| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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199 genes differentially expressed following the thiostrepton-2462 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase |
| ACACA | acetyl-CoA carboxylase alpha |
| ACPP | acid phosphatase, prostate |
| ACVR1B | activin A receptor, type IB |
| ANKHD1 | ankyrin repeat and KH domain containing 1 |
| API5 | apoptosis inhibitor 5 |
| AREG | amphiregulin |
| ASAH1 | N-acylsphingosine amidohydrolase (acid ceramidase) 1 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 |
| BAG3 | BCL2-associated athanogene 3 |
| BRF1 | BRF1, RNA polymerase III transcription initiation factor 90 kDa subunit |
| BRF2 | BRF2, RNA polymerase III transcription initiation factor 50 kDa subunit |
| CAMSAP1 | calmodulin regulated spectrin-associated protein 1 |
| CCL27 | chemokine (C-C motif) ligand 27 |
| CCND2 | cyclin D2 |
| CHML | choroideremia-like (Rab escort protein 2) |
| CHRNA2 | cholinergic receptor, nicotinic, alpha 2 (neuronal) |
| CTTN | cortactin |
| DIDO1 | death inducer-obliterator 1 |
| DLEU2 | deleted in lymphocytic leukemia 2 (non-protein coding) |
| DNAJB1 | DnaJ (Hsp40) homolog, subfamily B, member 1 |
| EDRF1 | erythroid differentiation regulatory factor 1 |
| EFNA4 | ephrin-A4 |
| ENTPD7 | ectonucleoside triphosphate diphosphohydrolase 7 |
| EYA3 | EYA transcriptional coactivator and phosphatase 3 |
| FABP3 | fatty acid binding protein 3, muscle and heart |
| FAM49A | family with sequence similarity 49, member A |
| FLOT1 | flotillin 1 |
| FOSL2 | FOS-like antigen 2 |
| FRY | furry homolog (Drosophila) |
| FUT6 | fucosyltransferase 6 (alpha (1,3) fucosyltransferase) |
| GCFC2 | GC-rich sequence DNA-binding factor 2 |
| GCLM | glutamate-cysteine ligase, modifier subunit |
| GFOD2 | glucose-fructose oxidoreductase domain containing 2 |
| GNRH1 | gonadotropin-releasing hormone 1 (luteinizing-releasing hormone) |
| GPATCH2L | G patch domain containing 2-like |
| GPR107 | G protein-coupled receptor 107 |
| GRB10 | growth factor receptor-bound protein 10 |
| GTF3C2 | general transcription factor IIIC, polypeptide 2, beta 110kDa |
| GTPBP1 | GTP binding protein 1 |
| HIST2H2AA3 | histone cluster 2, H2aa3 |
| HMOX1 | heme oxygenase 1 |
| HSPA2 | heat shock 70kDa protein 2 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 |
| HUS1 | HUS1 checkpoint homolog (S. pombe) |
| IDS | iduronate 2-sulfatase |
| IL1RAP | interleukin 1 receptor accessory protein |
| KLF3 | Kruppel-like factor 3 (basic) |
| KLHL20 | kelch-like family member 20 |
| KLHL36 | kelch-like family member 36 |
| KLHL7 | kelch-like family member 7 |
| LILRB3 | leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3 |
| LTBP1 | latent transforming growth factor beta binding protein 1 |
| MIR22HG | MIR22 host gene |
| MKL1 | megakaryoblastic leukemia (translocation) 1 |
| MTMR12 | myotubularin related protein 12 |
| MYB | v-myb avian myeloblastosis viral oncogene homolog |
| NFATC1 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1 |
| NOV | nephroblastoma overexpressed |
| NQO1 | NAD(P)H dehydrogenase, quinone 1 |
| NRP1 | neuropilin 1 |
| NRP2 | neuropilin 2 |
| NUP160 | nucleoporin 160kDa |
| NUP98 | nucleoporin 98kDa |
