| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
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198 genes differentially expressed following the thiamine-2894 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| A2M | alpha-2-macroglobulin |
| ABCC3 | ATP-binding cassette, sub-family C (CFTR/MRP), member 3 |
| ALCAM | activated leukocyte cell adhesion molecule |
| ANP32C | acidic (leucine-rich) nuclear phosphoprotein 32 family, member C |
| ARAP1 | ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 |
| ASCL1 | achaete-scute family bHLH transcription factor 1 |
| ASIC1 | acid sensing (proton gated) ion channel 1 |
| ATP11A | ATPase, class VI, type 11A |
| BIRC3 | baculoviral IAP repeat containing 3 |
| BRF1 | BRF1, RNA polymerase III transcription initiation factor 90 kDa subunit |
| BTBD7 | BTB (POZ) domain containing 7 |
| BTNL3 | butyrophilin-like 3 |
| C8ORF60 | chromosome 8 open reading frame 60 |
| CA4 | carbonic anhydrase IV |
| CACNA1H | calcium channel, voltage-dependent, T type, alpha 1H subunit |
| CACNB2 | calcium channel, voltage-dependent, beta 2 subunit |
| CCL27 | chemokine (C-C motif) ligand 27 |
| CDADC1 | cytidine and dCMP deaminase domain containing 1 |
| CDK13 | cyclin-dependent kinase 13 |
| CEP295 | centrosomal protein 295kDa |
| CES1 | carboxylesterase 1 |
| CES3 | carboxylesterase 3 |
| CHI3L2 | chitinase 3-like 2 |
| CHN2 | chimerin 2 |
| CLTA | clathrin, light chain A |
| COX6A2 | cytochrome c oxidase subunit VIa polypeptide 2 |
| CT62 | cancer/testis antigen 62 |
| DAPK2 | death-associated protein kinase 2 |
| DCAF13 | DDB1 and CUL4 associated factor 13 |
| DDX51 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 51 |
| DNMT3A | DNA (cytosine-5-)-methyltransferase 3 alpha |
| DYNC1LI2 | dynein, cytoplasmic 1, light intermediate chain 2 |
| FBXO21 | F-box protein 21 |
| FXYD5 | FXYD domain containing ion transport regulator 5 |
| GM2A | GM2 ganglioside activator |
| GNRHR | gonadotropin-releasing hormone receptor |
| GPATCH4 | G patch domain containing 4 |
| GPR107 | G protein-coupled receptor 107 |
| GYG2 | glycogenin 2 |
| HAP1 | huntingtin-associated protein 1 |
| IL4R | interleukin 4 receptor |
| ITM2C | integral membrane protein 2C |
| JAKMIP2 | janus kinase and microtubule interacting protein 2 |
| KCTD17 | potassium channel tetramerization domain containing 17 |
| KRT15 | keratin 15, type I |
| LAIR2 | leukocyte-associated immunoglobulin-like receptor 2 |
| LMO2 | LIM domain only 2 (rhombotin-like 1) |
| LTC4S | leukotriene C4 synthase |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 |
| MBNL2 | muscleblind-like splicing regulator 2 |
| MMP3 | matrix metallopeptidase 3 |
| MYO1B | myosin IB |
| N4BP3 | NEDD4 binding protein 3 |
| NEK11 | NIMA-related kinase 11 |
| NF1 | neurofibromin 1 |
| NFKB2 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100) |
| NT5M | 5',3'-nucleotidase, mitochondrial |
| NUMA1 | nuclear mitotic apparatus protein 1 |
| OXCT2 | 3-oxoacid CoA transferase 2 |
| PCDHB11 | protocadherin beta 11 |
| PHF20L1 | PHD finger protein 20-like 1 |
| PHKA2 | phosphorylase kinase, alpha 2 (liver) |
| R3HDM1 | R3H domain containing 1 |
| RAB40C | RAB40C, member RAS oncogene family |
