thiamazole-3432 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

192 genes differentially expressed following the thiamazole-3432 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AGMAT agmatine ureohydrolase (agmatinase)
APBA2 amyloid beta (A4) precursor protein-binding, family A, member 2
APOM apolipoprotein M
ARHGAP1 Rho GTPase activating protein 1
ARVCF armadillo repeat gene deleted in velocardiofacial syndrome
ATP6V0A1 ATPase, H+ transporting, lysosomal V0 subunit a1
BLVRA biliverdin reductase A
BST2 bone marrow stromal cell antigen 2
C1ORF159 chromosome 1 open reading frame 159
C4ORF29 chromosome 4 open reading frame 29
CA4 carbonic anhydrase IV
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase
CDH8 cadherin 8, type 2
COL7A1 collagen, type VII, alpha 1
CST4 cystatin S
CTBP2 C-terminal binding protein 2
CXADR coxsackie virus and adenovirus receptor
CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4
DIAPH1 diaphanous-related formin 1
DICER1 dicer 1, ribonuclease type III
DIS3 DIS3 exosome endoribonuclease and 3'-5' exoribonuclease
DPY19L2P2 DPY19L2 pseudogene 2
DZIP3 DAZ interacting zinc finger protein 3
ENPEP glutamyl aminopeptidase (aminopeptidase A)
FAM120C family with sequence similarity 120C
FGFR1 fibroblast growth factor receptor 1
FKBP5 FK506 binding protein 5
FKBP8 FK506 binding protein 8, 38kDa
GAMT guanidinoacetate N-methyltransferase
GCNT2 glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group)
GFI1 growth factor independent 1 transcription repressor
GK glycerol kinase
GLYR1 glyoxylate reductase 1 homolog (Arabidopsis)
GNG7 guanine nucleotide binding protein (G protein), gamma 7
GPATCH3 G patch domain containing 3
HFE hemochromatosis
HIPK3 homeodomain interacting protein kinase 3
HLA-DMA major histocompatibility complex, class II, DM alpha
INCENP inner centromere protein antigens 135/155kDa
ING2 inhibitor of growth family, member 2
IQCE IQ motif containing E
KAT8 K(lysine) acetyltransferase 8
KCNJ3 potassium channel, inwardly rectifying subfamily J, member 3
KHK ketohexokinase (fructokinase)
KLF3 Kruppel-like factor 3 (basic)
KLHL25 kelch-like family member 25
LARP6 La ribonucleoprotein domain family, member 6
LGALS4 lectin, galactoside-binding, soluble, 4
LRRC6 leucine rich repeat containing 6
MAN1A1 mannosidase, alpha, class 1A, member 1
MYL4 myosin, light chain 4, alkali; atrial, embryonic
NF1 neurofibromin 1
NFKBIB nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
NKX3-2 NK3 homeobox 2
NPC1 Niemann-Pick disease, type C1
NPHP1 nephronophthisis 1 (juvenile)
OR2F1 olfactory receptor, family 2, subfamily F, member 1 (gene/pseudogene)
PARVA parvin, alpha
PDE3B phosphodiesterase 3B, cGMP-inhibited
PDE8B phosphodiesterase 8B
PDLIM5 PDZ and LIM domain 5
PICK1 protein interacting with PRKCA 1
PLCB1 phospholipase C, beta 1 (phosphoinositide-specific)
PLCH1 phospholipase C, eta 1
PLXNB1 plexin B1
PMS2P3 postmeiotic segregation increased 2 pseudogene 3
PODNL1 podocan-like 1
PSMB2 proteasome (prosome, macropain) subunit, beta type, 2
PSMD11 proteasome (prosome, macropain) 26S subunit, non-ATPase, 11
PTBP1 polypyrimidine tract binding protein 1
PTGES prostaglandin E synthase
PTHLH parathyroid hormone-like hormone
PVR poliovirus receptor
RAB3D RAB3D, member RAS oncogene family
RABGAP1 RAB GTPase activating protein 1
RASAL2 RAS protein activator like 2
RCHY1 ring finger and CHY zinc finger domain containing 1, E3 ubiquitin protein ligase
RGS3 regulator of G-protein signaling 3
SCD5 stearoyl-CoA desaturase 5
SLC30A3 solute carrier family 30 (zinc transporter), member 3
SLC6A6 solute carrier family 6 (neurotransmitter transporter), member 6
SLC9A3R2 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 2
SNAPC3 small nuclear RNA activating complex, polypeptide 3, 50kDa
STARD3 StAR-related lipid transfer (START) domain containing 3
SUZ12P1 suppressor of zeste 12 homolog pseudogene 1
TESC tescalcin
TLE2 transducin-like enhancer of split 2
TMEM63A transmembrane protein 63A
TMPRSS4 transmembrane protease, serine 4
TREX1 three prime repair exonuclease 1
TRIM62 tripartite motif containing 62
WDTC1 WD and tetratricopeptide repeats 1
ZBTB48 zinc finger and BTB domain containing 48
ZMYND8 zinc finger, MYND-type containing 8
ZNF440 zinc finger protein 440
ZNF45 zinc finger protein 45

