thioproperazine-6265 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the thioproperazine-6265 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADGRG2 adhesion G protein-coupled receptor G2
AGFG2 ArfGAP with FG repeats 2
AIPL1 aryl hydrocarbon receptor interacting protein-like 1
AKR1C2 aldo-keto reductase family 1, member C2
ALDH3B1 aldehyde dehydrogenase 3 family, member B1
ALDH7A1 aldehyde dehydrogenase 7 family, member A1
AMT aminomethyltransferase
APBB2 amyloid beta (A4) precursor protein-binding, family B, member 2
BAZ1B bromodomain adjacent to zinc finger domain, 1B
BFSP1 beaded filament structural protein 1, filensin
C14ORF1 chromosome 14 open reading frame 1
CASP9 caspase 9, apoptosis-related cysteine peptidase
CCNG2 cyclin G2
CD22 CD22 molecule
CD52 CD52 molecule
CDKAL1 CDK5 regulatory subunit associated protein 1-like 1
CFLAR CASP8 and FADD-like apoptosis regulator
CHKB choline kinase beta
COL6A1 collagen, type VI, alpha 1
CTAGE9 CTAGE family, member 9
DCN decorin
DNAJB4 DnaJ (Hsp40) homolog, subfamily B, member 4
DSC3 desmocollin 3
DUSP4 dual specificity phosphatase 4
EDEM3 ER degradation enhancer, mannosidase alpha-like 3
EHMT2 euchromatic histone-lysine N-methyltransferase 2
EMID1 EMI domain containing 1
EXPH5 exophilin 5
FAM169A family with sequence similarity 169, member A
FBXO11 F-box protein 11
FGF5 fibroblast growth factor 5
FPR1 formyl peptide receptor 1
GALNT12 polypeptide N-acetylgalactosaminyltransferase 12
GCNT1 glucosaminyl (N-acetyl) transferase 1, core 2
GNAS GNAS complex locus
HCFC1 host cell factor C1
HLCS holocarboxylase synthetase (biotin-(proprionyl-CoA-carboxylase (ATP-hydrolysing)) ligase)
ICAM1 intercellular adhesion molecule 1
IGKC immunoglobulin kappa constant
INHBA inhibin, beta A
INPP4A inositol polyphosphate-4-phosphatase, type I, 107kDa
INSIG1 insulin induced gene 1
KCNA5 potassium channel, voltage gated shaker related subfamily A, member 5
KCNJ3 potassium channel, inwardly rectifying subfamily J, member 3
KIF13B kinesin family member 13B
MCF2L MCF.2 cell line derived transforming sequence-like
MECP2 methyl CpG binding protein 2
MID1 midline 1
MTSS1L metastasis suppressor 1-like
MXD3 MAX dimerization protein 3
MXRA8 matrix-remodelling associated 8
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding)
NME5 NME/NM23 family member 5
OASL 2'-5'-oligoadenylate synthetase-like
PAQR6 progestin and adipoQ receptor family member VI
PAX2 paired box 2
PCNX pecanex homolog (Drosophila)
PGAP3 post-GPI attachment to proteins 3
PHLDB1 pleckstrin homology-like domain, family B, member 1
PIK3R2 phosphoinositide-3-kinase, regulatory subunit 2 (beta)
PIP4K2B phosphatidylinositol-5-phosphate 4-kinase, type II, beta
PLA2G3 phospholipase A2, group III
PLCL2 phospholipase C-like 2
PLD1 phospholipase D1, phosphatidylcholine-specific
POLR2J4 polymerase (RNA) II (DNA directed) polypeptide J4, pseudogene
PPT2 palmitoyl-protein thioesterase 2
PTPRS protein tyrosine phosphatase, receptor type, S
RCAN1 regulator of calcineurin 1
RIN2 Ras and Rab interactor 2
RNF216 ring finger protein 216
ROM1 retinal outer segment membrane protein 1
RRBP1 ribosome binding protein 1
SBNO2 strawberry notch homolog 2 (Drosophila)
SCAI suppressor of cancer cell invasion
SCG2 secretogranin II
SCN1B sodium channel, voltage gated, type I beta subunit
SEMA3B sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B
SFTPC surfactant protein C
SLC44A1 solute carrier family 44 (choline transporter), member 1
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SMAD3 SMAD family member 3
STAG3L4 stromal antigen 3-like 4 (pseudogene)
STX2 syntaxin 2
SYBU syntabulin (syntaxin-interacting)
TBC1D5 TBC1 domain family, member 5
TET3 tet methylcytosine dioxygenase 3
TIMM17A translocase of inner mitochondrial membrane 17 homolog A (yeast)
TMEM53 transmembrane protein 53
TRAK1 trafficking protein, kinesin binding 1
TSPAN9 tetraspanin 9
UBOX5 U-box domain containing 5
VAMP5 vesicle-associated membrane protein 5
WFDC2 WAP four-disulfide core domain 2
WNT2B wingless-type MMTV integration site family, member 2B
XIAP X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase
ZBTB39 zinc finger and BTB domain containing 39
ZNF165 zinc finger protein 165
