| Dataset | GO Molecular Function Annotations 2025 |
| Category | structural or functional annotations |
| Type | molecular function |
| Description | Catalysis of the reaction: RCO-SR' + H2O = RCOOH + HSR'. This reaction is the hydrolysis of a thiolester bond, an ester formed from a carboxylic acid and a thiol (i.e., RCO-SR'), such as that found in acetyl-coenzyme A. (Gene Ontology, GO_0016790) |
| External Link | http://amigo.geneontology.org/amigo/term/GO:0016790 |
| Similar Terms | |
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5 genes performing the thiolester hydrolase activity molecular function from the curated GO Molecular Function Annotations 2025 dataset.