| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
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198 genes differentially expressed following the thiamine-7479 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ACTC1 | actin, alpha, cardiac muscle 1 |
| ADAM17 | ADAM metallopeptidase domain 17 |
| ADARB1 | adenosine deaminase, RNA-specific, B1 |
| ADD2 | adducin 2 (beta) |
| ANP32A-IT1 | ANP32A intronic transcript 1 |
| AQP3 | aquaporin 3 (Gill blood group) |
| ARAP2 | ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2 |
| ARTN | artemin |
| ATN1 | atrophin 1 |
| ATP7A | ATPase, Cu++ transporting, alpha polypeptide |
| C1QTNF9B-AS1 | C1QTNF9B antisense RNA 1 |
| CACNA1D | calcium channel, voltage-dependent, L type, alpha 1D subunit |
| CAPG | capping protein (actin filament), gelsolin-like |
| CBL | Cbl proto-oncogene, E3 ubiquitin protein ligase |
| CD53 | CD53 molecule |
| CNOT4 | CCR4-NOT transcription complex, subunit 4 |
| COPZ2 | coatomer protein complex, subunit zeta 2 |
| CRTC1 | CREB regulated transcription coactivator 1 |
| CTIF | CBP80/20-dependent translation initiation factor |
| CYP17A1 | cytochrome P450, family 17, subfamily A, polypeptide 1 |
| DPYSL4 | dihydropyrimidinase-like 4 |
| EDN1 | endothelin 1 |
| EGR1 | early growth response 1 |
| ENC1 | ectodermal-neural cortex 1 (with BTB domain) |
| ENO2 | enolase 2 (gamma, neuronal) |
| EPHA1 | EPH receptor A1 |
| EVA1B | eva-1 homolog B (C. elegans) |
| EVPL | envoplakin |
| FAAH | fatty acid amide hydrolase |
| FADS3 | fatty acid desaturase 3 |
| FAM214B | family with sequence similarity 214, member B |
| GABBR2 | gamma-aminobutyric acid (GABA) B receptor, 2 |
| GJB3 | gap junction protein, beta 3, 31kDa |
| GRM1 | glutamate receptor, metabotropic 1 |
| GRTP1 | growth hormone regulated TBC protein 1 |
| GYPB | glycophorin B (MNS blood group) |
| INHBA | inhibin, beta A |
| INPP4A | inositol polyphosphate-4-phosphatase, type I, 107kDa |
| IRF1 | interferon regulatory factor 1 |
| KCNG1 | potassium channel, voltage gated modifier subfamily G, member 1 |
| KCNQ3 | potassium channel, voltage gated KQT-like subfamily Q, member 3 |
| MAP4 | microtubule-associated protein 4 |
| MCF2L | MCF.2 cell line derived transforming sequence-like |
| MED14 | mediator complex subunit 14 |
| MED9 | mediator complex subunit 9 |
| MGEA5 | meningioma expressed antigen 5 (hyaluronidase) |
| MID1 | midline 1 |
| MPP2 | membrane protein, palmitoylated 2 (MAGUK p55 subfamily member 2) |
| MRM1 | mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae) |
| MTAP | methylthioadenosine phosphorylase |
| MYL5 | myosin, light chain 5, regulatory |
| NLE1 | notchless homolog 1 (Drosophila) |
| NME5 | NME/NM23 family member 5 |
| OPRM1 | opioid receptor, mu 1 |
| PCSK6 | proprotein convertase subtilisin/kexin type 6 |
| PDE4A | phosphodiesterase 4A, cAMP-specific |
| PICK1 | protein interacting with PRKCA 1 |
| PIN1P1 | peptidylprolyl cis/trans isomerase, NIMA-interacting 1 pseudogene 1 |
| PLXNB1 | plexin B1 |
| PORCN | porcupine homolog (Drosophila) |
| PPIL2 | peptidylprolyl isomerase (cyclophilin)-like 2 |
| PROCR | protein C receptor, endothelial |
| PSD4 | pleckstrin and Sec7 domain containing 4 |
| RAB30 | RAB30, member RAS oncogene family |
| RAB40C | RAB40C, member RAS oncogene family |
