thiocolchicoside-1726 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the thiocolchicoside-1726 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACAN aggrecan
ADAM20 ADAM metallopeptidase domain 20
AGRP agouti related neuropeptide
ARNTL aryl hydrocarbon receptor nuclear translocator-like
ATP5SL ATP5S-like
ATXN2 ataxin 2
BAD BCL2-associated agonist of cell death
BAZ2A bromodomain adjacent to zinc finger domain, 2A
BIN1 bridging integrator 1
BRD1 bromodomain containing 1
CARHSP1 calcium regulated heat stable protein 1, 24kDa
CCZ1 CCZ1 vacuolar protein trafficking and biogenesis associated homolog (S. cerevisiae)
CD177 CD177 molecule
CD2BP2 CD2 (cytoplasmic tail) binding protein 2
CEP70 centrosomal protein 70kDa
CHST2 carbohydrate (N-acetylglucosamine-6-O) sulfotransferase 2
CYB561 cytochrome b561
DDAH2 dimethylarginine dimethylaminohydrolase 2
DNAL4 dynein, axonemal, light chain 4
DPH2 DPH2 homolog (S. cerevisiae)
DYRK2 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2
EHD1 EH-domain containing 1
EIF2AK2 eukaryotic translation initiation factor 2-alpha kinase 2
EPHB2 EPH receptor B2
EPS8L1 EPS8-like 1
FAM107A family with sequence similarity 107, member A
FANCA Fanconi anemia, complementation group A
FASTK Fas-activated serine/threonine kinase
FBLN1 fibulin 1
FBXO31 F-box protein 31
FCHSD2 FCH and double SH3 domains 2
FLOT1 flotillin 1
FRMD8 FERM domain containing 8
GGA2 golgi-associated, gamma adaptin ear containing, ARF binding protein 2
GIT1 G protein-coupled receptor kinase interacting ArfGAP 1
GOLGA2 golgin A2
HCFC1 host cell factor C1
HDAC5 histone deacetylase 5
HFE hemochromatosis
HTT huntingtin
IDS iduronate 2-sulfatase
ING4 inhibitor of growth family, member 4
ITGA2B integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41)
KAT6B K(lysine) acetyltransferase 6B
KCNQ1 potassium channel, voltage gated KQT-like subfamily Q, member 1
KIAA1109 KIAA1109
KLF6 Kruppel-like factor 6
LILRB3 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3
MED21 mediator complex subunit 21
METTL13 methyltransferase like 13
MSH3 mutS homolog 3
MTERF4 mitochondrial transcription termination factor 4
MTHFR methylenetetrahydrofolate reductase (NAD(P)H)
MXRA8 matrix-remodelling associated 8
NEDD8 neural precursor cell expressed, developmentally down-regulated 8
NFX1 nuclear transcription factor, X-box binding 1
OGFR opioid growth factor receptor
OPA1 optic atrophy 1 (autosomal dominant)
ORC4 origin recognition complex, subunit 4
OSGIN2 oxidative stress induced growth inhibitor family member 2
PAFAH1B3 platelet-activating factor acetylhydrolase 1b, catalytic subunit 3 (29kDa)
PAK1IP1 PAK1 interacting protein 1
PARD3 par-3 family cell polarity regulator
PCSK6 proprotein convertase subtilisin/kexin type 6
PIGV phosphatidylinositol glycan anchor biosynthesis, class V
PIM2 Pim-2 proto-oncogene, serine/threonine kinase
PLEC plectin
PLEKHG3 pleckstrin homology domain containing, family G (with RhoGef domain) member 3
PPP1R16B protein phosphatase 1, regulatory subunit 16B
PVT1 Pvt1 oncogene (non-protein coding)
QPCT glutaminyl-peptide cyclotransferase
RECQL4 RecQ protein-like 4
RGS3 regulator of G-protein signaling 3
RHOT2 ras homolog family member T2
RITA1 RBPJ interacting and tubulin associated 1
RPS4Y1 ribosomal protein S4, Y-linked 1
SAP30 Sin3A-associated protein, 30kDa
SCML1 sex comb on midleg-like 1 (Drosophila)
SEC31B SEC31 homolog B (S. cerevisiae)
SH2D2A SH2 domain containing 2A
SHC1 SHC (Src homology 2 domain containing) transforming protein 1
SIDT2 SID1 transmembrane family, member 2
SLCO4A1 solute carrier organic anion transporter family, member 4A1
SMPD2 sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase)
SND1-IT1 SND1 intronic transcript 1
SP140L SP140 nuclear body protein-like
SPR sepiapterin reductase (7,8-dihydrobiopterin:NADP+ oxidoreductase)
TBC1D30 TBC1 domain family, member 30
TBXA2R thromboxane A2 receptor
TCL1A T-cell leukemia/lymphoma 1A
TLE1 transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)
TNFRSF21 tumor necrosis factor receptor superfamily, member 21
TRAPPC12 trafficking protein particle complex 12
TSFM Ts translation elongation factor, mitochondrial
UBL3 ubiquitin-like 3
USP20 ubiquitin specific peptidase 20
ZFYVE9 zinc finger, FYVE domain containing 9
ZMYND8 zinc finger, MYND-type containing 8
ZNF518A zinc finger protein 518A

decreased expression

Symbol Name
