| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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197 genes differentially expressed following the thiostrepton-2823 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABHD4 | abhydrolase domain containing 4 |
| ADAP2 | ArfGAP with dual PH domains 2 |
| AKR1C1 | aldo-keto reductase family 1, member C1 |
| ATF3 | activating transcription factor 3 |
| BAIAP2 | BAI1-associated protein 2 |
| BHLHE40 | basic helix-loop-helix family, member e40 |
| BIN1 | bridging integrator 1 |
| BRF2 | BRF2, RNA polymerase III transcription initiation factor 50 kDa subunit |
| C1ORF54 | chromosome 1 open reading frame 54 |
| CDKN1A | cyclin-dependent kinase inhibitor 1A (p21, Cip1) |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 |
| COL11A2 | collagen, type XI, alpha 2 |
| CPEB1 | cytoplasmic polyadenylation element binding protein 1 |
| CREM | cAMP responsive element modulator |
| CRHR2 | corticotropin releasing hormone receptor 2 |
| CRIP1 | cysteine-rich protein 1 (intestinal) |
| CYP4B1 | cytochrome P450, family 4, subfamily B, polypeptide 1 |
| DDIT3 | DNA-damage-inducible transcript 3 |
| DDIT4 | DNA-damage-inducible transcript 4 |
| DENND6B | DENN/MADD domain containing 6B |
| DNAJB1 | DnaJ (Hsp40) homolog, subfamily B, member 1 |
| DNAJB4 | DnaJ (Hsp40) homolog, subfamily B, member 4 |
| DNAJB9 | DnaJ (Hsp40) homolog, subfamily B, member 9 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 |
| EAF2 | ELL associated factor 2 |
| FAS | Fas cell surface death receptor |
| FOSL1 | FOS-like antigen 1 |
| FOSL2 | FOS-like antigen 2 |
| FYN | FYN proto-oncogene, Src family tyrosine kinase |
| GAD2 | glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa) |
| GADD45A | growth arrest and DNA-damage-inducible, alpha |
| GLIPR1 | GLI pathogenesis-related 1 |
| GLRX | glutaredoxin (thioltransferase) |
| GPR107 | G protein-coupled receptor 107 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) |
| HMOX1 | heme oxygenase 1 |
| HSD17B7 | hydroxysteroid (17-beta) dehydrogenase 7 |
| HSPA13 | heat shock protein 70kDa family, member 13 |
| HSPA1A | heat shock 70kDa protein 1A |
| HSPA1L | heat shock 70kDa protein 1-like |
| HSPA6 | heat shock 70kDa protein 6 (HSP70B') |
| INHBE | inhibin, beta E |
| INSIG1 | insulin induced gene 1 |
| KANK1 | KN motif and ankyrin repeat domains 1 |
| KCTD17 | potassium channel tetramerization domain containing 17 |
| KCTD7 | potassium channel tetramerization domain containing 7 |
| KIAA0368 | KIAA0368 |
| KLF2 | Kruppel-like factor 2 |
| KLHL25 | kelch-like family member 25 |
| LGALS4 | lectin, galactoside-binding, soluble, 4 |
| LMAN1 | lectin, mannose-binding, 1 |
| LOC729164 | hCG1732469 |
| LPIN1 | lipin 1 |
| MAFF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase |
| MIR22HG | MIR22 host gene |
| MITF | microphthalmia-associated transcription factor |
| MLLT11 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 |
| N4BP1 | NEDD4 binding protein 1 |
| NAP1L2 | nucleosome assembly protein 1-like 2 |
| NDRG1 | N-myc downstream regulated 1 |
| NUPR1 | nuclear protein, transcriptional regulator, 1 |
| OSGIN1 | oxidative stress induced growth inhibitor 1 |
| P2RY1 | purinergic receptor P2Y, G-protein coupled, 1 |
