thioperamide-5270 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

196 genes differentially expressed following the thioperamide-5270 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
A2M alpha-2-macroglobulin
AAK1 AP2 associated kinase 1
ACADS acyl-CoA dehydrogenase, C-2 to C-3 short chain
ADAMTS13 ADAM metallopeptidase with thrombospondin type 1 motif, 13
ANKRD55 ankyrin repeat domain 55
ARAP1 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1
ARSD arylsulfatase D
ATF7IP activating transcription factor 7 interacting protein
ATG10 autophagy related 10
BAZ2A bromodomain adjacent to zinc finger domain, 2A
BIRC7 baculoviral IAP repeat containing 7
CACNA1I calcium channel, voltage-dependent, T type, alpha 1I subunit
CD4 CD4 molecule
CD6 CD6 molecule
CD70 CD70 molecule
CD83 CD83 molecule
CDKN2D cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)
CDO1 cysteine dioxygenase type 1
CEP41 centrosomal protein 41kDa
CLDN17 claudin 17
CLDN18 claudin 18
CNTN1 contactin 1
COL14A1 collagen, type XIV, alpha 1
COL19A1 collagen, type XIX, alpha 1
COL1A1 collagen, type I, alpha 1
CRHR2 corticotropin releasing hormone receptor 2
CTSS cathepsin S
CYP2W1 cytochrome P450, family 2, subfamily W, polypeptide 1
DCN decorin
DGCR2 DiGeorge syndrome critical region gene 2
DIAPH2-AS1 DIAPH2 antisense RNA 1
DMXL2 Dmx-like 2
DUSP6 dual specificity phosphatase 6
EGR3 early growth response 3
EHD2 EH-domain containing 2
ENOX1 ecto-NOX disulfide-thiol exchanger 1
ERCC2 excision repair cross-complementation group 2
FBXO41 F-box protein 41
FN1 fibronectin 1
FOXG1 forkhead box G1
GGT1 gamma-glutamyltransferase 1
GLB1L galactosidase, beta 1-like
GP2 glycoprotein 2 (zymogen granule membrane)
GREB1 growth regulation by estrogen in breast cancer 1
GRIA4 glutamate receptor, ionotropic, AMPA 4
GSTTP1 glutathione S-transferase theta pseudogene 1
HFE hemochromatosis
IL18 interleukin 18
ING2 inhibitor of growth family, member 2
IQCC IQ motif containing C
ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)
KSR1 kinase suppressor of ras 1
LAIR1 leukocyte-associated immunoglobulin-like receptor 1
LEFTY2 left-right determination factor 2
LOC284244 uncharacterized LOC284244
MALL mal, T-cell differentiation protein-like
ME1 malic enzyme 1, NADP(+)-dependent, cytosolic
METTL7A methyltransferase like 7A
MMRN2 multimerin 2
MTA1 metastasis associated 1
MX1 MX dynamin-like GTPase 1
NMNAT2 nicotinamide nucleotide adenylyltransferase 2
ONECUT1 one cut homeobox 1
ORAI2 ORAI calcium release-activated calcium modulator 2
PADI3 peptidyl arginine deiminase, type III
PAK4 p21 protein (Cdc42/Rac)-activated kinase 4
PCBP3 poly(rC) binding protein 3
PCDH1 protocadherin 1
PCDHGB6 protocadherin gamma subfamily B, 6
PIM1 Pim-1 proto-oncogene, serine/threonine kinase
PITPNM1 phosphatidylinositol transfer protein, membrane-associated 1
PKNOX1 PBX/knotted 1 homeobox 1
PLTP phospholipid transfer protein
PLXNB3 plexin B3
PRSS12 protease, serine, 12 (neurotrypsin, motopsin)
PTAFR platelet-activating factor receptor
PTGER3 prostaglandin E receptor 3 (subtype EP3)
RAPGEFL1 Rap guanine nucleotide exchange factor (GEF)-like 1
RASAL2 RAS protein activator like 2
RGS12 regulator of G-protein signaling 12
RPL35A ribosomal protein L35a
RRAGD Ras-related GTP binding D
RUNX1 runt-related transcription factor 1
SDC3 syndecan 3
SERPINB3 serpin peptidase inhibitor, clade B (ovalbumin), member 3
SLC26A4 solute carrier family 26 (anion exchanger), member 4
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1
SLC7A8 solute carrier family 7 (amino acid transporter light chain, L system), member 8
SRF serum response factor (c-fos serum response element-binding transcription factor)
SSTR5 somatostatin receptor 5
TBC1D2 TBC1 domain family, member 2
TBR1 T-box, brain, 1
TJAP1 tight junction associated protein 1 (peripheral)
TRPC4 transient receptor potential cation channel, subfamily C, member 4
UNC119 unc-119 homolog (C. elegans)
UNC13A unc-13 homolog A (C. elegans)
XYLB xylulokinase homolog (H. influenzae)
ZFP36L2 ZFP36 ring finger protein-like 2
ZNF37BP zinc finger protein 37B, pseudogene

