thiocolchicoside-5095 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

194 genes differentially expressed following the thiocolchicoside-5095 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ALOX5AP arachidonate 5-lipoxygenase-activating protein
AOC2 amine oxidase, copper containing 2 (retina-specific)
APBB2 amyloid beta (A4) precursor protein-binding, family B, member 2
APOB apolipoprotein B
APOC1 apolipoprotein C-I
ASCL1 achaete-scute family bHLH transcription factor 1
BATF basic leucine zipper transcription factor, ATF-like
BMP4 bone morphogenetic protein 4
C11ORF63 chromosome 11 open reading frame 63
C22ORF24 chromosome 22 open reading frame 24
CACNG1 calcium channel, voltage-dependent, gamma subunit 1
CALCR calcitonin receptor
CASP10 caspase 10, apoptosis-related cysteine peptidase
CCDC40 coiled-coil domain containing 40
CD28 CD28 molecule
CDHR2 cadherin-related family member 2
CEP68 centrosomal protein 68kDa
CLCN5 chloride channel, voltage-sensitive 5
CLTC clathrin, heavy chain (Hc)
CLUHP3 clustered mitochondria (cluA/CLU1) homolog pseudogene 3
CPEB1 cytoplasmic polyadenylation element binding protein 1
CRTC1 CREB regulated transcription coactivator 1
DGKA diacylglycerol kinase, alpha 80kDa
DNM2 dynamin 2
DOK3 docking protein 3
DOK5 docking protein 5
DRP2 dystrophin related protein 2
EGR1 early growth response 1
ELK4 ELK4, ETS-domain protein (SRF accessory protein 1)
ERN2 endoplasmic reticulum to nucleus signaling 2
ETV3 ets variant 3
FAM120C family with sequence similarity 120C
FOXO4 forkhead box O4
GABRR2 gamma-aminobutyric acid (GABA) A receptor, rho 2
HDAC11 histone deacetylase 11
HRASLS2 HRAS-like suppressor 2
HUS1 HUS1 checkpoint homolog (S. pombe)
IL2RG interleukin 2 receptor, gamma
ITGA7 integrin, alpha 7
KCNS1 potassium voltage-gated channel, modifier subfamily S, member 1
LMX1B LIM homeobox transcription factor 1, beta
LPCAT4 lysophosphatidylcholine acyltransferase 4
MAGEA5 melanoma antigen family A5
MCOLN3 mucolipin 3
MEFV Mediterranean fever
METTL7A methyltransferase like 7A
MYOZ1 myozenin 1
NAGLU N-acetylglucosaminidase, alpha
NCAPH2 non-SMC condensin II complex, subunit H2
NEUROD6 neuronal differentiation 6
NOX1 NADPH oxidase 1
NPIPB3 nuclear pore complex interacting protein family, member B3
PAQR5 progestin and adipoQ receptor family member V
PAX8 paired box 8
PCDHA5 protocadherin alpha 5
PDE8B phosphodiesterase 8B
PDGFRA platelet-derived growth factor receptor, alpha polypeptide
PECAM1 platelet/endothelial cell adhesion molecule 1
PLA2G5 phospholipase A2, group V
PLCL2 phospholipase C-like 2
PLEKHF1 pleckstrin homology domain containing, family F (with FYVE domain) member 1
PPIL2 peptidylprolyl isomerase (cyclophilin)-like 2
PPP4R4 protein phosphatase 4, regulatory subunit 4
PRDX2 peroxiredoxin 2
PTGER3 prostaglandin E receptor 3 (subtype EP3)
PTPRJ protein tyrosine phosphatase, receptor type, J
RAD51 RAD51 recombinase
RIBC2 RIB43A domain with coiled-coils 2
RUNX1 runt-related transcription factor 1
RUNX3 runt-related transcription factor 3
SAA3P serum amyloid A3 pseudogene
SARS2 seryl-tRNA synthetase 2, mitochondrial
SBNO1 strawberry notch homolog 1 (Drosophila)
SETD8 SET domain containing (lysine methyltransferase) 8
SFTPB surfactant protein B
SH2D2A SH2 domain containing 2A
SIGLEC8 sialic acid binding Ig-like lectin 8
SIRT5 sirtuin 5
SLC39A9 solute carrier family 39, member 9
SLC8A2 solute carrier family 8 (sodium/calcium exchanger), member 2
SORBS1 sorbin and SH3 domain containing 1
SP100 SP100 nuclear antigen
SPATA1 spermatogenesis associated 1
SRCAP Snf2-related CREBBP activator protein
TEF thyrotrophic embryonic factor
TGFB1 transforming growth factor, beta 1
TK2 thymidine kinase 2, mitochondrial
TMEM231 transmembrane protein 231
TPM3 tropomyosin 3
TRO trophinin
TSPAN7 tetraspanin 7
VIPR2 vasoactive intestinal peptide receptor 2
WHSC1L1 Wolf-Hirschhorn syndrome candidate 1-like 1
XRCC6 X-ray repair complementing defective repair in Chinese hamster cells 6
ZC3H7B zinc finger CCCH-type containing 7B
ZNF34 zinc finger protein 34
ZNF688 zinc finger protein 688

