thiethylperazine-6154 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the thiethylperazine-6154 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCA2 ATP-binding cassette, sub-family A (ABC1), member 2
ADCY1 adenylate cyclase 1 (brain)
ADCY6 adenylate cyclase 6
ADCY9 adenylate cyclase 9
ADGRG2 adhesion G protein-coupled receptor G2
AFF1 AF4/FMR2 family, member 1
AGAP2 ArfGAP with GTPase domain, ankyrin repeat and PH domain 2
AHNAK AHNAK nucleoprotein
ANGEL2 angel homolog 2 (Drosophila)
ARL2BP ADP-ribosylation factor-like 2 binding protein
ATN1 atrophin 1
ATP9B ATPase, class II, type 9B
BCR breakpoint cluster region
BMP15 bone morphogenetic protein 15
C1QTNF9B-AS1 C1QTNF9B antisense RNA 1
C2ORF27A chromosome 2 open reading frame 27A
CCNK cyclin K
CD2 CD2 molecule
CD248 CD248 molecule, endosialin
CD80 CD80 molecule
CES3 carboxylesterase 3
CHRNE cholinergic receptor, nicotinic, epsilon (muscle)
CKM creatine kinase, muscle
COL10A1 collagen, type X, alpha 1
CRH corticotropin releasing hormone
CTC1 CTS telomere maintenance complex component 1
DENND5B DENN/MADD domain containing 5B
DLGAP2 discs, large (Drosophila) homolog-associated protein 2
DTX2 deltex 2, E3 ubiquitin ligase
DYRK1A dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A
EFNA4 ephrin-A4
EPHB2 EPH receptor B2
EPN2 epsin 2
ERICH1 glutamate-rich 1
ERN2 endoplasmic reticulum to nucleus signaling 2
EXOSC2 exosome component 2
FBXO31 F-box protein 31
FGD1 FYVE, RhoGEF and PH domain containing 1
FLNC filamin C, gamma
FMO3 flavin containing monooxygenase 3
GFER growth factor, augmenter of liver regeneration
GPC1 glypican 1
GPR19 G protein-coupled receptor 19
HCFC1R1 host cell factor C1 regulator 1 (XPO1 dependent)
HGD homogentisate 1,2-dioxygenase
HIST1H2BJ histone cluster 1, H2bj
HIST1H2BM histone cluster 1, H2bm
ICA1 islet cell autoantigen 1, 69kDa
IGHG1 immunoglobulin heavy constant gamma 1 (G1m marker)
IGLV3-19 immunoglobulin lambda variable 3-19
IL16 interleukin 16
INSL5 insulin-like 5
IRF4 interferon regulatory factor 4
KCNJ2 potassium channel, inwardly rectifying subfamily J, member 2
KIF5C kinesin family member 5C
KYNU kynureninase
LINC00302 long intergenic non-protein coding RNA 302
MAP4K1 mitogen-activated protein kinase kinase kinase kinase 1
MAP7 microtubule-associated protein 7
MCAM melanoma cell adhesion molecule
MCM3AP minichromosome maintenance complex component 3 associated protein
METTL2B methyltransferase like 2B
MFGE8 milk fat globule-EGF factor 8 protein
MST1 macrophage stimulating 1
NF2 neurofibromin 2 (merlin)
NOS1 nitric oxide synthase 1 (neuronal)
NOX5 NADPH oxidase, EF-hand calcium binding domain 5
NUDT18 nudix (nucleoside diphosphate linked moiety X)-type motif 18
OGFR opioid growth factor receptor
PDE10A phosphodiesterase 10A
PDE4DIP phosphodiesterase 4D interacting protein
PELO pelota homolog (Drosophila)
PER3 period circadian clock 3
PKNOX2 PBX/knotted 1 homeobox 2
PLD2 phospholipase D2
PRKCE protein kinase C, epsilon
PYCRL pyrroline-5-carboxylate reductase-like
RASAL2 RAS protein activator like 2
RASGRP2 RAS guanyl releasing protein 2 (calcium and DAG-regulated)
RNF6 ring finger protein (C3H2C3 type) 6
RRBP1 ribosome binding protein 1
SAFB scaffold attachment factor B
SAMD4A sterile alpha motif domain containing 4A
SLAMF7 SLAM family member 7
SLCO2A1 solute carrier organic anion transporter family, member 2A1
SMAD6 SMAD family member 6
SMYD2 SET and MYND domain containing 2
SOCS7 suppressor of cytokine signaling 7
SOX4 SRY (sex determining region Y)-box 4
STARD13 StAR-related lipid transfer (START) domain containing 13
TFR2 transferrin receptor 2
TGM4 transglutaminase 4
TPMT thiopurine S-methyltransferase
TRPV1 transient receptor potential cation channel, subfamily V, member 1
TYR tyrosinase
VAV2 vav 2 guanine nucleotide exchange factor
YOD1 YOD1 deubiquitinase
ZNF185 zinc finger protein 185 (LIM domain)
ZNF235 zinc finger protein 235
ZNF446 zinc finger protein 446

decreased expression

Symbol Name
ADGRE1 adhesion G protein-coupled receptor E1
AEN apoptosis enhancing nuclease
APOBEC1 apolipoprotein B mRNA editing enzyme, catalytic polypeptide 1
ATP8B2 ATPase, aminophospholipid transporter, class I, type 8B, member 2
