| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
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196 genes differentially expressed following the thioperamide-3392 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| A4GALT | alpha 1,4-galactosyltransferase |
| ACSBG1 | acyl-CoA synthetase bubblegum family member 1 |
| ACSL5 | acyl-CoA synthetase long-chain family member 5 |
| ACTN1 | actinin, alpha 1 |
| ADAM22 | ADAM metallopeptidase domain 22 |
| ADCY2 | adenylate cyclase 2 (brain) |
| AMPD3 | adenosine monophosphate deaminase 3 |
| AP5Z1 | adaptor-related protein complex 5, zeta 1 subunit |
| APOBEC1 | apolipoprotein B mRNA editing enzyme, catalytic polypeptide 1 |
| ARVCF | armadillo repeat gene deleted in velocardiofacial syndrome |
| ATF3 | activating transcription factor 3 |
| ATP10B | ATPase, class V, type 10B |
| BAZ2A | bromodomain adjacent to zinc finger domain, 2A |
| BCL2L10 | BCL2-like 10 (apoptosis facilitator) |
| BCL6 | B-cell CLL/lymphoma 6 |
| C10ORF12 | chromosome 10 open reading frame 12 |
| CAMK2G | calcium/calmodulin-dependent protein kinase II gamma |
| CCDC40 | coiled-coil domain containing 40 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 |
| CEP162 | centrosomal protein 162kDa |
| CERS4 | ceramide synthase 4 |
| CHRNB1 | cholinergic receptor, nicotinic, beta 1 (muscle) |
| COL13A1 | collagen, type XIII, alpha 1 |
| COX6A2 | cytochrome c oxidase subunit VIa polypeptide 2 |
| CRTC1 | CREB regulated transcription coactivator 1 |
| CSF2RB | colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage) |
| DOCK3 | dedicator of cytokinesis 3 |
| DST | dystonin |
| EGR1 | early growth response 1 |
| ERAP1 | endoplasmic reticulum aminopeptidase 1 |
| ERCC2 | excision repair cross-complementation group 2 |
| ETV2 | ets variant 2 |
| FAM168A | family with sequence similarity 168, member A |
| FGA | fibrinogen alpha chain |
| FOSL2 | FOS-like antigen 2 |
| FRMD1 | FERM domain containing 1 |
| FUT3 | fucosyltransferase 3 (galactoside 3(4)-L-fucosyltransferase, Lewis blood group) |
| GREB1L | growth regulation by estrogen in breast cancer-like |
| GRM4 | glutamate receptor, metabotropic 4 |
| HCN2 | hyperpolarization activated cyclic nucleotide gated potassium channel 2 |
| HEY2 | hes-related family bHLH transcription factor with YRPW motif 2 |
| HFE | hemochromatosis |
| HSD3B1 | hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 |
| ITGA2B | integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41) |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 |
| JPH3 | junctophilin 3 |
| KAZN | kazrin, periplakin interacting protein |
| KCNAB1 | potassium channel, voltage gated subfamily A regulatory beta subunit 1 |
| KLHL35 | kelch-like family member 35 |
| LEFTY1 | left-right determination factor 1 |
| LENEP | lens epithelial protein |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 |
| MAFF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F |
| MARK4 | MAP/microtubule affinity-regulating kinase 4 |
| MUC5B | mucin 5B, oligomeric mucus/gel-forming |
| N4BP2L1 | NEDD4 binding protein 2-like 1 |
| NF2 | neurofibromin 2 (merlin) |
| NR4A1 | nuclear receptor subfamily 4, group A, member 1 |
| NTRK2 | neurotrophic tyrosine kinase, receptor, type 2 |
| OSBPL2 | oxysterol binding protein-like 2 |
