lysine) acetyltransferase 2A |
| KCNK12 | potassium channel, two pore domain subfamily K, member 12 |
| KIAA1107 | KIAA1107 |
| LHX1 | LIM homeobox 1 |
| LRP3 | low density lipoprotein receptor-related protein 3 |
| LZTS3 | leucine zipper, putative tumor suppressor family member 3 |
| MAP1S | microtubule-associated protein 1S |
| MFAP2 | microfibrillar-associated protein 2 |
| MOCS3 | molybdenum cofactor synthesis 3 |
| MTCP1 | mature T-cell proliferation 1 |
| MTMR6 | myotubularin related protein 6 |
| MUM1 | melanoma associated antigen (mutated) 1 |
| MXD3 | MAX dimerization protein 3 |
| NPIPB15 | nuclear pore complex interacting protein family, member B15 |
| NPTX1 | neuronal pentraxin I |
| PAIP2B | poly(A) binding protein interacting protein 2B |
| PCDHB13 | protocadherin beta 13 |
| PCDHGB5 | protocadherin gamma subfamily B, 5 |
| PGPEP1 | pyroglutamyl-peptidase I |
| PHEX | phosphate regulating endopeptidase homolog, X-linked |
| PLEKHM2 | pleckstrin homology domain containing, family M (with RUN domain) member 2 |
| PRODH | proline dehydrogenase (oxidase) 1 |
| RAC3 | ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3) |
| RNF170 | ring finger protein 170 |
| RPL10L | ribosomal protein L10-like |
| SCGB2A2 | secretoglobin, family 2A, member 2 |
| SCN1B | sodium channel, voltage gated, type I beta subunit |
| SCUBE2 | signal peptide, CUB domain, EGF-like 2 |
| SEMA4A | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A |
| SGCG | sarcoglycan, gamma (35kDa dystrophin-associated glycoprotein) |
| SLC12A6 | solute carrier family 12 (potassium/chloride transporter), member 6 |
| SLC44A1 | solute carrier family 44 (choline transporter), member 1 |
| SP1 | Sp1 transcription factor |
| SPTBN2 | spectrin, beta, non-erythrocytic 2 |
| STAG3L1 | stromal antigen 3-like 1 (pseudogene) |
| STIM1 | stromal interaction molecule 1 |
| SUZ12P1 | suppressor of zeste 12 homolog pseudogene 1 |
| SYBU | syntabulin (syntaxin-interacting) |
| TAB1 | TGF-beta activated kinase 1/MAP3K7 binding protein 1 |
| TBC1D2 | TBC1 domain family, member 2 |
| TET3 | tet methylcytosine dioxygenase 3 |
| THRB | thyroid hormone receptor, beta |
| TMEM121 | transmembrane protein 121 |
| TNRC6B | trinucleotide repeat containing 6B |
| UNC119 | unc-119 homolog (C. elegans) |
| USP27X | ubiquitin specific peptidase 27, X-linked |
| VASH2 | vasohibin 2 |
| VPS9D1 | VPS9 domain containing 1 |
| XDH | xanthine dehydrogenase |
| XRCC3 | X-ray repair complementing defective repair in Chinese hamster cells 3 |
| ZC3H12A | zinc finger CCCH-type containing 12A |
| ZNF10 | zinc finger protein 10 |
| ZNF350 | zinc finger protein 350 |
| ZNF492 | zinc finger protein 492 |