BBC3 BCL2 binding component 3
C11ORF63 chromosome 11 open reading frame 63
C7ORF69 chromosome 7 open reading frame 69
CBX7 chromobox homolog 7
CCDC134 coiled-coil domain containing 134
CDKL3 cyclin-dependent kinase-like 3
CELP carboxyl ester lipase pseudogene
CHRNA6 cholinergic receptor, nicotinic, alpha 6 (neuronal)
CRMP1 collapsin response mediator protein 1
CRY2 cryptochrome circadian clock 2
CTRL chymotrypsin-like
CYB5R2 cytochrome b5 reductase 2
DHRS3 dehydrogenase/reductase (SDR family) member 3
DLST dihydrolipoamide S-succinyltransferase (E2 component of 2-oxo-glutarate complex)
DUSP8 dual specificity phosphatase 8
EEF2KMT eukaryotic elongation factor 2 lysine methyltransferase
ELSPBP1 epididymal sperm binding protein 1
ERCC4 excision repair cross-complementation group 4
EYA3 EYA transcriptional coactivator and phosphatase 3
FAM127B family with sequence similarity 127, member B
FOXRED2 FAD-dependent oxidoreductase domain containing 2
FRS3 fibroblast growth factor receptor substrate 3
GAA glucosidase, alpha; acid
GABRR2 gamma-aminobutyric acid (GABA) A receptor, rho 2
GDPD3 glycerophosphodiester phosphodiesterase domain containing 3
GNG4 guanine nucleotide binding protein (G protein), gamma 4
GPR21 G protein-coupled receptor 21
GPX2 glutathione peroxidase 2
GTF2A1 general transcription factor IIA, 1, 19/37kDa
HAAO 3-hydroxyanthranilate 3,4-dioxygenase
HDAC7 histone deacetylase 7
HIST1H2AE histone cluster 1, H2ae
HTR1B 5-hydroxytryptamine (serotonin) receptor 1B, G protein-coupled
IFNA14 interferon, alpha 14
IFNA17 interferon, alpha 17
IGLV1-44 immunoglobulin lambda variable 1-44
IKZF5 IKAROS family zinc finger 5 (Pegasus)
IL12B interleukin 12B
IL12RB1 interleukin 12 receptor, beta 1
INCENP inner centromere protein antigens 135/155kDa
KLF3 Kruppel-like factor 3 (basic)
LGALS4 lectin, galactoside-binding, soluble, 4
LOC390998 ribosomal protein L10 pseudogene
LOC730101 uncharacterized LOC730101
LTC4S leukotriene C4 synthase
MAK male germ cell-associated kinase
MAP6D1 MAP6 domain containing 1
MED9 mediator complex subunit 9
METRN meteorin, glial cell differentiation regulator
METTL16 methyltransferase like 16
MOCOS molybdenum cofactor sulfurase
MRAS muscle RAS oncogene homolog
MVD mevalonate (diphospho) decarboxylase
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding)
NKX3-2 NK3 homeobox 2
OR1G1 olfactory receptor, family 1, subfamily G, member 1
P2RX5 purinergic receptor P2X, ligand gated ion channel, 5
P2RY11 purinergic receptor P2Y, G-protein coupled, 11
PAFAH1B2 platelet-activating factor acetylhydrolase 1b, catalytic subunit 2 (30kDa)
PDPR pyruvate dehydrogenase phosphatase regulatory subunit
PGBD5 piggyBac transposable element derived 5
PIPOX pipecolic acid oxidase
PRKCZ protein kinase C, zeta
PROL1 proline rich, lacrimal 1
QTRT1 queuine tRNA-ribosyltransferase 1
RAB33A RAB33A, member RAS oncogene family
RABL3 RAB, member of RAS oncogene family-like 3
RAC3 ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3)
RASAL1 RAS protein activator like 1 (GAP1 like)
RNF126P1 ring finger protein 126 pseudogene 1
RNF25 ring finger protein 25
RNPEPL1 arginyl aminopeptidase (aminopeptidase B)-like 1
RPUSD2 RNA pseudouridylate synthase domain containing 2
RSPH14 radial spoke head 14 homolog (Chlamydomonas)
SGPP1 sphingosine-1-phosphate phosphatase 1
SLC22A14 solute carrier family 22, member 14
SLC22A4 solute carrier family 22 (organic cation/zwitterion transporter), member 4
SLC2A9 solute carrier family 2 (facilitated glucose transporter), member 9
SMUG1 single-strand-selective monofunctional uracil-DNA glycosylase 1
STEAP1 six transmembrane epithelial antigen of the prostate 1
TCTN1 tectonic family member 1
TEX40 testis expressed 40
TGFBR1 transforming growth factor, beta receptor 1
TIMP2 TIMP metallopeptidase inhibitor 2
TRAF1 TNF receptor-associated factor 1
TRIM25 tripartite motif containing 25
UNC119 unc-119 homolog (C. elegans)
USP5 ubiquitin specific peptidase 5 (isopeptidase T)
WDR91 WD repeat domain 91
ZIC3 Zic family member 3
ZMAT3 zinc finger, matrin-type 3
ZNF276 zinc finger protein 276
ZNF480 zinc finger protein 480
ZNF862 zinc finger protein 862