| RABGAP1L | RAB GTPase activating protein 1-like |
| RANBP3 | RAN binding protein 3 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats |
| RND1 | Rho family GTPase 1 |
| RQCD1 | RCD1 required for cell differentiation1 homolog (S. pombe) |
| RREB1 | ras responsive element binding protein 1 |
| SAG | S-antigen; retina and pineal gland (arrestin) |
| SGCD | sarcoglycan, delta (35kDa dystrophin-associated glycoprotein) |
| SH3BP2 | SH3-domain binding protein 2 |
| SLC1A4 | solute carrier family 1 (glutamate/neutral amino acid transporter), member 4 |
| SLC24A1 | solute carrier family 24 (sodium/potassium/calcium exchanger), member 1 |
| SNCG | synuclein, gamma (breast cancer-specific protein 1) |
| SOCS3 | suppressor of cytokine signaling 3 |
| STIM1 | stromal interaction molecule 1 |
| TAT | tyrosine aminotransferase |
| TFAP2A | transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha) |
| TFEB | transcription factor EB |
| THBS1 | thrombospondin 1 |
| TLE2 | transducin-like enhancer of split 2 |
| TMCC2 | transmembrane and coiled-coil domain family 2 |
| TMLHE | trimethyllysine hydroxylase, epsilon |
| TNFRSF8 | tumor necrosis factor receptor superfamily, member 8 |
| TNFRSF9 | tumor necrosis factor receptor superfamily, member 9 |
| TOR4A | torsin family 4, member A |
| UPK2 | uroplakin 2 |
| WFDC2 | WAP four-disulfide core domain 2 |
| WNT16 | wingless-type MMTV integration site family, member 16 |
| WTAP | Wilms tumor 1 associated protein |
| ZFP36L2 | ZFP36 ring finger protein-like 2 |
| ZKSCAN8 | zinc finger with KRAB and SCAN domains 8 |
| ZNF446 | zinc finger protein 446 |
| ZNF552 | zinc finger protein 552 |
| ZNF76 | zinc finger protein 76 |
| Symbol | Name |
|---|---|
| ABCC2 | ATP-binding cassette, sub-family C (CFTR/MRP), member 2 |
| ALG12 | ALG12, alpha-1,6-mannosyltransferase |
| ALPK1 | alpha-kinase 1 |
| APOLD1 | apolipoprotein L domain containing 1 |
| ARHGDIG | Rho GDP dissociation inhibitor (GDI) gamma |
| ARHGEF1 | Rho guanine nucleotide exchange factor (GEF) 1 |
| ARSB | arylsulfatase B |
| ASIC3 | acid sensing (proton gated) ion channel 3 |
| BAP1 | BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase) |
| C14ORF93 | chromosome 14 open reading frame 93 |
| C1QTNF3 | C1q and tumor necrosis factor related protein 3 |
| CAPN15 | calpain 15 |
| CAPN5 | calpain 5 |
| CBX8 | chromobox homolog 8 |
| CDK20 | cyclin-dependent kinase 20 |
| CFAP70 | cilia and flagella associated protein 70 |
| CLCF1 | cardiotrophin-like cytokine factor 1 |
| CLSTN2 | calsyntenin 2 |
| CNR2 | cannabinoid receptor 2 (macrophage) |
| CTAGE9 | CTAGE family, member 9 |
| CTRL | chymotrypsin-like |
| DGKE | diacylglycerol kinase, epsilon 64kDa |
| EFNA3 | ephrin-A3 |
| EPB41L5 | erythrocyte membrane protein band 4.1 like 5 |
| FAM46C | family with sequence similarity 46, member C |
| FAM76A | family with sequence similarity 76, member A |
| FBXO4 | F-box protein 4 |
| FFAR2 | free fatty acid receptor 2 |
| FRK | fyn-related Src family tyrosine kinase |
| GADD45G | growth arrest and DNA-damage-inducible, gamma |
| GPRIN2 | G protein regulated inducer of neurite outgrowth 2 |
| GSTA4 | glutathione S-transferase alpha 4 |