| PAPPA2 | pappalysin 2 |
| PDE4DIP | phosphodiesterase 4D interacting protein |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 |
| PLA2G6 | phospholipase A2, group VI (cytosolic, calcium-independent) |
| POFUT1 | protein O-fucosyltransferase 1 |
| PRKD3 | protein kinase D3 |
| PRMT2 | protein arginine methyltransferase 2 |
| RAB40C | RAB40C, member RAS oncogene family |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 |
| RQCD1 | RCD1 required for cell differentiation1 homolog (S. pombe) |
| RUNX1T1 | runt-related transcription factor 1; translocated to, 1 (cyclin D-related) |
| SALL1 | spalt-like transcription factor 1 |
| SETD1B | SET domain containing 1B |
| SFPQ | splicing factor proline/glutamine-rich |
| SH2D3A | SH2 domain containing 3A |
| SH3GL3 | SH3-domain GRB2-like 3 |
| SKIL | SKI-like proto-oncogene |
| SNCA | synuclein, alpha (non A4 component of amyloid precursor) |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 |
| SSTR4 | somatostatin receptor 4 |
| STS | steroid sulfatase (microsomal), isozyme S |
| SYN2 | synapsin II |
| SZT2 | seizure threshold 2 homolog (mouse) |
| TGM2 | transglutaminase 2 |
| TLE3 | transducin-like enhancer of split 3 |
| TMCC2 | transmembrane and coiled-coil domain family 2 |
| TPP1 | tripeptidyl peptidase I |
| TREM2 | triggering receptor expressed on myeloid cells 2 |
| TRPC4 | transient receptor potential cation channel, subfamily C, member 4 |
| TRPM2 | transient receptor potential cation channel, subfamily M, member 2 |
| TTC33 | tetratricopeptide repeat domain 33 |
| TTC39A | tetratricopeptide repeat domain 39A |
| TXNIP | thioredoxin interacting protein |
| UBA7 | ubiquitin-like modifier activating enzyme 7 |
| UCP1 | uncoupling protein 1 (mitochondrial, proton carrier) |
| WNT10B | wingless-type MMTV integration site family, member 10B |
| YY2 | YY2 transcription factor |
| ZNF76 | zinc finger protein 76 |
| Symbol | Name |
|---|---|
| ACTL8 | actin-like 8 |
| ADCK4 | aarF domain containing kinase 4 |
| ARHGEF28 | Rho guanine nucleotide exchange factor (GEF) 28 |
| ARHGEF6 | Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6 |
| ATP6V1B1 | ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B1 |
| BFSP1 | beaded filament structural protein 1, filensin |
| BLNK | B-cell linker |
| C14ORF79 | chromosome 14 open reading frame 79 |
| C5 | complement component 5 |
| CAMK4 | calcium/calmodulin-dependent protein kinase IV |
| CCDC132 | coiled-coil domain containing 132 |
| CCDC134 | coiled-coil domain containing 134 |
| CCNO | cyclin O |
| CD34 | CD34 molecule |
| CD83 | CD83 molecule |
| CDK6 | cyclin-dependent kinase 6 |
| CDKN2D | cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4) |
| CHM | choroideremia (Rab escort protein 1) |
| CHRNA2 | cholinergic receptor, nicotinic, alpha 2 (neuronal) |
| CLDN9 | claudin 9 |
| COPZ2 | coatomer protein complex, subunit zeta 2 |
| CORO7 | coronin 7 |
| CRIP1 | cysteine-rich protein 1 (intestinal) |
| CTRL | chymotrypsin-like |
| DENND5B | DENN/MADD domain containing 5B |
| DNMT3A | DNA (cytosine-5-)-methyltransferase 3 alpha |
| ETAA1 | Ewing tumor-associated antigen 1 |
| ETV6 | ets variant 6 |
| FARP2 | FERM, RhoGEF and pleckstrin domain protein 2 |
| FGF23 | fibroblast growth factor 23 |
| FSCN3 | fascin actin-bundling protein 3, testicular |
