therapeutics Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
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Genes

120 genes co-occuring with the biological term therapeutics in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
AKT1 v-akt murine thymoma viral oncogene homolog 1
ALCAM activated leukocyte cell adhesion molecule
ALK anaplastic lymphoma receptor tyrosine kinase
ANXA2 annexin A2
APP amyloid beta (A4) precursor protein
AR androgen receptor
ASAP1 ArfGAP with SH3 domain, ankyrin repeat and PH domain 1
ATG12 autophagy related 12
BCL2 B-cell CLL/lymphoma 2
BCL2L1 BCL2-like 1
BRAF B-Raf proto-oncogene, serine/threonine kinase
BRCA1 breast cancer 1, early onset
BRCA2 breast cancer 2, early onset
BSG basigin (Ok blood group)
CA9 carbonic anhydrase IX
CACNA1G calcium channel, voltage-dependent, T type, alpha 1G subunit
CASP2 caspase 2, apoptosis-related cysteine peptidase
CASP8 caspase 8, apoptosis-related cysteine peptidase
CBFB core-binding factor, beta subunit
CCND1 cyclin D1
CCR5 chemokine (C-C motif) receptor 5 (gene/pseudogene)
CD109 CD109 molecule
CD4 CD4 molecule
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)
CHUK conserved helix-loop-helix ubiquitous kinase
CNR1 cannabinoid receptor 1 (brain)
CNR2 cannabinoid receptor 2 (macrophage)
CTNND1 catenin (cadherin-associated protein), delta 1
CTTN cortactin
CXCL12 chemokine (C-X-C motif) ligand 12
CXCL8 chemokine (C-X-C motif) ligand 8
CXCR2 chemokine (C-X-C motif) receptor 2
CXCR4 chemokine (C-X-C motif) receptor 4
CYLD cylindromatosis (turban tumor syndrome)
DMPK dystrophia myotonica-protein kinase
EFNB2 ephrin-B2
EGFR epidermal growth factor receptor
EHF ets homologous factor
EIF2AK2 eukaryotic translation initiation factor 2-alpha kinase 2
EIF4E eukaryotic translation initiation factor 4E
EPHB4 EPH receptor B4
ERBB2 erb-b2 receptor tyrosine kinase 2
ERBB2IP erbb2 interacting protein
ESR1 estrogen receptor 1
ESR2 estrogen receptor 2 (ER beta)
F2R coagulation factor II (thrombin) receptor
FASN fatty acid synthase
FDPS farnesyl diphosphate synthase
FFAR4 free fatty acid receptor 4
FGFR2 fibroblast growth factor receptor 2
FGFR3 fibroblast growth factor receptor 3
FOXO3 forkhead box O3
GPER1 G protein-coupled estrogen receptor 1
GPNMB glycoprotein (transmembrane) nmb
GRB7 growth factor receptor-bound protein 7
HGF hepatocyte growth factor (hepapoietin A; scatter factor)
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
HMGB1 high mobility group box 1
HMOX1 heme oxygenase 1
HSF1 heat shock transcription factor 1
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1
HSPB6 heat shock protein, alpha-crystallin-related, B6
HTR1A 5-hydroxytryptamine (serotonin) receptor 1A, G protein-coupled
HTT huntingtin
IGF1 insulin-like growth factor 1 (somatomedin C)
IGF1R insulin-like growth factor 1 receptor
IL17A interleukin 17A
IL1B interleukin 1, beta
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)
ITGA5 integrin, alpha 5 (fibronectin receptor, alpha polypeptide)
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)
ITGB7 integrin, beta 7
KDR kinase insert domain receptor
L1CAM L1 cell adhesion molecule
LATS2 large tumor suppressor kinase 2
LOXL2 lysyl oxidase-like 2
LRRK2 leucine-rich repeat kinase 2
MC4R melanocortin 4 receptor
MET MET proto-oncogene, receptor tyrosine kinase
MIR124-1 microRNA 124-1
MIR133A1 microRNA 133a-1
MIR21 microRNA 21
MIR99A microRNA 99a
MMP1 matrix metallopeptidase 1
MTF1 metal-regulatory transcription factor 1
MTOR mechanistic target of rapamycin (serine/threonine kinase)
MYC v-myc avian myelocytomatosis viral oncogene homolog
MYH11 myosin, heavy chain 11, smooth muscle
NCAM1 neural cell adhesion molecule 1
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
NGF nerve growth factor (beta polypeptide)
NGFR nerve growth factor receptor
NME1 NME/NM23 nucleoside diphosphate kinase 1
PAH phenylalanine hydroxylase
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
PLAUR plasminogen activator, urokinase receptor
POLK polymerase (DNA directed) kappa
PRKCE protein kinase C, epsilon
PRMT7 protein arginine methyltransferase 7
PRNP prion protein
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
RAP1GDS1 RAP1, GTP-GDP dissociation stimulator 1
SIRT1 sirtuin 1
SOST sclerostin
SP1 Sp1 transcription factor
SREBF1 sterol regulatory element binding transcription factor 1
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
THRAP3 thyroid hormone receptor associated protein 3
TIMP1 TIMP metallopeptidase inhibitor 1
TNFRSF12A tumor necrosis factor receptor superfamily, member 12A
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TSC22D3 TSC22 domain family, member 3
TSG101 tumor susceptibility 101
TWIST1 twist family bHLH transcription factor 1
UBE2Q2 ubiquitin-conjugating enzyme E2Q family member 2
VEGFA vascular endothelial growth factor A
VPRBP Vpr (HIV-1) binding protein
XRCC6 X-ray repair complementing defective repair in Chinese hamster cells 6
YBX1 Y box binding protein 1
ZBTB33 zinc finger and BTB domain containing 33