| PAPOLG | poly(A) polymerase gamma |
| PBX2 | pre-B-cell leukemia homeobox 2 |
| PDE12 | phosphodiesterase 12 |
| PI4K2A | phosphatidylinositol 4-kinase type 2 alpha |
| PLK3 | polo-like kinase 3 |
| PMAIP1 | phorbol-12-myristate-13-acetate-induced protein 1 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A |
| PRSS16 | protease, serine, 16 (thymus) |
| PSMD11 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 11 |
| RBM5 | RNA binding motif protein 5 |
| RETN | resistin |
| RHOBTB3 | Rho-related BTB domain containing 3 |
| RMND5A | required for meiotic nuclear division 5 homolog A (S. cerevisiae) |
| RND1 | Rho family GTPase 1 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) |
| SGCB | sarcoglycan, beta (43kDa dystrophin-associated glycoprotein) |
| SH3BP2 | SH3-domain binding protein 2 |
| SLC1A4 | solute carrier family 1 (glutamate/neutral amino acid transporter), member 4 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 |
| STYK1 | serine/threonine/tyrosine kinase 1 |
| SUPT6H | suppressor of Ty 6 homolog (S. cerevisiae) |
| TAF1 | TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa |
| TES | testin LIM domain protein |
| TLR2 | toll-like receptor 2 |
| TNFSF9 | tumor necrosis factor (ligand) superfamily, member 9 |
| TRAK1 | trafficking protein, kinesin binding 1 |
| TSC22D3 | TSC22 domain family, member 3 |
| ULBP1 | UL16 binding protein 1 |
| VEGFA | vascular endothelial growth factor A |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 |
| ZNF350 | zinc finger protein 350 |
| ZNF460 | zinc finger protein 460 |
| ZNF750 | zinc finger protein 750 |
| ZNF862 | zinc finger protein 862 |
| Symbol | Name |
|---|---|
| ACADSB | acyl-CoA dehydrogenase, short/branched chain |
| ADCY6 | adenylate cyclase 6 |
| ALDH1A3 | aldehyde dehydrogenase 1 family, member A3 |
| ALKBH4 | alkB, alkylation repair homolog 4 (E. coli) |
| ARL4A | ADP-ribosylation factor-like 4A |
| ARMC6 | armadillo repeat containing 6 |
| BAMBI | BMP and activin membrane-bound inhibitor |
| BCORL1 | BCL6 corepressor-like 1 |
| BRINP3 | bone morphogenetic protein/retinoic acid inducible neural-specific 3 |
| C7ORF43 | chromosome 7 open reading frame 43 |
| CEMIP | cell migration inducing protein, hyaluronan binding |
| CYP26A1 | cytochrome P450, family 26, subfamily A, polypeptide 1 |
| DET1 | de-etiolated homolog 1 (Arabidopsis) |
| DKK1 | dickkopf WNT signaling pathway inhibitor 1 |
| DOLK | dolichol kinase |
| DSCAM | Down syndrome cell adhesion molecule |
| DVL1 | dishevelled segment polarity protein 1 |
| E2F8 | E2F transcription factor 8 |
| EPHA4 | EPH receptor A4 |
| F2R | coagulation factor II (thrombin) receptor |
| FBXL15 | F-box and leucine-rich repeat protein 15 |
| FBXL2 | F-box and leucine-rich repeat protein 2 |
| FBXO31 | F-box protein 31 |
| FBXO5 | F-box protein 5 |
| FBXW12 | F-box and WD repeat domain containing 12 |
| FGGY | FGGY carbohydrate kinase domain containing |
| FLRT3 | fibronectin leucine rich transmembrane protein 3 |
| FPGS | folylpolyglutamate synthase |
| FYCO1 | FYVE and coiled-coil domain containing 1 |
| FZD3 | frizzled class receptor 3 |
| GK3P | glycerol kinase 3 pseudogene |
| GRAMD4 | GRAM domain containing 4 |
