thin myocardium Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description reduced thickness of the cardiac muscle layer (Mammalian Phenotype Ontology, MP_0002652)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0002652
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Genes

71 gene mutations causing the thin myocardium phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
ADGRG6 adhesion G protein-coupled receptor G6
ADRBK1 adrenergic, beta, receptor kinase 1
AKAP13 A kinase (PRKA) anchor protein 13
ANKRD17 ankyrin repeat domain 17
ATE1 arginyltransferase 1
B9D1 B9 protein domain 1
BCAR1 breast cancer anti-estrogen resistance 1
CASP8 caspase 8, apoptosis-related cysteine peptidase
CFLAR CASP8 and FADD-like apoptosis regulator
CHD7 chromodomain helicase DNA binding protein 7
CXADR coxsackie virus and adenovirus receptor
DES desmin
DNM1L dynamin 1-like
ENG endoglin
EP300 E1A binding protein p300
FADD Fas (TNFRSF6)-associated via death domain
FGFR1 fibroblast growth factor receptor 1
FGFRL1 fibroblast growth factor receptor-like 1
FOXC2 forkhead box C2
FOXM1 forkhead box M1
GATA4 GATA binding protein 4
GBE1 glucan (1,4-alpha-), branching enzyme 1
GJC1 gap junction protein, gamma 1, 45kDa
HAND2 heart and neural crest derivatives expressed 2
HBEGF heparin-binding EGF-like growth factor
HOPX HOP homeobox
ITGAV integrin, alpha V
JARID2 jumonji, AT rich interactive domain 2
JUP junction plakoglobin
KRAS Kirsten rat sarcoma viral oncogene homolog
LMNA lamin A/C
MAPK1 mitogen-activated protein kinase 1
MAPK14 mitogen-activated protein kinase 14
MAPK7 mitogen-activated protein kinase 7
MB myoglobin
MED1 mediator complex subunit 1
MEOX2 mesenchyme homeobox 2
MGRN1 mahogunin ring finger 1, E3 ubiquitin protein ligase
MKL2 MKL/myocardin-like 2
MYCN v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog
NACA nascent polypeptide-associated complex alpha subunit
NCOA6 nuclear receptor coactivator 6
NGF nerve growth factor (beta polypeptide)
PAK4 p21 protein (Cdc42/Rac)-activated kinase 4
PDCD10 programmed cell death 10
PDPN podoplanin
PKD1 polycystic kidney disease 1 (autosomal dominant)
PPARG peroxisome proliferator-activated receptor gamma
PRDM6 PR domain containing 6
PTPN11 protein tyrosine phosphatase, non-receptor type 11
PTPRJ protein tyrosine phosphatase, receptor type, J
RB1CC1 RB1-inducible coiled-coil 1
RBL2 retinoblastoma-like 2
SALL4 spalt-like transcription factor 4
SENP2 SUMO1/sentrin/SMT3 specific peptidase 2
SHC1 SHC (Src homology 2 domain containing) transforming protein 1
SRSF10 serine/arginine-rich splicing factor 10
TAB1 TGF-beta activated kinase 1/MAP3K7 binding protein 1
TCF21 transcription factor 21
TDG thymine-DNA glycosylase
TGFBR3 transforming growth factor, beta receptor III
TMEM100 transmembrane protein 100
TMOD1 tropomodulin 1
TMSB4X thymosin beta 4, X-linked
TTN titin
UBP1 upstream binding protein 1 (LBP-1a)
UTF1 undifferentiated embryonic cell transcription factor 1
VCAM1 vascular cell adhesion molecule 1
VCL vinculin
WNK1 WNK lysine deficient protein kinase 1
ZFPM2 zinc finger protein, FOG family member 2