thiamazole-3898 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the thiamazole-3898 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACACA acetyl-CoA carboxylase alpha
ACRV1 acrosomal vesicle protein 1
ADGRA2 adhesion G protein-coupled receptor A2
ALCAM activated leukocyte cell adhesion molecule
ARVCF armadillo repeat gene deleted in velocardiofacial syndrome
ATAT1 alpha tubulin acetyltransferase 1
ATP8B1 ATPase, aminophospholipid transporter, class I, type 8B, member 1
BCL9 B-cell CLL/lymphoma 9
BGN biglycan
BMP15 bone morphogenetic protein 15
BMP5 bone morphogenetic protein 5
BUB1 BUB1 mitotic checkpoint serine/threonine kinase
C10ORF12 chromosome 10 open reading frame 12
C21ORF2 chromosome 21 open reading frame 2
C8ORF4 chromosome 8 open reading frame 4
CAPZB capping protein (actin filament) muscle Z-line, beta
CARF calcium responsive transcription factor
CDC42 cell division cycle 42
CDK3 cyclin-dependent kinase 3
CDR2L cerebellar degeneration-related protein 2-like
CELP carboxyl ester lipase pseudogene
CEP41 centrosomal protein 41kDa
CFAP45 cilia and flagella associated protein 45
CREBBP CREB binding protein
CRMP1 collapsin response mediator protein 1
CTAGE5 CTAGE family, member 5
DCBLD2 discoidin, CUB and LCCL domain containing 2
DNPH1 2'-deoxynucleoside 5'-phosphate N-hydrolase 1
DOCK9 dedicator of cytokinesis 9
DRD2 dopamine receptor D2
ELP6 elongator acetyltransferase complex subunit 6
ERN1 endoplasmic reticulum to nucleus signaling 1
ESR1 estrogen receptor 1
EYA3 EYA transcriptional coactivator and phosphatase 3
F13A1 coagulation factor XIII, A1 polypeptide
FAM212B family with sequence similarity 212, member B
FEZ1 fasciculation and elongation protein zeta 1 (zygin I)
GPR137 G protein-coupled receptor 137
GSK3A glycogen synthase kinase 3 alpha
GUSBP3 glucuronidase, beta pseudogene 3
H6PD hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase)
HEY2 hes-related family bHLH transcription factor with YRPW motif 2
HIST1H4E histone cluster 1, H4e
HNRNPM heterogeneous nuclear ribonucleoprotein M
IGSF6 immunoglobulin superfamily, member 6
INO80D INO80 complex subunit D
KIAA0368 KIAA0368
KIF25 kinesin family member 25
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
KLHL28 kelch-like family member 28
KLRAP1 killer cell lectin-like receptor subfamily A pseudogene 1
LAT2 linker for activation of T cells family, member 2
LMO1 LIM domain only 1 (rhombotin 1)
MAPK11 mitogen-activated protein kinase 11
METTL7A methyltransferase like 7A
MINK1 misshapen-like kinase 1
MMP11 matrix metallopeptidase 11
MMP13 matrix metallopeptidase 13
MTL5 metallothionein-like 5, testis-specific (tesmin)
NEUROD4 neuronal differentiation 4
NFKBIB nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
NPR3 natriuretic peptide receptor 3
NR2F1 nuclear receptor subfamily 2, group F, member 1
NRP2 neuropilin 2
NT5DC3 5'-nucleotidase domain containing 3
NUDT11 nudix (nucleoside diphosphate linked moiety X)-type motif 11
PARVA parvin, alpha
PAX8 paired box 8
PCDHGA3 protocadherin gamma subfamily A, 3
PDE12 phosphodiesterase 12
PEG10 paternally expressed 10
PFKFB1 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1
PIP5K1A phosphatidylinositol-4-phosphate 5-kinase, type I, alpha
PLIN2 perilipin 2
PPP1R14D protein phosphatase 1, regulatory (inhibitor) subunit 14D
PQLC2 PQ loop repeat containing 2
PQLC3 PQ loop repeat containing 3
RAB40C RAB40C, member RAS oncogene family
REEP2 receptor accessory protein 2
RNF126P1 ring finger protein 126 pseudogene 1
RPL10L ribosomal protein L10-like
SAA4 serum amyloid A4, constitutive
SIRT5 sirtuin 5
SLC52A1 solute carrier family 52 (riboflavin transporter), member 1
THTPA thiamine triphosphatase
TMOD1 tropomodulin 1
TNFSF18 tumor necrosis factor (ligand) superfamily, member 18
TNKS tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase
TPSG1 tryptase gamma 1
TRO trophinin
TRPV1 transient receptor potential cation channel, subfamily V, member 1
TTC39A tetratricopeptide repeat domain 39A
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
USP2 ubiquitin specific peptidase 2
VPS45 vacuolar protein sorting 45 homolog (S. cerevisiae)
ZC2HC1C zinc finger, C2HC-type containing 1C
ZNF224 zinc finger protein 224
ZSCAN32 zinc finger and SCAN domain containing 32

decreased expression

Symbol Name
ACBD4 acyl-CoA binding domain containing 4
