| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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194 genes differentially expressed following the thiamazole-4550 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ADAP2 | ArfGAP with dual PH domains 2 |
| ADGRL3 | adhesion G protein-coupled receptor L3 |
| ADGRV1 | adhesion G protein-coupled receptor V1 |
| AKR1C2 | aldo-keto reductase family 1, member C2 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 |
| ATP2C2 | ATPase, Ca++ transporting, type 2C, member 2 |
| ATP6V0A2 | ATPase, H+ transporting, lysosomal V0 subunit a2 |
| B3GNT3 | UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3 |
| BTG2 | BTG family, member 2 |
| C14ORF79 | chromosome 14 open reading frame 79 |
| C17ORF53 | chromosome 17 open reading frame 53 |
| C8ORF44 | chromosome 8 open reading frame 44 |
| CACNA2D1 | calcium channel, voltage-dependent, alpha 2/delta subunit 1 |
| CBL | Cbl proto-oncogene, E3 ubiquitin protein ligase |
| CCNO | cyclin O |
| CEP295 | centrosomal protein 295kDa |
| CFAP45 | cilia and flagella associated protein 45 |
| CLCN4 | chloride channel, voltage-sensitive 4 |
| CLTA | clathrin, light chain A |
| CPS1 | carbamoyl-phosphate synthase 1, mitochondrial |
| CUL7 | cullin 7 |
| CXORF21 | chromosome X open reading frame 21 |
| CYP24A1 | cytochrome P450, family 24, subfamily A, polypeptide 1 |
| DGCR2 | DiGeorge syndrome critical region gene 2 |
| DHX34 | DEAH (Asp-Glu-Ala-His) box polypeptide 34 |
| DSTYK | dual serine/threonine and tyrosine protein kinase |
| EMC3 | ER membrane protein complex subunit 3 |
| ERAP1 | endoplasmic reticulum aminopeptidase 1 |
| FBXO31 | F-box protein 31 |
| FGFR4 | fibroblast growth factor receptor 4 |
| FMNL1 | formin-like 1 |
| FRMD4B | FERM domain containing 4B |
| GAB1 | GRB2-associated binding protein 1 |
| GALNT14 | polypeptide N-acetylgalactosaminyltransferase 14 |
| GFOD2 | glucose-fructose oxidoreductase domain containing 2 |
| GNG4 | guanine nucleotide binding protein (G protein), gamma 4 |
| GPER1 | G protein-coupled estrogen receptor 1 |
| GPNMB | glycoprotein (transmembrane) nmb |
| GSK3A | glycogen synthase kinase 3 alpha |
| GZMK | granzyme K (granzyme 3; tryptase II) |
| ICOSLG | inducible T-cell co-stimulator ligand |
| ID4 | inhibitor of DNA binding 4, dominant negative helix-loop-helix protein |
| IKZF4 | IKAROS family zinc finger 4 (Eos) |
| IL15 | interleukin 15 |
| JAK2 | Janus kinase 2 |
| KCNJ5 | potassium channel, inwardly rectifying subfamily J, member 5 |
| LAMP1 | lysosomal-associated membrane protein 1 |
| LIG3 | ligase III, DNA, ATP-dependent |
| MAGEA12 | melanoma antigen family A12 |
| MAP2K7 | mitogen-activated protein kinase kinase 7 |
| MAPK11 | mitogen-activated protein kinase 11 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase |
| MLLT3 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3 |
| MTHFR | methylenetetrahydrofolate reductase (NAD(P)H) |
| NF1 | neurofibromin 1 |
| NGF | nerve growth factor (beta polypeptide) |
| NRG2 | neuregulin 2 |
| P2RY1 | purinergic receptor P2Y, G-protein coupled, 1 |
| PBXIP1 | pre-B-cell leukemia homeobox interacting protein 1 |