| RANBP3 | RAN binding protein 3 |
| RAPGEFL1 | Rap guanine nucleotide exchange factor (GEF)-like 1 |
| RBM19 | RNA binding motif protein 19 |
| RCAN3 | RCAN family member 3 |
| RNF31 | ring finger protein 31 |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 |
| RTEL1 | regulator of telomere elongation helicase 1 |
| SCUBE2 | signal peptide, CUB domain, EGF-like 2 |
| SDC3 | syndecan 3 |
| SEC14L5 | SEC14-like 5 (S. cerevisiae) |
| SH3BP2 | SH3-domain binding protein 2 |
| SLC17A4 | solute carrier family 17, member 4 |
| SLC20A2 | solute carrier family 20 (phosphate transporter), member 2 |
| SLC7A8 | solute carrier family 7 (amino acid transporter light chain, L system), member 8 |
| SLC8B1 | solute carrier family 8 (sodium/lithium/calcium exchanger), member B1 |
| SPINK5 | serine peptidase inhibitor, Kazal type 5 |
| STIM1 | stromal interaction molecule 1 |
| STX7 | syntaxin 7 |
| SUGP1 | SURP and G patch domain containing 1 |
| SYNGR1 | synaptogyrin 1 |
| SYNJ1 | synaptojanin 1 |
| TNFRSF25 | tumor necrosis factor receptor superfamily, member 25 |
| TP53I11 | tumor protein p53 inducible protein 11 |
| TPP1 | tripeptidyl peptidase I |
| TREX1 | three prime repair exonuclease 1 |
| TRIM29 | tripartite motif containing 29 |
| TTLL3 | tubulin tyrosine ligase-like family member 3 |
| USP22 | ubiquitin specific peptidase 22 |
| VDR | vitamin D (1,25- dihydroxyvitamin D3) receptor |
| WDR25 | WD repeat domain 25 |
| XRCC4 | X-ray repair complementing defective repair in Chinese hamster cells 4 |
| ZBTB25 | zinc finger and BTB domain containing 25 |
| ZHX3 | zinc fingers and homeoboxes 3 |
| ZNF442 | zinc finger protein 442 |
| Symbol | Name |
|---|---|
| ACADSB | acyl-CoA dehydrogenase, short/branched chain |
| AEN | apoptosis enhancing nuclease |
| ANXA2P3 | annexin A2 pseudogene 3 |
| ARFGAP1 | ADP-ribosylation factor GTPase activating protein 1 |
| BCAS1 | breast carcinoma amplified sequence 1 |
| BPGM | 2,3-bisphosphoglycerate mutase |
| C11ORF30 | chromosome 11 open reading frame 30 |
| C16ORF45 | chromosome 16 open reading frame 45 |
| C7ORF43 | chromosome 7 open reading frame 43 |
| CAMK1 | calcium/calmodulin-dependent protein kinase I |
| CD82 | CD82 molecule |
| CDC42EP1 | CDC42 effector protein (Rho GTPase binding) 1 |
| CHML | choroideremia-like (Rab escort protein 2) |
| CHST7 | carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 7 |
| CIDEC | cell death-inducing DFFA-like effector c |
| CNGB3 | cyclic nucleotide gated channel beta 3 |
| COQ3 | coenzyme Q3 methyltransferase |
| CRABP1 | cellular retinoic acid binding protein 1 |
| DCUN1D2 | DCN1, defective in cullin neddylation 1, domain containing 2 |
| DENND4A | DENN/MADD domain containing 4A |
| DGCR11 | DiGeorge syndrome critical region gene 11 (non-protein coding) |
| DGKE | diacylglycerol kinase, epsilon 64kDa |
| DMTN | dematin actin binding protein |
| DNAJA4 | DnaJ (Hsp40) homolog, subfamily A, member 4 |
| DNAJC12 | DnaJ (Hsp40) homolog, subfamily C, member 12 |
| EPHA2 | EPH receptor A2 |
| FAM160B2 | family with sequence similarity 160, member B2 |
| FMO4 | flavin containing monooxygenase 4 |
| GADD45G | growth arrest and DNA-damage-inducible, gamma |
| GAREM | GRB2 associated, regulator of MAPK1 |
| GFOD1 | glucose-fructose oxidoreductase domain containing 1 |