| OXCT2 | 3-oxoacid CoA transferase 2 |
| PCIF1 | PDX1 C-terminal inhibiting factor 1 |
| PDE4DIP | phosphodiesterase 4D interacting protein |
| PDK3 | pyruvate dehydrogenase kinase, isozyme 3 |
| PDS5A | PDS5 cohesin associated factor A |
| PRKCA | protein kinase C, alpha |
| PSMD11 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 11 |
| RASGRP2 | RAS guanyl releasing protein 2 (calcium and DAG-regulated) |
| RBM34 | RNA binding motif protein 34 |
| RC3H2 | ring finger and CCCH-type domains 2 |
| RIT1 | Ras-like without CAAX 1 |
| RUNX1 | runt-related transcription factor 1 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) |
| SCN10A | sodium channel, voltage gated, type X alpha subunit |
| SEC24D | SEC24 family member D |
| SENP6 | SUMO1/sentrin specific peptidase 6 |
| SETDB1 | SET domain, bifurcated 1 |
| SLC35F5 | solute carrier family 35, member F5 |
| SLC5A2 | solute carrier family 5 (sodium/glucose cotransporter), member 2 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 |
| SMEK2 | SMEK homolog 2, suppressor of mek1 (Dictyostelium) |
| SOCS7 | suppressor of cytokine signaling 7 |
| SON | SON DNA binding protein |
| SORT1 | sortilin 1 |
| TMEM212 | transmembrane protein 212 |
| UBE3B | ubiquitin protein ligase E3B |
| ULBP2 | UL16 binding protein 2 |
| USP5 | ubiquitin specific peptidase 5 (isopeptidase T) |
| WDR33 | WD repeat domain 33 |
| WDR59 | WD repeat domain 59 |
| WHSC1L1 | Wolf-Hirschhorn syndrome candidate 1-like 1 |
| YKT6 | YKT6 v-SNARE homolog (S. cerevisiae) |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 |
| ZNF235 | zinc finger protein 235 |
| ZZEF1 | zinc finger, ZZ-type with EF-hand domain 1 |
| Symbol | Name |
|---|---|
| ALDH2 | aldehyde dehydrogenase 2 family (mitochondrial) |
| ANKRD10 | ankyrin repeat domain 10 |
| ANKRD36B | ankyrin repeat domain 36B |
| ANKRD46 | ankyrin repeat domain 46 |
| ASRGL1 | asparaginase like 1 |
| BACE1 | beta-site APP-cleaving enzyme 1 |
| BBS1 | Bardet-Biedl syndrome 1 |
| C14ORF159 | chromosome 14 open reading frame 159 |
| C1QTNF3 | C1q and tumor necrosis factor related protein 3 |
| CARD8 | caspase recruitment domain family, member 8 |
| CBX5 | chromobox homolog 5 |
| CD1D | CD1d molecule |
| CEL | carboxyl ester lipase |
| CEP68 | centrosomal protein 68kDa |
| CFAP44 | cilia and flagella associated protein 44 |
| CLTCL1 | clathrin, heavy chain-like 1 |
| CSTF3 | cleavage stimulation factor, 3' pre-RNA, subunit 3, 77kDa |
| CTSK | cathepsin K |
| CX3CR1 | chemokine (C-X3-C motif) receptor 1 |
| DCAF10 | DDB1 and CUL4 associated factor 10 |
| DENND2D | DENN/MADD domain containing 2D |
| DEPTOR | DEP domain containing MTOR-interacting protein |
| DET1 | de-etiolated homolog 1 (Arabidopsis) |
| ERMAP | erythroblast membrane-associated protein (Scianna blood group) |
| FADS2 | fatty acid desaturase 2 |
| FAM208A | family with sequence similarity 208, member A |
| GOLGA3 | golgin A3 |
| HDAC4 | histone deacetylase 4 |
| HDHD1 | haloacid dehalogenase-like hydrolase domain containing 1 |
| HIP1 | huntingtin interacting protein 1 |
| IMPA2 | inositol(myo)-1(or 4)-monophosphatase 2 |
| IPCEF1 | interaction protein for cytohesin exchange factors 1 |
| IRF2 | interferon regulatory factor 2 |
