thiamazole-3815 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

194 genes differentially expressed following the thiamazole-3815 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACRV1 acrosomal vesicle protein 1
ADPRH ADP-ribosylarginine hydrolase
ANGPTL2 angiopoietin-like 2
ANO3 anoctamin 3
APAF1 apoptotic peptidase activating factor 1
AQP1 aquaporin 1 (Colton blood group)
ARHGEF17 Rho guanine nucleotide exchange factor (GEF) 17
ATF6B activating transcription factor 6 beta
C10ORF12 chromosome 10 open reading frame 12
C14ORF105 chromosome 14 open reading frame 105
C7ORF26 chromosome 7 open reading frame 26
CACNA1D calcium channel, voltage-dependent, L type, alpha 1D subunit
CD6 CD6 molecule
CDK18 cyclin-dependent kinase 18
CEACAM3 carcinoembryonic antigen-related cell adhesion molecule 3
CEL carboxyl ester lipase
CHAT choline O-acetyltransferase
CHST5 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 5
CNTD2 cyclin N-terminal domain containing 2
CRYAA crystallin, alpha A
CRYGC crystallin, gamma C
CXCL9 chemokine (C-X-C motif) ligand 9
DENND1C DENN/MADD domain containing 1C
DIAPH2-AS1 DIAPH2 antisense RNA 1
DPF1 D4, zinc and double PHD fingers family 1
EFR3B EFR3 homolog B (S. cerevisiae)
EHMT1 euchromatic histone-lysine N-methyltransferase 1
ETV1 ets variant 1
EYA2 EYA transcriptional coactivator and phosphatase 2
FAM214B family with sequence similarity 214, member B
FCGR2A Fc fragment of IgG, low affinity IIa, receptor (CD32)
FLVCR2 feline leukemia virus subgroup C cellular receptor family, member 2
G3BP1 GTPase activating protein (SH3 domain) binding protein 1
GIMAP6 GTPase, IMAP family member 6
GPD1 glycerol-3-phosphate dehydrogenase 1 (soluble)
GPR15 G protein-coupled receptor 15
GPX3 glutathione peroxidase 3
GUCA1B guanylate cyclase activator 1B (retina)
GYPB glycophorin B (MNS blood group)
HAL histidine ammonia-lyase
HAMP hepcidin antimicrobial peptide
HIST1H2AL histone cluster 1, H2al
IGHA1 immunoglobulin heavy constant alpha 1
IL10RA interleukin 10 receptor, alpha
JAG1 jagged 1
JPH3 junctophilin 3
KIDINS220 kinase D-interacting substrate, 220kDa
KITLG KIT ligand
KLHL11 kelch-like family member 11
KLK13 kallikrein-related peptidase 13
LAIR1 leukocyte-associated immunoglobulin-like receptor 1
LIME1 Lck interacting transmembrane adaptor 1
LTBP4 latent transforming growth factor beta binding protein 4
LTK leukocyte receptor tyrosine kinase
MAPK8IP3 mitogen-activated protein kinase 8 interacting protein 3
MAU2 MAU2 sister chromatid cohesion factor
MC2R melanocortin 2 receptor (adrenocorticotropic hormone)
METTL16 methyltransferase like 16
MGC2889 uncharacterized protein MGC2889
MUC5AC mucin 5AC, oligomeric mucus/gel-forming
NAALAD2 N-acetylated alpha-linked acidic dipeptidase 2
NCLN nicalin
NDRG2 NDRG family member 2
NPFF neuropeptide FF-amide peptide precursor
NPPB natriuretic peptide B
PAX4 paired box 4
PCDHGA3 protocadherin gamma subfamily A, 3
PDE4A phosphodiesterase 4A, cAMP-specific
PLD1 phospholipase D1, phosphatidylcholine-specific
PODXL2 podocalyxin-like 2
POU2F2 POU class 2 homeobox 2
PPP3R1 protein phosphatase 3, regulatory subunit B, alpha
PSG4 pregnancy specific beta-1-glycoprotein 4
PTGIS prostaglandin I2 (prostacyclin) synthase
RAB11FIP3 RAB11 family interacting protein 3 (class II)
RAB6A RAB6A, member RAS oncogene family
RB1 retinoblastoma 1
RPS14 ribosomal protein S14
SLC22A7 solute carrier family 22 (organic anion transporter), member 7
SLC39A2 solute carrier family 39 (zinc transporter), member 2
SMG7 SMG7 nonsense mediated mRNA decay factor
SOS2 son of sevenless homolog 2 (Drosophila)
SP110 SP110 nuclear body protein
SPHK2 sphingosine kinase 2
SRP72 signal recognition particle 72kDa
STK16 serine/threonine kinase 16
TBX21 T-box 21
TMEM246 transmembrane protein 246
TMPRSS11D transmembrane protease, serine 11D
TTC38 tetratricopeptide repeat domain 38
TTC9 tetratricopeptide repeat domain 9
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
USP22 ubiquitin specific peptidase 22
UTY ubiquitously transcribed tetratricopeptide repeat containing, Y-linked
YIF1B Yip1 interacting factor homolog B (S. cerevisiae)
ZCCHC4 zinc finger, CCHC domain containing 4
ZNF440 zinc finger protein 440