decreased expression

Symbol Name
AAAS achalasia, adrenocortical insufficiency, alacrimia
ABCA3 ATP-binding cassette, sub-family A (ABC1), member 3
ABHD8 abhydrolase domain containing 8
AK5 adenylate kinase 5
APOL6 apolipoprotein L, 6
ARHGAP5 Rho GTPase activating protein 5
ARHGEF28 Rho guanine nucleotide exchange factor (GEF) 28
ARID3B AT rich interactive domain 3B (BRIGHT-like)
ASPSCR1 alveolar soft part sarcoma chromosome region, candidate 1
ATAD5 ATPase family, AAA domain containing 5
BAG4 BCL2-associated athanogene 4
BAHCC1 BAH domain and coiled-coil containing 1
BEX1 brain expressed, X-linked 1
BHLHB9 basic helix-loop-helix domain containing, class B, 9
C16ORF59 chromosome 16 open reading frame 59
C1R complement component 1, r subcomponent
CCDC85C coiled-coil domain containing 85C
CDK6 cyclin-dependent kinase 6
CNTNAP1 contactin associated protein 1
CSGALNACT2 chondroitin sulfate N-acetylgalactosaminyltransferase 2
CXCL2 chemokine (C-X-C motif) ligand 2
CXORF56 chromosome X open reading frame 56
DBR1 debranching RNA lariats 1
DCAF13 DDB1 and CUL4 associated factor 13
DENND4A DENN/MADD domain containing 4A
DNMBP dynamin binding protein
DYNC1I1 dynein, cytoplasmic 1, intermediate chain 1
ERF Ets2 repressor factor
EYA4 EYA transcriptional coactivator and phosphatase 4
FAM222B family with sequence similarity 222, member B
FBXL15 F-box and leucine-rich repeat protein 15
FGD1 FYVE, RhoGEF and PH domain containing 1
FKBP5 FK506 binding protein 5
GLTP glycolipid transfer protein
GNB1L guanine nucleotide binding protein (G protein), beta polypeptide 1-like
GPATCH1 G patch domain containing 1
GRWD1 glutamate-rich WD repeat containing 1
GTF2A1 general transcription factor IIA, 1, 19/37kDa
HIRA histone cell cycle regulator
HIST1H1D histone cluster 1, H1d
HIST1H2AJ histone cluster 1, H2aj
HIST1H2AM histone cluster 1, H2am
HIVEP1 human immunodeficiency virus type I enhancer binding protein 1
HLX H2.0-like homeobox
ICK intestinal cell (MAK-like) kinase
IFI6 interferon, alpha-inducible protein 6
IFT54 intraflagellar transport 54
JUNB jun B proto-oncogene
KCNN1 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 1
KIAA1551 KIAA1551
KIRREL kin of IRRE like (Drosophila)
LRFN3 leucine rich repeat and fibronectin type III domain containing 3
LRRC42 leucine rich repeat containing 42
LRRC6 leucine rich repeat containing 6
ME3 malic enzyme 3, NADP(+)-dependent, mitochondrial
MED4 mediator complex subunit 4
MTA2 metastasis associated 1 family, member 2
NPY1R neuropeptide Y receptor Y1
OR7E47P olfactory receptor, family 7, subfamily E, member 47 pseudogene
OSMR oncostatin M receptor
PACS1 phosphofurin acidic cluster sorting protein 1
PALMD palmdelphin
PGPEP1 pyroglutamyl-peptidase I
PID1 phosphotyrosine interaction domain containing 1
PLEKHA6 pleckstrin homology domain containing, family A member 6
PPL periplakin
PPP1R9A protein phosphatase 1, regulatory subunit 9A
PPP2R3B protein phosphatase 2, regulatory subunit B'', beta
PRKAA2 protein kinase, AMP-activated, alpha 2 catalytic subunit
PRKG2 protein kinase, cGMP-dependent, type II
PTPRS protein tyrosine phosphatase, receptor type, S
SAYSD1 SAYSVFN motif domain containing 1
SEC61A2 Sec61 alpha 2 subunit (S. cerevisiae)
SENP7 SUMO1/sentrin specific peptidase 7
SLC14A1 solute carrier family 14 (urea transporter), member 1 (Kidd blood group)
SLC20A2 solute carrier family 20 (phosphate transporter), member 2
SLC35C1 solute carrier family 35 (GDP-fucose transporter), member C1
SMEK2 SMEK homolog 2, suppressor of mek1 (Dictyostelium)
SPATA7 spermatogenesis associated 7
SPIDR scaffolding protein involved in DNA repair
SPRYD7 SPRY domain containing 7
SPSB1 splA/ryanodine receptor domain and SOCS box containing 1
STARD3 StAR-related lipid transfer (START) domain containing 3
SUV39H2 suppressor of variegation 3-9 homolog 2 (Drosophila)
TAF13 TAF13 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 18kDa
TMEM132A transmembrane protein 132A
TMEM183A transmembrane protein 183A
TMEM186 transmembrane protein 186
TMEM209 transmembrane protein 209
UBQLN4 ubiquilin 4
XAB2 XPA binding protein 2
ZAK sterile alpha motif and leucine zipper containing kinase AZK
ZBTB10 zinc finger and BTB domain containing 10
ZNF286A zinc finger protein 286A
ZNF552 zinc finger protein 552
ZNF675 zinc finger protein 675
ZNF74 zinc finger protein 74