thioperamide-3055 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the thioperamide-3055 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AAK1 AP2 associated kinase 1
ALDOB aldolase B, fructose-bisphosphate
ALK anaplastic lymphoma receptor tyrosine kinase
ASAP3 ArfGAP with SH3 domain, ankyrin repeat and PH domain 3
ATP2B3 ATPase, Ca++ transporting, plasma membrane 3
ATP9A ATPase, class II, type 9A
AURKA aurora kinase A
BAZ2A bromodomain adjacent to zinc finger domain, 2A
BMPR2 bone morphogenetic protein receptor, type II (serine/threonine kinase)
CACNA2D1 calcium channel, voltage-dependent, alpha 2/delta subunit 1
CC2D1A coiled-coil and C2 domain containing 1A
CCDC181 coiled-coil domain containing 181
CD209 CD209 molecule
CDC42EP2 CDC42 effector protein (Rho GTPase binding) 2
CEP112 centrosomal protein 112kDa
CHRNE cholinergic receptor, nicotinic, epsilon (muscle)
CLIP1 CAP-GLY domain containing linker protein 1
COL1A2 collagen, type I, alpha 2
COL9A3 collagen, type IX, alpha 3
COLQ collagen-like tail subunit (single strand of homotrimer) of asymmetric acetylcholinesterase
CRABP2 cellular retinoic acid binding protein 2
CYB5A cytochrome b5 type A (microsomal)
CYLC1 cylicin, basic protein of sperm head cytoskeleton 1
CYLD cylindromatosis (turban tumor syndrome)
CYTH1 cytohesin 1
DGKE diacylglycerol kinase, epsilon 64kDa
DKFZP434L187 uncharacterized LOC26082
DMP1 dentin matrix acidic phosphoprotein 1
DPEP2 dipeptidase 2
DRD2 dopamine receptor D2
DUSP1 dual specificity phosphatase 1
DUSP4 dual specificity phosphatase 4
ELAC2 elaC ribonuclease Z 2
ENTPD5 ectonucleoside triphosphate diphosphohydrolase 5
EPHB2 EPH receptor B2
F2R coagulation factor II (thrombin) receptor
FGF18 fibroblast growth factor 18
FSTL3 follistatin-like 3 (secreted glycoprotein)
FUBP1 far upstream element (FUSE) binding protein 1
GABARAPL1 GABA(A) receptor-associated protein like 1
GSTTP1 glutathione S-transferase theta pseudogene 1
GUCY1A3 guanylate cyclase 1, soluble, alpha 3
HCFC1 host cell factor C1
HCG4 HLA complex group 4 (non-protein coding)
HIST1H2BC histone cluster 1, H2bc
HLA-DPA1 major histocompatibility complex, class II, DP alpha 1
ICA1 islet cell autoantigen 1, 69kDa
ID3 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein
IL2RA interleukin 2 receptor, alpha
IL36RN interleukin 36 receptor antagonist
ITGB6 integrin, beta 6
ITGB8 integrin, beta 8
ITM2A integral membrane protein 2A
KAT8 K(lysine) acetyltransferase 8
KLC2 kinesin light chain 2
MAF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog
MCF2 MCF.2 cell line derived transforming sequence
METTL7A methyltransferase like 7A
MTUS1 microtubule associated tumor suppressor 1
MYL4 myosin, light chain 4, alkali; atrial, embryonic
NCAM1 neural cell adhesion molecule 1
NCAPH2 non-SMC condensin II complex, subunit H2
NRAP nebulin-related anchoring protein
OAS1 2'-5'-oligoadenylate synthetase 1, 40/46kDa
PAX8 paired box 8
PCLO piccolo presynaptic cytomatrix protein
PDE11A phosphodiesterase 11A
PDE1C phosphodiesterase 1C, calmodulin-dependent 70kDa
PDK4 pyruvate dehydrogenase kinase, isozyme 4
PKNOX1 PBX/knotted 1 homeobox 1
PPP1R16B protein phosphatase 1, regulatory subunit 16B
PRDM9 PR domain containing 9
PTHLH parathyroid hormone-like hormone
PTPN13 protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase)
PVT1 Pvt1 oncogene (non-protein coding)
RGS9 regulator of G-protein signaling 9
RPL10L ribosomal protein L10-like
RUFY3 RUN and FYVE domain containing 3
SEMA4F sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4F
SIGLEC1 sialic acid binding Ig-like lectin 1, sialoadhesin
SIM2 single-minded family bHLH transcription factor 2
SLC22A7 solute carrier family 22 (organic anion transporter), member 7
SLC7A8 solute carrier family 7 (amino acid transporter light chain, L system), member 8
SPEF1 sperm flagellar 1
SPTB spectrin, beta, erythrocytic
TACR1 tachykinin receptor 1
TBX6 T-box 6
TLE2 transducin-like enhancer of split 2
TLX3 T-cell leukemia homeobox 3
TMC7 transmembrane channel-like 7
TMEM180 transmembrane protein 180
TNFRSF10D tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain
TNP2 transition protein 2 (during histone to protamine replacement)