decreased expression

Symbol Name
ABLIM3 actin binding LIM protein family, member 3
ARHGEF10L Rho guanine nucleotide exchange factor (GEF) 10-like
ATP13A2 ATPase type 13A2
BATF basic leucine zipper transcription factor, ATF-like
CAPRIN2 caprin family member 2
CCNE1 cyclin E1
CDR2L cerebellar degeneration-related protein 2-like
CEP72 centrosomal protein 72kDa
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CIDEC cell death-inducing DFFA-like effector c
CISH cytokine inducible SH2-containing protein
CLEC16A C-type lectin domain family 16, member A
COLGALT1 collagen beta(1-O)galactosyltransferase 1
CRLF1 cytokine receptor-like factor 1
CRTAP cartilage associated protein
CUEDC1 CUE domain containing 1
DFFB DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase)
DTX2P1-UPK3BP1-PMS2P11 DTX2P1-UPK3BP1-PMS2P11 readthrough transcribed pseudogene
DUSP8 dual specificity phosphatase 8
EIF4EBP1 eukaryotic translation initiation factor 4E binding protein 1
EPB41L5 erythrocyte membrane protein band 4.1 like 5
EPS8L2 EPS8-like 2
F3 coagulation factor III (thromboplastin, tissue factor)
FAM155B family with sequence similarity 155, member B
FAM192A family with sequence similarity 192, member A
FBXO31 F-box protein 31
FBXW7 F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
FGF23 fibroblast growth factor 23
FKBP10 FK506 binding protein 10, 65 kDa
FUT1 fucosyltransferase 1 (galactoside 2-alpha-L-fucosyltransferase, H blood group)
FZD2 frizzled class receptor 2
GLS2 glutaminase 2 (liver, mitochondrial)
GUCY1B2 guanylate cyclase 1, soluble, beta 2 (pseudogene)
HERC6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
HIST1H1D histone cluster 1, H1d
HIST1H2BI histone cluster 1, H2bi
HIST1H4C histone cluster 1, H4c
HSD17B1 hydroxysteroid (17-beta) dehydrogenase 1
INPPL1 inositol polyphosphate phosphatase-like 1
JMJD4 jumonji domain containing 4
KCNMB3 potassium channel subfamily M regulatory beta subunit 3
KCTD7 potassium channel tetramerization domain containing 7
KIAA0125 KIAA0125
KIZ kizuna centrosomal protein
KLHL26 kelch-like family member 26
KREMEN2 kringle containing transmembrane protein 2
KRT13 keratin 13, type I
LOC257152 uncharacterized LOC257152
LRFN3 leucine rich repeat and fibronectin type III domain containing 3
LZTR1 leucine-zipper-like transcription regulator 1
MAP3K11 mitogen-activated protein kinase kinase kinase 11
MAP3K2 mitogen-activated protein kinase kinase kinase 2
MMP9 matrix metallopeptidase 9
NDRG4 NDRG family member 4
NPM3 nucleophosmin/nucleoplasmin 3
NT5DC3 5'-nucleotidase domain containing 3
ORAI3 ORAI calcium release-activated calcium modulator 3
PCDHB3 protocadherin beta 3
PDK1 pyruvate dehydrogenase kinase, isozyme 1
PLA2G15 phospholipase A2, group XV
PLD2 phospholipase D2
PMCH pro-melanin-concentrating hormone
PMEPA1 prostate transmembrane protein, androgen induced 1
PPT2 palmitoyl-protein thioesterase 2
PRPH peripherin
PRSS22 protease, serine, 22
RABL6 RAB, member RAS oncogene family-like 6
RAD9A RAD9 homolog A (S. pombe)
RNF121 ring finger protein 121
ROM1 retinal outer segment membrane protein 1
RPRD2 regulation of nuclear pre-mRNA domain containing 2
SCML1 sex comb on midleg-like 1 (Drosophila)
SLC17A5 solute carrier family 17 (acidic sugar transporter), member 5
SMEK2 SMEK homolog 2, suppressor of mek1 (Dictyostelium)
SNAPC2 small nuclear RNA activating complex, polypeptide 2, 45kDa
SNHG3 small nucleolar RNA host gene 3
SPATA2L spermatogenesis associated 2-like
SSBP3 single stranded DNA binding protein 3
TIMM17B translocase of inner mitochondrial membrane 17 homolog B (yeast)
TIMP2 TIMP metallopeptidase inhibitor 2
TMEM180 transmembrane protein 180
TNKS2 tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2
TRIP4 thyroid hormone receptor interactor 4
TRPV1 transient receptor potential cation channel, subfamily V, member 1
VPS33A vacuolar protein sorting 33 homolog A (S. cerevisiae)
WDR60 WD repeat domain 60
XYLT2 xylosyltransferase II
YIPF3 Yip1 domain family, member 3
ZBTB25 zinc finger and BTB domain containing 25
ZBTB39 zinc finger and BTB domain containing 39
ZCCHC6 zinc finger, CCHC domain containing 6
ZCWPW1 zinc finger, CW type with PWWP domain 1
ZFP69B ZFP69 zinc finger protein B
ZNF189 zinc finger protein 189
ZNF571 zinc finger protein 571
ZNF862 zinc finger protein 862