| GRB14 | growth factor receptor-bound protein 14 |
| GTF3C5 | general transcription factor IIIC, polypeptide 5, 63kDa |
| HTR1E | 5-hydroxytryptamine (serotonin) receptor 1E, G protein-coupled |
| ICK | intestinal cell (MAK-like) kinase |
| IQCE | IQ motif containing E |
| IQCG | IQ motif containing G |
| IRS1 | insulin receptor substrate 1 |
| IRX5 | iroquois homeobox 5 |
| KCNN4 | potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4 |
| LOC100287590 | uncharacterized LOC100287590 |
| LRRC37A2 | leucine rich repeat containing 37, member A2 |
| LZTS3 | leucine zipper, putative tumor suppressor family member 3 |
| MAVS | mitochondrial antiviral signaling protein |
| MCM9 | minichromosome maintenance complex component 9 |
| MUS81 | MUS81 structure-specific endonuclease subunit |
| MYL5 | myosin, light chain 5, regulatory |
| MYO1E | myosin IE |
| NDE1 | nudE neurodevelopment protein 1 |
| NDST2 | N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 2 |
| NIPAL2 | NIPA-like domain containing 2 |
| NPY1R | neuropeptide Y receptor Y1 |
| PC | pyruvate carboxylase |
| PGP | phosphoglycolate phosphatase |
| PHEX | phosphate regulating endopeptidase homolog, X-linked |
| PLD3 | phospholipase D family, member 3 |
| PLEKHM2 | pleckstrin homology domain containing, family M (with RUN domain) member 2 |
| PLK2 | polo-like kinase 2 |
| PPIP5K2 | diphosphoinositol pentakisphosphate kinase 2 |
| PSRC1 | proline/serine-rich coiled-coil 1 |
| PTK6 | protein tyrosine kinase 6 |
| RASGRP1 | RAS guanyl releasing protein 1 (calcium and DAG-regulated) |
| RBL1 | retinoblastoma-like 1 |
| RHBDF2 | rhomboid 5 homolog 2 (Drosophila) |
| SETD6 | SET domain containing 6 |
| SH2D4A | SH2 domain containing 4A |
| SIDT1 | SID1 transmembrane family, member 1 |
| SLC25A21 | solute carrier family 25 (mitochondrial oxoadipate carrier), member 21 |
| SLC26A2 | solute carrier family 26 (anion exchanger), member 2 |
| SLC2A10 | solute carrier family 2 (facilitated glucose transporter), member 10 |
| SLC35C2 | solute carrier family 35 (GDP-fucose transporter), member C2 |
| SLC6A14 | solute carrier family 6 (amino acid transporter), member 14 |
| SNHG3 | small nucleolar RNA host gene 3 |
| SPATA2L | spermatogenesis associated 2-like |
| STK25 | serine/threonine kinase 25 |
| SYTL2 | synaptotagmin-like 2 |
| TAP1 | transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) |
| TARP | TCR gamma alternate reading frame protein |
| TCTA | T-cell leukemia translocation altered |
| TOE1 | target of EGR1, member 1 (nuclear) |
| TRAF2 | TNF receptor-associated factor 2 |
| TRMT1L | tRNA methyltransferase 1 homolog (S. cerevisiae)-like |
| TRPM4 | transient receptor potential cation channel, subfamily M, member 4 |
| TTI1 | TELO2 interacting protein 1 |
| UNC119 | unc-119 homolog (C. elegans) |
| USB1 | U6 snRNA biogenesis 1 |
| VEGFC | vascular endothelial growth factor C |
| VWA1 | von Willebrand factor A domain containing 1 |
| WDR13 | WD repeat domain 13 |
| WLS | wntless Wnt ligand secretion mediator |
| WRN | Werner syndrome, RecQ helicase-like |
| XYLT2 | xylosyltransferase II |
| ZDHHC14 | zinc finger, DHHC-type containing 14 |
| ZNF268 | zinc finger protein 268 |
| ZNF276 | zinc finger protein 276 |
| ZNF34 | zinc finger protein 34 |
