thioproperazine-2236 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
Similar Terms
Downloads & Tools

Genes

196 genes differentially expressed following the thioproperazine-2236 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACRV1 acrosomal vesicle protein 1
ACTC1 actin, alpha, cardiac muscle 1
AGFG1 ArfGAP with FG repeats 1
APOBEC3C apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3C
ARHGAP44 Rho GTPase activating protein 44
ARTN artemin
BCL2L10 BCL2-like 10 (apoptosis facilitator)
BTRC beta-transducin repeat containing E3 ubiquitin protein ligase
C1ORF68 chromosome 1 open reading frame 68
C3 complement component 3
CALCR calcitonin receptor
CAMK2B calcium/calmodulin-dependent protein kinase II beta
CCDC64 coiled-coil domain containing 64
CFDP1 craniofacial development protein 1
CLEC4E C-type lectin domain family 4, member E
COL5A2 collagen, type V, alpha 2
COMMD4 COMM domain containing 4
CTF1 cardiotrophin 1
CYP4F2 cytochrome P450, family 4, subfamily F, polypeptide 2
DGCR8 DGCR8 microprocessor complex subunit
DIMT1 DIM1 dimethyladenosine transferase 1 homolog (S. cerevisiae)
DIS3 DIS3 exosome endoribonuclease and 3'-5' exoribonuclease
DOCK10 dedicator of cytokinesis 10
DOK3 docking protein 3
DPY19L1 dpy-19-like 1 (C. elegans)
ELOVL5 ELOVL fatty acid elongase 5
EPX eosinophil peroxidase
ERCC4 excision repair cross-complementation group 4
FABP2 fatty acid binding protein 2, intestinal
FKRP fukutin related protein
FLOT1 flotillin 1
GAS7 growth arrest-specific 7
GYPB glycophorin B (MNS blood group)
HIPK2 homeodomain interacting protein kinase 2
HIST1H2BN histone cluster 1, H2bn
HOXB9 homeobox B9
HTR4 5-hydroxytryptamine (serotonin) receptor 4, G protein-coupled
INSIG1 insulin induced gene 1
IRF8 interferon regulatory factor 8
KIAA0125 KIAA0125
KLHL20 kelch-like family member 20
LDLR low density lipoprotein receptor
LINC00216 long intergenic non-protein coding RNA 216
MAF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog
MAP2 microtubule-associated protein 2
MOBP myelin-associated oligodendrocyte basic protein
MUC5AC mucin 5AC, oligomeric mucus/gel-forming
MYH14 myosin, heavy chain 14, non-muscle
N4BP2L1 NEDD4 binding protein 2-like 1
NDUFA4L2 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4-like 2
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding)
NF2 neurofibromin 2 (merlin)
NPC1 Niemann-Pick disease, type C1
NR4A1 nuclear receptor subfamily 4, group A, member 1
OR10J1 olfactory receptor, family 10, subfamily J, member 1
OR12D3 olfactory receptor, family 12, subfamily D, member 3
PARD6B par-6 family cell polarity regulator beta
PCDH12 protocadherin 12
PITX1 paired-like homeodomain 1
PLCD1 phospholipase C, delta 1
PLEKHF1 pleckstrin homology domain containing, family F (with FYVE domain) member 1
PLXNB3 plexin B3
POM121L9P POM121 transmembrane nucleoporin-like 9, pseudogene
POU5F1B POU class 5 homeobox 1B
PSAT1 phosphoserine aminotransferase 1
RAB40AL RAB40A, member RAS oncogene family-like
RABGAP1 RAB GTPase activating protein 1
RABGAP1L RAB GTPase activating protein 1-like
RAD52 RAD52 homolog (S. cerevisiae)
RASA3 RAS p21 protein activator 3
RB1 retinoblastoma 1
RHBG Rh family, B glycoprotein (gene/pseudogene)
RLN1 relaxin 1
RMND5A required for meiotic nuclear division 5 homolog A (S. cerevisiae)
RORC RAR-related orphan receptor C
SCN5A sodium channel, voltage gated, type V alpha subunit
SFI1 Sfi1 homolog, spindle assembly associated (yeast)
SKIL SKI-like proto-oncogene
SLCO2A1 solute carrier organic anion transporter family, member 2A1
SNCG synuclein, gamma (breast cancer-specific protein 1)
SORBS2 sorbin and SH3 domain containing 2
SPINK1 serine peptidase inhibitor, Kazal type 1
SUGP1 SURP and G patch domain containing 1
TAOK1 TAO kinase 1
TBCD tubulin folding cofactor D
TCEB3B transcription elongation factor B polypeptide 3B (elongin A2)
TRA2A transformer 2 alpha homolog (Drosophila)
TRD T cell receptor delta locus
TWISTNB TWIST neighbor
UPK2 uroplakin 2
USP12 ubiquitin specific peptidase 12
UTP18 UTP18 small subunit (SSU) processome component homolog (yeast)
VNN2 vanin 2
XPNPEP1 X-prolyl aminopeptidase (aminopeptidase P) 1, soluble
XRCC2 X-ray repair complementing defective repair in Chinese hamster cells 2
ZDHHC17 zinc finger, DHHC-type containing 17
ZSCAN18 zinc finger and SCAN domain containing 18
ZSWIM1 zinc finger, SWIM-type containing 1

