thiocolchicoside-2875 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

199 genes differentially expressed following the thiocolchicoside-2875 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCD1 ATP-binding cassette, sub-family D (ALD), member 1
ADAM2 ADAM metallopeptidase domain 2
ADGRA2 adhesion G protein-coupled receptor A2
AGFG1 ArfGAP with FG repeats 1
ARC activity-regulated cytoskeleton-associated protein
ARID4B AT rich interactive domain 4B (RBP1-like)
ATN1 atrophin 1
ATP2B2 ATPase, Ca++ transporting, plasma membrane 2
BAZ2B bromodomain adjacent to zinc finger domain, 2B
C3ORF18 chromosome 3 open reading frame 18
CACNA1G calcium channel, voltage-dependent, T type, alpha 1G subunit
CALML5 calmodulin-like 5
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase
CD244 CD244 molecule, natural killer cell receptor 2B4
CDC42BPA CDC42 binding protein kinase alpha (DMPK-like)
CDK19 cyclin-dependent kinase 19
CFAP45 cilia and flagella associated protein 45
CHRNB2 cholinergic receptor, nicotinic, beta 2 (neuronal)
CIDEB cell death-inducing DFFA-like effector b
CNTNAP2 contactin associated protein-like 2
COMT catechol-O-methyltransferase
CYLD cylindromatosis (turban tumor syndrome)
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
DLX2 distal-less homeobox 2
DMBT1 deleted in malignant brain tumors 1
DYNC1LI2 dynein, cytoplasmic 1, light intermediate chain 2
EGFL7 EGF-like-domain, multiple 7
EPM2A epilepsy, progressive myoclonus type 2A, Lafora disease (laforin)
EXOSC1 exosome component 1
FKRP fukutin related protein
FOXG1 forkhead box G1
GP1BB glycoprotein Ib (platelet), beta polypeptide
GPER1 G protein-coupled estrogen receptor 1
HOXA6 homeobox A6
HOXA9 homeobox A9
HR hair growth associated
HSPG2 heparan sulfate proteoglycan 2
IFI6 interferon, alpha-inducible protein 6
IL1RN interleukin 1 receptor antagonist
IQSEC2 IQ motif and Sec7 domain 2
IRS2 insulin receptor substrate 2
JAG1 jagged 1
KANK1 KN motif and ankyrin repeat domains 1
KCNA6 potassium channel, voltage gated shaker related subfamily A, member 6
KCTD17 potassium channel tetramerization domain containing 17
KMT2A lysine (K)-specific methyltransferase 2A
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MCF2L MCF.2 cell line derived transforming sequence-like
MMP25 matrix metallopeptidase 25
MUC5B mucin 5B, oligomeric mucus/gel-forming
MX1 MX dynamin-like GTPase 1
MYO9B myosin IXB
N4BP2L2-IT2 N4BPL2 intronic transcript 2
NFATC1 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1
NPY4R neuropeptide Y receptor Y4
NR4A1 nuclear receptor subfamily 4, group A, member 1
OCM2 oncomodulin 2
OSBPL10 oxysterol binding protein-like 10
OXCT2 3-oxoacid CoA transferase 2
PCNX pecanex homolog (Drosophila)
PCNXL2 pecanex-like 2 (Drosophila)
PER1 period circadian clock 1
PHOX2A paired-like homeobox 2a
PIP5K1A phosphatidylinositol-4-phosphate 5-kinase, type I, alpha
PLAC4 placenta-specific 4
PLAGL1 pleiomorphic adenoma gene-like 1
PLK3 polo-like kinase 3
PLLP plasmolipin
PML promyelocytic leukemia
PON3 paraoxonase 3
RAB3IL1 RAB3A interacting protein (rabin3)-like 1
RABEP2 rabaptin, RAB GTPase binding effector protein 2
RGL1 ral guanine nucleotide dissociation stimulator-like 1
RGS2 regulator of G-protein signaling 2
RIF1 replication timing regulatory factor 1
RND1 Rho family GTPase 1
SDC2 syndecan 2
SH2D2A SH2 domain containing 2A
SLC47A1 solute carrier family 47 (multidrug and toxin extrusion), member 1
SMG5 SMG5 nonsense mediated mRNA decay factor
SPDEF SAM pointed domain containing ETS transcription factor
SPOCK2 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2
SPTB spectrin, beta, erythrocytic
SSPN sarcospan
TAOK2 TAO kinase 2
TBC1D2 TBC1 domain family, member 2
TGFB2 transforming growth factor, beta 2
THRB thyroid hormone receptor, beta
TIMP3 TIMP metallopeptidase inhibitor 3
TPSG1 tryptase gamma 1
TSPAN9 tetraspanin 9
TTLL5 tubulin tyrosine ligase-like family member 5
WDTC1 WD and tetratricopeptide repeats 1
XRCC4 X-ray repair complementing defective repair in Chinese hamster cells 4
ZBTB17 zinc finger and BTB domain containing 17
ZNF286A zinc finger protein 286A
ZNF446 zinc finger protein 446
ZNF528 zinc finger protein 528
ZZEF1 zinc finger, ZZ-type with EF-hand domain 1

