| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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199 genes differentially expressed following the theophylline-4228 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABCC9 | ATP-binding cassette, sub-family C (CFTR/MRP), member 9 |
| ACSM3 | acyl-CoA synthetase medium-chain family member 3 |
| ACTN2 | actinin, alpha 2 |
| ADGRA2 | adhesion G protein-coupled receptor A2 |
| ADH7 | alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide |
| AIMP2 | aminoacyl tRNA synthetase complex-interacting multifunctional protein 2 |
| ALOX5 | arachidonate 5-lipoxygenase |
| APAF1 | apoptotic peptidase activating factor 1 |
| ARTN | artemin |
| ASPN | asporin |
| ATXN7L1 | ataxin 7-like 1 |
| BAZ2A | bromodomain adjacent to zinc finger domain, 2A |
| BCL2 | B-cell CLL/lymphoma 2 |
| BTBD18 | BTB (POZ) domain containing 18 |
| CCDC177 | coiled-coil domain containing 177 |
| CEACAM21 | carcinoembryonic antigen-related cell adhesion molecule 21 |
| CELF2 | CUGBP, Elav-like family member 2 |
| CEMIP | cell migration inducing protein, hyaluronan binding |
| CHODL | chondrolectin |
| CLUHP3 | clustered mitochondria (cluA/CLU1) homolog pseudogene 3 |
| CNTFR | ciliary neurotrophic factor receptor |
| COL4A6 | collagen, type IV, alpha 6 |
| CSF1 | colony stimulating factor 1 (macrophage) |
| DAPK2 | death-associated protein kinase 2 |
| DCTN2 | dynactin 2 (p50) |
| DTNA | dystrobrevin, alpha |
| FLT1 | fms-related tyrosine kinase 1 |
| FOXN3 | forkhead box N3 |
| GAL3ST4 | galactose-3-O-sulfotransferase 4 |
| GIMAP5 | GTPase, IMAP family member 5 |
| GK3P | glycerol kinase 3 pseudogene |
| GNA15 | guanine nucleotide binding protein (G protein), alpha 15 (Gq class) |
| GPATCH4 | G patch domain containing 4 |
| GPM6B | glycoprotein M6B |
| GPR21 | G protein-coupled receptor 21 |
| GPSM3 | G-protein signaling modulator 3 |
| HIC2 | hypermethylated in cancer 2 |
| HOXA1 | homeobox A1 |
| IGFBP7 | insulin-like growth factor binding protein 7 |
| IL1RN | interleukin 1 receptor antagonist |
| IL22RA1 | interleukin 22 receptor, alpha 1 |
| ITGA4 | integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor) |
| KCNJ15 | potassium channel, inwardly rectifying subfamily J, member 15 |
| KIAA1024 | KIAA1024 |
| LIMCH1 | LIM and calponin homology domains 1 |
| MAP1B | microtubule-associated protein 1B |
| MAPK11 | mitogen-activated protein kinase 11 |
| MARK1 | MAP/microtubule affinity-regulating kinase 1 |
| MCM3AP | minichromosome maintenance complex component 3 associated protein |
| MEFV | Mediterranean fever |
| MFAP3L | microfibrillar-associated protein 3-like |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 |
| MLX | MLX, MAX dimerization protein |
| MMP24 | matrix metallopeptidase 24 (membrane-inserted) |
| MST1 | macrophage stimulating 1 |
| MVB12B | multivesicular body subunit 12B |
| NOS1 | nitric oxide synthase 1 (neuronal) |
| NPHS2 | nephrosis 2, idiopathic, steroid-resistant (podocin) |
| NUP54 | nucleoporin 54kDa |
| PAOX | polyamine oxidase (exo-N4-amino) |
| PAPOLG | poly(A) polymerase gamma |
| PDCD2 | programmed cell death 2 |
| PDE4D | phosphodiesterase 4D, cAMP-specific |
| PKP4 | plakophilin 4 |
