thioperamide-5635 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the thioperamide-5635 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACTN1 actinin, alpha 1
ADM adrenomedullin
AHSP alpha hemoglobin stabilizing protein
APAF1 apoptotic peptidase activating factor 1
APBA1 amyloid beta (A4) precursor protein-binding, family A, member 1
ARNT aryl hydrocarbon receptor nuclear translocator
ARSD arylsulfatase D
ATG10 autophagy related 10
B3GNT4 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 4
CA1 carbonic anhydrase I
CACNA2D2 calcium channel, voltage-dependent, alpha 2/delta subunit 2
CALCR calcitonin receptor
CHRNA3 cholinergic receptor, nicotinic, alpha 3 (neuronal)
CNTFR ciliary neurotrophic factor receptor
COL2A1 collagen, type II, alpha 1
COL5A2 collagen, type V, alpha 2
CYP4F2 cytochrome P450, family 4, subfamily F, polypeptide 2
DDX51 DEAD (Asp-Glu-Ala-Asp) box polypeptide 51
DFNB31 deafness, autosomal recessive 31
DHRS7 dehydrogenase/reductase (SDR family) member 7
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha
DOC2B double C2-like domains, beta
DPF1 D4, zinc and double PHD fingers family 1
DRICH1 aspartate-rich 1
DTNA dystrobrevin, alpha
DTNB dystrobrevin, beta
EFNB3 ephrin-B3
EGR3 early growth response 3
EPHB2 EPH receptor B2
EVA1B eva-1 homolog B (C. elegans)
FBLN1 fibulin 1
FBXO41 F-box protein 41
FEZ1 fasciculation and elongation protein zeta 1 (zygin I)
FGD1 FYVE, RhoGEF and PH domain containing 1
FGFR4 fibroblast growth factor receptor 4
FHIT fragile histidine triad
FLRT2 fibronectin leucine rich transmembrane protein 2
FRMD4B FERM domain containing 4B
FSTL3 follistatin-like 3 (secreted glycoprotein)
GABRB2 gamma-aminobutyric acid (GABA) A receptor, beta 2
HCAR3 hydroxycarboxylic acid receptor 3
HFE hemochromatosis
HIC2 hypermethylated in cancer 2
HIST1H3I histone cluster 1, H3i
HLA-DOA major histocompatibility complex, class II, DO alpha
HLA-J major histocompatibility complex, class I, J (pseudogene)
HSD3B1 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1
IL11 interleukin 11
IL1RN interleukin 1 receptor antagonist
KCNK2 potassium channel, two pore domain subfamily K, member 2
KIF21B kinesin family member 21B
KLHL22 kelch-like family member 22
KRT17 keratin 17, type I
KSR1 kinase suppressor of ras 1
LAMC2 laminin, gamma 2
LAMP1 lysosomal-associated membrane protein 1
LATS1 large tumor suppressor kinase 1
MAP3K8 mitogen-activated protein kinase kinase kinase 8
MARK4 MAP/microtubule affinity-regulating kinase 4
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MEF2C myocyte enhancer factor 2C
MEGF6 multiple EGF-like-domains 6
MUC5B mucin 5B, oligomeric mucus/gel-forming
NAB2 NGFI-A binding protein 2 (EGR1 binding protein 2)
NBL1 neuroblastoma 1, DAN family BMP antagonist
NPTX2 neuronal pentraxin II
OCLM oculomedin
OSBPL7 oxysterol binding protein-like 7
PFKFB2 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2
PLCD1 phospholipase C, delta 1
POMT2 protein-O-mannosyltransferase 2
PON1 paraoxonase 1
RAB33A RAB33A, member RAS oncogene family
RAB40C RAB40C, member RAS oncogene family
RTEL1 regulator of telomere elongation helicase 1
SH2D1A SH2 domain containing 1A
SLCO1B1 solute carrier organic anion transporter family, member 1B1
SLCO1C1 solute carrier organic anion transporter family, member 1C1
SOX2 SRY (sex determining region Y)-box 2
SPAG8 sperm associated antigen 8
SPN sialophorin
SPON1 spondin 1, extracellular matrix protein
SPPL2B signal peptide peptidase like 2B
SRSF7 serine/arginine-rich splicing factor 7
STXBP5L syntaxin binding protein 5-like
TAPBP TAP binding protein (tapasin)
TJAP1 tight junction associated protein 1 (peripheral)
TRIM10 tripartite motif containing 10
UBE3A ubiquitin protein ligase E3A
UBQLN4 ubiquilin 4
USP53 ubiquitin specific peptidase 53
WBP5 WW domain binding protein 5
WDR62 WD repeat domain 62
WNT16 wingless-type MMTV integration site family, member 16
WSCD1 WSC domain containing 1
XRCC6 X-ray repair complementing defective repair in Chinese hamster cells 6
ZBTB18 zinc finger and BTB domain containing 18
