thiamazole-2570 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the thiamazole-2570 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACRV1 acrosomal vesicle protein 1
ADORA3 adenosine A3 receptor
ALDH1B1 aldehyde dehydrogenase 1 family, member B1
APBB2 amyloid beta (A4) precursor protein-binding, family B, member 2
ARHGEF9 Cdc42 guanine nucleotide exchange factor (GEF) 9
ARL2BP ADP-ribosylation factor-like 2 binding protein
ASB1 ankyrin repeat and SOCS box containing 1
ATP6V0A1 ATPase, H+ transporting, lysosomal V0 subunit a1
ATP7A ATPase, Cu++ transporting, alpha polypeptide
BACH1 BTB and CNC homology 1, basic leucine zipper transcription factor 1
BTG2 BTG family, member 2
CCDC71 coiled-coil domain containing 71
CCL20 chemokine (C-C motif) ligand 20
CD52 CD52 molecule
CD59 CD59 molecule, complement regulatory protein
CD84 CD84 molecule
CECR1 cat eye syndrome chromosome region, candidate 1
CELSR2 cadherin, EGF LAG seven-pass G-type receptor 2
CEP250 centrosomal protein 250kDa
CLCA1 chloride channel accessory 1
COBLL1 cordon-bleu WH2 repeat protein-like 1
COL6A1 collagen, type VI, alpha 1
CRY2 cryptochrome circadian clock 2
CSF2RA colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage)
DAPK2 death-associated protein kinase 2
DKK2 dickkopf WNT signaling pathway inhibitor 2
DNAJB12 DnaJ (Hsp40) homolog, subfamily B, member 12
DUSP4 dual specificity phosphatase 4
DYNC2H1 dynein, cytoplasmic 2, heavy chain 1
E2F1 E2F transcription factor 1
EMILIN2 elastin microfibril interfacer 2
FAM127B family with sequence similarity 127, member B
FCAR Fc fragment of IgA receptor
FCGR1A Fc fragment of IgG, high affinity Ia, receptor (CD64)
FEZ2 fasciculation and elongation protein zeta 2 (zygin II)
FGL1 fibrinogen-like 1
FST follistatin
G3BP1 GTPase activating protein (SH3 domain) binding protein 1
GHRHR growth hormone releasing hormone receptor
GRIP2 glutamate receptor interacting protein 2
HCAR3 hydroxycarboxylic acid receptor 3
HNF1B HNF1 homeobox B
HYAL1 hyaluronoglucosaminidase 1
ICOSLG inducible T-cell co-stimulator ligand
IRF5 interferon regulatory factor 5
IZUMO4 IZUMO family member 4
KCNN1 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 1
KDM8 lysine (K)-specific demethylase 8
KIAA1107 KIAA1107
KLF12 Kruppel-like factor 12
KLHL20 kelch-like family member 20
L3MBTL1 l(3)mbt-like 1 (Drosophila)
LARP7 La ribonucleoprotein domain family, member 7
LILRB2 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 2
LSS lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase)
LZTS3 leucine zipper, putative tumor suppressor family member 3
MICAL3 microtubule associated monooxygenase, calponin and LIM domain containing 3
MLX MLX, MAX dimerization protein
MTA2 metastasis associated 1 family, member 2
NBR2 neighbor of BRCA1 gene 2 (non-protein coding)
NDRG2 NDRG family member 2
NFKBIB nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
NPC1 Niemann-Pick disease, type C1
NPEPL1 aminopeptidase-like 1
NR2F2 nuclear receptor subfamily 2, group F, member 2
OR1D2 olfactory receptor, family 1, subfamily D, member 2
OXTR oxytocin receptor
PDE4D phosphodiesterase 4D, cAMP-specific
PER1 period circadian clock 1
PLA2G15 phospholipase A2, group XV
PLCH1 phospholipase C, eta 1
PLSCR3 phospholipid scramblase 3
PSD3 pleckstrin and Sec7 domain containing 3
RAP1GAP2 RAP1 GTPase activating protein 2
RHOH ras homolog family member H
RND1 Rho family GTPase 1
RPL13 ribosomal protein L13
RRP1B ribosomal RNA processing 1B
SHB Src homology 2 domain containing adaptor protein B
SHMT1 serine hydroxymethyltransferase 1 (soluble)
SIGLEC7 sialic acid binding Ig-like lectin 7
SKP2 S-phase kinase-associated protein 2, E3 ubiquitin protein ligase
SLC23A2 solute carrier family 23 (ascorbic acid transporter), member 2
SLC35D2 solute carrier family 35 (UDP-GlcNAc/UDP-glucose transporter), member D2
SMAD3 SMAD family member 3
ST7L suppression of tumorigenicity 7 like
TLN2 talin 2
TMEM63A transmembrane protein 63A
TNFRSF12A tumor necrosis factor receptor superfamily, member 12A
TRIM36 tripartite motif containing 36
UBE2I ubiquitin-conjugating enzyme E2I
UBR4 ubiquitin protein ligase E3 component n-recognin 4
USP2 ubiquitin specific peptidase 2
USP22 ubiquitin specific peptidase 22
WDR55 WD repeat domain 55