| PLEKHF1 | pleckstrin homology domain containing, family F (with FYVE domain) member 1 |
| PMS2P3 | postmeiotic segregation increased 2 pseudogene 3 |
| POFUT1 | protein O-fucosyltransferase 1 |
| PQLC2 | PQ loop repeat containing 2 |
| PRODH2 | proline dehydrogenase (oxidase) 2 |
| PTPN21 | protein tyrosine phosphatase, non-receptor type 21 |
| RIN3 | Ras and Rab interactor 3 |
| RUNX1 | runt-related transcription factor 1 |
| SARM1 | sterile alpha and TIR motif containing 1 |
| SLC10A1 | solute carrier family 10 (sodium/bile acid cotransporter), member 1 |
| SLC2A11 | solute carrier family 2 (facilitated glucose transporter), member 11 |
| SMAD4 | SMAD family member 4 |
| SP100 | SP100 nuclear antigen |
| SPOCK3 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3 |
| ST7L | suppression of tumorigenicity 7 like |
| SUGP1 | SURP and G patch domain containing 1 |
| SWAP70 | SWAP switching B-cell complex 70kDa subunit |
| TCF7 | transcription factor 7 (T-cell specific, HMG-box) |
| TESK1 | testis-specific kinase 1 |
| THBD | thrombomodulin |
| THOC5 | THO complex 5 |
| TLE2 | transducin-like enhancer of split 2 |
| TMOD1 | tropomodulin 1 |
| TNFAIP6 | tumor necrosis factor, alpha-induced protein 6 |
| TNXB | tenascin XB |
| TRPC1 | transient receptor potential cation channel, subfamily C, member 1 |
| TUBA3C | tubulin, alpha 3c |
| USP22 | ubiquitin specific peptidase 22 |
| VNN2 | vanin 2 |
| VWA5A | von Willebrand factor A domain containing 5A |
| WDR55 | WD repeat domain 55 |
| ZC2HC1C | zinc finger, C2HC-type containing 1C |
| ZNF219 | zinc finger protein 219 |
| ZNF225 | zinc finger protein 225 |
| ZNF230 | zinc finger protein 230 |
| ZNF287 | zinc finger protein 287 |
| Symbol | Name |
|---|---|
| ABCC2 | ATP-binding cassette, sub-family C (CFTR/MRP), member 2 |
| ACE | angiotensin I converting enzyme |
| ADAM23 | ADAM metallopeptidase domain 23 |
| ADGRB2 | adhesion G protein-coupled receptor B2 |
| ADGRE2 | adhesion G protein-coupled receptor E2 |
| C22ORF46 | chromosome 22 open reading frame 46 |
| CAMKMT | calmodulin-lysine N-methyltransferase |
| CASP5 | caspase 5, apoptosis-related cysteine peptidase |
| CCL2 | chemokine (C-C motif) ligand 2 |
| CLCA1 | chloride channel accessory 1 |
| CNGB3 | cyclic nucleotide gated channel beta 3 |
| COMP | cartilage oligomeric matrix protein |
| CPNE7 | copine VII |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 |
| CUZD1 | CUB and zona pellucida-like domains 1 |
| CXORF21 | chromosome X open reading frame 21 |
| DGCR9 | DiGeorge syndrome critical region gene 9 (non-protein coding) |
| DOK5 | docking protein 5 |
| ELP6 | elongator acetyltransferase complex subunit 6 |
| EYA3 | EYA transcriptional coactivator and phosphatase 3 |
| FAM86C1 | family with sequence similarity 86, member C1 |
| FGF23 | fibroblast growth factor 23 |
| FKBP5 | FK506 binding protein 5 |
| FRMPD1 | FERM and PDZ domain containing 1 |
| GABRP | gamma-aminobutyric acid (GABA) A receptor, pi |
| GABRR2 | gamma-aminobutyric acid (GABA) A receptor, rho 2 |
| GIF | gastric intrinsic factor (vitamin B synthesis) |
| GPR3 | G protein-coupled receptor 3 |
| GPR75 | G protein-coupled receptor 75 |
| GRM4 | glutamate receptor, metabotropic 4 |