| PCYT1A | phosphate cytidylyltransferase 1, choline, alpha |
| PDCD2 | programmed cell death 2 |
| PDK3 | pyruvate dehydrogenase kinase, isozyme 3 |
| PDPR | pyruvate dehydrogenase phosphatase regulatory subunit |
| POU5F1B | POU class 5 homeobox 1B |
| PRKAR1B | protein kinase, cAMP-dependent, regulatory, type I, beta |
| PRKG2 | protein kinase, cGMP-dependent, type II |
| PRPH | peripherin |
| RAB11B | RAB11B, member RAS oncogene family |
| RAD51B | RAD51 paralog B |
| RNGTT | RNA guanylyltransferase and 5'-phosphatase |
| RPL23AP53 | ribosomal protein L23a pseudogene 53 |
| RRP12 | ribosomal RNA processing 12 homolog (S. cerevisiae) |
| SAFB2 | scaffold attachment factor B2 |
| SCARB1 | scavenger receptor class B, member 1 |
| SHOX2 | short stature homeobox 2 |
| SLAMF7 | SLAM family member 7 |
| SLC35D1 | solute carrier family 35 (UDP-GlcA/UDP-GalNAc transporter), member D1 |
| SLC48A1 | solute carrier family 48 (heme transporter), member 1 |
| SLC4A4 | solute carrier family 4 (sodium bicarbonate cotransporter), member 4 |
| SMO | smoothened, frizzled class receptor |
| SRGAP3 | SLIT-ROBO Rho GTPase activating protein 3 |
| STRN | striatin, calmodulin binding protein |
| STS | steroid sulfatase (microsomal), isozyme S |
| TLDC1 | TBC/LysM-associated domain containing 1 |
| TLN2 | talin 2 |
| TMEM212 | transmembrane protein 212 |
| TNIK | TRAF2 and NCK interacting kinase |
| TOP3B | topoisomerase (DNA) III beta |
| TPM2 | tropomyosin 2 (beta) |
| TTC12 | tetratricopeptide repeat domain 12 |
| UBE2B | ubiquitin-conjugating enzyme E2B |
| ZFPL1 | zinc finger protein-like 1 |
| ZNF141 | zinc finger protein 141 |
| ZNF440 | zinc finger protein 440 |
| ZNF573 | zinc finger protein 573 |
| ZNF589 | zinc finger protein 589 |
| ZNF614 | zinc finger protein 614 |
| Symbol | Name |
|---|---|
| A1CF | APOBEC1 complementation factor |
| ABCA7 | ATP-binding cassette, sub-family A (ABC1), member 7 |
| ABHD17B | abhydrolase domain containing 17B |
| AKAP5 | A kinase (PRKA) anchor protein 5 |
| ANXA2P1 | annexin A2 pseudogene 1 |
| ARHGEF26 | Rho guanine nucleotide exchange factor (GEF) 26 |
| ARL14 | ADP-ribosylation factor-like 14 |
| ARRB2 | arrestin, beta 2 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) |
| ATP7B | ATPase, Cu++ transporting, beta polypeptide |
| BTF3P12 | basic transcription factor 3 pseudogene 12 |
| C11ORF63 | chromosome 11 open reading frame 63 |
| C17ORF70 | chromosome 17 open reading frame 70 |
| C19ORF40 | chromosome 19 open reading frame 40 |
| C9ORF40 | chromosome 9 open reading frame 40 |
| CAPN15 | calpain 15 |
| CCNE1 | cyclin E1 |
| CD101 | CD101 molecule |
| CD68 | CD68 molecule |
| CDH10 | cadherin 10, type 2 (T2-cadherin) |
| CNTLN | centlein, centrosomal protein |
| CPED1 | cadherin-like and PC-esterase domain containing 1 |
| DCUN1D2 | DCN1, defective in cullin neddylation 1, domain containing 2 |
| DUSP8 | dual specificity phosphatase 8 |
| ERN2 | endoplasmic reticulum to nucleus signaling 2 |
| EVPL | envoplakin |
| FAM186A | family with sequence similarity 186, member A |
| FBRS | fibrosin |
| FOXC1 | forkhead box C1 |
| GJA8 | gap junction protein, alpha 8, 50kDa |