TUBA4B tubulin, alpha 4b
UGT2B17 UDP glucuronosyltransferase 2 family, polypeptide B17
WIZ widely interspaced zinc finger motifs
YBX2 Y box binding protein 2
ZNF440 zinc finger protein 440

decreased expression

Symbol Name
ABL2 ABL proto-oncogene 2, non-receptor tyrosine kinase
ALDOAP2 aldolase A, fructose-bisphosphate pseudogene 2
ALS2CL ALS2 C-terminal like
ANKRD55 ankyrin repeat domain 55
APOBEC2 apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 2
ARAP3 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3
ART1 ADP-ribosyltransferase 1
ATAT1 alpha tubulin acetyltransferase 1
BARX1 BARX homeobox 1
BGLAP bone gamma-carboxyglutamate (gla) protein
C14ORF105 chromosome 14 open reading frame 105
C17ORF53 chromosome 17 open reading frame 53
C4BPA complement component 4 binding protein, alpha
C5ORF45 chromosome 5 open reading frame 45
C6ORF47 chromosome 6 open reading frame 47
C8A complement component 8, alpha polypeptide
C9ORF9 chromosome 9 open reading frame 9
CASS4 Cas scaffolding protein family member 4
CBR3 carbonyl reductase 3
CBX7 chromobox homolog 7
CCDC186 coiled-coil domain containing 186
CCDC71 coiled-coil domain containing 71
CDKL1 cyclin-dependent kinase-like 1 (CDC2-related kinase)
CDY1 chromodomain protein, Y-linked, 1
CST1 cystatin SN
DGKG diacylglycerol kinase, gamma 90kDa
DHRS9 dehydrogenase/reductase (SDR family) member 9
ERICH1 glutamate-rich 1
ERMAP erythroblast membrane-associated protein (Scianna blood group)
FAM102A family with sequence similarity 102, member A
FKBP9 FK506 binding protein 9, 63 kDa
FMOD fibromodulin
GATA4 GATA binding protein 4
GIF gastric intrinsic factor (vitamin B synthesis)
GLRA1 glycine receptor, alpha 1
GNG4 guanine nucleotide binding protein (G protein), gamma 4
GNL1 guanine nucleotide binding protein-like 1
GZMK granzyme K (granzyme 3; tryptase II)
HAMP hepcidin antimicrobial peptide
HIST1H1B histone cluster 1, H1b
HIST1H2BN histone cluster 1, H2bn
HIST1H3G histone cluster 1, H3g
HOXD10 homeobox D10
IFI30 interferon, gamma-inducible protein 30
IL3RA interleukin 3 receptor, alpha (low affinity)
KIAA0753 KIAA0753
KIF17 kinesin family member 17
KL klotho
KRT31 keratin 31, type I
LPAR3 lysophosphatidic acid receptor 3
LRP6 low density lipoprotein receptor-related protein 6
MEP1B meprin A, beta
MRPL44 mitochondrial ribosomal protein L44
MUC2 mucin 2, oligomeric mucus/gel-forming
NBR2 neighbor of BRCA1 gene 2 (non-protein coding)
NCS1 neuronal calcium sensor 1
NFE2L3 nuclear factor, erythroid 2-like 3
NINJ1 ninjurin 1
OXTR oxytocin receptor
PARP16 poly (ADP-ribose) polymerase family, member 16
PGPEP1 pyroglutamyl-peptidase I
PNPLA3 patatin-like phospholipase domain containing 3
PODXL2 podocalyxin-like 2
PRAF2 PRA1 domain family, member 2
RAB40A RAB40A, member RAS oncogene family
RAPGEFL1 Rap guanine nucleotide exchange factor (GEF)-like 1
RARRES2 retinoic acid receptor responder (tazarotene induced) 2
RCAN3 RCAN family member 3
RHOB ras homolog family member B
RNF25 ring finger protein 25
RPL23AP53 ribosomal protein L23a pseudogene 53
SEZ6L2 seizure related 6 homolog (mouse)-like 2
SGPP1 sphingosine-1-phosphate phosphatase 1
SLC17A2 solute carrier family 17, member 2
SLC6A20 solute carrier family 6 (proline IMINO transporter), member 20
SLC9A1 solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1
SPATA20 spermatogenesis associated 20
STAG3L4 stromal antigen 3-like 4 (pseudogene)
STARD13 StAR-related lipid transfer (START) domain containing 13
SYNDIG1 synapse differentiation inducing 1
TBC1D19 TBC1 domain family, member 19
TLR6 toll-like receptor 6
TMEM242 transmembrane protein 242
TNFRSF13B tumor necrosis factor receptor superfamily, member 13B
TONSL tonsoku-like, DNA repair protein
TRAF2 TNF receptor-associated factor 2
TRPC5 transient receptor potential cation channel, subfamily C, member 5
TRPS1 trichorhinophalangeal syndrome I
UCN urocortin
WDR25 WD repeat domain 25
ZNF155 zinc finger protein 155
ZNF219 zinc finger protein 219
ZNF385D zinc finger protein 385D
ZNF442 zinc finger protein 442
ZNF492 zinc finger protein 492
ZNF574 zinc finger protein 574
ZNF606 zinc finger protein 606
ZNF696 zinc finger protein 696
ZNHIT2 zinc finger, HIT-type containing 2