decreased expression

Symbol Name
ABCA12 ATP-binding cassette, sub-family A (ABC1), member 12
ABTB2 ankyrin repeat and BTB (POZ) domain containing 2
ACTG2 actin, gamma 2, smooth muscle, enteric
ADAP2 ArfGAP with dual PH domains 2
ANKRD7 ankyrin repeat domain 7
AP1S1 adaptor-related protein complex 1, sigma 1 subunit
ARHGEF1 Rho guanine nucleotide exchange factor (GEF) 1
ATAT1 alpha tubulin acetyltransferase 1
BFSP1 beaded filament structural protein 1, filensin
BMP15 bone morphogenetic protein 15
C11ORF68 chromosome 11 open reading frame 68
C14ORF79 chromosome 14 open reading frame 79
C19ORF73 chromosome 19 open reading frame 73
C8ORF60 chromosome 8 open reading frame 60
CCNO cyclin O
CCP110 centriolar coiled coil protein 110kDa
CCT6B chaperonin containing TCP1, subunit 6B (zeta 2)
CD34 CD34 molecule
CD3D CD3d molecule, delta (CD3-TCR complex)
CD82 CD82 molecule
CDC42EP1 CDC42 effector protein (Rho GTPase binding) 1
CDH10 cadherin 10, type 2 (T2-cadherin)
DGAT1 diacylglycerol O-acyltransferase 1
DOC2A double C2-like domains, alpha
DPY19L1P1 DPY19L1 pseudogene 1
DTX2 deltex 2, E3 ubiquitin ligase
EGFL7 EGF-like-domain, multiple 7
ERCC6 excision repair cross-complementation group 6
ETNK2 ethanolamine kinase 2
EXTL3 exostosin-like glycosyltransferase 3
FAM155B family with sequence similarity 155, member B
FANCE Fanconi anemia, complementation group E
FBXL7 F-box and leucine-rich repeat protein 7
FGL1 fibrinogen-like 1
FLJ11710 uncharacterized protein FLJ11710
FLT4 fms-related tyrosine kinase 4
GADD45G growth arrest and DNA-damage-inducible, gamma
GNG4 guanine nucleotide binding protein (G protein), gamma 4
GPR27 G protein-coupled receptor 27
GPX2 glutathione peroxidase 2
IFT54 intraflagellar transport 54
IL4R interleukin 4 receptor
INF2 inverted formin, FH2 and WH2 domain containing
IRF2BP1 interferon regulatory factor 2 binding protein 1
IRF7 interferon regulatory factor 7
ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)
ITPKB inositol-trisphosphate 3-kinase B
JUNB jun B proto-oncogene
KDM8 lysine (K)-specific demethylase 8
KIAA0319L KIAA0319-like
KIF13B kinesin family member 13B
KLHL25 kelch-like family member 25
LHX1 LIM homeobox 1
LRP2 low density lipoprotein receptor-related protein 2
MICAL1 microtubule associated monooxygenase, calponin and LIM domain containing 1
MINOS1P1 mitochondrial inner membrane organizing system 1 pseudogene 1
MUC3A mucin 3A, cell surface associated
NDE1 nudE neurodevelopment protein 1
NIPAL2 NIPA-like domain containing 2
OAS3 2'-5'-oligoadenylate synthetase 3, 100kDa
OR12D2 olfactory receptor, family 12, subfamily D, member 2 (gene/pseudogene)
OTUB2 OTU deubiquitinase, ubiquitin aldehyde binding 2
PACS1 phosphofurin acidic cluster sorting protein 1
PALM paralemmin
PARG poly (ADP-ribose) glycohydrolase
PGP phosphoglycolate phosphatase
PHC1 polyhomeotic homolog 1 (Drosophila)
PIGN phosphatidylinositol glycan anchor biosynthesis, class N
PIP5K1A phosphatidylinositol-4-phosphate 5-kinase, type I, alpha
PITPNM1 phosphatidylinositol transfer protein, membrane-associated 1
PLEKHB1 pleckstrin homology domain containing, family B (evectins) member 1
POM121 POM121 transmembrane nucleoporin
POMT2 protein-O-mannosyltransferase 2
PRODH proline dehydrogenase (oxidase) 1
PVRL3 poliovirus receptor-related 3
RAB3IL1 RAB3A interacting protein (rabin3)-like 1
RAB40C RAB40C, member RAS oncogene family
RIN2 Ras and Rab interactor 2
RNF208 ring finger protein 208
RPGR retinitis pigmentosa GTPase regulator
SCAMP4 secretory carrier membrane protein 4
SF3A2 splicing factor 3a, subunit 2, 66kDa
SLC35C1 solute carrier family 35 (GDP-fucose transporter), member C1
SLC9A8 solute carrier family 9, subfamily A (NHE8, cation proton antiporter 8), member 8
STMN3 stathmin-like 3
STX1A syntaxin 1A (brain)
TARP TCR gamma alternate reading frame protein
TBX19 T-box 19
TMPRSS4 transmembrane protease, serine 4
UPK3B uroplakin 3B
VWA1 von Willebrand factor A domain containing 1
WNT10B wingless-type MMTV integration site family, member 10B
XYLT2 xylosyltransferase II
ZBTB33 zinc finger and BTB domain containing 33
ZNF205 zinc finger protein 205
ZNF324 zinc finger protein 324
ZNF37BP zinc finger protein 37B, pseudogene
ZNF532 zinc finger protein 532