| GPR1 | G protein-coupled receptor 1 |
| GRTP1 | growth hormone regulated TBC protein 1 |
| HIST1H1D | histone cluster 1, H1d |
| HIST1H2AK | histone cluster 1, H2ak |
| HIST1H2BO | histone cluster 1, H2bo |
| HMHA1 | histocompatibility (minor) HA-1 |
| HOXA7 | homeobox A7 |
| HOXC8 | homeobox C8 |
| IL17RB | interleukin 17 receptor B |
| IPO8 | importin 8 |
| IQSEC2 | IQ motif and Sec7 domain 2 |
| ITGB2 | integrin, beta 2 (complement component 3 receptor 3 and 4 subunit) |
| KRT75 | keratin 75, type II |
| KRT86 | keratin 86, type II |
| LAX1 | lymphocyte transmembrane adaptor 1 |
| LOC729164 | hCG1732469 |
| MAGEH1 | melanoma antigen family H1 |
| MICAL1 | microtubule associated monooxygenase, calponin and LIM domain containing 1 |
| MOCS3 | molybdenum cofactor synthesis 3 |
| MTA2 | metastasis associated 1 family, member 2 |
| MTHFSD | methenyltetrahydrofolate synthetase domain containing |
| MX1 | MX dynamin-like GTPase 1 |
| NARFL | nuclear prelamin A recognition factor-like |
| NAT6 | N-acetyltransferase 6 (GCN5-related) |
| NID2 | nidogen 2 (osteonidogen) |
| NPFFR1 | neuropeptide FF receptor 1 |
| NPM3 | nucleophosmin/nucleoplasmin 3 |
| OR2F1 | olfactory receptor, family 2, subfamily F, member 1 (gene/pseudogene) |
| ORAI3 | ORAI calcium release-activated calcium modulator 3 |
| PALM | paralemmin |
| PCDHGB5 | protocadherin gamma subfamily B, 5 |
| PDE6C | phosphodiesterase 6C, cGMP-specific, cone, alpha prime |
| PLAC8 | placenta-specific 8 |
| POM121 | POM121 transmembrane nucleoporin |
| PPT2 | palmitoyl-protein thioesterase 2 |
| PRB3 | proline-rich protein BstNI subfamily 3 |
| PRR14L | proline rich 14-like |
| PRSS53 | protease, serine, 53 |
| PRSS8 | protease, serine, 8 |
| RBFOX1 | RNA binding protein, fox-1 homolog (C. elegans) 1 |
| RELB | v-rel avian reticuloendotheliosis viral oncogene homolog B |
| RNF122 | ring finger protein 122 |
| RPRM | reprimo, TP53 dependent G2 arrest mediator candidate |
| RUNX1-IT1 | RUNX1 intronic transcript 1 |
| SARS2 | seryl-tRNA synthetase 2, mitochondrial |
| SCUBE3 | signal peptide, CUB domain, EGF-like 3 |
| SH3GL2 | SH3-domain GRB2-like 2 |
| SLC12A7 | solute carrier family 12 (potassium/chloride transporter), member 7 |
| SLC3A1 | solute carrier family 3 (amino acid transporter heavy chain), member 1 |
| SLMO1 | slowmo homolog 1 (Drosophila) |
| SMARCD3 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3 |
| SMPDL3B | sphingomyelin phosphodiesterase, acid-like 3B |
| SPTLC3 | serine palmitoyltransferase, long chain base subunit 3 |
| SRD5A3 | steroid 5 alpha-reductase 3 |
| SUGCT | succinyl-CoA:glutarate-CoA transferase |
| SYNGR3 | synaptogyrin 3 |
| TNFRSF8 | tumor necrosis factor receptor superfamily, member 8 |
| TRIM21 | tripartite motif containing 21 |
| TRIM66 | tripartite motif containing 66 |
| TTLL1 | tubulin tyrosine ligase-like family member 1 |
| TUT1 | terminal uridylyl transferase 1, U6 snRNA-specific |
| USB1 | U6 snRNA biogenesis 1 |
| USP32 | ubiquitin specific peptidase 32 |
| YOD1 | YOD1 deubiquitinase |
| ZC3H12A | zinc finger CCCH-type containing 12A |
| ZNF37BP | zinc finger protein 37B, pseudogene |
| ZNF41 | zinc finger protein 41 |