| GPX2 | glutathione peroxidase 2 |
| GUF1 | GUF1 GTPase homolog (S. cerevisiae) |
| HCFC2 | host cell factor C2 |
| HDAC11 | histone deacetylase 11 |
| HDAC4 | histone deacetylase 4 |
| HEY2 | hes-related family bHLH transcription factor with YRPW motif 2 |
| HIST1H4F | histone cluster 1, H4f |
| IFT22 | intraflagellar transport 22 |
| INF2 | inverted formin, FH2 and WH2 domain containing |
| JRKL | JRK-like |
| KIZ | kizuna centrosomal protein |
| MCOLN3 | mucolipin 3 |
| MFSD12 | major facilitator superfamily domain containing 12 |
| MON1B | MON1 secretory trafficking family member B |
| NHEJ1 | nonhomologous end-joining factor 1 |
| NKAIN1 | Na+/K+ transporting ATPase interacting 1 |
| NRGN | neurogranin (protein kinase C substrate, RC3) |
| NT5DC3 | 5'-nucleotidase domain containing 3 |
| OSGEPL1 | O-sialoglycoprotein endopeptidase-like 1 |
| PACS1 | phosphofurin acidic cluster sorting protein 1 |
| PGGT1B | protein geranylgeranyltransferase type I, beta subunit |
| PGR | progesterone receptor |
| PILRB | paired immunoglobin-like type 2 receptor beta |
| PLD2 | phospholipase D2 |
| PRKX | protein kinase, X-linked |
| PRRG4 | proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane) |
| PTPN6 | protein tyrosine phosphatase, non-receptor type 6 |
| PVRL3 | poliovirus receptor-related 3 |
| PYCRL | pyrroline-5-carboxylate reductase-like |
| RARS | arginyl-tRNA synthetase |
| RNF19A | ring finger protein 19A, RBR E3 ubiquitin protein ligase |
| RNF25 | ring finger protein 25 |
| SAV1 | salvador family WW domain containing protein 1 |
| SCPEP1 | serine carboxypeptidase 1 |
| SH3BGR | SH3 domain binding glutamate-rich protein |
| SLC2A8 | solute carrier family 2 (facilitated glucose transporter), member 8 |
| SLC35F5 | solute carrier family 35, member F5 |
| SMEK2 | SMEK homolog 2, suppressor of mek1 (Dictyostelium) |
| SNAPC2 | small nuclear RNA activating complex, polypeptide 2, 45kDa |
| SOWAHC | sosondowah ankyrin repeat domain family member C |
| SREK1IP1 | SREK1-interacting protein 1 |
| STAG3L4 | stromal antigen 3-like 4 (pseudogene) |
| SUV39H1 | suppressor of variegation 3-9 homolog 1 (Drosophila) |
| SUV39H2 | suppressor of variegation 3-9 homolog 2 (Drosophila) |
| TMEM110 | transmembrane protein 110 |
| TMEM120B | transmembrane protein 120B |
| TMEM209 | transmembrane protein 209 |
| TMEM62 | transmembrane protein 62 |
| TMPRSS4 | transmembrane protease, serine 4 |
| TPST1 | tyrosylprotein sulfotransferase 1 |
| TRIM45 | tripartite motif containing 45 |
| TRMT2A | tRNA methyltransferase 2 homolog A (S. cerevisiae) |
| TRMU | tRNA 5-methylaminomethyl-2-thiouridylate methyltransferase |
| ULBP2 | UL16 binding protein 2 |
| UNC93B1 | unc-93 homolog B1 (C. elegans) |
| VGF | VGF nerve growth factor inducible |
| VPS54 | vacuolar protein sorting 54 homolog (S. cerevisiae) |
| WDR44 | WD repeat domain 44 |
| ZBTB3 | zinc finger and BTB domain containing 3 |
| ZCWPW1 | zinc finger, CW type with PWWP domain 1 |
| ZFYVE16 | zinc finger, FYVE domain containing 16 |
| ZNF165 | zinc finger protein 165 |
| ZNF219 | zinc finger protein 219 |
| ZNF324 | zinc finger protein 324 |
| ZNF668 | zinc finger protein 668 |
| ZNF701 | zinc finger protein 701 |
| ZNF74 | zinc finger protein 74 |
| ZSCAN31 | zinc finger and SCAN domain containing 31 |