ABCC4 ATP-binding cassette, sub-family C (CFTR/MRP), member 4
ACADVL acyl-CoA dehydrogenase, very long chain
ACSL4 acyl-CoA synthetase long-chain family member 4
ACSL5 acyl-CoA synthetase long-chain family member 5
AIM2 absent in melanoma 2
ATAD2B ATPase family, AAA domain containing 2B
ATP8B1 ATPase, aminophospholipid transporter, class I, type 8B, member 1
BCL7C B-cell CLL/lymphoma 7C
BMS1 BMS1 ribosome biogenesis factor
BRD9 bromodomain containing 9
CASD1 CAS1 domain containing 1
CCZ1B CCZ1 vacuolar protein trafficking and biogenesis associated homolog B (S. cerevisiae)
CHMP1A charged multivesicular body protein 1A
CLCN6 chloride channel, voltage-sensitive 6
DBR1 debranching RNA lariats 1
DDX54 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54
DNAJB6 DnaJ (Hsp40) homolog, subfamily B, member 6
DNASE1L1 deoxyribonuclease I-like 1
DRD5 dopamine receptor D5
EDAR ectodysplasin A receptor
ELSPBP1 epididymal sperm binding protein 1
EPX eosinophil peroxidase
ERCC6 excision repair cross-complementation group 6
FADS2 fatty acid desaturase 2
FAM188A family with sequence similarity 188, member A
FAM46A family with sequence similarity 46, member A
FKBP2 FK506 binding protein 2, 13kDa
FOXK2 forkhead box K2
GATC glutamyl-tRNA(Gln) amidotransferase, subunit C
GLOD4 glyoxalase domain containing 4
GNAZ guanine nucleotide binding protein (G protein), alpha z polypeptide
GSTA4 glutathione S-transferase alpha 4
GTF2F2 general transcription factor IIF, polypeptide 2, 30kDa
GTF2H3 general transcription factor IIH, polypeptide 3, 34kDa
HERC5 HECT and RLD domain containing E3 ubiquitin protein ligase 5
HIRIP3 HIRA interacting protein 3
HMOX2 heme oxygenase 2
ITPKC inositol-trisphosphate 3-kinase C
KCTD3 potassium channel tetramerization domain containing 3
KDM5C lysine (K)-specific demethylase 5C
KIF3B kinesin family member 3B
KIFAP3 kinesin-associated protein 3
KIFC1 kinesin family member C1
LAX1 lymphocyte transmembrane adaptor 1
LOC390998 ribosomal protein L10 pseudogene
LRRK1 leucine-rich repeat kinase 1
LXN latexin
MAN2C1 mannosidase, alpha, class 2C, member 1
MCM9 minichromosome maintenance complex component 9
MEAF6 MYST/Esa1-associated factor 6
MED23 mediator complex subunit 23
MLYCD malonyl-CoA decarboxylase
MRPL2 mitochondrial ribosomal protein L2
MSL2 male-specific lethal 2 homolog (Drosophila)
MT1HL1 metallothionein 1H-like 1
NACAP1 nascent-polypeptide-associated complex alpha polypeptide pseudogene 1
NEDD4 neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase
NFS1 NFS1 cysteine desulfurase
NKG7 natural killer cell granule protein 7
PAQR3 progestin and adipoQ receptor family member III
PARM1 prostate androgen-regulated mucin-like protein 1
PEX26 peroxisomal biogenesis factor 26
PLIN3 perilipin 3
PPP1R14D protein phosphatase 1, regulatory (inhibitor) subunit 14D
PRCC papillary renal cell carcinoma (translocation-associated)
PSKH1 protein serine kinase H1
PTBP2 polypyrimidine tract binding protein 2
RAB3IL1 RAB3A interacting protein (rabin3)-like 1
RFPL3 ret finger protein-like 3
RSL24D1 ribosomal L24 domain containing 1
RTFDC1 replication termination factor 2 domain containing 1
SARS2 seryl-tRNA synthetase 2, mitochondrial
SETD1B SET domain containing 1B
SHPK sedoheptulokinase
SKA1 spindle and kinetochore associated complex subunit 1
SLC19A2 solute carrier family 19 (thiamine transporter), member 2
SLC22A18AS solute carrier family 22 (organic cation transporter), member 18 antisense
SLC9A8 solute carrier family 9, subfamily A (NHE8, cation proton antiporter 8), member 8
SNX15 sorting nexin 15
SPRY1 sprouty homolog 1, antagonist of FGF signaling (Drosophila)
STK39 serine threonine kinase 39
SUV39H1 suppressor of variegation 3-9 homolog 1 (Drosophila)
TEFM transcription elongation factor, mitochondrial
TMEM14A transmembrane protein 14A
TMEM246 transmembrane protein 246
TRANK1 tetratricopeptide repeat and ankyrin repeat containing 1
TRIM9 tripartite motif containing 9
TSR2 TSR2, 20S rRNA accumulation, homolog (S. cerevisiae)
TUBA3C tubulin, alpha 3c
TUBA4B tubulin, alpha 4b
TYW1 tRNA-yW synthesizing protein 1 homolog (S. cerevisiae)
UPF2 UPF2 regulator of nonsense transcripts homolog (yeast)
URGCP upregulator of cell proliferation
XPC xeroderma pigmentosum, complementation group C
ZNF223 zinc finger protein 223
ZNF273 zinc finger protein 273
ZNF350 zinc finger protein 350
ZNF426 zinc finger protein 426
ZNF721 zinc finger protein 721