| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
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198 genes differentially expressed following the thioperamide-5635 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ACTN1 | actinin, alpha 1 |
| ADM | adrenomedullin |
| AHSP | alpha hemoglobin stabilizing protein |
| APAF1 | apoptotic peptidase activating factor 1 |
| APBA1 | amyloid beta (A4) precursor protein-binding, family A, member 1 |
| ARNT | aryl hydrocarbon receptor nuclear translocator |
| ARSD | arylsulfatase D |
| ATG10 | autophagy related 10 |
| B3GNT4 | UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 4 |
| CA1 | carbonic anhydrase I |
| CACNA2D2 | calcium channel, voltage-dependent, alpha 2/delta subunit 2 |
| CALCR | calcitonin receptor |
| CHRNA3 | cholinergic receptor, nicotinic, alpha 3 (neuronal) |
| CNTFR | ciliary neurotrophic factor receptor |
| COL2A1 | collagen, type II, alpha 1 |
| COL5A2 | collagen, type V, alpha 2 |
| CYP4F2 | cytochrome P450, family 4, subfamily F, polypeptide 2 |
| DDX51 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 51 |
| DFNB31 | deafness, autosomal recessive 31 |
| DHRS7 | dehydrogenase/reductase (SDR family) member 7 |
| DNMT3A | DNA (cytosine-5-)-methyltransferase 3 alpha |
| DOC2B | double C2-like domains, beta |
| DPF1 | D4, zinc and double PHD fingers family 1 |
| DRICH1 | aspartate-rich 1 |
| DTNA | dystrobrevin, alpha |
| DTNB | dystrobrevin, beta |
| EFNB3 | ephrin-B3 |
| EGR3 | early growth response 3 |
| EPHB2 | EPH receptor B2 |
| EVA1B | eva-1 homolog B (C. elegans) |
| FBLN1 | fibulin 1 |
| FBXO41 | F-box protein 41 |
| FEZ1 | fasciculation and elongation protein zeta 1 (zygin I) |
| FGD1 | FYVE, RhoGEF and PH domain containing 1 |
| FGFR4 | fibroblast growth factor receptor 4 |
| FHIT | fragile histidine triad |
| FLRT2 | fibronectin leucine rich transmembrane protein 2 |
| FRMD4B | FERM domain containing 4B |
| FSTL3 | follistatin-like 3 (secreted glycoprotein) |
| GABRB2 | gamma-aminobutyric acid (GABA) A receptor, beta 2 |
| HCAR3 | hydroxycarboxylic acid receptor 3 |
| HFE | hemochromatosis |
| HIC2 | hypermethylated in cancer 2 |
| HIST1H3I | histone cluster 1, H3i |
| HLA-DOA | major histocompatibility complex, class II, DO alpha |
| HLA-J | major histocompatibility complex, class I, J (pseudogene) |
| HSD3B1 | hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 |
| IL11 | interleukin 11 |
| IL1RN | interleukin 1 receptor antagonist |
| KCNK2 | potassium channel, two pore domain subfamily K, member 2 |
| KIF21B | kinesin family member 21B |
| KLHL22 | kelch-like family member 22 |
| KRT17 | keratin 17, type I |
| KSR1 | kinase suppressor of ras 1 |
| LAMC2 | laminin, gamma 2 |
| LAMP1 | lysosomal-associated membrane protein 1 |
| LATS1 | large tumor suppressor kinase 1 |
| MAP3K8 | mitogen-activated protein kinase kinase kinase 8 |
| MARK4 | MAP/microtubule affinity-regulating kinase 4 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase |
| MEF2C | myocyte enhancer factor 2C |
| MEGF6 | multiple EGF-like-domains 6 |
| MUC5B | mucin 5B, oligomeric mucus/gel-forming |