ZNF230 zinc finger protein 230
ZNF343 zinc finger protein 343
ZNF589 zinc finger protein 589

decreased expression

Symbol Name
ADTRP androgen-dependent TFPI-regulating protein
AHNAK2 AHNAK nucleoprotein 2
AKR1B1 aldo-keto reductase family 1, member B1 (aldose reductase)
ARID3B AT rich interactive domain 3B (BRIGHT-like)
C14ORF79 chromosome 14 open reading frame 79
C19ORF73 chromosome 19 open reading frame 73
CCDC134 coiled-coil domain containing 134
CDK6 cyclin-dependent kinase 6
CGREF1 cell growth regulator with EF-hand domain 1
CHRNB2 cholinergic receptor, nicotinic, beta 2 (neuronal)
CIC capicua transcriptional repressor
CIDEB cell death-inducing DFFA-like effector b
CLCN6 chloride channel, voltage-sensitive 6
CLIP4 CAP-GLY domain containing linker protein family, member 4
CLSTN2 calsyntenin 2
CRIP1 cysteine-rich protein 1 (intestinal)
CRLF1 cytokine receptor-like factor 1
CSF1R colony stimulating factor 1 receptor
CTSF cathepsin F
CYP2B7P cytochrome P450, family 2, subfamily B, polypeptide 7, pseudogene
DBF4B DBF4 zinc finger B
DOK5 docking protein 5
DRD1 dopamine receptor D1
EPHB6 EPH receptor B6
EPN1 epsin 1
FAM198B family with sequence similarity 198, member B
FGF6 fibroblast growth factor 6
FKBP1B FK506 binding protein 1B, 12.6 kDa
GABRA2 gamma-aminobutyric acid (GABA) A receptor, alpha 2
GABRR2 gamma-aminobutyric acid (GABA) A receptor, rho 2
GFI1 growth factor independent 1 transcription repressor
GPR157 G protein-coupled receptor 157
GPR176 G protein-coupled receptor 176
GPR3 G protein-coupled receptor 3
HAMP hepcidin antimicrobial peptide
HDAC7 histone deacetylase 7
HMHB1 histocompatibility (minor) HB-1
HOXD11 homeobox D11
HYI hydroxypyruvate isomerase (putative)
IBSP integrin-binding sialoprotein
IGSF6 immunoglobulin superfamily, member 6
IL2 interleukin 2
KDM8 lysine (K)-specific demethylase 8
LINC00597 long intergenic non-protein coding RNA 597
LPAR4 lysophosphatidic acid receptor 4
LTBP2 latent transforming growth factor beta binding protein 2
MANBA mannosidase, beta A, lysosomal
MBIP MAP3K12 binding inhibitory protein 1
MNX1 motor neuron and pancreas homeobox 1
MYL5 myosin, light chain 5, regulatory
NACA2 nascent polypeptide-associated complex alpha subunit 2
NTF3 neurotrophin 3
OCA2 oculocutaneous albinism II
OR1G1 olfactory receptor, family 1, subfamily G, member 1
PCDHA5 protocadherin alpha 5
PDE6C phosphodiesterase 6C, cGMP-specific, cone, alpha prime
PDK4 pyruvate dehydrogenase kinase, isozyme 4
PIK3R2 phosphoinositide-3-kinase, regulatory subunit 2 (beta)
PLXNB3 plexin B3
POU4F2 POU class 4 homeobox 2
PRSS53 protease, serine, 53
PYHIN1 pyrin and HIN domain family, member 1
RAB3D RAB3D, member RAS oncogene family
REM1 RAS (RAD and GEM)-like GTP-binding 1
RHBDD3 rhomboid domain containing 3
RHOBTB2 Rho-related BTB domain containing 2
RIN1 Ras and Rab interactor 1
RNF125 ring finger protein 125, E3 ubiquitin protein ligase
RNF2 ring finger protein 2
RNF43 ring finger protein 43
RRH retinal pigment epithelium-derived rhodopsin homolog
S100A2 S100 calcium binding protein A2
S100A7 S100 calcium binding protein A7
S100A9 S100 calcium binding protein A9
SAG S-antigen; retina and pineal gland (arrestin)
SETD1B SET domain containing 1B
SLC12A8 solute carrier family 12, member 8
SLC22A18AS solute carrier family 22 (organic cation transporter), member 18 antisense
SSTR5 somatostatin receptor 5
STAB2 stabilin 2
TAF15 TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa
TEP1 telomerase-associated protein 1
TMEM53 transmembrane protein 53
TMEM8B transmembrane protein 8B
TTLL1 tubulin tyrosine ligase-like family member 1
USP20 ubiquitin specific peptidase 20
USP27X ubiquitin specific peptidase 27, X-linked
VASH2 vasohibin 2
VPS9D1 VPS9 domain containing 1
WNT10B wingless-type MMTV integration site family, member 10B
XDH xanthine dehydrogenase
YY2 YY2 transcription factor
ZBTB48 zinc finger and BTB domain containing 48
ZNF350 zinc finger protein 350
ZNF532 zinc finger protein 532
ZNF574 zinc finger protein 574
ZNF606 zinc finger protein 606
ZNF747 zinc finger protein 747