| KIAA0556 | KIAA0556 |
| KRCC1 | lysine-rich coiled-coil 1 |
| LINC00339 | long intergenic non-protein coding RNA 339 |
| LINC00341 | long intergenic non-protein coding RNA 341 |
| LOC157562 | uncharacterized LOC157562 |
| LRRK1 | leucine-rich repeat kinase 1 |
| LTB | lymphotoxin beta (TNF superfamily, member 3) |
| LTB4R | leukotriene B4 receptor |
| MBD5 | methyl-CpG binding domain protein 5 |
| MCM3AP-AS1 | MCM3AP antisense RNA 1 |
| MOCOS | molybdenum cofactor sulfurase |
| MORC2 | MORC family CW-type zinc finger 2 |
| MPI | mannose phosphate isomerase |
| MTHFD2L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2-like |
| NDE1 | nudE neurodevelopment protein 1 |
| NFE2 | nuclear factor, erythroid 2 |
| NPIPB3 | nuclear pore complex interacting protein family, member B3 |
| NT5E | 5'-nucleotidase, ecto (CD73) |
| NTSR1 | neurotensin receptor 1 (high affinity) |
| OGDH | oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide) |
| OPN3 | opsin 3 |
| OSBPL1A | oxysterol binding protein-like 1A |
| OSGEPL1 | O-sialoglycoprotein endopeptidase-like 1 |
| P2RX1 | purinergic receptor P2X, ligand gated ion channel, 1 |
| P2RX7 | purinergic receptor P2X, ligand gated ion channel, 7 |
| PCYOX1L | prenylcysteine oxidase 1 like |
| PDE6D | phosphodiesterase 6D, cGMP-specific, rod, delta |
| PIGG | phosphatidylinositol glycan anchor biosynthesis, class G |
| PKD2 | polycystic kidney disease 2 (autosomal dominant) |
| PLAGL1 | pleiomorphic adenoma gene-like 1 |
| PMS1 | PMS1 postmeiotic segregation increased 1 (S. cerevisiae) |
| PPP1R10 | protein phosphatase 1, regulatory subunit 10 |
| PPP3CB | protein phosphatase 3, catalytic subunit, beta isozyme |
| PTER | phosphotriesterase related |
| PTH2R | parathyroid hormone 2 receptor |
| PTPRE | protein tyrosine phosphatase, receptor type, E |
| RAD51D | RAD51 paralog D |
| RFPL1S | RFPL1 antisense RNA 1 |
| RHBDF2 | rhomboid 5 homolog 2 (Drosophila) |
| RPAP2 | RNA polymerase II associated protein 2 |
| RPRD1A | regulation of nuclear pre-mRNA domain containing 1A |
| SAPCD1 | suppressor APC domain containing 1 |
| SH3YL1 | SH3 and SYLF domain containing 1 |
| SLC25A23 | solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23 |
| SLC38A10 | solute carrier family 38, member 10 |
| SLC9A8 | solute carrier family 9, subfamily A (NHE8, cation proton antiporter 8), member 8 |
| SRD5A3 | steroid 5 alpha-reductase 3 |
| SUV420H1 | suppressor of variegation 4-20 homolog 1 (Drosophila) |
| SYK | spleen tyrosine kinase |
| TCFL5 | transcription factor-like 5 (basic helix-loop-helix) |
| TERF2 | telomeric repeat binding factor 2 |
| TERT | telomerase reverse transcriptase |
| TFCP2 | transcription factor CP2 |
| THBS3 | thrombospondin 3 |
| TMEM120B | transmembrane protein 120B |
| TMEM156 | transmembrane protein 156 |
| TPCN1 | two pore segment channel 1 |
| TRIM9 | tripartite motif containing 9 |
| TUBGCP3 | tubulin, gamma complex associated protein 3 |
| UQCC1 | ubiquinol-cytochrome c reductase complex assembly factor 1 |
| WWC3 | WWC family member 3 |
| XYLT1 | xylosyltransferase I |
| ZBED8 | zinc finger, BED-type containing 8 |
| ZHX2 | zinc fingers and homeoboxes 2 |
| ZNF862 | zinc finger protein 862 |
| ZXDC | ZXD family zinc finger C |