| NAB2 | NGFI-A binding protein 2 (EGR1 binding protein 2) |
| NBL1 | neuroblastoma 1, DAN family BMP antagonist |
| NPTX2 | neuronal pentraxin II |
| OCLM | oculomedin |
| OSBPL7 | oxysterol binding protein-like 7 |
| PFKFB2 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2 |
| PLCD1 | phospholipase C, delta 1 |
| POMT2 | protein-O-mannosyltransferase 2 |
| PON1 | paraoxonase 1 |
| RAB33A | RAB33A, member RAS oncogene family |
| RAB40C | RAB40C, member RAS oncogene family |
| RTEL1 | regulator of telomere elongation helicase 1 |
| SH2D1A | SH2 domain containing 1A |
| SLCO1B1 | solute carrier organic anion transporter family, member 1B1 |
| SLCO1C1 | solute carrier organic anion transporter family, member 1C1 |
| SOX2 | SRY (sex determining region Y)-box 2 |
| SPAG8 | sperm associated antigen 8 |
| SPN | sialophorin |
| SPON1 | spondin 1, extracellular matrix protein |
| SPPL2B | signal peptide peptidase like 2B |
| SRSF7 | serine/arginine-rich splicing factor 7 |
| STXBP5L | syntaxin binding protein 5-like |
| TAPBP | TAP binding protein (tapasin) |
| TJAP1 | tight junction associated protein 1 (peripheral) |
| TRIM10 | tripartite motif containing 10 |
| UBE3A | ubiquitin protein ligase E3A |
| UBQLN4 | ubiquilin 4 |
| USP53 | ubiquitin specific peptidase 53 |
| WBP5 | WW domain binding protein 5 |
| WDR62 | WD repeat domain 62 |
| WNT16 | wingless-type MMTV integration site family, member 16 |
| WSCD1 | WSC domain containing 1 |
| XRCC6 | X-ray repair complementing defective repair in Chinese hamster cells 6 |
| ZBTB18 | zinc finger and BTB domain containing 18 |
| ZNF230 | zinc finger protein 230 |
| ZNF343 | zinc finger protein 343 |
| ZNF589 | zinc finger protein 589 |
| Symbol | Name |
|---|---|
| ADTRP | androgen-dependent TFPI-regulating protein |
| AHNAK2 | AHNAK nucleoprotein 2 |
| AKR1B1 | aldo-keto reductase family 1, member B1 (aldose reductase) |
| ARID3B | AT rich interactive domain 3B (BRIGHT-like) |
| C14ORF79 | chromosome 14 open reading frame 79 |
| C19ORF73 | chromosome 19 open reading frame 73 |
| CCDC134 | coiled-coil domain containing 134 |
| CDK6 | cyclin-dependent kinase 6 |
| CGREF1 | cell growth regulator with EF-hand domain 1 |
| CHRNB2 | cholinergic receptor, nicotinic, beta 2 (neuronal) |
| CIC | capicua transcriptional repressor |
| CIDEB | cell death-inducing DFFA-like effector b |
| CLCN6 | chloride channel, voltage-sensitive 6 |
| CLIP4 | CAP-GLY domain containing linker protein family, member 4 |
| CLSTN2 | calsyntenin 2 |
| CRIP1 | cysteine-rich protein 1 (intestinal) |
| CRLF1 | cytokine receptor-like factor 1 |
| CSF1R | colony stimulating factor 1 receptor |
| CTSF | cathepsin F |
| CYP2B7P | cytochrome P450, family 2, subfamily B, polypeptide 7, pseudogene |
| DBF4B | DBF4 zinc finger B |
| DOK5 | docking protein 5 |
| DRD1 | dopamine receptor D1 |
| EPHB6 | EPH receptor B6 |
| EPN1 | epsin 1 |
| FAM198B | family with sequence similarity 198, member B |
| FGF6 | fibroblast growth factor 6 |
| FKBP1B | FK506 binding protein 1B, 12.6 kDa |
| GABRA2 | gamma-aminobutyric acid (GABA) A receptor, alpha 2 |