| GTF2A1 | general transcription factor IIA, 1, 19/37kDa |
| HAMP | hepcidin antimicrobial peptide |
| HESX1 | HESX homeobox 1 |
| HIST1H1D | histone cluster 1, H1d |
| HIST1H2BO | histone cluster 1, H2bo |
| HIST1H4D | histone cluster 1, H4d |
| HOXC10 | homeobox C10 |
| HPR | haptoglobin-related protein |
| HSPA1L | heat shock 70kDa protein 1-like |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 |
| IFNA17 | interferon, alpha 17 |
| IL36RN | interleukin 36 receptor antagonist |
| IQSEC2 | IQ motif and Sec7 domain 2 |
| JUNB | jun B proto-oncogene |
| KCNN1 | potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 1 |
| KDM5C | lysine (K)-specific demethylase 5C |
| KDM8 | lysine (K)-specific demethylase 8 |
| KIAA1456 | KIAA1456 |
| KRT31 | keratin 31, type I |
| LAX1 | lymphocyte transmembrane adaptor 1 |
| LIME1 | Lck interacting transmembrane adaptor 1 |
| LLPH | LLP homolog, long-term synaptic facilitation (Aplysia) |
| LMO2 | LIM domain only 2 (rhombotin-like 1) |
| LPAR4 | lysophosphatidic acid receptor 4 |
| MTA2 | metastasis associated 1 family, member 2 |
| MTMR11 | myotubularin related protein 11 |
| MTSS1L | metastasis suppressor 1-like |
| MYO15A | myosin XVA |
| OLFML2A | olfactomedin-like 2A |
| OSBP2 | oxysterol binding protein 2 |
| PAIP2B | poly(A) binding protein interacting protein 2B |
| PDE12 | phosphodiesterase 12 |
| PHEX | phosphate regulating endopeptidase homolog, X-linked |
| PLEKHO1 | pleckstrin homology domain containing, family O member 1 |
| PRKG2 | protein kinase, cGMP-dependent, type II |
| PRM2 | protamine 2 |
| PRR15L | proline rich 15-like |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) |
| PTK6 | protein tyrosine kinase 6 |
| QPCTL | glutaminyl-peptide cyclotransferase-like |
| RAPGEFL1 | Rap guanine nucleotide exchange factor (GEF)-like 1 |
| RAPSN | receptor-associated protein of the synapse |
| RELB | v-rel avian reticuloendotheliosis viral oncogene homolog B |
| RPA4 | replication protein A4, 30kDa |
| SCGB2A2 | secretoglobin, family 2A, member 2 |
| SCIN | scinderin |
| SCUBE3 | signal peptide, CUB domain, EGF-like 3 |
| SGK2 | serum/glucocorticoid regulated kinase 2 |
| SLC16A6 | solute carrier family 16, member 6 |
| SLC37A1 | solute carrier family 37 (glucose-6-phosphate transporter), member 1 |
| SLC5A2 | solute carrier family 5 (sodium/glucose cotransporter), member 2 |
| SLC9A2 | solute carrier family 9, subfamily A (NHE2, cation proton antiporter 2), member 2 |
| SOX12 | SRY (sex determining region Y)-box 12 |
| SPATA1 | spermatogenesis associated 1 |
| SSBP3 | single stranded DNA binding protein 3 |
| STEAP4 | STEAP family member 4 |
| SULT1B1 | sulfotransferase family, cytosolic, 1B, member 1 |
| SUV39H2 | suppressor of variegation 3-9 homolog 2 (Drosophila) |
| TESPA1 | thymocyte expressed, positive selection associated 1 |
| TEX15 | testis expressed 15 |
| TLN1 | talin 1 |
| TNFSF12 | tumor necrosis factor (ligand) superfamily, member 12 |
| TNS2 | tensin 2 |
| TRABD | TraB domain containing |
| VEGFB | vascular endothelial growth factor B |
| WNT1 | wingless-type MMTV integration site family, member 1 |
| ZNF222 | zinc finger protein 222 |
| ZNF415 | zinc finger protein 415 |
| ZNF480 | zinc finger protein 480 |