decreased expression

Symbol Name
ACTG2 actin, gamma 2, smooth muscle, enteric
AGMAT agmatine ureohydrolase (agmatinase)
ARHGEF1 Rho guanine nucleotide exchange factor (GEF) 1
ARSB arylsulfatase B
BCAS1 breast carcinoma amplified sequence 1
BGLAP bone gamma-carboxyglutamate (gla) protein
BRAF B-Raf proto-oncogene, serine/threonine kinase
BTF3P12 basic transcription factor 3 pseudogene 12
C3 complement component 3
CAMK4 calcium/calmodulin-dependent protein kinase IV
CCDC121 coiled-coil domain containing 121
CDK3 cyclin-dependent kinase 3
CEP85 centrosomal protein 85kDa
CHM choroideremia (Rab escort protein 1)
CHML choroideremia-like (Rab escort protein 2)
CTNNBIP1 catenin, beta interacting protein 1
DAPP1 dual adaptor of phosphotyrosine and 3-phosphoinositides
DGAT1 diacylglycerol O-acyltransferase 1
DMTN dematin actin binding protein
DNAJC3 DnaJ (Hsp40) homolog, subfamily C, member 3
DNALI1 dynein, axonemal, light intermediate chain 1
DYSF dysferlin
EFNA3 ephrin-A3
EIF2S3 eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa
ERN1 endoplasmic reticulum to nucleus signaling 1
ETAA1 Ewing tumor-associated antigen 1
F3 coagulation factor III (thromboplastin, tissue factor)
FAM188A family with sequence similarity 188, member A
FLCN folliculin
FLT4 fms-related tyrosine kinase 4
FZD4 frizzled class receptor 4
GNA13 guanine nucleotide binding protein (G protein), alpha 13
GPRIN2 G protein regulated inducer of neurite outgrowth 2
GSTM1 glutathione S-transferase mu 1
GUSBP3 glucuronidase, beta pseudogene 3
HLA-J major histocompatibility complex, class I, J (pseudogene)
HSD17B11 hydroxysteroid (17-beta) dehydrogenase 11
IGFBP6 insulin-like growth factor binding protein 6
IRF2BP1 interferon regulatory factor 2 binding protein 1
KCNS3 potassium voltage-gated channel, modifier subfamily S, member 3
LIN7B lin-7 homolog B (C. elegans)
LMBR1L limb development membrane protein 1-like
LPPR1 lipid phosphate phosphatase-related protein type 1
LY6D lymphocyte antigen 6 complex, locus D
LYL1 lymphoblastic leukemia associated hematopoiesis regulator 1
LYPD3 LY6/PLAUR domain containing 3
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B
MBTD1 mbt domain containing 1
MED18 mediator complex subunit 18
METTL16 methyltransferase like 16
MUL1 mitochondrial E3 ubiquitin protein ligase 1
NLRX1 NLR family member X1
PARD6B par-6 family cell polarity regulator beta
PARG poly (ADP-ribose) glycohydrolase
PDE12 phosphodiesterase 12
PDK1 pyruvate dehydrogenase kinase, isozyme 1
PIGN phosphatidylinositol glycan anchor biosynthesis, class N
PLA2G15 phospholipase A2, group XV
PLA2G3 phospholipase A2, group III
PNPLA6 patatin-like phospholipase domain containing 6
POLR3D polymerase (RNA) III (DNA directed) polypeptide D, 44kDa
PRR4 proline rich 4 (lacrimal)
PRRG2 proline rich Gla (G-carboxyglutamic acid) 2
RAB30 RAB30, member RAS oncogene family
RCBTB2 regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2
RECQL4 RecQ protein-like 4
RHPN1-AS1 RHPN1 antisense RNA 1 (head to head)
RNASEL ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent)
RNF19A ring finger protein 19A, RBR E3 ubiquitin protein ligase
RNF2 ring finger protein 2
RWDD3 RWD domain containing 3
SCAI suppressor of cancer cell invasion
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
SGTA small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha
SLC16A10 solute carrier family 16 (aromatic amino acid transporter), member 10
SLC35F6 solute carrier family 35, member F6
SNAPC2 small nuclear RNA activating complex, polypeptide 2, 45kDa
SOX3 SRY (sex determining region Y)-box 3
TAF13 TAF13 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 18kDa
TNFSF9 tumor necrosis factor (ligand) superfamily, member 9
TNS2 tensin 2
TRIM5 tripartite motif containing 5
TTC33 tetratricopeptide repeat domain 33
TTLL1 tubulin tyrosine ligase-like family member 1
TUT1 terminal uridylyl transferase 1, U6 snRNA-specific
TYRP1 tyrosinase-related protein 1
USP6NL USP6 N-terminal like
WDR76 WD repeat domain 76
XRCC2 X-ray repair complementing defective repair in Chinese hamster cells 2
YY2 YY2 transcription factor
ZC3H3 zinc finger CCCH-type containing 3
ZDHHC14 zinc finger, DHHC-type containing 14
ZFAND3 zinc finger, AN1-type domain 3
ZFHX2 zinc finger homeobox 2
ZNF16 zinc finger protein 16
ZNF329 zinc finger protein 329
ZNF365 zinc finger protein 365
ZNF442 zinc finger protein 442
ZNF551 zinc finger protein 551