ZNF573 zinc finger protein 573
ZNF710 zinc finger protein 710
ZXDB zinc finger, X-linked, duplicated B

decreased expression

Symbol Name
ABCC4 ATP-binding cassette, sub-family C (CFTR/MRP), member 4
ANKRA2 ankyrin repeat, family A (RFXANK-like), 2
ANXA2P3 annexin A2 pseudogene 3
ASB7 ankyrin repeat and SOCS box containing 7
ASPHD1 aspartate beta-hydroxylase domain containing 1
ATAD5 ATPase family, AAA domain containing 5
ATP7B ATPase, Cu++ transporting, beta polypeptide
BNIP2 BCL2/adenovirus E1B 19kDa interacting protein 2
C19ORF40 chromosome 19 open reading frame 40
C6ORF47 chromosome 6 open reading frame 47
CCNT1 cyclin T1
CDKL3 cyclin-dependent kinase-like 3
CEP131 centrosomal protein 131kDa
CEP170B centrosomal protein 170B
CEP85 centrosomal protein 85kDa
CHST11 carbohydrate (chondroitin 4) sulfotransferase 11
COL9A2 collagen, type IX, alpha 2
DCAF10 DDB1 and CUL4 associated factor 10
DDX31 DEAD (Asp-Glu-Ala-Asp) box polypeptide 31
DDX6 DEAD (Asp-Glu-Ala-Asp) box helicase 6
DECR2 2,4-dienoyl CoA reductase 2, peroxisomal
DOCK1 dedicator of cytokinesis 1
EIF2AK2 eukaryotic translation initiation factor 2-alpha kinase 2
ETAA1 Ewing tumor-associated antigen 1
FAM184A family with sequence similarity 184, member A
FAM86C1 family with sequence similarity 86, member C1
FOCAD focadhesin
GFOD1 glucose-fructose oxidoreductase domain containing 1
GNB1L guanine nucleotide binding protein (G protein), beta polypeptide 1-like
GNG4 guanine nucleotide binding protein (G protein), gamma 4
GSTM2 glutathione S-transferase mu 2 (muscle)
GYS1 glycogen synthase 1 (muscle)
HCFC2 host cell factor C2
HIST1H2AG histone cluster 1, H2ag
HIST1H3G histone cluster 1, H3g
HSD17B1 hydroxysteroid (17-beta) dehydrogenase 1
IL17RA interleukin 17 receptor A
JUNB jun B proto-oncogene
KIF20B kinesin family member 20B
KLC2 kinesin light chain 2
L2HGDH L-2-hydroxyglutarate dehydrogenase
LYPD1 LY6/PLAUR domain containing 1
MAPKBP1 mitogen-activated protein kinase binding protein 1
MBIP MAP3K12 binding inhibitory protein 1
MBTD1 mbt domain containing 1
MED15 mediator complex subunit 15
MED24 mediator complex subunit 24
MIS18BP1 MIS18 binding protein 1
MITF microphthalmia-associated transcription factor
MTERF1 mitochondrial transcription termination factor 1
NARFL nuclear prelamin A recognition factor-like
NCAM2 neural cell adhesion molecule 2
NEK11 NIMA-related kinase 11
OLFML3 olfactomedin-like 3
ORAI3 ORAI calcium release-activated calcium modulator 3
OSMR oncostatin M receptor
P2RX5 purinergic receptor P2X, ligand gated ion channel, 5
PADI1 peptidyl arginine deiminase, type I
PARD6A par-6 family cell polarity regulator alpha
PECR peroxisomal trans-2-enoyl-CoA reductase
PEX26 peroxisomal biogenesis factor 26
PHF21A PHD finger protein 21A
PLAC8 placenta-specific 8
PMM1 phosphomannomutase 1
POTEKP POTE ankyrin domain family, member K, pseudogene
PRRG2 proline rich Gla (G-carboxyglutamic acid) 2
PYCRL pyrroline-5-carboxylate reductase-like
QTRT1 queuine tRNA-ribosyltransferase 1
R3HCC1L R3H domain and coiled-coil containing 1-like
RAMP1 receptor (G protein-coupled) activity modifying protein 1
RBL1 retinoblastoma-like 1
RSF1 remodeling and spacing factor 1
SDF2 stromal cell-derived factor 2
SFT2D2 SFT2 domain containing 2
SGPP1 sphingosine-1-phosphate phosphatase 1
SLC16A2 solute carrier family 16, member 2 (thyroid hormone transporter)
SLC9A1 solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1
SMA4 glucuronidase, beta pseudogene
SND1-IT1 SND1 intronic transcript 1
SRBD1 S1 RNA binding domain 1
STK25 serine/threonine kinase 25
SYCP2 synaptonemal complex protein 2
TGDS TDP-glucose 4,6-dehydratase
THNSL1 threonine synthase-like 1 (S. cerevisiae)
TMEM115 transmembrane protein 115
TPST1 tyrosylprotein sulfotransferase 1
TRAF6 TNF receptor-associated factor 6, E3 ubiquitin protein ligase
TRIM25 tripartite motif containing 25
USP36 ubiquitin specific peptidase 36
VGF VGF nerve growth factor inducible
XAB2 XPA binding protein 2
XRCC2 X-ray repair complementing defective repair in Chinese hamster cells 2
ZBTB38 zinc finger and BTB domain containing 38
ZNF141 zinc finger protein 141
ZNF480 zinc finger protein 480
ZNF552 zinc finger protein 552
ZNF669 zinc finger protein 669
ZNF787 zinc finger protein 787