ZBTB20 zinc finger and BTB domain containing 20
ZFYVE9 zinc finger, FYVE domain containing 9
ZNF215 zinc finger protein 215
ZNF821 zinc finger protein 821

decreased expression

Symbol Name
ABCC2 ATP-binding cassette, sub-family C (CFTR/MRP), member 2
ADGRD2 adhesion G protein-coupled receptor D2
ADGRE3 adhesion G protein-coupled receptor E3
ATP13A2 ATPase type 13A2
BMP15 bone morphogenetic protein 15
BRAF B-Raf proto-oncogene, serine/threonine kinase
C16ORF59 chromosome 16 open reading frame 59
C5AR1 complement component 5a receptor 1
C7ORF43 chromosome 7 open reading frame 43
CCDC85C coiled-coil domain containing 85C
CCL21 chemokine (C-C motif) ligand 21
CFAP45 cilia and flagella associated protein 45
CHST8 carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 8
CNKSR2 connector enhancer of kinase suppressor of Ras 2
CRYGC crystallin, gamma C
CYP7B1 cytochrome P450, family 7, subfamily B, polypeptide 1
DGCR11 DiGeorge syndrome critical region gene 11 (non-protein coding)
DKFZP434L187 uncharacterized LOC26082
DMTN dematin actin binding protein
DSPP dentin sialophosphoprotein
ELSPBP1 epididymal sperm binding protein 1
EPN1 epsin 1
EXD3 exonuclease 3'-5' domain containing 3
EXOSC1 exosome component 1
EYA3 EYA transcriptional coactivator and phosphatase 3
FAM120C family with sequence similarity 120C
FAM163A family with sequence similarity 163, member A
FAM50B family with sequence similarity 50, member B
FBXO40 F-box protein 40
FMO4 flavin containing monooxygenase 4
GPR68 G protein-coupled receptor 68
GSN-AS1 GSN antisense RNA 1
GSTT1 glutathione S-transferase theta 1
HIST1H2AI histone cluster 1, H2ai
HIST1H3G histone cluster 1, H3g
HIST1H3I histone cluster 1, H3i
HIVEP3 human immunodeficiency virus type I enhancer binding protein 3
HOXB9 homeobox B9
HOXC8 homeobox C8
HRH2 histamine receptor H2
IFIT2 interferon-induced protein with tetratricopeptide repeats 2
IGKV3-20 immunoglobulin kappa variable 3-20
IGLL3P immunoglobulin lambda-like polypeptide 3, pseudogene
IL12RB1 interleukin 12 receptor, beta 1
IRF2BP1 interferon regulatory factor 2 binding protein 1
JAM3 junctional adhesion molecule 3
KLHL36 kelch-like family member 36
LIME1 Lck interacting transmembrane adaptor 1
LOC257152 uncharacterized LOC257152
LOC729164 hCG1732469
LPPR1 lipid phosphate phosphatase-related protein type 1
LRRC6 leucine rich repeat containing 6
MAP3K1 mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase
MAP6D1 MAP6 domain containing 1
ME3 malic enzyme 3, NADP(+)-dependent, mitochondrial
MPZ myelin protein zero
MTHFSD methenyltetrahydrofolate synthetase domain containing
MTSS1L metastasis suppressor 1-like
MYOZ3 myozenin 3
NOD2 nucleotide-binding oligomerization domain containing 2
OCLN occludin
OVGP1 oviductal glycoprotein 1, 120kDa
PBOV1 prostate and breast cancer overexpressed 1
PCDH12 protocadherin 12
PDK4 pyruvate dehydrogenase kinase, isozyme 4
PKIG protein kinase (cAMP-dependent, catalytic) inhibitor gamma
PLAT plasminogen activator, tissue
PMEL premelanosome protein
PORCN porcupine homolog (Drosophila)
RAB13 RAB13, member RAS oncogene family
RAPGEFL1 Rap guanine nucleotide exchange factor (GEF)-like 1
RFNG RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
RFPL1S RFPL1 antisense RNA 1
RNF126P1 ring finger protein 126 pseudogene 1
SIGLEC9 sialic acid binding Ig-like lectin 9
SIK1 salt-inducible kinase 1
SLC12A8 solute carrier family 12, member 8
SLC25A22 solute carrier family 25 (mitochondrial carrier: glutamate), member 22
SLCO1B1 solute carrier organic anion transporter family, member 1B1
SMR3A submaxillary gland androgen regulated protein 3A
SPEF1 sperm flagellar 1
STMN4 stathmin-like 4
STX11 syntaxin 11
SULT1B1 sulfotransferase family, cytosolic, 1B, member 1
TAS2R1 taste receptor, type 2, member 1
TCTN2 tectonic family member 2
TIGD6 tigger transposable element derived 6
TLR4 toll-like receptor 4
TMEM209 transmembrane protein 209
TMEM212 transmembrane protein 212
TNNT1 troponin T type 1 (skeletal, slow)
TSC22D4 TSC22 domain family, member 4
UNC93B1 unc-93 homolog B1 (C. elegans)
UPK3A uroplakin 3A
USP5 ubiquitin specific peptidase 5 (isopeptidase T)
VWA1 von Willebrand factor A domain containing 1
WASF3 WAS protein family, member 3
XYLT2 xylosyltransferase II
ZNF280A zinc finger protein 280A