thiocolchicoside-5520 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the thiocolchicoside-5520 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
A4GNT alpha-1,4-N-acetylglucosaminyltransferase
ACTL8 actin-like 8
ADD2 adducin 2 (beta)
AK1 adenylate kinase 1
AKAP8L A kinase (PRKA) anchor protein 8-like
AKR1B1 aldo-keto reductase family 1, member B1 (aldose reductase)
AKT3 v-akt murine thymoma viral oncogene homolog 3
APOM apolipoprotein M
ATP6V0A1 ATPase, H+ transporting, lysosomal V0 subunit a1
BAZ2A bromodomain adjacent to zinc finger domain, 2A
BRF1 BRF1, RNA polymerase III transcription initiation factor 90 kDa subunit
BRF2 BRF2, RNA polymerase III transcription initiation factor 50 kDa subunit
BST2 bone marrow stromal cell antigen 2
C21ORF2 chromosome 21 open reading frame 2
CABIN1 calcineurin binding protein 1
CAPG capping protein (actin filament), gelsolin-like
CCL22 chemokine (C-C motif) ligand 22
CDK10 cyclin-dependent kinase 10
CEP164 centrosomal protein 164kDa
CFAP45 cilia and flagella associated protein 45
COL5A2 collagen, type V, alpha 2
CSF1 colony stimulating factor 1 (macrophage)
CXCR3 chemokine (C-X-C motif) receptor 3
DDX58 DEAD (Asp-Glu-Ala-Asp) box polypeptide 58
DEFA5 defensin, alpha 5, Paneth cell-specific
DRD1 dopamine receptor D1
ESR1 estrogen receptor 1
FLJ22184
GGA1 golgi-associated, gamma adaptin ear containing, ARF binding protein 1
GGT1 gamma-glutamyltransferase 1
GMPR guanosine monophosphate reductase
GSK3A glycogen synthase kinase 3 alpha
HECW1 HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1
HLA-DOA major histocompatibility complex, class II, DO alpha
HOXB5 homeobox B5
IFI6 interferon, alpha-inducible protein 6
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
IFITM1 interferon induced transmembrane protein 1
IL22 interleukin 22
IQCC IQ motif containing C
IRF7 interferon regulatory factor 7
IRF9 interferon regulatory factor 9
IRS2 insulin receptor substrate 2
ISG15 ISG15 ubiquitin-like modifier
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)
ITIH2 inter-alpha-trypsin inhibitor heavy chain 2
ITPR3 inositol 1,4,5-trisphosphate receptor, type 3
KCND3 potassium channel, voltage gated Shal related subfamily D, member 3
KIAA0930 KIAA0930
LILRB2 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 2
LRRC61 leucine rich repeat containing 61
MIER2 mesoderm induction early response 1, family member 2
MXRA8 matrix-remodelling associated 8
NBEAL2 neurobeachin-like 2
OAS1 2'-5'-oligoadenylate synthetase 1, 40/46kDa
OGFR opioid growth factor receptor
OR2H2 olfactory receptor, family 2, subfamily H, member 2
PARP12 poly (ADP-ribose) polymerase family, member 12
PATZ1 POZ (BTB) and AT hook containing zinc finger 1
PAX2 paired box 2
PCBP3 poly(rC) binding protein 3
PCDHB13 protocadherin beta 13
PCDHB3 protocadherin beta 3
PHEX phosphate regulating endopeptidase homolog, X-linked
PIK3IP1 phosphoinositide-3-kinase interacting protein 1
PMS2P3 postmeiotic segregation increased 2 pseudogene 3
POFUT1 protein O-fucosyltransferase 1
PRKX protein kinase, X-linked
PRPH2 peripherin 2 (retinal degeneration, slow)
PSMD5 proteasome (prosome, macropain) 26S subunit, non-ATPase, 5
QPCTL glutaminyl-peptide cyclotransferase-like
QTRT1 queuine tRNA-ribosyltransferase 1
RAB3D RAB3D, member RAS oncogene family
RAC2 ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)
RIMS2 regulating synaptic membrane exocytosis 2
RPH3A rabphilin 3A
RSG1 REM2 and RAB-like small GTPase 1
RYR3 ryanodine receptor 3
S100A4 S100 calcium binding protein A4
SFI1 Sfi1 homolog, spindle assembly associated (yeast)
SIRT3 sirtuin 3
SLAMF8 SLAM family member 8
SLC12A4 solute carrier family 12 (potassium/chloride transporter), member 4
SP110 SP110 nuclear body protein
SPHK2 sphingosine kinase 2
ST6GAL1 ST6 beta-galactosamide alpha-2,6-sialyltranferase 1
STS steroid sulfatase (microsomal), isozyme S
STX7 syntaxin 7
SUGP1 SURP and G patch domain containing 1
SUN1 Sad1 and UNC84 domain containing 1
TAPBP TAP binding protein (tapasin)
TBC1D17 TBC1 domain family, member 17
TBC1D22A TBC1 domain family, member 22A
TMEM63A transmembrane protein 63A
TOP3A topoisomerase (DNA) III alpha
TUBBP5 tubulin, beta pseudogene 5
TWISTNB TWIST neighbor
WNK1 WNK lysine deficient protein kinase 1
XPNPEP1 X-prolyl aminopeptidase (aminopeptidase P) 1, soluble
ZFPL1 zinc finger protein-like 1

decreased expression