decreased expression

Symbol Name
ACTL8 actin-like 8
APBB3 amyloid beta (A4) precursor protein-binding, family B, member 3
ARC activity-regulated cytoskeleton-associated protein
ARHGDIG Rho GDP dissociation inhibitor (GDI) gamma
ARRB1 arrestin, beta 1
AUTS2 autism susceptibility candidate 2
BLNK B-cell linker
BRINP2 bone morphogenetic protein/retinoic acid inducible neural-specific 2
C17ORF80 chromosome 17 open reading frame 80
C19ORF73 chromosome 19 open reading frame 73
C6ORF47 chromosome 6 open reading frame 47
CARF calcium responsive transcription factor
CCDC68 coiled-coil domain containing 68
CEP85 centrosomal protein 85kDa
CFAP69 cilia and flagella associated protein 69
CHML choroideremia-like (Rab escort protein 2)
CHRNA9 cholinergic receptor, nicotinic, alpha 9 (neuronal)
CLDN15 claudin 15
CNGB3 cyclic nucleotide gated channel beta 3
CNR2 cannabinoid receptor 2 (macrophage)
CXXC4 CXXC finger protein 4
DBF4B DBF4 zinc finger B
DNM1 dynamin 1
DPY19L1P1 DPY19L1 pseudogene 1
DRD1 dopamine receptor D1
FAM110B family with sequence similarity 110, member B
FGF23 fibroblast growth factor 23
FGL1 fibrinogen-like 1
FLT4 fms-related tyrosine kinase 4
FRMD1 FERM domain containing 1
GABRR2 gamma-aminobutyric acid (GABA) A receptor, rho 2
GID4 GID complex subunit 4
GNG13 guanine nucleotide binding protein (G protein), gamma 13
GNG3 guanine nucleotide binding protein (G protein), gamma 3
GPATCH3 G patch domain containing 3
GPR21 G protein-coupled receptor 21
GUCY1A2 guanylate cyclase 1, soluble, alpha 2
HAMP hepcidin antimicrobial peptide
HIST1H1D histone cluster 1, H1d
HIST1H3E histone cluster 1, H3e
HIVEP3 human immunodeficiency virus type I enhancer binding protein 3
HMOX1 heme oxygenase 1
IFI27 interferon, alpha-inducible protein 27
IL4R interleukin 4 receptor
IMPDH1 IMP (inosine 5'-monophosphate) dehydrogenase 1
IRF2BP1 interferon regulatory factor 2 binding protein 1
KDM8 lysine (K)-specific demethylase 8
KLC2 kinesin light chain 2
LAMB3 laminin, beta 3
LRFN3 leucine rich repeat and fibronectin type III domain containing 3
LY6D lymphocyte antigen 6 complex, locus D
MAPK8 mitogen-activated protein kinase 8
MTCP1 mature T-cell proliferation 1
OR2B6 olfactory receptor, family 2, subfamily B, member 6
OR7E156P olfactory receptor, family 7, subfamily E, member 156 pseudogene
P2RY1 purinergic receptor P2Y, G-protein coupled, 1
PCDHB3 protocadherin beta 3
PCTP phosphatidylcholine transfer protein
PDE8B phosphodiesterase 8B
PENK proenkephalin
PIPOX pipecolic acid oxidase
PLEKHO2 pleckstrin homology domain containing, family O member 2
PMCH pro-melanin-concentrating hormone
POFUT1 protein O-fucosyltransferase 1
POLL polymerase (DNA directed), lambda
PTGER2 prostaglandin E receptor 2 (subtype EP2), 53kDa
RAI2 retinoic acid induced 2
RFPL3 ret finger protein-like 3
RGS2 regulator of G-protein signaling 2
RNF122 ring finger protein 122
RNF43 ring finger protein 43
RPAP1 RNA polymerase II associated protein 1
S100A4 S100 calcium binding protein A4
S100A9 S100 calcium binding protein A9
SH3BGR SH3 domain binding glutamate-rich protein
SLC44A1 solute carrier family 44 (choline transporter), member 1
SLC46A3 solute carrier family 46, member 3
STK16 serine/threonine kinase 16
STON1 stonin 1
TARP TCR gamma alternate reading frame protein
TAS2R10 taste receptor, type 2, member 10
TEX14 testis expressed 14
TGFBR1 transforming growth factor, beta receptor 1
TMEM212 transmembrane protein 212
TRAF2 TNF receptor-associated factor 2
TWISTNB TWIST neighbor
USP20 ubiquitin specific peptidase 20
VIPR1 vasoactive intestinal peptide receptor 1
YY2 YY2 transcription factor
ZNF350 zinc finger protein 350
ZNF711 zinc finger protein 711
ZNF747 zinc finger protein 747
ZNF750 zinc finger protein 750
ZNF770 zinc finger protein 770
ZNF862 zinc finger protein 862
ZSWIM1 zinc finger, SWIM-type containing 1