| HOXC11 | homeobox C11 |
| HOXC4 | homeobox C4 |
| IQCC | IQ motif containing C |
| IRF2BP1 | interferon regulatory factor 2 binding protein 1 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) |
| ITPKB | inositol-trisphosphate 3-kinase B |
| KBTBD11 | kelch repeat and BTB (POZ) domain containing 11 |
| KDM5C | lysine (K)-specific demethylase 5C |
| KIAA0319L | KIAA0319-like |
| LIME1 | Lck interacting transmembrane adaptor 1 |
| LMCD1 | LIM and cysteine-rich domains 1 |
| LRRC61 | leucine rich repeat containing 61 |
| LYL1 | lymphoblastic leukemia associated hematopoiesis regulator 1 |
| LZTS3 | leucine zipper, putative tumor suppressor family member 3 |
| MAPK10 | mitogen-activated protein kinase 10 |
| MBTD1 | mbt domain containing 1 |
| MED24 | mediator complex subunit 24 |
| MITF | microphthalmia-associated transcription factor |
| MYOZ3 | myozenin 3 |
| NAV2 | neuron navigator 2 |
| NFKBIB | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta |
| NME5 | NME/NM23 family member 5 |
| NOD1 | nucleotide-binding oligomerization domain containing 1 |
| NOL10 | nucleolar protein 10 |
| OAS3 | 2'-5'-oligoadenylate synthetase 3, 100kDa |
| OVOL1 | ovo-like zinc finger 1 |
| PDE12 | phosphodiesterase 12 |
| PIP5K1C | phosphatidylinositol-4-phosphate 5-kinase, type I, gamma |
| PNPLA6 | patatin-like phospholipase domain containing 6 |
| PTPRU | protein tyrosine phosphatase, receptor type, U |
| PYCRL | pyrroline-5-carboxylate reductase-like |
| QSER1 | glutamine and serine rich 1 |
| RAB11FIP5 | RAB11 family interacting protein 5 (class I) |
| RAB3A | RAB3A, member RAS oncogene family |
| RASL11B | RAS-like, family 11, member B |
| RETN | resistin |
| RNF39 | ring finger protein 39 |
| RPS6KA4 | ribosomal protein S6 kinase, 90kDa, polypeptide 4 |
| RWDD3 | RWD domain containing 3 |
| SAYSD1 | SAYSVFN motif domain containing 1 |
| SEMA4D | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D |
| SGK2 | serum/glucocorticoid regulated kinase 2 |
| SIRT4 | sirtuin 4 |
| SLC22A14 | solute carrier family 22, member 14 |
| SLC35C1 | solute carrier family 35 (GDP-fucose transporter), member C1 |
| SPINK4 | serine peptidase inhibitor, Kazal type 4 |
| TFAP4 | transcription factor AP-4 (activating enhancer binding protein 4) |
| TGFBI | transforming growth factor, beta-induced, 68kDa |
| TGFBR1 | transforming growth factor, beta receptor 1 |
| TLR5 | toll-like receptor 5 |
| TM6SF1 | transmembrane 6 superfamily member 1 |
| TMEM104 | transmembrane protein 104 |
| TMOD1 | tropomodulin 1 |
| UBQLN4 | ubiquilin 4 |
| UNC119 | unc-119 homolog (C. elegans) |
| USP19 | ubiquitin specific peptidase 19 |
| VGF | VGF nerve growth factor inducible |
| VLDLR | very low density lipoprotein receptor |
| WDR76 | WD repeat domain 76 |
| XK | X-linked Kx blood group |
| XRCC2 | X-ray repair complementing defective repair in Chinese hamster cells 2 |
| ZBTB39 | zinc finger and BTB domain containing 39 |
| ZDHHC18 | zinc finger, DHHC-type containing 18 |
| ZNF428 | zinc finger protein 428 |
| ZNF551 | zinc finger protein 551 |
| ZNF639 | zinc finger protein 639 |
| ZNF747 | zinc finger protein 747 |
| ZNF862 | zinc finger protein 862 |