theophylline-4812 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

199 genes differentially expressed following the theophylline-4812 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCB9 ATP-binding cassette, sub-family B (MDR/TAP), member 9
ADARB1 adenosine deaminase, RNA-specific, B1
AKAP11 A kinase (PRKA) anchor protein 11
ALMS1 Alstrom syndrome protein 1
APAF1 apoptotic peptidase activating factor 1
APC adenomatous polyposis coli
AQP3 aquaporin 3 (Gill blood group)
ARHGEF11 Rho guanine nucleotide exchange factor (GEF) 11
ATP2A3 ATPase, Ca++ transporting, ubiquitous
AURKA aurora kinase A
BCAM basal cell adhesion molecule (Lutheran blood group)
BET1L Bet1 golgi vesicular membrane trafficking protein-like
BMP1 bone morphogenetic protein 1
C5AR2 complement component 5a receptor 2
C8A complement component 8, alpha polypeptide
CACNB2 calcium channel, voltage-dependent, beta 2 subunit
CACTIN cactin, spliceosome C complex subunit
CD22 CD22 molecule
CEND1 cell cycle exit and neuronal differentiation 1
COL13A1 collagen, type XIII, alpha 1
COMMD4 COMM domain containing 4
CYLD cylindromatosis (turban tumor syndrome)
CYTH4 cytohesin 4
DCTN1 dynactin 1
DMWD dystrophia myotonica, WD repeat containing
ENTPD4 ectonucleoside triphosphate diphosphohydrolase 4
ESR1 estrogen receptor 1
FCMR Fc fragment of IgM receptor
FGB fibrinogen beta chain
FKRP fukutin related protein
FLJ22184
FLJ42627 uncharacterized LOC645644
GAD1 glutamate decarboxylase 1 (brain, 67kDa)
GJB3 gap junction protein, beta 3, 31kDa
GLS2 glutaminase 2 (liver, mitochondrial)
GZMK granzyme K (granzyme 3; tryptase II)
HIST1H1E histone cluster 1, H1e
HIST1H4F histone cluster 1, H4f
HYAL3 hyaluronoglucosaminidase 3
IFFO1 intermediate filament family orphan 1
IKBKE inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
IKZF1 IKAROS family zinc finger 1 (Ikaros)
KANSL3 KAT8 regulatory NSL complex subunit 3
KHSRP KH-type splicing regulatory protein
KRIT1 KRIT1, ankyrin repeat containing
LIF leukemia inhibitory factor
LTB4R leukotriene B4 receptor
MAP4K2 mitogen-activated protein kinase kinase kinase kinase 2
MED18 mediator complex subunit 18
MPPE1 metallophosphoesterase 1
MST1 macrophage stimulating 1
NAT6 N-acetyltransferase 6 (GCN5-related)
NCOR2 nuclear receptor corepressor 2
NFX1 nuclear transcription factor, X-box binding 1
OSBPL10 oxysterol binding protein-like 10
PCBP3 poly(rC) binding protein 3
PHC3 polyhomeotic homolog 3 (Drosophila)
PICK1 protein interacting with PRKCA 1
PLEKHF1 pleckstrin homology domain containing, family F (with FYVE domain) member 1
PLK3 polo-like kinase 3
PODNL1 podocan-like 1
PPP1R15A protein phosphatase 1, regulatory subunit 15A
PRKAR1B protein kinase, cAMP-dependent, regulatory, type I, beta
PTRF polymerase I and transcript release factor
RAB11FIP5 RAB11 family interacting protein 5 (class I)
RABGAP1 RAB GTPase activating protein 1
RBM19 RNA binding motif protein 19
RCAN1 regulator of calcineurin 1
RRN3P1 RNA polymerase I transcription factor homolog (S. cerevisiae) pseudogene 1
RUNX3 runt-related transcription factor 3
SAFB2 scaffold attachment factor B2
SC5D sterol-C5-desaturase
SIRPB1 signal-regulatory protein beta 1
SIRT5 sirtuin 5
SKIL SKI-like proto-oncogene
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SOAT2 sterol O-acyltransferase 2
SOGA1 suppressor of glucose, autophagy associated 1
SPON1 spondin 1, extracellular matrix protein
STK11 serine/threonine kinase 11
STS steroid sulfatase (microsomal), isozyme S
TBL1Y transducin (beta)-like 1, Y-linked
TJAP1 tight junction associated protein 1 (peripheral)
TMC6 transmembrane channel-like 6
TMEM63A transmembrane protein 63A
TNFRSF11B tumor necrosis factor receptor superfamily, member 11b
TNFRSF8 tumor necrosis factor receptor superfamily, member 8
TNS1 tensin 1
TRIO trio Rho guanine nucleotide exchange factor
UBOX5 U-box domain containing 5
UBXN1 UBX domain protein 1
UTRN utrophin
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor
WDR62 WD repeat domain 62
WNK1 WNK lysine deficient protein kinase 1
XPNPEP3 X-prolyl aminopeptidase 3, mitochondrial
XRCC2 X-ray repair complementing defective repair in Chinese hamster cells 2
XRCC3 X-ray repair complementing defective repair in Chinese hamster cells 3
ZIC3 Zic family member 3
ZNF551 zinc finger protein 551