| GAST | gastrin |
| GJA8 | gap junction protein, alpha 8, 50kDa |
| GMPR | guanosine monophosphate reductase |
| GPATCH2L | G patch domain containing 2-like |
| GPR143 | G protein-coupled receptor 143 |
| GPRIN2 | G protein regulated inducer of neurite outgrowth 2 |
| GUCY1B2 | guanylate cyclase 1, soluble, beta 2 (pseudogene) |
| HIST1H4A | histone cluster 1, H4a |
| HLA-DMB | major histocompatibility complex, class II, DM beta |
| HLCS | holocarboxylase synthetase (biotin-(proprionyl-CoA-carboxylase (ATP-hydrolysing)) ligase) |
| HMOX1 | heme oxygenase 1 |
| HS3ST3A1 | heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1 |
| HSD17B11 | hydroxysteroid (17-beta) dehydrogenase 11 |
| INHA | inhibin, alpha |
| IQCG | IQ motif containing G |
| ITGA5 | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) |
| KIAA0355 | KIAA0355 |
| KRT9 | keratin 9, type I |
| LAIR2 | leukocyte-associated immunoglobulin-like receptor 2 |
| LINC01587 | long intergenic non-protein coding RNA 1587 |
| LLPH | LLP homolog, long-term synaptic facilitation (Aplysia) |
| LOC100131532 | uncharacterized LOC100131532 |
| LOC390998 | ribosomal protein L10 pseudogene |
| LRRC15 | leucine rich repeat containing 15 |
| LYRM9 | LYR motif containing 9 |
| MAGEB2 | melanoma antigen family B2 |
| MAPK8IP1 | mitogen-activated protein kinase 8 interacting protein 1 |
| MATK | megakaryocyte-associated tyrosine kinase |
| MEFV | Mediterranean fever |
| MFAP2 | microfibrillar-associated protein 2 |
| MLLT4-AS1 | MLLT4 antisense RNA 1 (head to head) |
| MOCS3 | molybdenum cofactor synthesis 3 |
| MTL5 | metallothionein-like 5, testis-specific (tesmin) |
| MUC3A | mucin 3A, cell surface associated |
| NACA2 | nascent polypeptide-associated complex alpha subunit 2 |
| NKX3-2 | NK3 homeobox 2 |
| NLRX1 | NLR family member X1 |
| NUDT18 | nudix (nucleoside diphosphate linked moiety X)-type motif 18 |
| OCLM | oculomedin |
| PDE6B | phosphodiesterase 6B, cGMP-specific, rod, beta |
| PDIA3 | protein disulfide isomerase family A, member 3 |
| PICK1 | protein interacting with PRKCA 1 |
| POM121L2 | POM121 transmembrane nucleoporin-like 2 |
| PSCA | prostate stem cell antigen |
| RND1 | Rho family GTPase 1 |
| SAYSD1 | SAYSVFN motif domain containing 1 |
| SCN10A | sodium channel, voltage gated, type X alpha subunit |
| SDS | serine dehydratase |
| SEMA4D | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D |
| SERGEF | secretion regulating guanine nucleotide exchange factor |
| SLC12A9 | solute carrier family 12, member 9 |
| SLC3A1 | solute carrier family 3 (amino acid transporter heavy chain), member 1 |
| SLC4A8 | solute carrier family 4, sodium bicarbonate cotransporter, member 8 |
| SPEG | SPEG complex locus |
| SRPX | sushi-repeat containing protein, X-linked |
| TBC1D2 | TBC1 domain family, member 2 |
| THSD4 | thrombospondin, type I, domain containing 4 |
| TM4SF4 | transmembrane 4 L six family member 4 |
| TNFSF18 | tumor necrosis factor (ligand) superfamily, member 18 |
| TNS2 | tensin 2 |
| TOP3B | topoisomerase (DNA) III beta |
| TUBBP5 | tubulin, beta pseudogene 5 |
| WDR78 | WD repeat domain 78 |
| ZKSCAN3 | zinc finger with KRAB and SCAN domains 3 |
| ZNF137P | zinc finger protein 137, pseudogene |
| ZNF557 | zinc finger protein 557 |
| ZNF668 | zinc finger protein 668 |