decreased expression

Symbol Name
ACADS acyl-CoA dehydrogenase, C-2 to C-3 short chain
ACSS3 acyl-CoA synthetase short-chain family member 3
ADGRE2 adhesion G protein-coupled receptor E2
AKAP5 A kinase (PRKA) anchor protein 5
ARID3B AT rich interactive domain 3B (BRIGHT-like)
ARPIN actin-related protein 2/3 complex inhibitor
ATP1A3 ATPase, Na+/K+ transporting, alpha 3 polypeptide
B3GALT4 UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 4
BBC3 BCL2 binding component 3
C3 complement component 3
C4ORF29 chromosome 4 open reading frame 29
CAMKMT calmodulin-lysine N-methyltransferase
CLSTN3 calsyntenin 3
COBL cordon-bleu WH2 repeat protein
COPZ2 coatomer protein complex, subunit zeta 2
COX6A2 cytochrome c oxidase subunit VIa polypeptide 2
CPED1 cadherin-like and PC-esterase domain containing 1
CYTH3 cytohesin 3
DBF4B DBF4 zinc finger B
DDX51 DEAD (Asp-Glu-Ala-Asp) box polypeptide 51
DMTN dematin actin binding protein
DTX2 deltex 2, E3 ubiquitin ligase
DUSP9 dual specificity phosphatase 9
EFNA3 ephrin-A3
EPN1 epsin 1
ERN2 endoplasmic reticulum to nucleus signaling 2
EXD3 exonuclease 3'-5' domain containing 3
FAM63B family with sequence similarity 63, member B
FGL1 fibrinogen-like 1
FKRP fukutin related protein
GABRB2 gamma-aminobutyric acid (GABA) A receptor, beta 2
GINS4 GINS complex subunit 4 (Sld5 homolog)
GLB1L galactosidase, beta 1-like
GNG7 guanine nucleotide binding protein (G protein), gamma 7
GPR21 G protein-coupled receptor 21
GPRIN2 G protein regulated inducer of neurite outgrowth 2
GREB1L growth regulation by estrogen in breast cancer-like
GUSBP3 glucuronidase, beta pseudogene 3
HIST1H2AK histone cluster 1, H2ak
IFNA17 interferon, alpha 17
IL1RAPL2 interleukin 1 receptor accessory protein-like 2
INO80D INO80 complex subunit D
KCTD15 potassium channel tetramerization domain containing 15
KIAA0319L KIAA0319-like
KIFC3 kinesin family member C3
KLHL25 kelch-like family member 25
KRT34 keratin 34, type I
KRT4 keratin 4, type II
LIMD2 LIM domain containing 2
LRRC37A3 leucine rich repeat containing 37, member A3
LYL1 lymphoblastic leukemia associated hematopoiesis regulator 1
MAP2 microtubule-associated protein 2
MARK1 MAP/microtubule affinity-regulating kinase 1
MMP10 matrix metallopeptidase 10
MMP2 matrix metallopeptidase 2
NDNF neuron-derived neurotrophic factor
NFKBIL1 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1
NOL12 nucleolar protein 12
NTNG1 netrin G1
OLFML2B olfactomedin-like 2B
OR7E156P olfactory receptor, family 7, subfamily E, member 156 pseudogene
PENK proenkephalin
PLEKHB1 pleckstrin homology domain containing, family B (evectins) member 1
PMCHL1 pro-melanin-concentrating hormone-like 1, pseudogene
PRB3 proline-rich protein BstNI subfamily 3
PREX2 phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2
PRF1 perforin 1 (pore forming protein)
PRRG4 proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane)
PSMB9 proteasome (prosome, macropain) subunit, beta type, 9
RIBC2 RIB43A domain with coiled-coils 2
RNF125 ring finger protein 125, E3 ubiquitin protein ligase
RPH3A rabphilin 3A
SCAMP5 secretory carrier membrane protein 5
SCD5 stearoyl-CoA desaturase 5
SEC61A2 Sec61 alpha 2 subunit (S. cerevisiae)
SETD1A SET domain containing 1A
SH3TC1 SH3 domain and tetratricopeptide repeats 1
SLC35F5 solute carrier family 35, member F5
SULT2B1 sulfotransferase family, cytosolic, 2B, member 1
SUZ12P1 suppressor of zeste 12 homolog pseudogene 1
TFCP2L1 transcription factor CP2-like 1
TIMM50 translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae)
TMEM180 transmembrane protein 180
TUBB2B tubulin, beta 2B class IIb
VGF VGF nerve growth factor inducible
XPNPEP3 X-prolyl aminopeptidase 3, mitochondrial
ZFHX2 zinc finger homeobox 2
ZNF155 zinc finger protein 155
ZNF222 zinc finger protein 222
ZNF225 zinc finger protein 225
ZNF234 zinc finger protein 234
ZNF264 zinc finger protein 264
ZNF442 zinc finger protein 442
ZNF446 zinc finger protein 446
ZNF611 zinc finger protein 611
ZNF652 zinc finger protein 652
ZNF721 zinc finger protein 721