decreased expression

Symbol Name
ACTR8 ARP8 actin-related protein 8 homolog (yeast)
AIDA axin interactor, dorsalization associated
AKTIP AKT interacting protein
ARHGEF26 Rho guanine nucleotide exchange factor (GEF) 26
ARID3B AT rich interactive domain 3B (BRIGHT-like)
ASAP1 ArfGAP with SH3 domain, ankyrin repeat and PH domain 1
ASPHD1 aspartate beta-hydroxylase domain containing 1
ATAD5 ATPase family, AAA domain containing 5
ATAT1 alpha tubulin acetyltransferase 1
B3GNT3 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3
BRIP1 BRCA1 interacting protein C-terminal helicase 1
BRPF1 bromodomain and PHD finger containing, 1
C1QTNF9B-AS1 C1QTNF9B antisense RNA 1
CD302 CD302 molecule
CEP97 centrosomal protein 97kDa
CLSPN claspin
COPZ2 coatomer protein complex, subunit zeta 2
CRIP1 cysteine-rich protein 1 (intestinal)
CYB5R4 cytochrome b5 reductase 4
DCLRE1A DNA cross-link repair 1A
DCTN4 dynactin 4 (p62)
DENND4A DENN/MADD domain containing 4A
DHX35 DEAH (Asp-Glu-Ala-His) box polypeptide 35
EIF5A2 eukaryotic translation initiation factor 5A2
EXOC2 exocyst complex component 2
FADS2 fatty acid desaturase 2
FAM188A family with sequence similarity 188, member A
FLJ21369 uncharacterized protein FLJ21369
FZD3 frizzled class receptor 3
GJA1 gap junction protein, alpha 1, 43kDa
GMPR guanosine monophosphate reductase
GNA13 guanine nucleotide binding protein (G protein), alpha 13
GPX2 glutathione peroxidase 2
HIST1H4D histone cluster 1, H4d
HIVEP3 human immunodeficiency virus type I enhancer binding protein 3
HMOX1 heme oxygenase 1
HPSE heparanase
HSPA2 heat shock 70kDa protein 2
KDM3A lysine (K)-specific demethylase 3A
KIAA0895 KIAA0895
KIF16B kinesin family member 16B
KLHL28 kelch-like family member 28
LAMA3 laminin, alpha 3
LINC00115 long intergenic non-protein coding RNA 115
LOC730101 uncharacterized LOC730101
MBIP MAP3K12 binding inhibitory protein 1
MEFV Mediterranean fever
METTL16 methyltransferase like 16
MGAT4A mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme A
NCAM2 neural cell adhesion molecule 2
NIPAL2 NIPA-like domain containing 2
NT5DC3 5'-nucleotidase domain containing 3
OVGP1 oviductal glycoprotein 1, 120kDa
PACS1 phosphofurin acidic cluster sorting protein 1
PDHX pyruvate dehydrogenase complex, component X
PGPEP1 pyroglutamyl-peptidase I
PIM2 Pim-2 proto-oncogene, serine/threonine kinase
PRSS16 protease, serine, 16 (thymus)
PRSS53 protease, serine, 53
PSTPIP2 proline-serine-threonine phosphatase interacting protein 2
PYCRL pyrroline-5-carboxylate reductase-like
RAB3IL1 RAB3A interacting protein (rabin3)-like 1
RNF146 ring finger protein 146
RUNDC3B RUN domain containing 3B
SAYSD1 SAYSVFN motif domain containing 1
SCGB2A2 secretoglobin, family 2A, member 2
SCN1B sodium channel, voltage gated, type I beta subunit
SGCG sarcoglycan, gamma (35kDa dystrophin-associated glycoprotein)
SKA1 spindle and kinetochore associated complex subunit 1
SLC22A5 solute carrier family 22 (organic cation/carnitine transporter), member 5
SLC25A23 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23
SLC25A40 solute carrier family 25, member 40
STRA6 stimulated by retinoic acid 6
TAF1A TATA box binding protein (TBP)-associated factor, RNA polymerase I, A, 48kDa
TBC1D19 TBC1 domain family, member 19
TBL1XR1 transducin (beta)-like 1 X-linked receptor 1
TCHH trichohyalin
TIMM22 translocase of inner mitochondrial membrane 22 homolog (yeast)
TMEM2 transmembrane protein 2
TRMT13 tRNA methyltransferase 13 homolog (S. cerevisiae)
TRPV1 transient receptor potential cation channel, subfamily V, member 1
TSPAN5 tetraspanin 5
TTC30A tetratricopeptide repeat domain 30A
TTC9 tetratricopeptide repeat domain 9
TTLL1 tubulin tyrosine ligase-like family member 1
UBE2W ubiquitin-conjugating enzyme E2W (putative)
UPK2 uroplakin 2
USP18 ubiquitin specific peptidase 18
USP6NL USP6 N-terminal like
VPS33A vacuolar protein sorting 33 homolog A (S. cerevisiae)
WDR44 WD repeat domain 44
ZFP69B ZFP69 zinc finger protein B
ZNF107 zinc finger protein 107
ZNF180 zinc finger protein 180
ZNF205 zinc finger protein 205
ZNF32 zinc finger protein 32
ZNF552 zinc finger protein 552
ZNF573 zinc finger protein 573
ZNF770 zinc finger protein 770