AFAP1 actin filament associated protein 1
AKR1B1 aldo-keto reductase family 1, member B1 (aldose reductase)
ATP6V0A4 ATPase, H+ transporting, lysosomal V0 subunit a4
BBC3 BCL2 binding component 3
BST2 bone marrow stromal cell antigen 2
C1ORF56 chromosome 1 open reading frame 56
C3 complement component 3
C5AR2 complement component 5a receptor 2
CAMKMT calmodulin-lysine N-methyltransferase
CCNK cyclin K
CD3D CD3d molecule, delta (CD3-TCR complex)
CD82 CD82 molecule
CFHR4 complement factor H-related 4
CKMT2 creatine kinase, mitochondrial 2 (sarcomeric)
CNR2 cannabinoid receptor 2 (macrophage)
CSF1R colony stimulating factor 1 receptor
CYP17A1 cytochrome P450, family 17, subfamily A, polypeptide 1
CYP2B7P cytochrome P450, family 2, subfamily B, polypeptide 7, pseudogene
DAAM2 dishevelled associated activator of morphogenesis 2
DAGLA diacylglycerol lipase, alpha
DEF6 differentially expressed in FDCP 6 homolog (mouse)
DNAJC28 DnaJ (Hsp40) homolog, subfamily C, member 28
DPY19L1P1 DPY19L1 pseudogene 1
ERN2 endoplasmic reticulum to nucleus signaling 2
FAT4 FAT atypical cadherin 4
GALR2 galanin receptor 2
GBP2 guanylate binding protein 2, interferon-inducible
GCNT2 glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group)
GJA9 gap junction protein, alpha 9, 59kDa
GLDC glycine dehydrogenase (decarboxylating)
GNAT2 guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 2
GNG3 guanine nucleotide binding protein (G protein), gamma 3
GPR157 G protein-coupled receptor 157
GPRC5D G protein-coupled receptor, class C, group 5, member D
GPRIN2 G protein regulated inducer of neurite outgrowth 2
GPT glutamic-pyruvate transaminase (alanine aminotransferase)
GSTM2 glutathione S-transferase mu 2 (muscle)
HIST1H1D histone cluster 1, H1d
HIST1H2BM histone cluster 1, H2bm
HIST2H2AA3 histone cluster 2, H2aa3
HIVEP3 human immunodeficiency virus type I enhancer binding protein 3
HOXA1 homeobox A1
HS3ST3A1 heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1
HSF4 heat shock transcription factor 4
HTR1E 5-hydroxytryptamine (serotonin) receptor 1E, G protein-coupled
IL12RB1 interleukin 12 receptor, beta 1
ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)
KCNS1 potassium voltage-gated channel, modifier subfamily S, member 1
KIAA0125 KIAA0125
KIAA1107 KIAA1107
KLK8 kallikrein-related peptidase 8
KRT15 keratin 15, type I
LOC729164 hCG1732469
MATK megakaryocyte-associated tyrosine kinase
MCC mutated in colorectal cancers
MFSD6 major facilitator superfamily domain containing 6
NBR2 neighbor of BRCA1 gene 2 (non-protein coding)
NCALD neurocalcin delta
NEURL1 neuralized E3 ubiquitin protein ligase 1
NIPSNAP3B nipsnap homolog 3B (C. elegans)
NKX3-2 NK3 homeobox 2
NLRX1 NLR family member X1
NPFFR1 neuropeptide FF receptor 1
PAX9 paired box 9
PCDHB13 protocadherin beta 13
PIGQ phosphatidylinositol glycan anchor biosynthesis, class Q
PLD2 phospholipase D2
PLEKHA6 pleckstrin homology domain containing, family A member 6
PLEKHF1 pleckstrin homology domain containing, family F (with FYVE domain) member 1
PPP1R9A protein phosphatase 1, regulatory subunit 9A
PPT2 palmitoyl-protein thioesterase 2
RAB3IL1 RAB3A interacting protein (rabin3)-like 1
RNF39 ring finger protein 39
ROM1 retinal outer segment membrane protein 1
RPL23AP32 ribosomal protein L23a pseudogene 32
SCARA3 scavenger receptor class A, member 3
SECTM1 secreted and transmembrane 1
SERPINB5 serpin peptidase inhibitor, clade B (ovalbumin), member 5
SERPINB8 serpin peptidase inhibitor, clade B (ovalbumin), member 8
SLC41A3 solute carrier family 41, member 3
SLC7A9 solute carrier family 7 (amino acid transporter light chain, bo,+ system), member 9
SPTBN2 spectrin, beta, non-erythrocytic 2
TCTN2 tectonic family member 2
TFDP3 transcription factor Dp family, member 3
THRB thyroid hormone receptor, beta
TNFSF9 tumor necrosis factor (ligand) superfamily, member 9
TNNT2 troponin T type 2 (cardiac)
TRPV6 transient receptor potential cation channel, subfamily V, member 6
TTLL1 tubulin tyrosine ligase-like family member 1
UPK2 uroplakin 2
VASH1 vasohibin 1
VEGFB vascular endothelial growth factor B
WLS wntless Wnt ligand secretion mediator
WNT16 wingless-type MMTV integration site family, member 16
XAB2 XPA binding protein 2
ZNF205 zinc finger protein 205
ZNF639 zinc finger protein 639
ZNF701 zinc finger protein 701
ZNF76 zinc finger protein 76