| Dataset | MPO Gene-Phenotype Associations |
| Category | disease or phenotype associations |
| Type | phenotype |
| Description | increased thickness of the transient structure derived from the inner cell mass which lies above the hypoblast; the epiblast tissue gives rise to the three primary germ layers (ectoderm, definitive endoderm, and mesoderm) and to the extraembryonic mesoderm of the visceral yolk sac, the allantois, and the amnion (Mammalian Phenotype Ontology, MP_0011190) |
| External Link | http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0011190 |
| Similar Terms | |
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6 gene mutations causing the thick embryonic epiblast phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.
| Symbol | Name |
|---|---|
| ACVR1 | activin A receptor, type I |
| BMPR1A | bone morphogenetic protein receptor, type IA |
| BPTF | bromodomain PHD finger transcription factor |
| ECSIT | ECSIT signalling integrator |
| PRKCI | protein kinase C, iota |
| RAC1 | ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) |