Symbol Name
ACTR8 ARP8 actin-related protein 8 homolog (yeast)
ALKBH4 alkB, alkylation repair homolog 4 (E. coli)
ARID3B AT rich interactive domain 3B (BRIGHT-like)
ATG7 autophagy related 7
C5ORF45 chromosome 5 open reading frame 45
C7ORF43 chromosome 7 open reading frame 43
CALCOCO1 calcium binding and coiled-coil domain 1
CBX4 chromobox homolog 4
CCDC170 coiled-coil domain containing 170
CCDC85C coiled-coil domain containing 85C
CD83 CD83 molecule
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha
CHPF chondroitin polymerizing factor
CLEC4E C-type lectin domain family 4, member E
CNGB3 cyclic nucleotide gated channel beta 3
CRELD1 cysteine-rich with EGF-like domains 1
CWC25 CWC25 spliceosome-associated protein homolog (S. cerevisiae)
DGCR11 DiGeorge syndrome critical region gene 11 (non-protein coding)
DHRS3 dehydrogenase/reductase (SDR family) member 3
DNA2 DNA replication helicase/nuclease 2
DNAJC28 DnaJ (Hsp40) homolog, subfamily C, member 28
DZANK1 double zinc ribbon and ankyrin repeat domains 1
EFNA3 ephrin-A3
ELP4 elongator acetyltransferase complex subunit 4
ELSPBP1 epididymal sperm binding protein 1
FANCC Fanconi anemia, complementation group C
FANCE Fanconi anemia, complementation group E
FILIP1L filamin A interacting protein 1-like
FKBPL FK506 binding protein like
GCNT1 glucosaminyl (N-acetyl) transferase 1, core 2
GNB1L guanine nucleotide binding protein (G protein), beta polypeptide 1-like
GPR19 G protein-coupled receptor 19
GPX2 glutathione peroxidase 2
GTPBP2 GTP binding protein 2
GUSBP3 glucuronidase, beta pseudogene 3
HIST1H2AJ histone cluster 1, H2aj
HIST1H2AL histone cluster 1, H2al
HS3ST3A1 heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1
HYAL2 hyaluronoglucosaminidase 2
IFNAR1 interferon (alpha, beta and omega) receptor 1
IFT22 intraflagellar transport 22
KLHL2 kelch-like family member 2
KRT8P12 keratin 8 pseudogene 12
LCP1 lymphocyte cytosolic protein 1 (L-plastin)
LIN7B lin-7 homolog B (C. elegans)
LRP5 low density lipoprotein receptor-related protein 5
LRP5L low density lipoprotein receptor-related protein 5-like
LRRC20 leucine rich repeat containing 20
MAGEF1 melanoma antigen family F1
MAP9 microtubule-associated protein 9
MBTD1 mbt domain containing 1
MINOS1P1 mitochondrial inner membrane organizing system 1 pseudogene 1
MORC3 MORC family CW-type zinc finger 3
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding)
NUDT13 nudix (nucleoside diphosphate linked moiety X)-type motif 13
NUP62CL nucleoporin 62kDa C-terminal like
ONECUT2 one cut homeobox 2
OR7E156P olfactory receptor, family 7, subfamily E, member 156 pseudogene
P3H1 prolyl 3-hydroxylase 1
PCBP4 poly(rC) binding protein 4
PIK3C2B phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta
PITX2 paired-like homeodomain 2
PLA2G3 phospholipase A2, group III
PLCXD1 phosphatidylinositol-specific phospholipase C, X domain containing 1
PLEKHO1 pleckstrin homology domain containing, family O member 1
POLE polymerase (DNA directed), epsilon, catalytic subunit
POLR3D polymerase (RNA) III (DNA directed) polypeptide D, 44kDa
PPIP5K1 diphosphoinositol pentakisphosphate kinase 1
PPP2R5D protein phosphatase 2, regulatory subunit B', delta
PTK6 protein tyrosine kinase 6
SARS2 seryl-tRNA synthetase 2, mitochondrial
SCHIP1 schwannomin interacting protein 1
SEC22A SEC22 vesicle trafficking protein homolog A (S. cerevisiae)
SF3B3 splicing factor 3b, subunit 3, 130kDa
SGCG sarcoglycan, gamma (35kDa dystrophin-associated glycoprotein)
SIRAL2 SIR2 antiphage like 2
SIRT6 sirtuin 6
SLC44A1 solute carrier family 44 (choline transporter), member 1
SMYD5 SMYD family member 5
SRPX sushi-repeat containing protein, X-linked
STARD13 StAR-related lipid transfer (START) domain containing 13
STBD1 starch binding domain 1
TBP TATA box binding protein
THBS3 thrombospondin 3
TMEM165 transmembrane protein 165
TMEM183A transmembrane protein 183A
TMEM2 transmembrane protein 2
TNFSF9 tumor necrosis factor (ligand) superfamily, member 9
TNKS2 tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2
TRIB1 tribbles pseudokinase 1
TTC30A tetratricopeptide repeat domain 30A
VPS39 vacuolar protein sorting 39 homolog (S. cerevisiae)
VWA1 von Willebrand factor A domain containing 1
WDR19 WD repeat domain 19
ZBED1 zinc finger, BED-type containing 1
ZNF652 zinc finger protein 652
ZNF668 zinc finger protein 668
ZNF675 zinc finger protein 675