| GABRR2 | gamma-aminobutyric acid (GABA) A receptor, rho 2 |
| GFI1 | growth factor independent 1 transcription repressor |
| GPR157 | G protein-coupled receptor 157 |
| GPR176 | G protein-coupled receptor 176 |
| GPR3 | G protein-coupled receptor 3 |
| HAMP | hepcidin antimicrobial peptide |
| HDAC7 | histone deacetylase 7 |
| HMHB1 | histocompatibility (minor) HB-1 |
| HOXD11 | homeobox D11 |
| HYI | hydroxypyruvate isomerase (putative) |
| IBSP | integrin-binding sialoprotein |
| IGSF6 | immunoglobulin superfamily, member 6 |
| IL2 | interleukin 2 |
| KDM8 | lysine (K)-specific demethylase 8 |
| LINC00597 | long intergenic non-protein coding RNA 597 |
| LPAR4 | lysophosphatidic acid receptor 4 |
| LTBP2 | latent transforming growth factor beta binding protein 2 |
| MANBA | mannosidase, beta A, lysosomal |
| MBIP | MAP3K12 binding inhibitory protein 1 |
| MNX1 | motor neuron and pancreas homeobox 1 |
| MYL5 | myosin, light chain 5, regulatory |
| NACA2 | nascent polypeptide-associated complex alpha subunit 2 |
| NTF3 | neurotrophin 3 |
| OCA2 | oculocutaneous albinism II |
| OR1G1 | olfactory receptor, family 1, subfamily G, member 1 |
| PCDHA5 | protocadherin alpha 5 |
| PDE6C | phosphodiesterase 6C, cGMP-specific, cone, alpha prime |
| PDK4 | pyruvate dehydrogenase kinase, isozyme 4 |
| PIK3R2 | phosphoinositide-3-kinase, regulatory subunit 2 (beta) |
| PLXNB3 | plexin B3 |
| POU4F2 | POU class 4 homeobox 2 |
| PRSS53 | protease, serine, 53 |
| PYHIN1 | pyrin and HIN domain family, member 1 |
| RAB3D | RAB3D, member RAS oncogene family |
| REM1 | RAS (RAD and GEM)-like GTP-binding 1 |
| RHBDD3 | rhomboid domain containing 3 |
| RHOBTB2 | Rho-related BTB domain containing 2 |
| RIN1 | Ras and Rab interactor 1 |
| RNF125 | ring finger protein 125, E3 ubiquitin protein ligase |
| RNF2 | ring finger protein 2 |
| RNF43 | ring finger protein 43 |
| RRH | retinal pigment epithelium-derived rhodopsin homolog |
| S100A2 | S100 calcium binding protein A2 |
| S100A7 | S100 calcium binding protein A7 |
| S100A9 | S100 calcium binding protein A9 |
| SAG | S-antigen; retina and pineal gland (arrestin) |
| SETD1B | SET domain containing 1B |
| SLC12A8 | solute carrier family 12, member 8 |
| SLC22A18AS | solute carrier family 22 (organic cation transporter), member 18 antisense |
| SSTR5 | somatostatin receptor 5 |
| STAB2 | stabilin 2 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa |
| TEP1 | telomerase-associated protein 1 |
| TMEM53 | transmembrane protein 53 |
| TMEM8B | transmembrane protein 8B |
| TTLL1 | tubulin tyrosine ligase-like family member 1 |
| USP20 | ubiquitin specific peptidase 20 |
| USP27X | ubiquitin specific peptidase 27, X-linked |
| VASH2 | vasohibin 2 |
| VPS9D1 | VPS9 domain containing 1 |
| WNT10B | wingless-type MMTV integration site family, member 10B |
| XDH | xanthine dehydrogenase |
| YY2 | YY2 transcription factor |
| ZBTB48 | zinc finger and BTB domain containing 48 |
| ZNF350 | zinc finger protein 350 |
| ZNF532 | zinc finger protein 532 |
| ZNF574 | zinc finger protein 574 |
| ZNF606 | zinc finger protein 606 |
| ZNF747 | zinc finger protein 747 |